Incidental Mutation 'R4751:Clca3a1'
| ID |
357565 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Clca3a1
|
| Ensembl Gene |
ENSMUSG00000056025 |
| Gene Name |
chloride channel accessory 3A1 |
| Synonyms |
Clca1 |
| MMRRC Submission |
041970-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.060)
|
| Stock # |
R4751 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
144435438-144466738 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 144710609 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Isoleucine
at position 865
(F865I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000029919
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029919]
|
| AlphaFold |
Q9QX15 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000029919
AA Change: F865I
PolyPhen 2
Score 0.894 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000029919
Gene: ENSMUSG00000028255
AA Change: F865I
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
low complexity region
|
285 |
297 |
N/A |
INTRINSIC |
|
VWA
|
305 |
478 |
5.05e-19 |
SMART |
|
Blast:FN3
|
753 |
852 |
2e-28 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000195901
|
| Meta Mutation Damage Score |
0.1284 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.4%
|
| Validation Efficiency |
95% (124/131) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 115 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9130023H24Rik |
A |
T |
7: 127,836,258 (GRCm39) |
C112S |
probably benign |
Het |
| Abca13 |
G |
A |
11: 9,227,973 (GRCm39) |
|
probably null |
Het |
| Abca14 |
A |
G |
7: 119,911,400 (GRCm39) |
E1328G |
probably benign |
Het |
| Abca9 |
T |
A |
11: 110,021,396 (GRCm39) |
I1105F |
probably benign |
Het |
| Abr |
T |
C |
11: 76,347,434 (GRCm39) |
N396D |
possibly damaging |
Het |
| Aftph |
A |
C |
11: 20,677,074 (GRCm39) |
C178W |
probably damaging |
Het |
| Akr1c14 |
T |
C |
13: 4,115,338 (GRCm39) |
F89S |
possibly damaging |
Het |
| Ank3 |
C |
T |
10: 69,822,036 (GRCm39) |
A1518V |
probably benign |
Het |
| Arfgap2 |
T |
G |
2: 91,097,713 (GRCm39) |
S143R |
probably benign |
Het |
| Aspdh |
T |
A |
7: 44,116,629 (GRCm39) |
C107* |
probably null |
Het |
| Asphd2 |
C |
A |
5: 112,539,612 (GRCm39) |
G74W |
probably damaging |
Het |
| AU040320 |
G |
A |
4: 126,748,259 (GRCm39) |
|
probably null |
Het |
| B3glct |
T |
A |
5: 149,648,867 (GRCm39) |
|
probably null |
Het |
| Bcl9l |
A |
G |
9: 44,418,100 (GRCm39) |
K646R |
probably damaging |
Het |
| Brat1 |
T |
G |
5: 140,704,051 (GRCm39) |
L768R |
probably damaging |
Het |
| Btbd18 |
T |
A |
2: 84,498,265 (GRCm39) |
Y634* |
probably null |
Het |
| Bub1 |
T |
A |
2: 127,665,858 (GRCm39) |
|
probably benign |
Het |
| Carns1 |
A |
T |
19: 4,216,417 (GRCm39) |
D588E |
probably damaging |
Het |
| Cast |
T |
C |
13: 74,894,166 (GRCm39) |
K141E |
probably damaging |
Het |
| Cd109 |
CATTTATTTATTTATTTATTTATTTATTTATTTAT |
CATTTATTTATTTATTTATTTATTTATTTATTTATTTAT |
9: 78,619,782 (GRCm39) |
|
probably benign |
Het |
| Chsy3 |
T |
C |
18: 59,308,872 (GRCm39) |
S42P |
possibly damaging |
Het |
| Clec4f |
T |
A |
6: 83,622,264 (GRCm39) |
M526L |
possibly damaging |
Het |
| Clnk |
T |
C |
5: 38,878,256 (GRCm39) |
E301G |
probably benign |
Het |
| Colgalt2 |
T |
A |
1: 152,365,627 (GRCm39) |
I309N |
probably benign |
Het |
| Cyp2e1 |
A |
T |
7: 140,354,629 (GRCm39) |
K326* |
probably null |
Het |
| Dagla |
T |
A |
19: 10,227,758 (GRCm39) |
T717S |
probably benign |
Het |
| Dnajc11 |
G |
A |
4: 152,052,999 (GRCm39) |
R141H |
probably benign |
Het |
| Dst |
A |
G |
1: 34,230,965 (GRCm39) |
K2853E |
probably benign |
Het |
| Eif4g1 |
A |
G |
16: 20,505,265 (GRCm39) |
K1208E |
possibly damaging |
Het |
| Elane |
A |
G |
