Incidental Mutation 'R0403:Kif13a'
| ID |
35731 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kif13a
|
| Ensembl Gene |
ENSMUSG00000021375 |
| Gene Name |
kinesin family member 13A |
| Synonyms |
4930505I07Rik, N-3 kinesin |
| MMRRC Submission |
038608-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.264)
|
| Stock # |
R0403 (G1)
|
| Quality Score |
204 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
46902563-47083343 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 46944877 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 908
(V908A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000055304
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000056978]
[ENSMUST00000223881]
[ENSMUST00000225591]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000056978
AA Change: V908A
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000055304
Gene: ENSMUSG00000021375
AA Change: V908A
| Domain | Start | End | E-Value | Type |
|---|
|
KISc
|
3 |
360 |
2.69e-175 |
SMART |
|
low complexity region
|
368 |
381 |
N/A |
INTRINSIC |
|
low complexity region
|
391 |
406 |
N/A |
INTRINSIC |
|
FHA
|
469 |
519 |
7.16e-2 |
SMART |
|
coiled coil region
|
605 |
639 |
N/A |
INTRINSIC |
|
coiled coil region
|
664 |
704 |
N/A |
INTRINSIC |
|
Pfam:KIF1B
|
748 |
792 |
1.7e-19 |
PFAM |
|
low complexity region
|
840 |
854 |
N/A |
INTRINSIC |
|
low complexity region
|
903 |
915 |
N/A |
INTRINSIC |
|
Pfam:DUF3694
|
1003 |
1270 |
2.2e-39 |
PFAM |
|
low complexity region
|
1401 |
1412 |
N/A |
INTRINSIC |
|
low complexity region
|
1475 |
1492 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000223856
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000223881
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000224756
AA Change: V16A
PolyPhen 2
Score 0.247 (Sensitivity: 0.91; Specificity: 0.88)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000225591
AA Change: V845A
PolyPhen 2
Score 0.963 (Sensitivity: 0.78; Specificity: 0.95)
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000225904
|
| Meta Mutation Damage Score |
0.2033 |
| Coding Region Coverage |
- 1x: 98.0%
- 3x: 96.8%
- 10x: 93.2%
- 20x: 83.7%
|
| Validation Efficiency |
97% (110/113) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased anxiety. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ace |
A |
G |
11: 105,864,706 (GRCm39) |
|
probably null |
Het |
| Adgrg3 |
C |
T |
8: 95,763,550 (GRCm39) |
L284F |
probably benign |
Het |
| Alkbh8 |
T |
A |
9: 3,385,469 (GRCm39) |
V587E |
probably damaging |
Het |
| Ap4b1 |
T |
A |
3: 103,728,712 (GRCm39) |
M590K |
probably benign |
Het |
| Ap4b1 |
T |
A |
3: 103,726,155 (GRCm39) |
C244S |
probably damaging |
Het |
| Arhgap15 |
C |
T |
2: 43,953,778 (GRCm39) |
T168I |
probably damaging |
Het |
| Atp8b1 |
A |
G |
18: 64,673,381 (GRCm39) |
V997A |
probably damaging |
Het |
| Atrn |
G |
A |
2: 130,748,779 (GRCm39) |
C100Y |
probably damaging |
Het |
| Baiap2l2 |
C |
A |
15: 79,155,416 (GRCm39) |
A151S |
probably benign |
Het |
| Baz2b |
A |
T |
2: 59,799,721 (GRCm39) |
D199E |
possibly damaging |
Het |
| Bmal2 |
T |
A |
6: 146,724,153 (GRCm39) |
H348Q |
probably damaging |
Het |
| Cblb |
A |
G |
16: 51,972,989 (GRCm39) |
D440G |
probably benign |
Het |
| Cdon |
T |
C |
9: 35,384,796 (GRCm39) |
