Incidental Mutation 'R4735:Nwd2'
| ID |
356446 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nwd2
|
| Ensembl Gene |
ENSMUSG00000090061 |
| Gene Name |
NACHT and WD repeat domain containing 2 |
| Synonyms |
3110047P20Rik, B830017A01Rik |
| MMRRC Submission |
041962-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.120)
|
| Stock # |
R4735 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
63806446-63967889 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 63965594 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Glutamine
at position 1726
(R1726Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000124712
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000081747]
[ENSMUST00000159584]
[ENSMUST00000196575]
|
| AlphaFold |
Q6P5U7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000081747
|
| SMART Domains |
Protein: ENSMUSP00000080443
Gene: ENSMUSG00000060512
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF4699
|
9 |
313 |
2.5e-123 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159584
AA Change: R1726Q
PolyPhen 2
Score 0.342 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000124712
Gene: ENSMUSG00000090061
AA Change: R1726Q
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF4062
|
42 |
145 |
1.5e-8 |
PFAM |
|
Blast:AAA
|
408 |
691 |
3e-29 |
BLAST |
|
WD40
|
939 |
995 |
1.06e2 |
SMART |
|
WD40
|
998 |
1037 |
8.96e-2 |
SMART |
|
Blast:WD40
|
1091 |
1126 |
9e-19 |
BLAST |
|
Blast:WD40
|
1129 |
1170 |
1e-17 |
BLAST |
|
Blast:WD40
|
1220 |
1260 |
3e-16 |
BLAST |
|
WD40
|
1263 |
1302 |
3.4e-2 |
SMART |
|
WD40
|
1347 |
1385 |
2.65e1 |
SMART |
|
WD40
|
1386 |
1425 |
1.58e2 |
SMART |
|
Blast:WD40
|
1466 |
1507 |
3e-19 |
BLAST |
|
Blast:WD40
|
1606 |
1644 |
4e-18 |
BLAST |
|
Blast:KR
|
1686 |
1730 |
2e-16 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162757
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000196575
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 95.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 133 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2700049A03Rik |
T |
A |
12: 71,262,897 (GRCm39) |
I1410N |
possibly damaging |
Het |
| 9230106D20Rik |
T |
C |
10: 19,536,001 (GRCm39) |
|
noncoding transcript |
Het |
| Acsf3 |
T |
A |
8: 123,508,218 (GRCm39) |
I238N |
probably damaging |
Het |
| Ahctf1 |
T |
C |
1: 179,580,964 (GRCm39) |
N1746S |
probably benign |
Het |
| Akap3 |
T |
C |
6: 126,842,601 (GRCm39) |
S407P |
probably damaging |
Het |
| Ankfy1 |
T |
A |
11: 72,621,437 (GRCm39) |
M241K |
probably benign |
Het |
| Ano7 |
C |
A |
1: 93,328,216 (GRCm39) |
T622K |
probably benign |
Het |
| App |
T |
C |
16: 84,900,202 (GRCm39) |
T83A |
probably damaging |
Het |
| Arhgef28 |
T |
A |
13: 98,036,237 (GRCm39) |
E1674V |
probably damaging |
Het |
| Asb2 |
C |
A |
12: 103,291,317 (GRCm39) |
V489L |
probably benign |
Het |
| Atrn |
T |
C |
2: 130,862,910 (GRCm39) |
V1330A |
probably benign |
Het |
| Bltp1 |
T |
A |
3: 37,059,116 (GRCm39) |
N3267K |
possibly damaging |
Het |
| Brca1 |
A |
G |
11: 101,383,001 (GRCm39) |
|
probably null |
Het |
| Bspry |
G |
A |
4: 62,404,762 (GRCm39) |
R186Q |
probably damaging |
Het |
| Ccdc168 |
A |
G |
1: 44,100,861 (GRCm39) |
I79T |
probably benign |
Het |
| Cdkn2d |
C |
G |
9: 21,202,185 (GRCm39) |
V21L |
probably benign |
Het |
| Celsr1 |
T |