10: 79,722,625 (GRCm39) |
R48G |
probably benign |
Het |
| Fbxo30 |
T |
A |
10: 11,165,939 (GRCm39) |
N220K |
probably benign |
Het |
| Fbxo33 |
A |
T |
12: 59,247,714 (GRCm39) |
|
probably benign |
Het |
| Fetub |
G |
A |
16: 22,756,645 (GRCm39) |
V169I |
probably benign |
Het |
| Gpx6 |
A |
C |
13: 21,501,234 (GRCm39) |
Q107H |
probably damaging |
Het |
| H2bc18 |
A |
T |
3: 96,176,467 (GRCm39) |
|
probably benign |
Het |
| Homer3 |
A |
T |
8: 70,738,084 (GRCm39) |
I19F |
probably damaging |
Het |
| Hspa4 |
C |
T |
11: 53,175,026 (GRCm39) |
V144I |
probably benign |
Het |
| Icos |
C |
T |
1: 61,032,876 (GRCm39) |
S25L |
probably benign |
Het |
| Ifna4 |
A |
G |
4: 88,760,185 (GRCm39) |
T30A |
probably benign |
Het |
| Ino80b |
C |
T |
6: 83,101,731 (GRCm39) |
G46D |
probably damaging |
Het |
| Kpna2 |
T |
G |
11: 106,883,490 (GRCm39) |
I100L |
possibly damaging |
Het |
| Krt71 |
C |
T |
15: 101,643,901 (GRCm39) |
G446R |
probably damaging |
Het |
| Krtap31-2 |
A |
G |
11: 99,827,402 (GRCm39) |
N78S |
possibly damaging |
Het |
| Lman1 |
A |
G |
18: 66,131,505 (GRCm39) |
S132P |
probably benign |
Het |
| Lmna |
T |
C |
3: 88,393,840 (GRCm39) |
Q246R |
possibly damaging |
Het |
| Lrp10 |
T |
A |
14: 54,706,049 (GRCm39) |
V413E |
probably damaging |
Het |
| Macf1 |
A |
C |
4: 123,365,443 (GRCm39) |
I1541S |
probably benign |
Het |
| Med24 |
A |
G |
11: 98,597,258 (GRCm39) |
L874P |
probably damaging |
Het |
| Mgll |
T |
A |
6: 88,702,093 (GRCm39) |
|
probably benign |
Het |
| Mrpl37 |
A |
T |
4: 106,914,672 (GRCm39) |
L364Q |
probably damaging |
Het |
| Mrpl47 |
C |
T |
3: 32,782,590 (GRCm39) |
R209H |
probably benign |
Het |
| Muc5ac |
T |
C |
7: 141,371,338 (GRCm39) |
F3285L |
probably benign |
Het |
| Mylk |
A |
G |
16: 34,699,539 (GRCm39) |
R301G |
probably benign |
Het |
| Nacad |
A |
G |
11: 6,555,726 (GRCm39) |
L8P |
unknown |
Het |
| Ncf1 |
T |
A |
5: 134,258,399 (GRCm39) |
H8L |
probably damaging |
Het |
| Ncoa3 |
T |
A |
2: 165,911,823 (GRCm39) |
M1383K |
possibly damaging |
Het |
| Necab2 |
C |
T |
8: 120,194,337 (GRCm39) |
S271L |
probably benign |
Het |
| Nme8 |
A |
T |
13: 19,859,808 (GRCm39) |
|
probably null |
Het |
| Nsrp1 |
T |
G |
11: 76,967,545 (GRCm39) |
T16P |
possibly damaging |
Het |
| Obox3 |
A |
T |
7: 15,359,617 (GRCm39) |
|
probably null |
Het |
| Or1l8 |
T |
C |
2: 36,817,595 (GRCm39) |
H177R |
probably damaging |
Het |
| Or4c108 |
A |
G |
2: 88,803,477 (GRCm39) |
C253R |
probably damaging |
Het |
| Or4c15 |
T |
A |
2: 88,760,258 (GRCm39) |
I134F |
probably damaging |
Het |
| Or4d6 |
T |
A |
19: 12,086,541 (GRCm39) |
Y123F |
probably damaging |
Het |
| Or52n2b |
A |
T |
7: 104,565,617 (GRCm39) |
Y295* |
probably null |
Het |
| Or6b2 |
C |
A |
1: 92,407,705 (GRCm39) |
A213S |
probably benign |
Het |
| Osbpl3 |
C |
G |
6: 50,277,977 (GRCm39) |
E790Q |
possibly damaging |
Het |
| Osmr |
A |
T |
15: 6,872,333 (GRCm39) |
W254R |
probably damaging |
Het |
| Otoa |
T |
C |
7: 120,732,147 (GRCm39) |
|
probably benign |
Het |
| Pagr1a |
A |
T |
7: 126,614,551 (GRCm39) |
L218H |
probably damaging |
Het |
| Pcdha11 |
G |
A |
18: 37,139,997 (GRCm39) |
G542D |
probably damaging |
Het |
| Pck2 |
T |
A |
14: 55,780,018 (GRCm39) |
I54N |
probably damaging |
Het |
| Ppif |
T |
C |
14: 25,699,923 (GRCm39) |
V173A |
probably damaging |
Het |
| Ptgs2 |
T |
A |
1: 149,979,771 (GRCm39) |
L292H |
probably damaging |
Het |
| Ptpru |
A |
G |
4: 131,529,897 (GRCm39) |
S604P |
probably damaging |
Het |
| Qrfpr |
T |
C |
3: 36,236,771 (GRCm39) |
H210R |
possibly damaging |
Het |
| Rasgrf1 |
A |
G |
9: 89,792,171 (GRCm39) |
T41A |
probably damaging |
Het |
| Rasgrf1 |
A |
G |
9: 89,894,919 (GRCm39) |
H1113R |
probably damaging |
