Incidental Mutation 'R4745:Hfm1'
| ID |
356635 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Hfm1
|
| Ensembl Gene |
ENSMUSG00000043410 |
| Gene Name |
HFM1, ATP-dependent DNA helicase homolog |
| Synonyms |
LOC381663, A330009G12Rik, Mer3, Sec63d1 |
| MMRRC Submission |
042028-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.086)
|
| Stock # |
R4745 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
106840192-106926321 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 106901843 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 417
(D417E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112590
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000112690]
[ENSMUST00000117588]
[ENSMUST00000148686]
[ENSMUST00000200249]
|
| AlphaFold |
D3Z4R1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000112690
AA Change: D417E
PolyPhen 2
Score 0.874 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000108310
Gene: ENSMUSG00000043410
AA Change: D417E
| Domain | Start | End | E-Value | Type |
|---|
|
DEXDc
|
276 |
490 |
3.66e-29 |
SMART |
|
HELICc
|
571 |
657 |
1.56e-14 |
SMART |
|
low complexity region
|
751 |
764 |
N/A |
INTRINSIC |
|
Sec63
|
775 |
1090 |
5.66e-60 |
SMART |
|
Blast:Sec63
|
1130 |
1188 |
2e-18 |
BLAST |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000117588
AA Change: D417E
PolyPhen 2
Score 0.874 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000112590
Gene: ENSMUSG00000043410
AA Change: D417E
| Domain | Start | End | E-Value | Type |
|---|
|
DEXDc
|
276 |
490 |
3.66e-29 |
SMART |
|
HELICc
|
571 |
657 |
1.56e-14 |
SMART |
|
low complexity region
|
751 |
764 |
N/A |
INTRINSIC |
|
Sec63
|
775 |
1090 |
5.66e-60 |
SMART |
|
Blast:Sec63
|
1130 |
1188 |
2e-18 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134292
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000137795
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000148686
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000200249
|
| SMART Domains |
Protein: ENSMUSP00000142727
Gene: ENSMUSG00000043410
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ResIII
|
260 |
410 |
9.9e-7 |
PFAM |
|
Pfam:DEAD
|
281 |
410 |
1.5e-19 |
PFAM |
|
| Meta Mutation Damage Score |
0.1023 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.1%
- 20x: 94.8%
|
| Validation Efficiency |
97% (89/92) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is thought to be an ATP-dependent DNA helicase and is expressed mainly in germ-line cells. Defects in this gene are a cause of premature ovarian failure 9 (POF9). [provided by RefSeq, Apr 2014]
PHENOTYPE: Meiosis ais disrupted in homozygotes and bothe sexes are sterile [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca17 |
T |
C |
17: 24,307,453 (GRCm38) |
Y619C |
probably damaging |
Het |
| Adck1 |
A |
G |
12: 88,402,179 (GRCm38) |
|
probably null |
Het |
| Agap3 |
A |
C |
5: 24,451,125 (GRCm38) |
|
probably null |
Het |
| Ankib1 |
A |
T |
5: 3,732,566 (GRCm38) |
H354Q |
probably damaging |
Het |
| Ankrd29 |
T |
G |
18: 12,254,622 (GRCm38) |
N301T |
probably benign |
Het |
| Arhgef4 |
A |
G |
1: 34,807,275 (GRCm38) |
T379A |
probably damaging |
Het |
| Arid1a |
A |
G |
4: 133,753,106 (GRCm38) |
V169A |
probably benign |
Het |
| Armc4 |
G |
A |
18: 7,286,763 (GRCm38) |
T156M |
probably benign |
Het |
| Bag2 |
T |
C |
1: 33,748,336 (GRCm38) |
|
probably null |
Het |
| Bmt2 |
A |
C |
6: 13,628,687 (GRCm38) |
Y332* |
probably null |
Het |
| Bpifb1 |
A |
T |
2: 154,211,581 (GRCm38) |