A |
15: 85,790,230 (GRCm39) |
|
probably null |
Het |
| Ckap4 |
A |
G |
10: 84,369,384 (GRCm39) |
V116A |
possibly damaging |
Het |
| Crb3 |
A |
G |
17: 57,372,207 (GRCm39) |
T85A |
probably damaging |
Het |
| Cyld |
T |
C |
8: 89,456,278 (GRCm39) |
S443P |
probably damaging |
Het |
| Cyp27a1 |
T |
G |
1: 74,776,366 (GRCm39) |
V434G |
possibly damaging |
Het |
| Cyp2b13 |
A |
G |
7: 25,787,720 (GRCm39) |
T339A |
probably benign |
Het |
| Dars1 |
A |
T |
1: 128,303,971 (GRCm39) |
L252* |
probably null |
Het |
| Dcaf10 |
G |
A |
4: 45,372,769 (GRCm39) |
R394Q |
possibly damaging |
Het |
| Ddx55 |
T |
C |
5: 124,704,539 (GRCm39) |
F382S |
probably damaging |
Het |
| Dmtf1l |
T |
A |
X: 125,722,217 (GRCm39) |
K296M |
probably damaging |
Het |
| Dnah7b |
G |
A |
1: 46,106,115 (GRCm39) |
R33Q |
unknown |
Het |
| Dnm2 |
G |
T |
9: 21,385,883 (GRCm39) |
S302I |
probably damaging |
Het |
| Dock4 |
T |
A |
12: 40,681,525 (GRCm39) |
F75I |
probably benign |
Het |
| Dpp10 |
T |
C |
1: 123,326,356 (GRCm39) |
N365S |
probably benign |
Het |
| Dpy19l3 |
G |
T |
7: 35,422,146 (GRCm39) |
Q236K |
probably benign |
Het |
| Dsp |
T |
C |
13: 38,380,016 (GRCm39) |
S1655P |
probably damaging |
Het |
| Ebpl |
A |
T |
14: 61,579,567 (GRCm39) |
I117N |
probably damaging |
Het |
| Edc4 |
T |
A |
8: 106,613,818 (GRCm39) |
V386E |
probably damaging |
Het |
| Eif2s2 |
T |
A |
2: 154,720,467 (GRCm39) |
|
probably null |
Het |
| Elob |
A |
T |
17: 24,046,562 (GRCm39) |
|
probably null |
Het |
| Enox2 |
T |
C |
X: 48,158,554 (GRCm39) |
I71V |
probably damaging |
Het |
| Fez1 |
A |
T |
9: 36,772,141 (GRCm39) |
K149* |
probably null |
Het |
| Fhip2a |
A |
G |
19: 57,359,661 (GRCm39) |
E67G |
probably damaging |
Het |
| Fign |
A |
G |
2: 63,810,782 (GRCm39) |
Y163H |
probably damaging |
Het |
| Flnc |
G |
A |
6: 29,455,812 (GRCm39) |
G2048S |
probably damaging |
Het |
| Fras1 |
A |
G |
5: 96,736,022 (GRCm39) |
D539G |
probably benign |
Het |
| Frmd4b |
T |
C |
6: 97,436,220 (GRCm39) |
|
probably benign |
Het |
| Gan |
C |
T |
8: 117,920,970 (GRCm39) |
T402M |
probably damaging |
Het |
| Ganc |
T |
A |
2: 120,267,104 (GRCm39) |
|
silent |
Het |
| Ggt6 |
C |
A |
11: 72,327,425 (GRCm39) |
R103S |
probably benign |
Het |
| Gli2 |
T |
C |
1: 118,768,052 (GRCm39) |
D725G |
probably damaging |
Het |
| Gm15446 |
T |
A |
5: 110,090,818 (GRCm39) |
C357S |
probably damaging |
Het |
| Gm44501 |
A |
G |
17: 40,889,810 (GRCm39) |
N108S |
probably benign |
Het |
| Gm6309 |
A |
T |
5: 146,105,054 (GRCm39) |
D286E |
probably damaging |
Het |
| Gm6358 |
G |
A |
16: 88,937,848 (GRCm39) |
G29E |
unknown |
Het |
| Grik5 |
A |
G |
7: 24,757,713 (GRCm39) |
I422T |
probably damaging |
Het |
| Grin2c |
A |
G |
11: 115,140,422 (GRCm39) |
I1232T |
possibly damaging |
Het |
| Gsg1 |
C |
T |
6: 135,214,405 (GRCm39) |
R365H |
possibly damaging |
Het |
| H2-M2 |
A |
G |
17: 37,794,135 (GRCm39) |
S30P |
possibly damaging |
Het |
| Hcfc2 |
A |
G |
10: 82,547,914 (GRCm39) |
D302G |
probably damaging |
Het |
| Hk2 |
T |
C |
6: 82,721,955 (GRCm39) |
D128G |
probably benign |
Het |
| Hmcn2 |
C |
A |
2: 31,273,787 (GRCm39) |
Q1380K |
probably benign |
Het |
| Hsp90b1 |
G |
T |
10: 86,529,819 (GRCm39) |
P617T |
probably damaging |
Het |
| Htr1d |
A |
G |
4: 136,170,197 (GRCm39) |
E142G |
probably benign |
Het |
| Hydin |
G |
