Incidental Mutation 'R4747:Ttc6'
| ID |
357217 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ttc6
|
| Ensembl Gene |
ENSMUSG00000046782 |
| Gene Name |
tetratricopeptide repeat domain 6 |
| Synonyms |
LOC217602, Gm9813, EG639426, 4921506M07Rik, AU024163 |
| MMRRC Submission |
042029-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.119)
|
| Stock # |
R4747 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
12 |
| Chromosomal Location |
57610899-57784714 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 57721478 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 989
(D989V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000134273
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000172939]
|
| AlphaFold |
G3UYY4 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000172939
AA Change: D989V
PolyPhen 2
Score 0.863 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000134273
Gene: ENSMUSG00000046782
AA Change: D989V
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
18 |
42 |
N/A |
INTRINSIC |
|
low complexity region
|
146 |
162 |
N/A |
INTRINSIC |
|
low complexity region
|
188 |
212 |
N/A |
INTRINSIC |
|
low complexity region
|
227 |
238 |
N/A |
INTRINSIC |
|
low complexity region
|
486 |
495 |
N/A |
INTRINSIC |
|
low complexity region
|
670 |
685 |
N/A |
INTRINSIC |
|
low complexity region
|
733 |
740 |
N/A |
INTRINSIC |
|
TPR
|
889 |
922 |
2e-4 |
SMART |
|
TPR
|
957 |
989 |
2.36e1 |
SMART |
|
TPR
|
990 |
1022 |
2.63e1 |
SMART |
|
TPR
|
1023 |
1056 |
9.39e-1 |
SMART |
|
TPR
|
1057 |
1090 |
3.78e-5 |
SMART |
|
Blast:TPR
|
1126 |
1157 |
1e-11 |
BLAST |
|
SEL1
|
1160 |
1192 |
3.39e1 |
SMART |
|
TPR
|
1160 |
1194 |
4.44e1 |
SMART |
|
TPR
|
1195 |
1228 |
7.87e0 |
SMART |
|
Blast:TPR
|
1229 |
1262 |
1e-11 |
BLAST |
|
TPR
|
1297 |
1330 |
1.24e0 |
SMART |
|
SEL1
|
1341 |
1372 |
9.26e-1 |
SMART |
|
TPR
|
1341 |
1374 |
3.45e-8 |
SMART |
|
TPR
|
1375 |
1407 |
8.76e-1 |
SMART |
|
TPR
|
1408 |
1441 |
1.45e-1 |
SMART |
|
TPR
|
1442 |
1475 |
1.36e1 |
SMART |
|
TPR
|
1476 |
1509 |
7.34e-3 |
SMART |
|
TPR
|
1513 |
1546 |
1.01e0 |
SMART |
|
TPR
|
1547 |
1580 |
2.55e-2 |
SMART |
|
TPR
|
1581 |
1617 |
2.43e1 |
SMART |
|
Blast:TPR
|
1618 |
1651 |
4e-12 |
BLAST |
|
TPR
|
1652 |
1685 |
7.87e0 |
SMART |
|
TPR
|
1686 |
1718 |
2.35e-1 |
SMART |
|
SEL1
|
1719 |
1750 |
1.21e2 |
SMART |
|
TPR
|
1719 |
1752 |
1.65e-5 |
SMART |
|
TPR
|
1753 |
1786 |
1.66e-1 |
SMART |
|
TPR
|
1787 |
1820 |
1.45e-1 |
SMART |
|
TPR
|
1821 |
1854 |
3.27e0 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.4%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933402D24Rik |
A |
G |
1: 63,795,568 (GRCm39) |
|
probably benign |
Het |
| Acadvl |
G |
T |
11: 69,903,334 (GRCm39) |
N340K |
probably damaging |
Het |
| Adgrl4 |
T |
A |
3: 151,213,077 (GRCm39) |
N372K |
probably benign |
Het |
| Adh1 |
G |
A |
3: 137,994,642 (GRCm39) |
G321S |
probably damaging |
Het |
| Ankrd26 |
G |
T |
6: 118,504,718 (GRCm39) |
N730K |
probably benign |
Het |
| Aoc2 |
A |
T |
11: 101,219,646 (GRCm39) |
|
probably null |
Het |
| Arhgef4 |
A |
G |
1: 34,762,355 (GRCm39) |
E537G |
unknown |
Het |
| Ccdc7b |
T |
C |
8: 129,904,716 (GRCm39) |
V118A |
probably benign |
Het |
| Ccdc88b |
T |
A |
19: 6,833,509 (GRCm39) |
R219W |
probably damaging |
Het |
| Ccdc97 |
T |
C |
7: 25,418,348 (GRCm39) |
|
probably null |
Het |
| Cfhr4 |
A |
T |