V694A |
probably benign |
Het |
| Cep250 |
A |
T |
2: 155,834,269 (GRCm39) |
R2065W |
probably damaging |
Het |
| Ces2b |
G |
T |
8: 105,560,577 (GRCm39) |
A131S |
probably damaging |
Het |
| Chrna9 |
A |
T |
5: 66,125,235 (GRCm39) |
T59S |
possibly damaging |
Het |
| Cog3 |
T |
A |
14: 75,979,767 (GRCm39) |
|
probably benign |
Het |
| Cpa1 |
G |
A |
6: 30,641,856 (GRCm39) |
V227I |
probably benign |
Het |
| Cyp3a25 |
A |
T |
5: 145,935,323 (GRCm39) |
C98S |
probably damaging |
Het |
| D8Ertd738e |
C |
T |
8: 84,976,230 (GRCm39) |
|
probably null |
Het |
| Ddx60 |
A |
G |
8: 62,447,575 (GRCm39) |
|
probably benign |
Het |
| Dhx16 |
T |
C |
17: 36,193,942 (GRCm39) |
|
probably null |
Het |
| Dnah9 |
T |
A |
11: 65,975,615 (GRCm39) |
Q1478L |
possibly damaging |
Het |
| Dock10 |
T |
C |
1: 80,501,787 (GRCm39) |
Y1434C |
possibly damaging |
Het |
| Enpp3 |
T |
A |
10: 24,680,334 (GRCm39) |
D325V |
probably damaging |
Het |
| Entpd6 |
C |
A |
2: 150,602,090 (GRCm39) |
T194K |
possibly damaging |
Het |
| Fat2 |
A |
T |
11: 55,161,175 (GRCm39) |
V3185E |
probably benign |
Het |
| Flrt1 |
A |
G |
19: 7,073,284 (GRCm39) |
L421P |
probably benign |
Het |
| Fmn2 |
A |
T |
1: 174,521,844 (GRCm39) |
Q1292L |
probably damaging |
Het |
| Fndc1 |
T |
C |
17: 7,972,555 (GRCm39) |
D1459G |
probably damaging |
Het |
| Fndc1 |
T |
C |
17: 7,994,420 (GRCm39) |
|
probably null |
Het |
| Fzr1 |
A |
G |
10: 81,205,202 (GRCm39) |
S265P |
possibly damaging |
Het |
| Gpr142 |
G |
A |
11: 114,696,855 (GRCm39) |
V134M |
probably damaging |
Het |
| Grid2ip |
G |
T |
5: 143,343,375 (GRCm39) |
V24L |
possibly damaging |
Het |
| Herc2 |
G |
A |
7: 55,809,165 (GRCm39) |
R2555H |
probably damaging |
Het |
| Hpdl |
A |
T |
4: 116,677,676 (GRCm39) |
Y262N |
possibly damaging |
Het |
| Htr3a |
A |
G |
9: 48,819,959 (GRCm39) |
V57A |
probably damaging |
Het |
| Igfbp7 |
T |
C |
5: 77,503,438 (GRCm39) |
I186V |
probably benign |
Het |
| Itga2b |
C |
T |
11: 102,358,152 (GRCm39) |
|
probably null |
Het |
| Itgae |
A |
C |
11: 73,014,009 (GRCm39) |
D736A |
possibly damaging |
Het |
| Itpkc |
T |
A |
7: 26,907,770 (GRCm39) |
M645L |
probably benign |
Het |
| Jchain |
T |
C |
5: 88,669,237 (GRCm39) |
R139G |
probably benign |
Het |
| Kif1b |
T |
A |
4: 149,266,424 (GRCm39) |
K389* |
probably null |
Het |
| Klhl12 |
T |
C |
1: 134,413,594 (GRCm39) |
Y360H |
possibly damaging |
Het |
| Knop1 |
G |
A |
7: 118,452,276 (GRCm39) |
R148W |
probably damaging |
Het |
| Lpar1 |
T |
A |
4: 58,487,191 (GRCm39) |
N27Y |
probably damaging |
Het |
| Lpar2 |
T |
A |
8: 70,276,802 (GRCm39) |
V197D |
probably damaging |
Het |
| Lrrc74a |
A |
G |
12: 86,787,753 (GRCm39) |
N128S |
probably damaging |
Het |
| Lum |
G |
T |
10: 97,407,905 (GRCm39) |
V337F |
probably benign |
Het |
| Mag |
T |
C |
7: 30,606,405 (GRCm39) |
D344G |
probably damaging |
Het |
| Maip1 |
G |
A |
1: 57,446,355 (GRCm39) |
A142T |
probably benign |
Het |
| Mlh3 |
A |
G |
12: 85,315,742 (GRCm39) |
V148A |
possibly damaging |
Het |
| Nav3 |
A |
G |
10: 109,602,964 (GRCm39) |
V1195A |
probably damaging |
Het |
| Ncor2 |
A |
G |
5: 125,110,401 (GRCm39) |
S868P |
possibly damaging |
Het |
| Nek1 |
A |
G |
8: 61,559,889 (GRCm39) |
E907G |
probably damaging |
Het |
| Nfam1 |
G |
A |
15: 82,900,580 (GRCm39) |
T134I |