A |
8: 111,282,264 (GRCm39) |
|
probably null |
Het |
| Il1r1 |
T |
A |
1: 40,332,455 (GRCm39) |
N81K |
probably benign |
Het |
| Inpp5b |
T |
C |
4: 124,677,760 (GRCm39) |
S407P |
probably damaging |
Het |
| Itpkb |
T |
C |
1: 180,245,780 (GRCm39) |
Y766H |
probably damaging |
Het |
| Lyrm2 |
T |
A |
4: 32,801,150 (GRCm39) |
I65N |
probably damaging |
Het |
| Mink1 |
T |
A |
11: 70,500,086 (GRCm39) |
|
probably null |
Het |
| Mkrn3 |
C |
T |
7: 62,069,452 (GRCm39) |
R113H |
probably damaging |
Het |
| Msx3 |
G |
A |
7: 139,627,798 (GRCm39) |
A157V |
probably damaging |
Het |
| Nrxn2 |
T |
G |
19: 6,548,484 (GRCm39) |
V59G |
possibly damaging |
Het |
| Nt5c3b |
T |
C |
11: 100,331,732 (GRCm39) |
T12A |
probably benign |
Het |
| Nynrin |
A |
G |
14: 56,107,625 (GRCm39) |
T911A |
probably benign |
Het |
| Or11i1 |
T |
A |
3: 106,728,996 (GRCm39) |
Y293F |
probably damaging |
Het |
| Or4p18 |
T |
C |
2: 88,233,267 (GRCm39) |
T4A |
probably benign |
Het |
| Or51aa5 |
A |
G |
7: 103,167,030 (GRCm39) |
I187T |
possibly damaging |
Het |
| Or51af1 |
C |
T |
7: 103,141,267 (GRCm39) |
V273M |
possibly damaging |
Het |
| Or52n20 |
C |
T |
7: 104,320,200 (GRCm39) |
T97I |
probably benign |
Het |
| Or5p66 |
A |
G |
7: 107,885,520 (GRCm39) |
M271T |
probably benign |
Het |
| Or6c212 |
A |
G |
10: 129,558,792 (GRCm39) |
I207T |
probably benign |
Het |
| Patl1 |
G |
T |
19: 11,899,869 (GRCm39) |
M220I |
probably benign |
Het |
| Pcnx2 |
A |
T |
8: 126,554,780 (GRCm39) |
|
probably null |
Het |
| Pigr |
A |
T |
1: 130,774,291 (GRCm39) |
T424S |
probably damaging |
Het |
| Pik3c2b |
T |
A |
1: 132,994,787 (GRCm39) |
D250E |
probably benign |
Het |
| Ppa2 |
G |
A |
3: 133,076,186 (GRCm39) |
E272K |
probably benign |
Het |
| Pramel7 |
G |
A |
2: 87,321,187 (GRCm39) |
Q283* |
probably null |
Het |
| Prelid3b |
A |
G |
2: 174,307,683 (GRCm39) |
I81T |
probably benign |
Het |
| Prpf38a |
T |
C |
4: 108,436,242 (GRCm39) |
I24V |
possibly damaging |
Het |
| Ptger2 |
A |
G |
14: 45,239,295 (GRCm39) |
D311G |
possibly damaging |
Het |
| Rab4b |
A |
T |
7: 26,872,191 (GRCm39) |
|
probably benign |
Het |
| Rad17 |
A |
C |
13: 100,755,637 (GRCm39) |
D581E |
probably damaging |
Het |
| Samd11 |
T |
C |
4: 156,333,230 (GRCm39) |
T333A |
probably benign |
Het |
| Scaf4 |
C |
T |
16: 90,049,320 (GRCm39) |
D256N |
unknown |
Het |
| Serinc2 |
A |
G |
4: 130,157,438 (GRCm39) |
F82L |
probably benign |
Het |
| Serpina3g |
T |
A |
12: 104,205,372 (GRCm39) |
V37E |
probably damaging |
Het |
| Serpinb9c |
T |
A |
13: 33,334,254 (GRCm39) |
M263L |
probably benign |
Het |
| Shbg |
A |
G |
11: 69,508,326 (GRCm39) |
I67T |
possibly damaging |
Het |
| Slc25a48 |
G |
A |
13: 56,596,887 (GRCm39) |
|
probably null |
Het |
| Slc25a54 |
T |
C |
3: 109,005,923 (GRCm39) |
W144R |
probably damaging |
Het |
| Slc34a1 |
A |
T |
13: 55,561,397 (GRCm39) |
T621S |
probably benign |
Het |
| Slc6a18 |
A |
T |
13: 73,814,554 (GRCm39) |
C419S |
probably benign |
Het |
| Smc5 |
A |
T |
19: 23,220,069 (GRCm39) |
D389E |
probably benign |
Het |
| Smco3 |
T |
A |
6: 136,808,636 (GRCm39) |
E79D |
probably damaging |
Het |
| Sox5 |
A |
G |
6: 143,906,561 (GRCm39) |
F298S |
probably damaging |
Het |
| Sphkap |
A |
G |
1: 83,256,838 (GRCm39) |
S304P |
probably benign |
Het |
| Tcea2 |
C |
T |
2: 181,328,514 (GRCm39) |
T211I |