K248* |
probably null |
Het |
| Caap1 |
C |
A |
4: 94,556,514 (GRCm38) |
|
probably null |
Het |
| Calcr |
T |
A |
6: 3,692,576 (GRCm38) |
Y389F |
probably damaging |
Het |
| Capn1 |
C |
T |
19: 5,993,916 (GRCm38) |
V562I |
probably benign |
Het |
| Ccr1 |
T |
A |
9: 123,963,948 (GRCm38) |
T182S |
probably benign |
Het |
| Ceacam15 |
T |
C |
7: 16,673,334 (GRCm38) |
D86G |
probably benign |
Het |
| Cldnd1 |
C |
T |
16: 58,729,643 (GRCm38) |
T63I |
probably benign |
Het |
| Col12a1 |
A |
T |
9: 79,652,086 (GRCm38) |
|
probably null |
Het |
| Cystm1 |
A |
G |
18: 36,393,295 (GRCm38) |
|
probably benign |
Het |
| Ddx55 |
T |
A |
5: 124,566,965 (GRCm38) |
Y428* |
probably null |
Het |
| Ensa |
G |
A |
3: 95,631,434 (GRCm38) |
G118D |
probably benign |
Het |
| Fam208b |
G |
A |
13: 3,590,069 (GRCm38) |
T356I |
probably benign |
Het |
| Folh1 |
A |
T |
7: 86,723,274 (GRCm38) |
|
probably null |
Het |
| Foxj2 |
C |
A |
6: 122,837,989 (GRCm38) |
P328Q |
probably damaging |
Het |
| Fscn3 |
A |
G |
6: 28,435,628 (GRCm38) |
I417V |
probably damaging |
Het |
| Galnt7 |
T |
C |
8: 57,542,727 (GRCm38) |
|
probably benign |
Het |
| Gm11563 |
T |
A |
11: 99,658,420 (GRCm38) |
*169C |
probably null |
Het |
| Ighv15-2 |
A |
G |
12: 114,564,610 (GRCm38) |
S107P |
probably damaging |
Het |
| Itsn2 |
A |
G |
12: 4,661,944 (GRCm38) |
D904G |
probably damaging |
Het |
| Kif1b |
A |
T |
4: 149,237,882 (GRCm38) |
L860* |
probably null |
Het |
| Krt79 |
T |
C |
15: 101,930,684 (GRCm38) |
E450G |
probably damaging |
Het |
| Lama1 |
T |
C |
17: 67,738,780 (GRCm38) |
S227P |
probably damaging |
Het |
| Lamp5 |
C |
A |
2: 136,060,866 (GRCm38) |
H168Q |
probably benign |
Het |
| Lilra5 |
A |
T |
7: 4,242,077 (GRCm38) |
Q240L |
possibly damaging |
Het |
| Lrp1 |
A |
T |
10: 127,549,944 (GRCm38) |
C3521S |
probably benign |
Het |
| Mroh1 |
T |
A |
15: 76,408,530 (GRCm38) |
|
probably null |
Het |
| Nlrp4g |
A |
T |
9: 124,349,515 (GRCm38) |
|
noncoding transcript |
Het |
| Nr2f6 |
A |
T |
8: 71,378,535 (GRCm38) |
I70N |
probably benign |
Het |
| Nr4a2 |
T |
A |
2: 57,110,151 (GRCm38) |
D311V |
probably damaging |
Het |
| Olfr1490 |
T |
A |
19: 13,655,386 (GRCm38) |
M319K |
probably benign |
Het |
| Olfr248 |
T |
C |
1: 174,391,876 (GRCm38) |
L269P |
probably damaging |
Het |
| Olfr659 |
T |
A |
7: 104,671,504 (GRCm38) |
F267L |
probably damaging |
Het |
| Pcdhb6 |
C |
A |
18: 37,335,373 (GRCm38) |
A449D |
possibly damaging |
Het |
| Pcgf6 |
A |
G |
19: 47,048,106 (GRCm38) |
|
probably null |
Het |
| Prc1 |
C |
A |
7: 80,313,163 (GRCm38) |
H131Q |
probably benign |
Het |
| Ptprq |
C |
A |
10: 107,524,253 (GRCm38) |
R2187L |
probably damaging |
Het |
| Rasl2-9 |
C |
A |
7: 5,125,703 (GRCm38) |
R76L |
possibly damaging |
Het |
| Rdh16f1 |
A |
T |
10: 127,790,816 (GRCm38) |
Y246F |
probably benign |
Het |
| Rit1 |
T |
C |
3: 88,717,675 (GRCm38) |
|
probably benign |
Het |
| Sash1 |
A |
G |
10: 8,729,908 (GRCm38) |
V906A |
probably benign |
Het |
| Scnn1b |
T |
C |
7: 121,902,286 (GRCm38) |
V108A |
probably benign |
Het |
| Sema4f |
A |
T |
6: 82,918,284 (GRCm38) |
I356N |
probably damaging |
Het |
| Shc4 |
A |
T |
2: 125,649,277 (GRCm38) |
L447Q |
probably damaging |
Het |
| Slc24a1 |
T |
C |
9: 64,949,476 (GRCm38) |
M50V |
unknown |
Het |
| Slc28a3 |
T |
A |
13: 58,574,263 (GRCm38) |
D269V |
possibly damaging |
Het |
| Slc35e1 |
A |
G |
8: 72,492,322 (GRCm38) |
S89P |
possibly damaging |
Het |
| Smpd5 |
T |
A |
15: 76,294,808 (GRCm38) |
H125Q |
probably benign |
Het |
