Incidental Mutation 'R0403:Atrn'
| ID |
35663 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Atrn
|
| Ensembl Gene |
ENSMUSG00000027312 |
| Gene Name |
attractin |
| Synonyms |
Mgca |
| MMRRC Submission |
038608-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0403 (G1)
|
| Quality Score |
150 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
130748415-130872253 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 130748779 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Tyrosine
at position 100
(C100Y)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000028781
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028781]
[ENSMUST00000146975]
|
| AlphaFold |
Q9WU60 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000028781
AA Change: C100Y
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000028781
Gene: ENSMUSG00000027312
AA Change: C100Y
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
9 |
N/A |
INTRINSIC |
|
low complexity region
|
51 |
97 |
N/A |
INTRINSIC |
|
EGF
|
99 |
129 |
9.85e-5 |
SMART |
|
CUB
|
131 |
247 |
7.85e-18 |
SMART |
|
EGF
|
248 |
282 |
1.47e1 |
SMART |
|
Pfam:Kelch_1
|
339 |
382 |
1.1e-7 |
PFAM |
|
Pfam:Kelch_5
|
389 |
434 |
2.5e-7 |
PFAM |
|
Pfam:Kelch_6
|
390 |
439 |
3.3e-8 |
PFAM |
|
Pfam:Kelch_1
|
553 |
606 |
8.4e-8 |
PFAM |
|
PSI
|
646 |
693 |
7.41e-7 |
SMART |
|
PSI
|
702 |
747 |
8.64e-8 |
SMART |
|
PSI
|
754 |
799 |
2.11e-2 |
SMART |
|
CLECT
|
787 |
918 |
6.14e-20 |
SMART |
|
PSI
|
931 |
982 |
1.11e-5 |
SMART |
|
PSI
|
985 |
1060 |
1.2e-6 |
SMART |
|
EGF_Lam
|
1062 |
1105 |
1.97e-4 |
SMART |
|
EGF_like
|
1108 |
1154 |
3.9e0 |
SMART |
|
transmembrane domain
|
1278 |
1300 |
N/A |
INTRINSIC |
|
low complexity region
|
1310 |
1322 |
N/A |
INTRINSIC |
|
low complexity region
|
1373 |
1385 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000128176
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000133766
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134964
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135110
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000146975
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156982
|
| Meta Mutation Damage Score |
0.9251 |
| Coding Region Coverage |
- 1x: 98.0%
- 3x: 96.8%
- 10x: 93.2%
- 20x: 83.7%
|
| Validation Efficiency |
97% (110/113) |
| MGI Phenotype |
FUNCTION: This gene encodes a widely expressed transmembrane glycoprotein that plays important roles in diverse physiological processes such as regulation of hair pigmentation, monocyte-T cell interaction and control of energy homeostasis. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Certain mutations in this gene are responsible for the mahogany mouse phenotype of dark brown or black coat on a normally agouti background. Mice with loss-of-function mutations in this gene exhibit black coat color, tremor, adiposity, higher basal metabolic rate, juvenile-onset hypomyelination and age-dependent spongiform neurodegeneration of the central nervous system. [provided by RefSeq, Jul 2016]
PHENOTYPE: Some mutant homozygotes exhibit decreases in phaeomelanin synthesis, body weight, and adiposity; increases in locomotion, and abnormal myelination and vacuolation of the central nervous system resulting in tremors. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ace |