1: 139,625,922 (GRCm39) |
C792S |
probably damaging |
Het |
| Ciao3 |
A |
T |
17: 25,999,327 (GRCm39) |
Y247F |
probably benign |
Het |
| Cnot1 |
T |
C |
8: 96,501,310 (GRCm39) |
N86S |
probably benign |
Het |
| Comp |
T |
C |
8: 70,829,352 (GRCm39) |
C310R |
probably damaging |
Het |
| Crtc2 |
A |
T |
3: 90,167,518 (GRCm39) |
N281Y |
probably damaging |
Het |
| Cryl1 |
T |
C |
14: 57,550,559 (GRCm39) |
K102E |
probably damaging |
Het |
| Csf2ra |
G |
A |
19: 61,214,491 (GRCm39) |
R225* |
probably null |
Het |
| Dao |
A |
T |
5: 114,150,693 (GRCm39) |
D99V |
probably benign |
Het |
| Dgkd |
A |
G |
1: 87,861,889 (GRCm39) |
T815A |
probably damaging |
Het |
| Dhrs7 |
T |
C |
12: 72,699,892 (GRCm39) |
T247A |
probably benign |
Het |
| Dnah7c |
G |
C |
1: 46,572,328 (GRCm39) |
D934H |
probably damaging |
Het |
| Dnajc15 |
T |
C |
14: 78,081,896 (GRCm39) |
Y82C |
probably benign |
Het |
| Dnajc4 |
T |
C |
19: 6,966,872 (GRCm39) |
Q152R |
probably damaging |
Het |
| Dsc1 |
T |
C |
18: 20,227,615 (GRCm39) |
K541R |
probably damaging |
Het |
| Elp4 |
G |
A |
2: 105,624,952 (GRCm39) |
R196C |
probably damaging |
Het |
| Epha8 |
GC |
G |
4: 136,666,006 (GRCm39) |
|
probably null |
Het |
| Ercc6 |
T |
C |
14: 32,291,864 (GRCm39) |
V1076A |
probably benign |
Het |
| Fgd4 |
T |
C |
16: 16,241,793 (GRCm39) |
Y677C |
probably damaging |
Het |
| Fndc3b |
C |
A |
3: 27,483,114 (GRCm39) |
C1028F |
probably damaging |
Het |
| Folr1 |
T |
A |
7: 101,513,184 (GRCm39) |
D37V |
probably damaging |
Het |
| Gabrr3 |
T |
A |
16: 59,268,277 (GRCm39) |
|
probably null |
Het |
| Garem1 |
C |
A |
18: 21,263,000 (GRCm39) |
V605L |
probably benign |
Het |
| Gbp7 |
A |
T |
3: 142,248,778 (GRCm39) |
D347V |
probably damaging |
Het |
| Gdpd4 |
A |
G |
7: 97,610,840 (GRCm39) |
T87A |
possibly damaging |
Het |
| Gm12258 |
C |
A |
11: 58,750,422 (GRCm39) |
H532Q |
probably damaging |
Het |
| Herc2 |
A |
G |
7: 55,756,141 (GRCm39) |
E727G |
possibly damaging |
Het |
| Hfm1 |
G |
A |
5: 107,065,389 (GRCm39) |
H97Y |
probably benign |
Het |
| Idua |
G |
T |
5: 108,828,902 (GRCm39) |
R335L |
probably damaging |
Het |
| Ifi207 |
A |
G |
1: 173,556,633 (GRCm39) |
S702P |
probably benign |
Het |
| Kif16b |
A |
T |
2: 142,699,346 (GRCm39) |
V78D |
probably damaging |
Het |
| Klra17 |
T |
A |
6: 129,849,232 (GRCm39) |
D114V |
probably damaging |
Het |
| Krt76 |
A |
G |
15: 101,794,180 (GRCm39) |
S481P |
probably damaging |
Het |
| Lhfpl5 |
A |
G |
17: 28,798,950 (GRCm39) |
D153G |
probably damaging |
Het |
| Med21 |
T |
A |
6: 146,550,700 (GRCm39) |
D70E |
possibly damaging |
Het |
| Mroh3 |
A |
T |
1: 136,113,237 (GRCm39) |
M739K |
probably benign |
Het |
| Myo1a |
A |
G |
10: 127,550,307 (GRCm39) |
E549G |
probably damaging |
Het |
| Neu1 |
A |
G |
17: 35,153,359 (GRCm39) |
D294G |
possibly damaging |
Het |
| Nmur2 |
A |
T |
11: 55,931,105 (GRCm39) |
I202K |
probably benign |
Het |
| Nop2 |
T |
A |
6: 125,114,057 (GRCm39) |
D174E |
probably benign |
Het |
| Ogfr |
A |
T |
2: 180,236,216 (GRCm39) |
H267L |
probably damaging |
Het |
| Or10p1 |
G |
T |
10: 129,444,053 (GRCm39) |
A99E |
possibly damaging |
Het |
| Or5m8 |
A |
G |
2: 85,822,271 (GRCm39) |
T37A |
probably damaging |
Het |
| P2ry13 |
T |
A |
3: 59,117,308 (GRCm39) |
I157F |
probably benign |
Het |
| Pank4 |
T |
C |
4: 155,063,989 (GRCm39) |
V660A |
probably damaging |
Het |