| Snapc2 |
A |
G |
8: 4,254,578 (GRCm38) |
T31A |
probably damaging |
Het |
| Sox5 |
G |
C |
6: 143,833,488 (GRCm38) |
H606D |
possibly damaging |
Het |
| Spag6 |
A |
G |
2: 18,737,296 (GRCm38) |
T367A |
possibly damaging |
Het |
| Spag8 |
T |
C |
4: 43,651,636 (GRCm38) |
T413A |
probably damaging |
Het |
| Sptlc3 |
G |
A |
2: 139,547,167 (GRCm38) |
G156R |
probably damaging |
Het |
| Stx19 |
A |
G |
16: 62,822,420 (GRCm38) |
T200A |
probably benign |
Het |
| Tas2r116 |
A |
G |
6: 132,855,705 (GRCm38) |
T90A |
probably benign |
Het |
| Tbl3 |
A |
G |
17: 24,705,330 (GRCm38) |
|
probably benign |
Het |
| Tekt5 |
G |
T |
16: 10,395,194 (GRCm38) |
P76T |
probably damaging |
Het |
| Tjp2 |
C |
T |
19: 24,096,666 (GRCm38) |
E1086K |
possibly damaging |
Het |
| Topbp1 |
T |
C |
9: 103,323,571 (GRCm38) |
L601P |
probably damaging |
Het |
| Trav16 |
T |
A |
14: 53,743,477 (GRCm38) |
M41K |
possibly damaging |
Het |
| Trav6-5 |
C |
A |
14: 53,491,503 (GRCm38) |
N72K |
probably benign |
Het |
| Trpm3 |
C |
G |
19: 22,715,295 (GRCm38) |
T250S |
possibly damaging |
Het |
| Vps35 |
A |
T |
8: 85,261,262 (GRCm38) |
D753E |
probably benign |
Het |
| Vstm2a |
A |
T |
11: 16,263,061 (GRCm38) |
N149Y |
probably damaging |
Het |
| Vwa2 |
G |
T |
19: 56,906,886 (GRCm38) |
M497I |
probably benign |
Het |
| Zfat |
C |
A |
15: 68,180,374 (GRCm38) |
V517L |
probably benign |
Het |
| Zfp169 |
C |
A |
13: 48,490,232 (GRCm38) |
R473L |
possibly damaging |
Het |
| Zfp672 |
T |
C |
11: 58,329,498 (GRCm38) |
|
probably benign |
Het |
| Zranb1 |
T |
C |
7: 132,972,714 (GRCm38) |
V420A |
probably damaging |
Het |
|
| Other mutations in Hfm1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00944:Hfm1
|
APN |
5 |
106,902,130 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
IGL01295:Hfm1
|
APN |
5 |
106,917,606 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
IGL01725:Hfm1
|
APN |
5 |
106,917,379 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01758:Hfm1
|
APN |
5 |
106,904,793 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01911:Hfm1
|
APN |
5 |
106,911,544 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL02337:Hfm1
|
APN |
5 |
106,904,267 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
IGL02472:Hfm1
|
APN |
5 |
106,873,928 (GRCm38) |
splice site |
probably benign |
|
|
IGL02496:Hfm1
|
APN |
5 |
106,901,761 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02545:Hfm1
|
APN |
5 |
106,895,287 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02584:Hfm1
|
APN |
5 |
106,878,662 (GRCm38) |
splice site |
probably null |
|
|
IGL02728:Hfm1
|
APN |
5 |
106,878,823 (GRCm38) |
missense |
probably benign |
0.13 |
|
IGL02881:Hfm1
|
APN |
5 |
106,874,252 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03108:Hfm1
|
APN |
5 |
106,895,934 (GRCm38) |
unclassified |
probably benign |
|
|
IGL03351:Hfm1
|
APN |
5 |
106,911,575 (GRCm38) |
nonsense |
probably null |
|
|
IGL03353:Hfm1
|
APN |
5 |
106,856,929 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0024:Hfm1
|
UTSW |
5 |
106,856,924 (GRCm38) |
missense |
probably benign |
0.41 |
|
R0024:Hfm1
|
UTSW |
5 |
106,856,924 (GRCm38) |
missense |
probably benign |
0.41 |
|
R0094:Hfm1
|
UTSW |
5 |
106,917,478 (GRCm38) |
missense |
probably benign |
|
|
R0633:Hfm1
|
UTSW |
5 |
106,917,601 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R0644:Hfm1
|
UTSW |
5 |
106,898,256 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1078:Hfm1
|
UTSW |
5 |