Het |
| Rhoc |
T |
A |
3: 104,699,963 (GRCm39) |
I80N |
probably damaging |
Het |
| Riok3 |
A |
G |
18: 12,287,040 (GRCm39) |
N472S |
probably benign |
Het |
| Rnf213 |
A |
G |
11: 119,336,571 (GRCm39) |
Y3314C |
probably benign |
Het |
| Shank2 |
C |
T |
7: 143,963,205 (GRCm39) |
T264I |
probably damaging |
Het |
| Shroom3 |
G |
T |
5: 93,090,945 (GRCm39) |
V1151F |
probably damaging |
Het |
| Sipa1l1 |
A |
G |
12: 82,387,968 (GRCm39) |
I65V |
probably benign |
Het |
| Slc22a19 |
T |
C |
19: 7,668,510 (GRCm39) |
K291R |
possibly damaging |
Het |
| Slc22a20 |
T |
C |
19: 6,030,488 (GRCm39) |
I315V |
probably benign |
Het |
| Slc44a1 |
A |
T |
4: 53,560,973 (GRCm39) |
D563V |
probably damaging |
Het |
| Smchd1 |
A |
T |
17: 71,698,463 (GRCm39) |
H1104Q |
probably benign |
Het |
| Spcs2 |
A |
T |
7: 99,493,976 (GRCm39) |
|
probably null |
Het |
| Speer1e |
T |
A |
5: 11,236,458 (GRCm39) |
Y138N |
probably damaging |
Het |
| Sptb |
T |
C |
12: 76,673,884 (GRCm39) |
E301G |
probably benign |
Het |
| Stum |
T |
C |
1: 180,270,234 (GRCm39) |
D86G |
probably damaging |
Het |
| Sufu |
A |
T |
19: 46,472,088 (GRCm39) |
D449V |
probably benign |
Het |
| Sun5 |
T |
C |
2: 153,707,936 (GRCm39) |
|
probably null |
Het |
| Tbc1d15 |
T |
A |
10: 115,038,492 (GRCm39) |
I574F |
probably damaging |
Het |
| Tert |
G |
A |
13: 73,776,182 (GRCm39) |
S311N |
possibly damaging |
Het |
| Tiparp |
T |
C |
3: 65,460,225 (GRCm39) |
Y507H |
probably damaging |
Het |
| Tnk2 |
T |
C |
16: 32,498,675 (GRCm39) |
C158R |
probably damaging |
Het |
| Tpgs1 |
T |
C |
10: 79,511,454 (GRCm39) |
S199P |
possibly damaging |
Het |
| Trdmt1 |
G |
T |
2: 13,549,464 (GRCm39) |
|
probably benign |
Het |
| Trp53bp1 |
T |
A |
2: 121,058,290 (GRCm39) |
D944V |
probably damaging |
Het |
| Tsc1 |
T |
A |
2: 28,569,093 (GRCm39) |
I720N |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,539,949 (GRCm39) |
T34346A |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,727,925 (GRCm39) |
|
probably benign |
Het |
| Uba7 |
T |
A |
9: 107,857,004 (GRCm39) |
C686S |
possibly damaging |
Het |
| Ush2a |
T |
A |
1: 188,582,284 (GRCm39) |
F3782L |
probably damaging |
Het |
| Vars2 |
A |
T |
17: 35,970,235 (GRCm39) |
H745Q |
possibly damaging |
Het |
| Vgf |
T |
A |
5: 137,061,255 (GRCm39) |
D472E |
probably damaging |
Het |
| Vmn2r15 |
T |
C |
5: 109,434,620 (GRCm39) |
M695V |
probably benign |
Het |
| Vps41 |
A |
T |
13: 18,995,792 (GRCm39) |
D208V |
probably damaging |
Het |
| Vta1 |
C |
T |
10: 14,531,560 (GRCm39) |
A272T |
probably benign |
Het |
| Wnk4 |
G |
A |
11: 101,167,188 (GRCm39) |
|
probably benign |
Het |
| Zfp507 |
T |
C |
7: 35,493,807 (GRCm39) |
K412R |
probably damaging |
Het |
| Zfp768 |
A |
G |
7: 126,943,934 (GRCm39) |
F65L |
possibly damaging |
Het |
| Zfp956 |
T |
C |
6: 47,940,510 (GRCm39) |
S290P |
probably benign |
Het |
|
| Other mutations in Clca3a1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00664:Clca3a1
|
APN |
3 |
144,733,660 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00768:Clca3a1
|
APN |
3 |
144,461,012 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00862:Clca3a1
|
APN |
3 |
144,730,332 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL00895:Clca3a1
|
APN |
3 |
144,730,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00969:Clca3a1
|
APN |
3 |
144,714,719 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL01331:Clca3a1
|
APN |
3 |
144,453,273 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01398:Clca3a1
|
APN |
3 |
144,722,512 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL01447:Clca3a1
|
APN |
3 |
144,713,539 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01455:Clca3a1
|
APN |
3 |