probably benign |
Het |
| Nr0b2 |
T |
C |
4: 133,281,070 (GRCm39) |
V112A |
probably damaging |
Het |
| Nrp1 |
A |
G |
8: 129,184,450 (GRCm39) |
N365S |
probably damaging |
Het |
| Nrsn2 |
T |
C |
2: 152,211,710 (GRCm39) |
Y107C |
probably damaging |
Het |
| Ntng1 |
G |
A |
3: 109,841,927 (GRCm39) |
A282V |
probably damaging |
Het |
| Nxf1 |
T |
C |
19: 8,742,392 (GRCm39) |
I337T |
probably damaging |
Het |
| Obscn |
C |
T |
11: 58,967,366 (GRCm39) |
G479D |
probably damaging |
Het |
| Oprd1 |
T |
A |
4: 131,841,079 (GRCm39) |
D293V |
probably benign |
Het |
| Or13a17 |
T |
C |
7: 140,271,222 (GRCm39) |
S135P |
possibly damaging |
Het |
| P3h2 |
T |
G |
16: 25,788,700 (GRCm39) |
N586H |
possibly damaging |
Het |
| Pcid2 |
T |
C |
8: 13,135,367 (GRCm39) |
Y214C |
probably damaging |
Het |
| Pkd1l3 |
C |
G |
8: 110,350,281 (GRCm39) |
D375E |
possibly damaging |
Het |
| Pkd1l3 |
G |
A |
8: 110,350,295 (GRCm39) |
S380N |
probably benign |
Het |
| Ppic |
C |
A |
18: 53,544,143 (GRCm39) |
G81W |
probably damaging |
Het |
| Ppp2r1a |
C |
A |
17: 21,177,303 (GRCm39) |
P246T |
probably damaging |
Het |
| Ppp4r4 |
T |
G |
12: 103,550,361 (GRCm39) |
S46A |
probably benign |
Het |
| Pramel31 |
A |
G |
4: 144,089,216 (GRCm39) |
N178S |
probably benign |
Het |
| Prkce |
A |
G |
17: 86,476,081 (GRCm39) |
T21A |
probably damaging |
Het |
| Prkg2 |
T |
C |
5: 99,142,504 (GRCm39) |
E210G |
possibly damaging |
Het |
| Prss35 |
A |
G |
9: 86,638,090 (GRCm39) |
M287V |
probably damaging |
Het |
| Psd |
G |
A |
19: 46,309,411 (GRCm39) |
|
probably benign |
Het |
| Ptch2 |
A |
T |
4: 116,968,036 (GRCm39) |
K843* |
probably null |
Het |
| Rab44 |
C |
A |
17: 29,364,235 (GRCm39) |
T603K |
probably damaging |
Het |
| Rasal3 |
T |
A |
17: 32,611,764 (GRCm39) |
|
probably null |
Het |
| Rbbp6 |
A |
G |
7: 122,591,519 (GRCm39) |
T526A |
probably damaging |
Het |
| Ros1 |
A |
T |
10: 52,019,534 (GRCm39) |
|
probably benign |
Het |
| Sec24b |
T |
A |
3: 129,783,325 (GRCm39) |
L1104F |
possibly damaging |
Het |
| Sec24b |
A |
G |
3: 129,793,183 (GRCm39) |
S685P |
probably damaging |
Het |
| Sema6a |
G |
A |
18: 47,423,112 (GRCm39) |
|
probably null |
Het |
| Setmar |
A |
T |
6: 108,052,923 (GRCm39) |
H139L |
probably benign |
Het |
| Slc28a2b |
T |
C |
2: 122,352,335 (GRCm39) |
L364S |
probably damaging |
Het |
| Slc4a7 |
T |
C |
14: 14,766,808 (GRCm38) |
V710A |
probably benign |
Het |
| Smarcc1 |
T |
A |
9: 110,066,876 (GRCm39) |
|
probably null |
Het |
| Smchd1 |
G |
A |
17: 71,701,897 (GRCm39) |
L1032F |
probably damaging |
Het |
| Speg |
T |
C |
1: 75,407,428 (GRCm39) |
|
probably benign |
Het |
| Tasor2 |
A |
T |
13: 3,632,052 (GRCm39) |
Y816* |
probably null |
Het |
| Tcea1 |
C |
G |
1: 4,959,726 (GRCm39) |
R134G |
probably benign |
Het |
| Tchhl1 |
C |
T |
3: 93,378,336 (GRCm39) |
Q347* |
probably null |
Het |
| Tecrl |
A |
T |
5: 83,502,605 (GRCm39) |
|
probably benign |
Het |
| Tepsin |
T |
C |
11: 119,984,508 (GRCm39) |
|
probably benign |
Het |
| Tmem40 |
G |
A |
6: 115,710,946 (GRCm39) |
|
probably benign |
Het |
| Tpr |
G |
A |
1: 150,283,165 (GRCm39) |
|
probably benign |
Het |
| Ttll12 |
A |
T |
15: 83,464,859 (GRCm39) |
|
probably benign |
Het |
| Ttn |
T |
A |
2: 76,739,952 (GRCm39) |
D3529V |
probably benign |
Het |
| Usp34 |