106,878,830 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1120:Hfm1
|
UTSW |
5 |
106,904,218 (GRCm38) |
splice site |
probably benign |
|
|
R1166:Hfm1
|
UTSW |
5 |
106,911,411 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1242:Hfm1
|
UTSW |
5 |
106,874,901 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1414:Hfm1
|
UTSW |
5 |
106,872,353 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1450:Hfm1
|
UTSW |
5 |
106,918,458 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1529:Hfm1
|
UTSW |
5 |
106,853,123 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1622:Hfm1
|
UTSW |
5 |
106,893,523 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R1710:Hfm1
|
UTSW |
5 |
106,896,003 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1710:Hfm1
|
UTSW |
5 |
106,880,514 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1757:Hfm1
|
UTSW |
5 |
106,880,360 (GRCm38) |
splice site |
probably null |
|
|
R1856:Hfm1
|
UTSW |
5 |
106,847,676 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1984:Hfm1
|
UTSW |
5 |
106,898,576 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1985:Hfm1
|
UTSW |
5 |
106,898,576 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R2040:Hfm1
|
UTSW |
5 |
106,901,818 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2122:Hfm1
|
UTSW |
5 |
106,896,255 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2426:Hfm1
|
UTSW |
5 |
106,847,653 (GRCm38) |
splice site |
probably null |
|
|
R2474:Hfm1
|
UTSW |
5 |
106,872,416 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R2926:Hfm1
|
UTSW |
5 |
106,874,282 (GRCm38) |
nonsense |
probably null |
|
|
R2944:Hfm1
|
UTSW |
5 |
106,872,330 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3705:Hfm1
|
UTSW |
5 |
106,892,839 (GRCm38) |
unclassified |
probably benign |
|
|
R4256:Hfm1
|
UTSW |
5 |
106,904,797 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R4455:Hfm1
|
UTSW |
5 |
106,886,508 (GRCm38) |
splice site |
probably null |
|
|
R4538:Hfm1
|
UTSW |
5 |
106,874,890 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
R4540:Hfm1
|
UTSW |
5 |
106,874,221 (GRCm38) |
nonsense |
probably null |
|
|
R4591:Hfm1
|
UTSW |
5 |
106,847,667 (GRCm38) |
missense |
probably benign |
0.08 |
|
R4747:Hfm1
|
UTSW |
5 |
106,917,523 (GRCm38) |
missense |
probably benign |
|
|
R4765:Hfm1
|
UTSW |
5 |
106,842,539 (GRCm38) |
missense |
probably benign |
0.21 |
|
R4821:Hfm1
|
UTSW |
5 |
106,854,740 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4842:Hfm1
|
UTSW |
5 |
106,892,751 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4944:Hfm1
|
UTSW |
5 |
106,874,213 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R5093:Hfm1
|
UTSW |
5 |
106,901,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5399:Hfm1
|
UTSW |
5 |
106,917,562 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R5414:Hfm1
|
UTSW |
5 |
106,902,076 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5436:Hfm1
|
UTSW |
5 |
106,892,772 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R5459:Hfm1
|
UTSW |
5 |
106,904,763 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5485:Hfm1
|
UTSW |
5 |
106,847,662 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5585:Hfm1
|
UTSW |
5 |
106,911,439 (GRCm38) |
missense |
probably benign |
0.05 |
|
R5631:Hfm1
|
UTSW |
5 |
106,904,763 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5705:Hfm1
|
UTSW |
5 |
106,911,453 (GRCm38) |
missense |
probably benign |
0.21 |
|
R5804:Hfm1
|
UTSW |
5 |
106,878,589 (GRCm38) |
splice site |
probably null |
|
|
R5959:Hfm1
|
UTSW |