A |
G |
11: 105,864,706 (GRCm39) |
|
probably null |
Het |
| Adgrg3 |
C |
T |
8: 95,763,550 (GRCm39) |
L284F |
probably benign |
Het |
| Alkbh8 |
T |
A |
9: 3,385,469 (GRCm39) |
V587E |
probably damaging |
Het |
| Ap4b1 |
T |
A |
3: 103,728,712 (GRCm39) |
M590K |
probably benign |
Het |
| Ap4b1 |
T |
A |
3: 103,726,155 (GRCm39) |
C244S |
probably damaging |
Het |
| Arhgap15 |
C |
T |
2: 43,953,778 (GRCm39) |
T168I |
probably damaging |
Het |
| Atp8b1 |
A |
G |
18: 64,673,381 (GRCm39) |
V997A |
probably damaging |
Het |
| Baiap2l2 |
C |
A |
15: 79,155,416 (GRCm39) |
A151S |
probably benign |
Het |
| Baz2b |
A |
T |
2: 59,799,721 (GRCm39) |
D199E |
possibly damaging |
Het |
| Bmal2 |
T |
A |
6: 146,724,153 (GRCm39) |
H348Q |
probably damaging |
Het |
| Cblb |
A |
G |
16: 51,972,989 (GRCm39) |
D440G |
probably benign |
Het |
| Cdon |
T |
C |
9: 35,384,796 (GRCm39) |
V694A |
probably benign |
Het |
| Cep250 |
A |
T |
2: 155,834,269 (GRCm39) |
R2065W |
probably damaging |
Het |
| Ces2b |
G |
T |
8: 105,560,577 (GRCm39) |
A131S |
probably damaging |
Het |
| Chrna9 |
A |
T |
5: 66,125,235 (GRCm39) |
T59S |
possibly damaging |
Het |
| Cog3 |
T |
A |
14: 75,979,767 (GRCm39) |
|
probably benign |
Het |
| Cpa1 |
G |
A |
6: 30,641,856 (GRCm39) |
V227I |
probably benign |
Het |
| Cyp3a25 |
A |
T |
5: 145,935,323 (GRCm39) |
C98S |
probably damaging |
Het |
| D8Ertd738e |
C |
T |
8: 84,976,230 (GRCm39) |
|
probably null |
Het |
| Ddx60 |
A |
G |
8: 62,447,575 (GRCm39) |
|
probably benign |
Het |
| Dhx16 |
T |
C |
17: 36,193,942 (GRCm39) |
|
probably null |
Het |
| Dnah9 |
T |
A |
11: 65,975,615 (GRCm39) |
Q1478L |
possibly damaging |
Het |
| Dock10 |
T |
C |
1: 80,501,787 (GRCm39) |
Y1434C |
possibly damaging |
Het |
| Enpp3 |
T |
A |
10: 24,680,334 (GRCm39) |
D325V |
probably damaging |
Het |
| Entpd6 |
C |
A |
2: 150,602,090 (GRCm39) |
T194K |
possibly damaging |
Het |
| Fat2 |
A |
T |
11: 55,161,175 (GRCm39) |
V3185E |
probably benign |
Het |
| Flrt1 |
A |
G |
19: 7,073,284 (GRCm39) |
L421P |
probably benign |
Het |
| Fmn2 |
A |
T |
1: 174,521,844 (GRCm39) |
Q1292L |
probably damaging |
Het |
| Fndc1 |
T |
C |
17: 7,972,555 (GRCm39) |
D1459G |
probably damaging |
Het |
| Fndc1 |
T |
C |
17: 7,994,420 (GRCm39) |
|
probably null |
Het |
| Fzr1 |
A |
G |
10: 81,205,202 (GRCm39) |
S265P |
possibly damaging |
Het |
| Gpr142 |
G |
A |
11: 114,696,855 (GRCm39) |
V134M |
probably damaging |
Het |
| Grid2ip |
G |
T |
5: 143,343,375 (GRCm39) |
V24L |
possibly damaging |
Het |
| Herc2 |
G |
A |
7: 55,809,165 (GRCm39) |
R2555H |
probably damaging |
Het |
| Hpdl |
A |
T |
4: 116,677,676 (GRCm39) |
Y262N |
possibly damaging |
Het |
| Htr3a |
A |
G |
9: 48,819,959 (GRCm39) |
V57A |
probably damaging |
Het |
| Igfbp7 |
T |
C |
5: 77,503,438 (GRCm39) |
I186V |
probably benign |
Het |
| Itga2b |
C |
T |
11: 102,358,152 (GRCm39) |
|
probably null |
Het |
| Itgae |
A |
C |
11: 73,014,009 (GRCm39) |
D736A |
possibly damaging |
Het |
| Itpkc |
T |
A |
7: 26,907,770 (GRCm39) |
M645L |
probably benign |
Het |
| Jchain |
T |
C |