| Pax6 |
C |
A |
2: 105,526,847 (GRCm39) |
P251Q |
probably benign |
Het |
| Pcdhb13 |
T |
C |
18: 37,577,868 (GRCm39) |
Y749H |
probably damaging |
Het |
| Pcdhga3 |
C |
A |
18: 37,809,799 (GRCm39) |
Q751K |
probably benign |
Het |
| Pcnt |
C |
T |
10: 76,272,299 (GRCm39) |
E186K |
possibly damaging |
Het |
| Pecam1 |
A |
T |
11: 106,575,072 (GRCm39) |
F613I |
probably benign |
Het |
| Pias2 |
T |
C |
18: 77,240,488 (GRCm39) |
*615Q |
probably null |
Het |
| Plb1 |
A |
T |
5: 32,507,003 (GRCm39) |
M1193L |
probably benign |
Het |
| Pomgnt1 |
T |
C |
4: 116,013,396 (GRCm39) |
L506P |
probably damaging |
Het |
| Qrfp |
T |
C |
2: 31,698,852 (GRCm39) |
T27A |
probably damaging |
Het |
| Relb |
C |
A |
7: 19,361,847 (GRCm39) |
|
probably null |
Het |
| Resf1 |
A |
T |
6: 149,228,392 (GRCm39) |
E479D |
probably damaging |
Het |
| Rgl1 |
G |
T |
1: 152,400,450 (GRCm39) |
C685* |
probably null |
Het |
| Ric8b |
A |
G |
10: 84,753,628 (GRCm39) |
Y8C |
probably benign |
Het |
| Rrp36 |
G |
A |
17: 46,980,893 (GRCm39) |
A161V |
possibly damaging |
Het |
| Samd9l |
G |
A |
6: 3,375,504 (GRCm39) |
Q586* |
probably null |
Het |
| Sbf1 |
C |
T |
15: 89,186,916 (GRCm39) |
D821N |
probably damaging |
Het |
| Septin8 |
G |
C |
11: 53,427,545 (GRCm39) |
A255P |
probably damaging |
Het |
| Skp2 |
T |
C |
15: 9,113,927 (GRCm39) |
T329A |
possibly damaging |
Het |
| Slc15a2 |
C |
T |
16: 36,592,498 (GRCm39) |
V220M |
probably damaging |
Het |
| Slc25a11 |
T |
A |
11: 70,536,782 (GRCm39) |
T63S |
possibly damaging |
Het |
| Sowahc |
T |
C |
10: 59,058,983 (GRCm39) |
I373T |
probably benign |
Het |
| Sptbn2 |
T |
A |
19: 4,798,182 (GRCm39) |
M1969K |
probably benign |
Het |
| St14 |
G |
A |
9: 31,015,053 (GRCm39) |
T315M |
possibly damaging |
Het |
| Tagap |
G |
A |
17: 8,151,030 (GRCm39) |
R284H |
probably benign |
Het |
| Tdpoz3 |
T |
A |
3: 93,733,476 (GRCm39) |
S50R |
possibly damaging |
Het |
| Thoc5 |
A |
G |
11: 4,854,187 (GRCm39) |
D182G |
probably damaging |
Het |
| Tinag |
A |
G |
9: 76,904,238 (GRCm39) |
V395A |
probably benign |
Het |
| Tmc8 |
A |
G |
11: 117,683,550 (GRCm39) |
S702G |
probably benign |
Het |
| Tmem202 |
A |
G |
9: 59,426,477 (GRCm39) |
S230P |
possibly damaging |
Het |
| Tmem203 |
T |
C |
2: 25,145,764 (GRCm39) |
V28A |
probably benign |
Het |
| Traf3ip1 |
A |
T |
1: 91,455,479 (GRCm39) |
S647C |
probably damaging |
Het |
| Tram1 |
A |
T |
1: 13,659,870 (GRCm39) |
I26N |
probably damaging |
Het |
| Ttll6 |
A |
G |
11: 96,036,372 (GRCm39) |
T334A |
possibly damaging |
Het |
| Ttn |
A |
T |
2: 76,750,086 (GRCm39) |
D3654E |
probably damaging |
Het |
| Ufd1 |
T |
G |
16: 18,639,832 (GRCm39) |
V112G |
probably damaging |
Het |
| Usp9y |
A |
T |
Y: 1,391,284 (GRCm39) |
Y629N |
possibly damaging |
Het |
| Vmn2r1 |
A |
G |
3: 63,989,267 (GRCm39) |
I69V |
probably benign |
Het |
| Zfp180 |
A |
T |
7: 23,805,246 (GRCm39) |
Y555F |
probably damaging |
Het |
| Zfp438 |
T |
C |
18: 5,214,403 (GRCm39) |
N185S |
probably benign |
Het |
| Zfp445 |
C |
T |
9: 122,686,215 (GRCm39) |
V15I |
possibly damaging |
Het |
| Zfp462 |
A |
G |
4: 55,013,476 (GRCm39) |
E1814G |
probably benign |
Het |
|
| Other mutations in Ttc6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL03278:Ttc6
|
APN |
12 |
57,668,812 (GRCm39) |
missense |
probably damaging |
0.99 |
|
polonius
|
UTSW |
12 |
57,704,928 (GRCm39) |