144,713,539 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01457:Clca3a1
|
APN |
3 |
144,713,539 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01458:Clca3a1
|
APN |
3 |
144,713,539 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01462:Clca3a1
|
APN |
3 |
144,713,539 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01473:Clca3a1
|
APN |
3 |
144,713,539 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01488:Clca3a1
|
APN |
3 |
144,713,539 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01490:Clca3a1
|
APN |
3 |
144,713,539 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01632:Clca3a1
|
APN |
3 |
144,733,202 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01895:Clca3a1
|
APN |
3 |
144,453,333 (GRCm39) |
nonsense |
probably null |
|
|
IGL01896:Clca3a1
|
APN |
3 |
144,721,438 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL01940:Clca3a1
|
APN |
3 |
144,452,737 (GRCm39) |
missense |
probably benign |
0.25 |
|
IGL02162:Clca3a1
|
APN |
3 |
144,460,564 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02200:Clca3a1
|
APN |
3 |
144,457,690 (GRCm39) |
splice site |
probably benign |
|
|
IGL02411:Clca3a1
|
APN |
3 |
144,733,763 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL03093:Clca3a1
|
APN |
3 |
144,453,262 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03156:Clca3a1
|
APN |
3 |
144,719,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Lucha
|
UTSW |
3 |
144,455,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0256:Clca3a1
|
UTSW |
3 |
144,436,640 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0472:Clca3a1
|
UTSW |
3 |
144,733,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0513:Clca3a1
|
UTSW |
3 |
144,466,323 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0543:Clca3a1
|
UTSW |
3 |
144,454,155 (GRCm39) |
splice site |
probably benign |
|
|
R0571:Clca3a1
|
UTSW |
3 |
144,713,550 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0585:Clca3a1
|
UTSW |
3 |
144,738,386 (GRCm39) |
missense |
probably benign |
0.16 |
|
R0586:Clca3a1
|
UTSW |
3 |
144,738,350 (GRCm39) |
missense |
probably benign |
0.45 |
|
R0791:Clca3a1
|
UTSW |
3 |
144,710,615 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1187:Clca3a1
|
UTSW |
3 |
144,715,504 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1522:Clca3a1
|
UTSW |
3 |
144,460,932 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1713:Clca3a1
|
UTSW |
3 |
144,730,307 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1739:Clca3a1
|
UTSW |
3 |
144,713,539 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1744:Clca3a1
|
UTSW |
3 |
144,452,596 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1873:Clca3a1
|
UTSW |
3 |
144,452,590 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2079:Clca3a1
|
UTSW |
3 |
144,713,534 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R2129:Clca3a1
|
UTSW |
3 |
144,722,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2178:Clca3a1
|
UTSW |
3 |
144,711,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2234:Clca3a1
|
UTSW |
3 |
144,714,829 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2235:Clca3a1
|
UTSW |
3 |
144,714,829 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2238:Clca3a1
|
UTSW |
3 |
144,457,766 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2240:Clca3a1
|
UTSW |
3 |
144,714,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2278:Clca3a1
|
UTSW |
3 |
144,463,785 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2516:Clca3a1
|
UTSW |
3 |
144,443,619 (GRCm39) |
splice site |
probably null |
|
|
R3737:Clca3a1
|
UTSW |
3 |
144,436,482 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3751:Clca3a1
|
UTSW |
3 |