probably damaging |
Het |
| Tcf4 |
G |
T |
18: 69,697,226 (GRCm39) |
S34I |
possibly damaging |
Het |
| Tlr4 |
C |
T |
4: 66,759,435 (GRCm39) |
R743C |
probably damaging |
Het |
| Tmem183a |
T |
C |
1: 134,288,620 (GRCm39) |
E67G |
probably damaging |
Het |
| Tpr |
C |
T |
1: 150,317,947 (GRCm39) |
R2152C |
possibly damaging |
Het |
| Trbv15 |
T |
C |
6: 41,118,358 (GRCm39) |
I38T |
probably benign |
Het |
| Treh |
G |
A |
9: 44,592,849 (GRCm39) |
A125T |
probably damaging |
Het |
| Trio |
A |
T |
15: 27,752,875 (GRCm39) |
|
probably null |
Het |
| Ttn |
A |
G |
2: 76,782,293 (GRCm39) |
V981A |
probably damaging |
Het |
| Uap1l1 |
A |
G |
2: 25,252,732 (GRCm39) |
L436P |
probably damaging |
Het |
| Uba7 |
A |
T |
9: 107,854,115 (GRCm39) |
I182F |
possibly damaging |
Het |
| Unc13c |
A |
T |
9: 73,600,620 (GRCm39) |
S1375T |
probably benign |
Het |
| Usp48 |
C |
CT |
4: 137,360,680 (GRCm39) |
|
probably null |
Het |
| Utp20 |
A |
C |
10: 88,652,780 (GRCm39) |
V378G |
possibly damaging |
Het |
| Vmn1r69 |
A |
T |
7: 10,314,926 (GRCm39) |
|
probably benign |
Het |
| Vmn1r86 |
A |
T |
7: 12,836,221 (GRCm39) |
H218Q |
probably damaging |
Het |
| Vmn2r121 |
T |
A |
X: 123,038,335 (GRCm39) |
I562L |
probably benign |
Het |
| Vmn2r45 |
A |
T |
7: 8,486,472 (GRCm39) |
I272N |
probably damaging |
Het |
| Wdr90 |
A |
G |
17: 26,078,424 (GRCm39) |
V320A |
probably benign |
Het |
| Wfikkn1 |
A |
G |
17: 26,097,367 (GRCm39) |
V319A |
possibly damaging |
Het |
| Whamm |
A |
G |
7: 81,221,122 (GRCm39) |
D18G |
probably benign |
Het |
| Wrn |
T |
A |
8: 33,775,250 (GRCm39) |
I605F |
probably damaging |
Het |
| Zdhhc18 |
A |
G |
4: 133,341,178 (GRCm39) |
F232L |
probably damaging |
Het |
| Zfp41 |
T |
C |
15: 75,490,609 (GRCm39) |
I187T |
probably benign |
Het |
| Zfp418 |
A |
G |
7: 7,185,561 (GRCm39) |
Y508C |
probably damaging |
Het |
| Zfp560 |
T |
G |
9: 20,260,347 (GRCm39) |
I172L |
probably benign |
Het |
| Zfp943 |
A |
T |
17: 22,211,391 (GRCm39) |
D159V |
probably benign |
Het |
| Zfp955a |
T |
C |
17: 33,460,696 (GRCm39) |
I479V |
probably benign |
Het |
| Zfpm1 |
T |
A |
8: 123,062,219 (GRCm39) |
V426D |
probably benign |
Het |
| Zic1 |
C |
T |
9: 91,246,558 (GRCm39) |
M171I |
possibly damaging |
Het |
|
| Other mutations in Nwd2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00325:Nwd2
|
APN |
5 |
63,962,818 (GRCm39) |
missense |
probably benign |
|
|
IGL01111:Nwd2
|
APN |
5 |
63,964,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01152:Nwd2
|
APN |
5 |
63,963,872 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL01307:Nwd2
|
APN |
5 |
63,965,626 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01449:Nwd2
|
APN |
5 |
63,962,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01624:Nwd2
|
APN |
5 |
63,964,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01997:Nwd2
|
APN |
5 |
63,961,938 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02007:Nwd2
|
APN |
5 |
63,962,042 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02143:Nwd2
|
APN |
5 |
63,948,996 (GRCm39) |
splice site |
probably null |
|
|
IGL02184:Nwd2
|
APN |
5 |
63,963,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02379:Nwd2
|
APN |
5 |
63,962,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02489:Nwd2
|
APN |
5 |
63,962,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02580:Nwd2