splice site |
probably null |
|
|
tybalt
|
UTSW |
12 |
57,720,542 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02802:Ttc6
|
UTSW |
12 |
57,622,654 (GRCm39) |
missense |
probably benign |
0.14 |
|
PIT4802001:Ttc6
|
UTSW |
12 |
57,772,462 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0698:Ttc6
|
UTSW |
12 |
57,720,002 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0988:Ttc6
|
UTSW |
12 |
57,735,435 (GRCm39) |
splice site |
probably benign |
|
|
R1290:Ttc6
|
UTSW |
12 |
57,707,199 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1338:Ttc6
|
UTSW |
12 |
57,663,155 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1468:Ttc6
|
UTSW |
12 |
57,721,463 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R1468:Ttc6
|
UTSW |
12 |
57,721,463 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R1481:Ttc6
|
UTSW |
12 |
57,783,916 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1488:Ttc6
|
UTSW |
12 |
57,696,301 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1558:Ttc6
|
UTSW |
12 |
57,733,132 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1570:Ttc6
|
UTSW |
12 |
57,721,549 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1619:Ttc6
|
UTSW |
12 |
57,784,454 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1819:Ttc6
|
UTSW |
12 |
57,741,286 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1826:Ttc6
|
UTSW |
12 |
57,707,033 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1863:Ttc6
|
UTSW |
12 |
57,760,881 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1872:Ttc6
|
UTSW |
12 |
57,751,338 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1887:Ttc6
|
UTSW |
12 |
57,720,044 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1937:Ttc6
|
UTSW |
12 |
57,663,109 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2014:Ttc6
|
UTSW |
12 |
57,623,003 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2056:Ttc6
|
UTSW |
12 |
57,784,479 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2058:Ttc6
|
UTSW |
12 |
57,784,479 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2059:Ttc6
|
UTSW |
12 |
57,784,479 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2152:Ttc6
|
UTSW |
12 |
57,752,338 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2179:Ttc6
|
UTSW |
12 |
57,719,904 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R2275:Ttc6
|
UTSW |
12 |
57,749,084 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2432:Ttc6
|
UTSW |
12 |
57,668,821 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2474:Ttc6
|
UTSW |
12 |
57,622,713 (GRCm39) |
missense |
probably benign |
0.37 |
|
R2853:Ttc6
|
UTSW |
12 |
57,622,967 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3848:Ttc6
|
UTSW |
12 |
57,723,932 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3853:Ttc6
|
UTSW |
12 |
57,775,335 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R3950:Ttc6
|
UTSW |
12 |
57,696,292 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3953:Ttc6
|
UTSW |
12 |
57,744,238 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3954:Ttc6
|
UTSW |
12 |
57,744,238 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3955:Ttc6
|
UTSW |
12 |
57,744,238 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3957:Ttc6
|
UTSW |
12 |
57,744,238 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4135:Ttc6
|
UTSW |
12 |
57,679,581 (GRCm39) |
intron |