144,724,424 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3974:Clca3a1
|
UTSW |
3 |
144,738,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3975:Clca3a1
|
UTSW |
3 |
144,738,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3981:Clca3a1
|
UTSW |
3 |
144,461,070 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3982:Clca3a1
|
UTSW |
3 |
144,461,070 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3983:Clca3a1
|
UTSW |
3 |
144,461,070 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4038:Clca3a1
|
UTSW |
3 |
144,460,994 (GRCm39) |
missense |
probably benign |
0.35 |
|
R4382:Clca3a1
|
UTSW |
3 |
144,466,483 (GRCm39) |
start codon destroyed |
probably benign |
0.08 |
|
R4409:Clca3a1
|
UTSW |
3 |
144,711,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4543:Clca3a1
|
UTSW |
3 |
144,452,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4586:Clca3a1
|
UTSW |
3 |
144,722,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4766:Clca3a1
|
UTSW |
3 |
144,455,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4894:Clca3a1
|
UTSW |
3 |
144,719,662 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4899:Clca3a1
|
UTSW |
3 |
144,443,722 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4909:Clca3a1
|
UTSW |
3 |
144,730,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4916:Clca3a1
|
UTSW |
3 |
144,721,605 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4941:Clca3a1
|
UTSW |
3 |
144,721,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Clca3a1
|
UTSW |
3 |
144,710,524 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5044:Clca3a1
|
UTSW |
3 |
144,713,689 (GRCm39) |
splice site |
probably null |
|
|
R5090:Clca3a1
|
UTSW |
3 |
144,443,633 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5091:Clca3a1
|
UTSW |
3 |
144,436,483 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5205:Clca3a1
|
UTSW |
3 |
144,452,545 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R5248:Clca3a1
|
UTSW |
3 |
144,442,897 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R5354:Clca3a1
|
UTSW |
3 |
144,442,766 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5451:Clca3a1
|
UTSW |
3 |
144,733,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5618:Clca3a1
|
UTSW |
3 |
144,710,738 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5724:Clca3a1
|
UTSW |
3 |
144,714,833 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5871:Clca3a1
|
UTSW |
3 |
144,460,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5898:Clca3a1
|
UTSW |
3 |
144,722,522 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5907:Clca3a1
|
UTSW |
3 |
144,455,403 (GRCm39) |
intron |
probably benign |
|
|
R5976:Clca3a1
|
UTSW |
3 |
144,452,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6190:Clca3a1
|
UTSW |
3 |
144,463,821 (GRCm39) |
missense |
probably benign |
0.40 |
|
R6193:Clca3a1
|
UTSW |
3 |
144,464,993 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6238:Clca3a1
|
UTSW |
3 |
144,714,716 (GRCm39) |
missense |
probably benign |
0.09 |
|
R6263:Clca3a1
|
UTSW |
3 |
144,455,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6299:Clca3a1
|
UTSW |
3 |
144,464,275 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6327:Clca3a1
|
UTSW |
3 |
144,436,558 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6497:Clca3a1
|
UTSW |
3 |
144,465,020 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6542:Clca3a1
|
UTSW |
3 |
144,465,021 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6547:Clca3a1
|
UTSW |
3 |
144,442,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6590:Clca3a1
|
UTSW |
3 |
144,719,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6591:Clca3a1
|
UTSW |
3 |
144,719,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6592:Clca3a1