5: 88,669,237 (GRCm39) |
R139G |
probably benign |
Het |
| Kif13a |
A |
G |
13: 46,944,877 (GRCm39) |
V908A |
probably damaging |
Het |
| Kif1b |
T |
A |
4: 149,266,424 (GRCm39) |
K389* |
probably null |
Het |
| Klhl12 |
T |
C |
1: 134,413,594 (GRCm39) |
Y360H |
possibly damaging |
Het |
| Knop1 |
G |
A |
7: 118,452,276 (GRCm39) |
R148W |
probably damaging |
Het |
| Lpar1 |
T |
A |
4: 58,487,191 (GRCm39) |
N27Y |
probably damaging |
Het |
| Lpar2 |
T |
A |
8: 70,276,802 (GRCm39) |
V197D |
probably damaging |
Het |
| Lrrc74a |
A |
G |
12: 86,787,753 (GRCm39) |
N128S |
probably damaging |
Het |
| Lum |
G |
T |
10: 97,407,905 (GRCm39) |
V337F |
probably benign |
Het |
| Mag |
T |
C |
7: 30,606,405 (GRCm39) |
D344G |
probably damaging |
Het |
| Maip1 |
G |
A |
1: 57,446,355 (GRCm39) |
A142T |
probably benign |
Het |
| Mlh3 |
A |
G |
12: 85,315,742 (GRCm39) |
V148A |
possibly damaging |
Het |
| Nav3 |
A |
G |
10: 109,602,964 (GRCm39) |
V1195A |
probably damaging |
Het |
| Ncor2 |
A |
G |
5: 125,110,401 (GRCm39) |
S868P |
possibly damaging |
Het |
| Nek1 |
A |
G |
8: 61,559,889 (GRCm39) |
E907G |
probably damaging |
Het |
| Nfam1 |
G |
A |
15: 82,900,580 (GRCm39) |
T134I |
probably benign |
Het |
| Nr0b2 |
T |
C |
4: 133,281,070 (GRCm39) |
V112A |
probably damaging |
Het |
| Nrp1 |
A |
G |
8: 129,184,450 (GRCm39) |
N365S |
probably damaging |
Het |
| Nrsn2 |
T |
C |
2: 152,211,710 (GRCm39) |
Y107C |
probably damaging |
Het |
| Ntng1 |
G |
A |
3: 109,841,927 (GRCm39) |
A282V |
probably damaging |
Het |
| Nxf1 |
T |
C |
19: 8,742,392 (GRCm39) |
I337T |
probably damaging |
Het |
| Obscn |
C |
T |
11: 58,967,366 (GRCm39) |
G479D |
probably damaging |
Het |
| Oprd1 |
T |
A |
4: 131,841,079 (GRCm39) |
D293V |
probably benign |
Het |
| Or13a17 |
T |
C |
7: 140,271,222 (GRCm39) |
S135P |
possibly damaging |
Het |
| P3h2 |
T |
G |
16: 25,788,700 (GRCm39) |
N586H |
possibly damaging |
Het |
| Pcid2 |
T |
C |
8: 13,135,367 (GRCm39) |
Y214C |
probably damaging |
Het |
| Pkd1l3 |
C |
G |
8: 110,350,281 (GRCm39) |
D375E |
possibly damaging |
Het |
| Pkd1l3 |
G |
A |
8: 110,350,295 (GRCm39) |
S380N |
probably benign |
Het |
| Ppic |
C |
A |
18: 53,544,143 (GRCm39) |
G81W |
probably damaging |
Het |
| Ppp2r1a |
C |
A |
17: 21,177,303 (GRCm39) |
P246T |
probably damaging |
Het |
| Ppp4r4 |
T |
G |
12: 103,550,361 (GRCm39) |
S46A |
probably benign |
Het |
| Pramel31 |
A |
G |
4: 144,089,216 (GRCm39) |
N178S |
probably benign |
Het |
| Prkce |
A |
G |
17: 86,476,081 (GRCm39) |
T21A |
probably damaging |
Het |
| Prkg2 |
T |
C |
5: 99,142,504 (GRCm39) |
E210G |
possibly damaging |
Het |
| Prss35 |
A |
G |
9: 86,638,090 (GRCm39) |
M287V |
probably damaging |
Het |
| Psd |
G |
A |
19: 46,309,411 (GRCm39) |
|
probably benign |
Het |
| Ptch2 |
A |
T |
4: 116,968,036 (GRCm39) |
K843* |
probably null |
Het |
| Rab44 |
C |
A |
17: 29,364,235 (GRCm39) |
T603K |
probably damaging |
Het |
| Rasal3 |
T |
A |
17: 32,611,764 (GRCm39) |
|
probably null |
Het |
| Rbbp6 |
A |
G |
7: 122,591,519 (GRCm39) |
T526A |
probably damaging |
Het |
| Ros1 |
A |
T |
10: 52,019,534 (GRCm39) |
|
probably benign |
Het |
| Sec24b |
T |
A |
3: 129,783,325 (GRCm39) |
L1104F |