T |
A |
11: 23,283,838 (GRCm39) |
H177Q |
possibly damaging |
Het |
| Vsig10 |
T |
A |
5: 117,476,526 (GRCm39) |
S327T |
probably benign |
Het |
| Zbtb4 |
T |
A |
11: 69,668,465 (GRCm39) |
M396K |
probably damaging |
Het |
| Zfp352 |
C |
T |
4: 90,113,246 (GRCm39) |
T462I |
possibly damaging |
Het |
| Zfp385b |
T |
C |
2: 77,307,189 (GRCm39) |
M145V |
probably damaging |
Het |
| Zfp780b |
C |
A |
7: 27,671,114 (GRCm39) |
V65F |
possibly damaging |
Het |
|
| Other mutations in Kif13a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01084:Kif13a
|
APN |
13 |
46,904,110 (GRCm39) |
splice site |
probably benign |
|
|
IGL01433:Kif13a
|
APN |
13 |
46,926,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01528:Kif13a
|
APN |
13 |
47,018,313 (GRCm39) |
splice site |
probably benign |
|
|
IGL01536:Kif13a
|
APN |
13 |
46,905,765 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01620:Kif13a
|
APN |
13 |
47,018,296 (GRCm39) |
missense |
probably benign |
|
|
IGL02020:Kif13a
|
APN |
13 |
46,947,495 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02142:Kif13a
|
APN |
13 |
46,925,011 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02375:Kif13a
|
APN |
13 |
46,978,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02407:Kif13a
|
APN |
13 |
46,938,769 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02476:Kif13a
|
APN |
13 |
46,938,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03038:Kif13a
|
APN |
13 |
46,926,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03053:Kif13a
|
APN |
13 |
46,905,564 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03366:Kif13a
|
APN |
13 |
46,918,099 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0025:Kif13a
|
UTSW |
13 |
46,939,987 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0106:Kif13a
|
UTSW |
13 |
46,978,823 (GRCm39) |
splice site |
probably benign |
|
|
R0106:Kif13a
|
UTSW |
13 |
46,978,823 (GRCm39) |
splice site |
probably benign |
|
|
R0135:Kif13a
|
UTSW |
13 |
46,947,419 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0137:Kif13a
|
UTSW |
13 |
46,918,079 (GRCm39) |
missense |
probably benign |
0.38 |
|
R0243:Kif13a
|
UTSW |
13 |
46,944,827 (GRCm39) |
missense |
probably benign |
0.24 |
|
R0346:Kif13a
|
UTSW |
13 |
46,967,695 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0492:Kif13a
|
UTSW |
13 |
46,966,218 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0607:Kif13a
|
UTSW |
13 |
46,956,187 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0631:Kif13a
|
UTSW |
13 |
46,932,364 (GRCm39) |
unclassified |
probably benign |
|
|
R0654:Kif13a
|
UTSW |
13 |
46,966,218 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0697:Kif13a
|
UTSW |
13 |
47,001,813 (GRCm39) |
missense |
probably benign |
0.19 |
|
R0699:Kif13a
|
UTSW |
13 |
46,952,689 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0715:Kif13a
|
UTSW |
13 |
46,966,299 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0834:Kif13a
|
UTSW |
13 |
46,967,712 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0903:Kif13a
|
UTSW |
13 |
47,082,735 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1419:Kif13a
|
UTSW |
13 |
46,978,711 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1428:Kif13a
|
UTSW |
13 |
46,944,987 (GRCm39) |
splice site |
probably benign |
|
|