|
APN |
5 |
63,965,512 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02682:Nwd2
|
APN |
5 |
63,962,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02682:Nwd2
|
APN |
5 |
63,962,020 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02891:Nwd2
|
APN |
5 |
63,882,570 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03135:Nwd2
|
APN |
5 |
63,963,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03149:Nwd2
|
APN |
5 |
63,963,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0113:Nwd2
|
UTSW |
5 |
63,965,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0172:Nwd2
|
UTSW |
5 |
63,963,712 (GRCm39) |
missense |
probably benign |
0.44 |
|
R0196:Nwd2
|
UTSW |
5 |
63,963,694 (GRCm39) |
missense |
probably benign |
0.37 |
|
R0239:Nwd2
|
UTSW |
5 |
63,957,467 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0239:Nwd2
|
UTSW |
5 |
63,957,467 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0309:Nwd2
|
UTSW |
5 |
63,964,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0311:Nwd2
|
UTSW |
5 |
63,962,341 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0335:Nwd2
|
UTSW |
5 |
63,962,116 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0384:Nwd2
|
UTSW |
5 |
63,963,025 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0496:Nwd2
|
UTSW |
5 |
63,963,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0497:Nwd2
|
UTSW |
5 |
63,963,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0498:Nwd2
|
UTSW |
5 |
63,963,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0505:Nwd2
|
UTSW |
5 |
63,962,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0655:Nwd2
|
UTSW |
5 |
63,948,928 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R0762:Nwd2
|
UTSW |
5 |
63,957,757 (GRCm39) |
missense |
probably benign |
0.33 |
|
R0835:Nwd2
|
UTSW |
5 |
63,957,473 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0926:Nwd2
|
UTSW |
5 |
63,965,234 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0948:Nwd2
|
UTSW |
5 |
63,964,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1015:Nwd2
|
UTSW |
5 |
63,964,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1086:Nwd2
|
UTSW |
5 |
63,963,917 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1186:Nwd2
|
UTSW |
5 |
63,807,367 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R1305:Nwd2
|
UTSW |
5 |
63,902,540 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1542:Nwd2
|
UTSW |
5 |
63,964,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1548:Nwd2
|
UTSW |
5 |
63,957,525 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1553:Nwd2
|
UTSW |
5 |
63,957,848 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1636:Nwd2
|
UTSW |
5 |
63,964,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1658:Nwd2
|
UTSW |
5 |
63,964,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1763:Nwd2
|
UTSW |
5 |
63,965,614 (GRCm39) |
missense |
probably benign |
|
|
R1800:Nwd2
|
UTSW |
5 |
63,962,917 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1813:Nwd2
|
UTSW |
5 |
63,962,753 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1861:Nwd2
|
UTSW |
5 |
63,962,197 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1889:Nwd2
|
UTSW |
5 |
63,965,009 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1896:Nwd2
|
UTSW |
5 |
63,962,753 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1919:Nwd2