possibly damaging |
Het |
| Sec24b |
A |
G |
3: 129,793,183 (GRCm39) |
S685P |
probably damaging |
Het |
| Sema6a |
G |
A |
18: 47,423,112 (GRCm39) |
|
probably null |
Het |
| Setmar |
A |
T |
6: 108,052,923 (GRCm39) |
H139L |
probably benign |
Het |
| Slc28a2b |
T |
C |
2: 122,352,335 (GRCm39) |
L364S |
probably damaging |
Het |
| Slc4a7 |
T |
C |
14: 14,766,808 (GRCm38) |
V710A |
probably benign |
Het |
| Smarcc1 |
T |
A |
9: 110,066,876 (GRCm39) |
|
probably null |
Het |
| Smchd1 |
G |
A |
17: 71,701,897 (GRCm39) |
L1032F |
probably damaging |
Het |
| Speg |
T |
C |
1: 75,407,428 (GRCm39) |
|
probably benign |
Het |
| Tasor2 |
A |
T |
13: 3,632,052 (GRCm39) |
Y816* |
probably null |
Het |
| Tcea1 |
C |
G |
1: 4,959,726 (GRCm39) |
R134G |
probably benign |
Het |
| Tchhl1 |
C |
T |
3: 93,378,336 (GRCm39) |
Q347* |
probably null |
Het |
| Tecrl |
A |
T |
5: 83,502,605 (GRCm39) |
|
probably benign |
Het |
| Tepsin |
T |
C |
11: 119,984,508 (GRCm39) |
|
probably benign |
Het |
| Tmem40 |
G |
A |
6: 115,710,946 (GRCm39) |
|
probably benign |
Het |
| Tpr |
G |
A |
1: 150,283,165 (GRCm39) |
|
probably benign |
Het |
| Ttll12 |
A |
T |
15: 83,464,859 (GRCm39) |
|
probably benign |
Het |
| Ttn |
T |
A |
2: 76,739,952 (GRCm39) |
D3529V |
probably benign |
Het |
| Usp34 |
T |
A |
11: 23,283,838 (GRCm39) |
H177Q |
possibly damaging |
Het |
| Vsig10 |
T |
A |
5: 117,476,526 (GRCm39) |
S327T |
probably benign |
Het |
| Zbtb4 |
T |
A |
11: 69,668,465 (GRCm39) |
M396K |
probably damaging |
Het |
| Zfp352 |
C |
T |
4: 90,113,246 (GRCm39) |
T462I |
possibly damaging |
Het |
| Zfp385b |
T |
C |
2: 77,307,189 (GRCm39) |
M145V |
probably damaging |
Het |
| Zfp780b |
C |
A |
7: 27,671,114 (GRCm39) |
V65F |
possibly damaging |
Het |
|
| Other mutations in Atrn |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Atrn
|
APN |
2 |
130,799,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00571:Atrn
|
APN |
2 |
130,836,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01092:Atrn
|
APN |
2 |
130,789,556 (GRCm39) |
nonsense |
probably null |
|
|
IGL01572:Atrn
|
APN |
2 |
130,844,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01924:Atrn
|
APN |
2 |
130,777,485 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02116:Atrn
|
APN |
2 |
130,800,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02372:Atrn
|
APN |
2 |
130,844,674 (GRCm39) |
splice site |
probably benign |
|
|
IGL02390:Atrn
|
APN |
2 |
130,862,897 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02548:Atrn
|
APN |
2 |
130,814,202 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02749:Atrn
|
APN |
2 |
130,789,654 (GRCm39) |
splice site |
probably benign |
|
|
IGL02749:Atrn
|
APN |
2 |
130,812,064 (GRCm39) |
nonsense |
probably null |
|
|
BB010:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB020:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0026:Atrn
|
UTSW |
2 |
130,799,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0479:Atrn
|
UTSW |
2 |
130,841,085 (GRCm39) |
nonsense |
probably null |
|
|
R0544:Atrn
|
UTSW |
2 |
130,828,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0570:Atrn
|
UTSW |
2 |
130,822,054 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0606:Atrn