R1449:Kif13a
|
UTSW |
13 |
46,966,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1463:Kif13a
|
UTSW |
13 |
47,083,088 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1541:Kif13a
|
UTSW |
13 |
46,962,689 (GRCm39) |
missense |
probably benign |
|
|
R1579:Kif13a
|
UTSW |
13 |
46,906,332 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1582:Kif13a
|
UTSW |
13 |
46,947,398 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1644:Kif13a
|
UTSW |
13 |
46,947,398 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1752:Kif13a
|
UTSW |
13 |
46,951,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1755:Kif13a
|
UTSW |
13 |
46,927,154 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1755:Kif13a
|
UTSW |
13 |
46,906,089 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1858:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R1891:Kif13a
|
UTSW |
13 |
47,082,695 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1902:Kif13a
|
UTSW |
13 |
46,941,638 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1928:Kif13a
|
UTSW |
13 |
46,966,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1960:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R1961:Kif13a
|
UTSW |
13 |
47,018,314 (GRCm39) |
splice site |
probably benign |
|
|
R2016:Kif13a
|
UTSW |
13 |
46,964,275 (GRCm39) |
missense |
probably benign |
0.13 |
|
R2139:Kif13a
|
UTSW |
13 |
46,905,945 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2174:Kif13a
|
UTSW |
13 |
46,922,652 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2407:Kif13a
|
UTSW |
13 |
46,930,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2504:Kif13a
|
UTSW |
13 |
46,967,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3122:Kif13a
|
UTSW |
13 |
46,918,072 (GRCm39) |
splice site |
probably benign |
|
|
R3499:Kif13a
|
UTSW |
13 |
46,978,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3905:Kif13a
|
UTSW |
13 |
46,956,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4474:Kif13a
|
UTSW |
13 |
46,967,631 (GRCm39) |
splice site |
probably null |
|
|
R4771:Kif13a
|
UTSW |
13 |
46,978,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4838:Kif13a
|
UTSW |
13 |
46,980,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Kif13a
|
UTSW |
13 |
47,083,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4931:Kif13a
|
UTSW |
13 |
46,962,531 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4980:Kif13a
|
UTSW |
13 |
46,906,222 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R4992:Kif13a
|
UTSW |
13 |
46,930,639 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5047:Kif13a
|
UTSW |
13 |
46,941,561 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5054:Kif13a
|
UTSW |
13 |
46,956,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5141:Kif13a
|
UTSW |
13 |
46,906,197 (GRCm39) |
missense |
probably benign |
|
|
R5329:Kif13a
|
UTSW |
13 |
46,928,877 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5429:Kif13a
|
UTSW |
13 |
46,926,245 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5499:Kif13a
|
UTSW |
13 |
46,986,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5509:Kif13a
|
UTSW |
13 |
46,905,591 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5594:Kif13a
|
UTSW |
13 |
46,906,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5921:Kif13a