probably benign |
|
|
R4387:Ttc6
|
UTSW |
12 |
57,689,836 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4577:Ttc6
|
UTSW |
12 |
57,623,441 (GRCm39) |
missense |
probably benign |
0.22 |
|
R4779:Ttc6
|
UTSW |
12 |
57,776,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4803:Ttc6
|
UTSW |
12 |
57,775,291 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4871:Ttc6
|
UTSW |
12 |
57,749,142 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4898:Ttc6
|
UTSW |
12 |
57,707,026 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4930:Ttc6
|
UTSW |
12 |
57,720,609 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4946:Ttc6
|
UTSW |
12 |
57,689,926 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5257:Ttc6
|
UTSW |
12 |
57,749,061 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5303:Ttc6
|
UTSW |
12 |
57,622,606 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5385:Ttc6
|
UTSW |
12 |
57,689,821 (GRCm39) |
splice site |
probably null |
|
|
R5402:Ttc6
|
UTSW |
12 |
57,783,817 (GRCm39) |
nonsense |
probably null |
|
|
R5428:Ttc6
|
UTSW |
12 |
57,736,620 (GRCm39) |
missense |
probably null |
0.98 |
|
R5436:Ttc6
|
UTSW |
12 |
57,721,380 (GRCm39) |
splice site |
probably null |
|
|
R5646:Ttc6
|
UTSW |
12 |
57,622,805 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5697:Ttc6
|
UTSW |
12 |
57,724,000 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5792:Ttc6
|
UTSW |
12 |
57,719,990 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5808:Ttc6
|
UTSW |
12 |
57,664,397 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R5842:Ttc6
|
UTSW |
12 |
57,783,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5935:Ttc6
|
UTSW |
12 |
57,720,590 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6144:Ttc6
|
UTSW |
12 |
57,719,886 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6155:Ttc6
|
UTSW |
12 |
57,784,402 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6283:Ttc6
|
UTSW |
12 |
57,749,048 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6371:Ttc6
|
UTSW |
12 |
57,775,249 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6715:Ttc6
|
UTSW |
12 |
57,721,556 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6738:Ttc6
|
UTSW |
12 |
57,735,426 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6795:Ttc6
|
UTSW |
12 |
57,751,199 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6959:Ttc6
|
UTSW |
12 |
57,704,928 (GRCm39) |
splice site |
probably null |
|
|
R7053:Ttc6
|
UTSW |
12 |
57,707,318 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7125:Ttc6
|
UTSW |
12 |
57,623,125 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7259:Ttc6
|
UTSW |
12 |
57,622,970 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7304:Ttc6
|
UTSW |
12 |
57,622,837 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7369:Ttc6
|
UTSW |
12 |
57,719,717 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7409:Ttc6
|
UTSW |
12 |
57,743,772 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7429:Ttc6
|
UTSW |
12 |
57,704,888 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7430:Ttc6
|
UTSW |
12 |
57,704,888 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7492:Ttc6
|
UTSW |
12 |
57,719,922 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7535:Ttc6
|
UTSW |
12 |
57,623,305 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7866:Ttc6
|
UTSW |
12 |