|
UTSW |
2 |
130,748,776 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0617:Atrn
|
UTSW |
2 |
130,837,005 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0658:Atrn
|
UTSW |
2 |
130,812,147 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1108:Atrn
|
UTSW |
2 |
130,799,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1112:Atrn
|
UTSW |
2 |
130,841,081 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1219:Atrn
|
UTSW |
2 |
130,862,927 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1422:Atrn
|
UTSW |
2 |
130,799,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1524:Atrn
|
UTSW |
2 |
130,799,000 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1653:Atrn
|
UTSW |
2 |
130,777,544 (GRCm39) |
missense |
probably benign |
|
|
R1795:Atrn
|
UTSW |
2 |
130,814,208 (GRCm39) |
missense |
probably benign |
|
|
R1807:Atrn
|
UTSW |
2 |
130,824,692 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1920:Atrn
|
UTSW |
2 |
130,836,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1921:Atrn
|
UTSW |
2 |
130,836,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1935:Atrn
|
UTSW |
2 |
130,799,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1982:Atrn
|
UTSW |
2 |
130,812,142 (GRCm39) |
missense |
probably benign |
|
|
R2000:Atrn
|
UTSW |
2 |
130,777,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2143:Atrn
|
UTSW |
2 |
130,799,916 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2336:Atrn
|
UTSW |
2 |
130,799,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2679:Atrn
|
UTSW |
2 |
130,803,595 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3426:Atrn
|
UTSW |
2 |
130,862,876 (GRCm39) |
missense |
probably benign |
0.06 |
|
R3909:Atrn
|
UTSW |
2 |
130,836,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4077:Atrn
|
UTSW |
2 |
130,806,850 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4162:Atrn
|
UTSW |
2 |
130,836,148 (GRCm39) |
splice site |
probably benign |
|
|
R4195:Atrn
|
UTSW |
2 |
130,775,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4364:Atrn
|
UTSW |
2 |
130,812,128 (GRCm39) |
missense |
probably benign |
0.39 |
|
R4465:Atrn
|
UTSW |
2 |
130,802,388 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4510:Atrn
|
UTSW |
2 |
130,777,497 (GRCm39) |
nonsense |
probably null |
|
|
R4511:Atrn
|
UTSW |
2 |
130,777,497 (GRCm39) |
nonsense |
probably null |
|
|
R4527:Atrn
|
UTSW |
2 |
130,815,424 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4586:Atrn
|
UTSW |
2 |
130,823,962 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4592:Atrn
|
UTSW |
2 |
130,841,050 (GRCm39) |
intron |
probably benign |
|
|
R4658:Atrn
|
UTSW |
2 |
130,775,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4735:Atrn
|
UTSW |
2 |
130,862,910 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4960:Atrn
|
UTSW |
2 |
130,836,967 (GRCm39) |
nonsense |
probably null |
|
|
R4999:Atrn
|
UTSW |
2 |
130,817,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5066:Atrn
|
UTSW |
2 |
130,836,113 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R5080:Atrn
|
UTSW |
2 |
130,812,044 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5141:Atrn
|
UTSW |
2 |