5 |
106,874,917 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6046:Hfm1
|
UTSW |
5 |
106,898,643 (GRCm38) |
splice site |
probably null |
|
|
R6191:Hfm1
|
UTSW |
5 |
106,886,553 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R6345:Hfm1
|
UTSW |
5 |
106,841,638 (GRCm38) |
missense |
probably benign |
|
|
R6580:Hfm1
|
UTSW |
5 |
106,847,709 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6651:Hfm1
|
UTSW |
5 |
106,847,687 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6761:Hfm1
|
UTSW |
5 |
106,895,279 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6835:Hfm1
|
UTSW |
5 |
106,878,815 (GRCm38) |
nonsense |
probably null |
|
|
R6891:Hfm1
|
UTSW |
5 |
106,917,374 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R6924:Hfm1
|
UTSW |
5 |
106,850,410 (GRCm38) |
splice site |
probably null |
|
|
R6980:Hfm1
|
UTSW |
5 |
106,880,477 (GRCm38) |
missense |
probably benign |
0.31 |
|
R7054:Hfm1
|
UTSW |
5 |
106,896,043 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7058:Hfm1
|
UTSW |
5 |
106,911,440 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7189:Hfm1
|
UTSW |
5 |
106,901,703 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7250:Hfm1
|
UTSW |
5 |
106,904,331 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7376:Hfm1
|
UTSW |
5 |
106,895,218 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R7577:Hfm1
|
UTSW |
5 |
106,896,043 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7636:Hfm1
|
UTSW |
5 |
106,917,466 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7639:Hfm1
|
UTSW |
5 |
106,898,475 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R7639:Hfm1
|
UTSW |
5 |
106,889,925 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7763:Hfm1
|
UTSW |
5 |
106,881,861 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7828:Hfm1
|
UTSW |
5 |
106,881,791 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7905:Hfm1
|
UTSW |
5 |
106,898,553 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8160:Hfm1
|
UTSW |
5 |
106,896,033 (GRCm38) |
missense |
probably null |
0.00 |
|
R8477:Hfm1
|
UTSW |
5 |
106,881,818 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8739:Hfm1
|
UTSW |
5 |
106,898,505 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R8968:Hfm1
|
UTSW |
5 |
106,917,573 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9072:Hfm1
|
UTSW |
5 |
106,898,280 (GRCm38) |
missense |
probably benign |
0.04 |
|
R9073:Hfm1
|
UTSW |
5 |
106,898,280 (GRCm38) |
missense |
probably benign |
0.04 |
|
R9152:Hfm1
|
UTSW |
5 |
106,841,745 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9234:Hfm1
|
UTSW |
5 |
106,893,468 (GRCm38) |
missense |
probably benign |
|
|
R9244:Hfm1
|
UTSW |
5 |
106,874,900 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9576:Hfm1
|
UTSW |
5 |
106,874,072 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9649:Hfm1
|
UTSW |
5 |
106,918,463 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R9743:Hfm1
|
UTSW |
5 |
106,874,259 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R9782:Hfm1
|
UTSW |
5 |
106,874,030 (GRCm38) |
missense |
probably benign |
0.38 |
|
R9789:Hfm1
|
UTSW |
5 |
106,917,480 (GRCm38) |
missense |
probably benign |
0.00 |
|
Z1177:Hfm1
|
UTSW |
5 |
106,871,820 (GRCm38) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CAACTTCTCTGAGACCAAATTGAC -3'
(R):5'- AGGTAGTAAACACGTTCACTTTCAG -3'
Sequencing Primer
(F):5'- CTGAGACCAAATTGACTAAATATCCC -3'
(R):5'- CGTTCACTTTCAGAGATAAACACAG -3'
|
| Posted On |
2015-11-11 |
Incidental Mutation