|
UTSW |
5 |
63,963,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1922:Nwd2
|
UTSW |
5 |
63,951,585 (GRCm39) |
missense |
probably benign |
|
|
R2258:Nwd2
|
UTSW |
5 |
63,962,499 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2292:Nwd2
|
UTSW |
5 |
63,962,917 (GRCm39) |
missense |
probably benign |
0.15 |
|
R2504:Nwd2
|
UTSW |
5 |
63,961,717 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2869:Nwd2
|
UTSW |
5 |
63,957,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2869:Nwd2
|
UTSW |
5 |
63,957,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2958:Nwd2
|
UTSW |
5 |
63,963,325 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3034:Nwd2
|
UTSW |
5 |
63,957,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3422:Nwd2
|
UTSW |
5 |
63,882,536 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3423:Nwd2
|
UTSW |
5 |
63,957,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3439:Nwd2
|
UTSW |
5 |
63,961,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4193:Nwd2
|
UTSW |
5 |
63,964,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4254:Nwd2
|
UTSW |
5 |
63,963,889 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R4384:Nwd2
|
UTSW |
5 |
63,963,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4707:Nwd2
|
UTSW |
5 |
63,951,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4713:Nwd2
|
UTSW |
5 |
63,961,803 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4744:Nwd2
|
UTSW |
5 |
63,964,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4795:Nwd2
|
UTSW |
5 |
63,962,776 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4835:Nwd2
|
UTSW |
5 |
63,965,189 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4839:Nwd2
|
UTSW |
5 |
63,962,893 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4896:Nwd2
|
UTSW |
5 |
63,962,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5017:Nwd2
|
UTSW |
5 |
63,807,484 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R5170:Nwd2
|
UTSW |
5 |
63,963,380 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5312:Nwd2
|
UTSW |
5 |
63,963,415 (GRCm39) |
nonsense |
probably null |
|
|
R5330:Nwd2
|
UTSW |
5 |
63,963,859 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5331:Nwd2
|
UTSW |
5 |
63,963,859 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5419:Nwd2
|
UTSW |
5 |
63,965,051 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5434:Nwd2
|
UTSW |
5 |
63,964,991 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5445:Nwd2
|
UTSW |
5 |
63,962,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5761:Nwd2
|
UTSW |
5 |
63,882,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5788:Nwd2
|
UTSW |
5 |
63,965,114 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5907:Nwd2
|
UTSW |
5 |
63,963,326 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5959:Nwd2
|
UTSW |
5 |
63,965,413 (GRCm39) |
missense |
probably benign |
0.32 |
|
R6002:Nwd2
|
UTSW |
5 |
63,962,143 (GRCm39) |
missense |
probably benign |
|
|
R6027:Nwd2
|
UTSW |
5 |
63,965,563 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6082:Nwd2
|
UTSW |
5 |
63,962,374 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6163:Nwd2
|
UTSW |
5 |
63,963,131 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6172:Nwd2
|
UTSW |
5 |
63,964,249 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6334:Nwd2