|
UTSW |
3 |
144,719,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6690:Clca3a1
|
UTSW |
3 |
144,719,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6691:Clca3a1
|
UTSW |
3 |
144,719,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6729:Clca3a1
|
UTSW |
3 |
144,711,727 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6759:Clca3a1
|
UTSW |
3 |
144,455,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6805:Clca3a1
|
UTSW |
3 |
144,724,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7032:Clca3a1
|
UTSW |
3 |
144,453,329 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7063:Clca3a1
|
UTSW |
3 |
144,460,967 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7106:Clca3a1
|
UTSW |
3 |
144,733,190 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7121:Clca3a1
|
UTSW |
3 |
144,717,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7127:Clca3a1
|
UTSW |
3 |
144,711,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7139:Clca3a1
|
UTSW |
3 |
144,461,063 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R7212:Clca3a1
|
UTSW |
3 |
144,711,727 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7444:Clca3a1
|
UTSW |
3 |
144,733,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7446:Clca3a1
|
UTSW |
3 |
144,733,188 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7535:Clca3a1
|
UTSW |
3 |
144,724,328 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7638:Clca3a1
|
UTSW |
3 |
144,457,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7663:Clca3a1
|
UTSW |
3 |
144,442,797 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7792:Clca3a1
|
UTSW |
3 |
144,455,492 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7798:Clca3a1
|
UTSW |
3 |
144,463,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7892:Clca3a1
|
UTSW |
3 |
144,436,579 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8096:Clca3a1
|
UTSW |
3 |
144,455,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8305:Clca3a1
|
UTSW |
3 |
144,464,927 (GRCm39) |
splice site |
probably benign |
|
|
R8416:Clca3a1
|
UTSW |
3 |
144,460,914 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8437:Clca3a1
|
UTSW |
3 |
144,710,822 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8446:Clca3a1
|
UTSW |
3 |
144,454,248 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8474:Clca3a1
|
UTSW |
3 |
144,710,792 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R8496:Clca3a1
|
UTSW |
3 |
144,453,182 (GRCm39) |
makesense |
probably null |
|
|
R8766:Clca3a1
|
UTSW |
3 |
144,714,939 (GRCm39) |
splice site |
probably benign |
|
|
R8884:Clca3a1
|
UTSW |
3 |
144,719,757 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9014:Clca3a1
|
UTSW |
3 |
144,442,731 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9049:Clca3a1
|
UTSW |
3 |
144,733,143 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9128:Clca3a1
|
UTSW |
3 |
144,463,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9306:Clca3a1
|
UTSW |
3 |
144,730,339 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9601:Clca3a1
|
UTSW |
3 |
144,453,310 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9623:Clca3a1
|
UTSW |
3 |
144,719,698 (GRCm39) |
missense |
probably benign |
0.03 |
|
X0020:Clca3a1
|
UTSW |
3 |
144,738,421 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
Z1088:Clca3a1
|
UTSW |
3 |
144,452,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Clca3a1
|
UTSW |
3 |
144,719,682 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCTCCAGTGAAAGGAATGACTGG -3'
(R):5'- GTATCGTTGATCTCAGGGACCAC -3'
Sequencing Primer
(F):5'- AGTGAAAGGAATGACTGGTTGATTTC -3'
(R):5'- GTTGATCTCAGGGACCACTTCAAC -3'
|
| Posted On |
2015-11-11 |
Incidental Mutation