57,721,435 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7901:Ttc6
|
UTSW |
12 |
57,735,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7944:Ttc6
|
UTSW |
12 |
57,707,229 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7945:Ttc6
|
UTSW |
12 |
57,707,229 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7965:Ttc6
|
UTSW |
12 |
57,720,542 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8062:Ttc6
|
UTSW |
12 |
57,783,764 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8119:Ttc6
|
UTSW |
12 |
57,752,429 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8142:Ttc6
|
UTSW |
12 |
57,744,258 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8154:Ttc6
|
UTSW |
12 |
57,776,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Ttc6
|
UTSW |
12 |
57,720,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8335:Ttc6
|
UTSW |
12 |
57,707,077 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8343:Ttc6
|
UTSW |
12 |
57,707,282 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R8696:Ttc6
|
UTSW |
12 |
57,784,492 (GRCm39) |
missense |
probably benign |
0.20 |
|
R8875:Ttc6
|
UTSW |
12 |
57,776,194 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8875:Ttc6
|
UTSW |
12 |
57,751,199 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8876:Ttc6
|
UTSW |
12 |
57,784,489 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8924:Ttc6
|
UTSW |
12 |
57,697,790 (GRCm39) |
nonsense |
probably null |
|
|
R8944:Ttc6
|
UTSW |
12 |
57,689,826 (GRCm39) |
missense |
|
|
|
R8956:Ttc6
|
UTSW |
12 |
57,775,196 (GRCm39) |
nonsense |
probably null |
|
|
R9009:Ttc6
|
UTSW |
12 |
57,744,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9020:Ttc6
|
UTSW |
12 |
57,752,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9051:Ttc6
|
UTSW |
12 |
57,783,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9232:Ttc6
|
UTSW |
12 |
57,776,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9291:Ttc6
|
UTSW |
12 |
57,622,730 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9304:Ttc6
|
UTSW |
12 |
57,776,117 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9309:Ttc6
|
UTSW |
12 |
57,753,649 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9331:Ttc6
|
UTSW |
12 |
57,720,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9398:Ttc6
|
UTSW |
12 |
57,784,404 (GRCm39) |
nonsense |
probably null |
|
|
R9430:Ttc6
|
UTSW |
12 |
57,733,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9632:Ttc6
|
UTSW |
12 |
57,664,299 (GRCm39) |
missense |
probably benign |
|
|
R9688:Ttc6
|
UTSW |
12 |
57,720,602 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9732:Ttc6
|
UTSW |
12 |
57,775,335 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9740:Ttc6
|
UTSW |
12 |
57,736,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9749:Ttc6
|
UTSW |
12 |
57,701,559 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0021:Ttc6
|
UTSW |
12 |
57,622,904 (GRCm39) |
missense |
probably damaging |
0.96 |
|
X0058:Ttc6
|
UTSW |
12 |
57,753,637 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Ttc6
|
UTSW |
12 |
57,744,161 (GRCm39) |
missense |
probably benign |
0.08 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAAGACTGCAGTTTTGGAGAGG -3'
(R):5'- TGTGATGACTCTTAAGGGCTTTAC -3'
Sequencing Primer
(F):5'- GAGAGGGATTGTTGCCTTAAATTCAC -3'
(R):5'- ACTCTTAAGGGCTTTACAAGGG -3'
|
| Posted On |
2015-11-11 |
Incidental Mutation