|
UTSW |
5 |
63,957,596 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6447:Nwd2
|
UTSW |
5 |
63,964,898 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6649:Nwd2
|
UTSW |
5 |
63,882,527 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6855:Nwd2
|
UTSW |
5 |
63,961,794 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7034:Nwd2
|
UTSW |
5 |
63,962,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7168:Nwd2
|
UTSW |
5 |
63,964,837 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7326:Nwd2
|
UTSW |
5 |
63,957,752 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7561:Nwd2
|
UTSW |
5 |
63,964,434 (GRCm39) |
nonsense |
probably null |
|
|
R7576:Nwd2
|
UTSW |
5 |
63,964,736 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7580:Nwd2
|
UTSW |
5 |
63,965,624 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7723:Nwd2
|
UTSW |
5 |
63,965,347 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7769:Nwd2
|
UTSW |
5 |
63,961,847 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8293:Nwd2
|
UTSW |
5 |
63,962,663 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8517:Nwd2
|
UTSW |
5 |
63,948,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8782:Nwd2
|
UTSW |
5 |
63,882,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8792:Nwd2
|
UTSW |
5 |
63,963,047 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8888:Nwd2
|
UTSW |
5 |
63,963,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8895:Nwd2
|
UTSW |
5 |
63,963,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8901:Nwd2
|
UTSW |
5 |
63,963,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8913:Nwd2
|
UTSW |
5 |
63,963,440 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8920:Nwd2
|
UTSW |
5 |
63,948,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9052:Nwd2
|
UTSW |
5 |
63,961,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9362:Nwd2
|
UTSW |
5 |
63,961,747 (GRCm39) |
missense |
probably benign |
0.23 |
|
R9368:Nwd2
|
UTSW |
5 |
63,962,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9377:Nwd2
|
UTSW |
5 |
63,957,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9430:Nwd2
|
UTSW |
5 |
63,964,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9655:Nwd2
|
UTSW |
5 |
63,964,568 (GRCm39) |
nonsense |
probably null |
|
|
R9661:Nwd2
|
UTSW |
5 |
63,957,780 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9736:Nwd2
|
UTSW |
5 |
63,951,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9793:Nwd2
|
UTSW |
5 |
63,964,232 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9795:Nwd2
|
UTSW |
5 |
63,964,232 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF020:Nwd2
|
UTSW |
5 |
63,963,066 (GRCm39) |
nonsense |
probably null |
|
|
X0023:Nwd2
|
UTSW |
5 |
63,964,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Nwd2
|
UTSW |
5 |
63,963,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Nwd2
|
UTSW |
5 |
63,882,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Nwd2
|
UTSW |
5 |
63,964,669 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Nwd2
|
UTSW |
5 |
63,962,327 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTTTCAACAATGCAACGCAGAC -3'
(R):5'- AAGATGGCACCCAAGTCTCATAG -3'
Sequencing Primer
(F):5'- TGCAACGCAGACATCCAGG -3'
(R):5'- ACATCGTGTCAGTTATCTG -3'
|
| Posted On |
2015-11-11 |
Incidental Mutation