130,841,050 (GRCm39) |
intron |
probably benign |
|
|
R5256:Atrn
|
UTSW |
2 |
130,787,939 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5494:Atrn
|
UTSW |
2 |
130,864,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5678:Atrn
|
UTSW |
2 |
130,811,936 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5752:Atrn
|
UTSW |
2 |
130,748,464 (GRCm39) |
unclassified |
probably benign |
|
|
R5931:Atrn
|
UTSW |
2 |
130,775,356 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6023:Atrn
|
UTSW |
2 |
130,862,900 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6176:Atrn
|
UTSW |
2 |
130,788,011 (GRCm39) |
missense |
probably benign |
0.31 |
|
R6377:Atrn
|
UTSW |
2 |
130,821,889 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6433:Atrn
|
UTSW |
2 |
130,864,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7226:Atrn
|
UTSW |
2 |
130,828,664 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7402:Atrn
|
UTSW |
2 |
130,789,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7541:Atrn
|
UTSW |
2 |
130,803,491 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7587:Atrn
|
UTSW |
2 |
130,822,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7872:Atrn
|
UTSW |
2 |
130,812,147 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7910:Atrn
|
UTSW |
2 |
130,806,807 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7913:Atrn
|
UTSW |
2 |
130,812,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7933:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8044:Atrn
|
UTSW |
2 |
130,777,449 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8079:Atrn
|
UTSW |
2 |
130,855,561 (GRCm39) |
missense |
probably null |
1.00 |
|
R8093:Atrn
|
UTSW |
2 |
130,817,908 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8203:Atrn
|
UTSW |
2 |
130,802,469 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8234:Atrn
|
UTSW |
2 |
130,864,920 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8462:Atrn
|
UTSW |
2 |
130,777,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
130,846,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
130,748,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8831:Atrn
|
UTSW |
2 |
130,748,521 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8937:Atrn
|
UTSW |
2 |
130,841,157 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9161:Atrn
|
UTSW |
2 |
130,777,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9722:Atrn
|
UTSW |
2 |
130,803,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9786:Atrn
|
UTSW |
2 |
130,786,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF009:Atrn
|
UTSW |
2 |
130,748,842 (GRCm39) |
missense |
probably benign |
0.12 |
|
X0024:Atrn
|
UTSW |
2 |
130,800,059 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Atrn
|
UTSW |
2 |
130,815,319 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Atrn
|
UTSW |
2 |
130,788,113 (GRCm39) |
missense |
probably benign |
0.27 |
|
Z1177:Atrn
|
UTSW |
2 |
130,787,962 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- TAGGCGATGTTCATCCGCGCTAAG -3'
(R):5'- AGCCATCATCAAACACAGTGGGG -3'
Sequencing Primer
(F):5'- AAGATggtggcggtggc -3'
(R):5'- ACAGTGGGGCAAATTCTACC -3'
|
| Posted On |
2013-05-09 |
Incidental Mutation