|
UTSW |
13 |
46,978,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5964:Kif13a
|
UTSW |
13 |
46,925,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6115:Kif13a
|
UTSW |
13 |
46,954,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6317:Kif13a
|
UTSW |
13 |
46,980,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6318:Kif13a
|
UTSW |
13 |
46,968,683 (GRCm39) |
splice site |
probably null |
|
|
R6393:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6394:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6395:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6735:Kif13a
|
UTSW |
13 |
46,906,222 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R7037:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7038:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7039:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7237:Kif13a
|
UTSW |
13 |
46,962,632 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7285:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7286:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7287:Kif13a
|
UTSW |
13 |
46,905,931 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7341:Kif13a
|
UTSW |
13 |
46,980,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7693:Kif13a
|
UTSW |
13 |
46,904,089 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7761:Kif13a
|
UTSW |
13 |
46,951,955 (GRCm39) |
missense |
probably benign |
|
|
R8098:Kif13a
|
UTSW |
13 |
46,968,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Kif13a
|
UTSW |
13 |
46,932,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8271:Kif13a
|
UTSW |
13 |
46,906,057 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8806:Kif13a
|
UTSW |
13 |
46,914,813 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8871:Kif13a
|
UTSW |
13 |
46,984,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8877:Kif13a
|
UTSW |
13 |
46,954,921 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8906:Kif13a
|
UTSW |
13 |
46,927,154 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9028:Kif13a
|
UTSW |
13 |
46,951,841 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9058:Kif13a
|
UTSW |
13 |
46,944,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9062:Kif13a
|
UTSW |
13 |
46,941,536 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9070:Kif13a
|
UTSW |
13 |
46,905,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9083:Kif13a
|
UTSW |
13 |
46,966,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9250:Kif13a
|
UTSW |
13 |
46,928,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9328:Kif13a
|
UTSW |
13 |
46,951,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9360:Kif13a
|
UTSW |
13 |
46,962,472 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9369:Kif13a
|
UTSW |
13 |
46,940,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9589:Kif13a
|
UTSW |
13 |
46,956,020 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9749:Kif13a
|
UTSW |
13 |
46,914,227 (GRCm39) |
missense |
probably damaging |
0.96 |
|
X0013:Kif13a
|
UTSW |
13 |
47,082,746 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAGACCGTGCCCAATTCCACTG -3'
(R):5'- GGCTGTCCTGGTATTGATCCCCTG -3'
Sequencing Primer
(F):5'- AGCTGACAGTGGCTCTGTG -3'
(R):5'- CCCCTCTTAGAGATGACTGAACTATG -3'
|
| Posted On |
2013-05-09 |
Incidental Mutation