Incidental Mutation 'R4754:Tmprss15'
| ID |
357853 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tmprss15
|
| Ensembl Gene |
ENSMUSG00000022857 |
| Gene Name |
transmembrane protease, serine 15 |
| Synonyms |
Prss7, enterokinase, enteropeptidase, A130097D21Rik |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4754 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
78749896-78887985 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 78851012 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 294
(S294T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000052034
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000023566]
[ENSMUST00000060402]
|
| AlphaFold |
P97435 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000023566
AA Change: S309T
PolyPhen 2
Score 0.969 (Sensitivity: 0.77; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000023566
Gene: ENSMUSG00000022857
AA Change: S309T
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
21 |
43 |
N/A |
INTRINSIC |
|
SEA
|
52 |
172 |
1.62e-22 |
SMART |
|
LDLa
|
228 |
268 |
1.74e-4 |
SMART |
|
CUB
|
270 |
379 |
1.54e-11 |
SMART |
|
MAM
|
387 |
549 |
7.33e-54 |
SMART |
|
low complexity region
|
551 |
567 |
N/A |
INTRINSIC |
|
CUB
|
569 |
679 |
1.72e-32 |
SMART |
|
LDLa
|
687 |
724 |
7.32e-12 |
SMART |
|
SR
|
723 |
813 |
3.12e-5 |
SMART |
|
Tryp_SPc
|
829 |
1064 |
1.48e-95 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000060402
AA Change: S294T
PolyPhen 2
Score 0.980 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000052034
Gene: ENSMUSG00000022857
AA Change: S294T
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
21 |
43 |
N/A |
INTRINSIC |
|
SEA
|
52 |
172 |
1.62e-22 |
SMART |
|
LDLa
|
213 |
253 |
1.74e-4 |
SMART |
|
CUB
|
255 |
364 |
1.54e-11 |
SMART |
|
MAM
|
372 |
534 |
7.33e-54 |
SMART |
|
low complexity region
|
536 |
552 |
N/A |
INTRINSIC |
|
CUB
|
554 |
664 |
1.72e-32 |
SMART |
|
LDLa
|
672 |
709 |
7.32e-12 |
SMART |
|
SR
|
708 |
798 |
3.12e-5 |
SMART |
|
Tryp_SPc
|
814 |
1049 |
1.48e-95 |
SMART |
|
| Meta Mutation Damage Score |
0.1768 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 94.7%
|
| Validation Efficiency |
98% (107/109) |
| MGI Phenotype |
FUNCTION: This gene encodes an enzyme that proteolytically activates the pancreatic proenzyme trypsinogen, converting it into trypsin. The encoded protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A130010J15Rik |
A |
G |
1: 192,856,837 (GRCm39) |
Y63C |
probably damaging |
Het |
| Abcb4 |
C |
A |
5: 8,960,717 (GRCm39) |
F266L |
probably damaging |
Het |
| Adam8 |
A |
T |
7: 139,564,693 (GRCm39) |
I681N |
possibly damaging |
Het |
| Adgrf3 |
T |
A |
5: 30,402,615 (GRCm39) |
|
probably null |
Het |
| Ang2 |
A |
G |
14: 51,432,974 (GRCm39) |
V136A |
probably damaging |
Het |
| Ankar |
C |
T |
1: 72,737,853 (GRCm39) |
G110R |
probably damaging |
Het |
| Ap3b1 |
T |
C |
13: 94,540,468 (GRCm39) |
L130P |
probably damaging |
Het |
| Apc2 |
T |
G |
10: 80,150,192 (GRCm39) |
W1749G |
probably benign |
Het |
| Asb2 |
T |
C |
12: 103,290,096 (GRCm39) |
N565S |
possibly damaging |
Het |
| B3gnt7 |
C |
A |
1: 86,233,279 (GRCm39) |
T58K |
probably benign |
Het |
| Bltp1 |
C |
T |
3: 37,076,615 (GRCm39) |
Q3663* |
probably null |
Het |
| Brpf1 |
T |
A |
6: 113,297,408 (GRCm39) |
N876K |
possibly damaging |
Het |
| Ccdc157 |
T |
C |
11: 4,098,994 (GRCm39) |
I69V |
possibly damaging |
Het |
| Cd109 |
CATTTATTTATTTATTTATTTATTTATTTATTTAT |
CATTTATTTATTTATTTATTTATTTATTTATTTATTTAT |
9: 78,619,782 (GRCm39) |
|
probably benign |
Het |
| Cdh20 |
A |
T |
1: 104,912,410 (GRCm39) |
I555F |
probably damaging |
Het |
| Cfap73 |
T |
C |
5: 120,767,729 (GRCm39) |
D274G |
probably damaging |
Het |
| Chd5 |
T |
A |
4: 152,462,203 (GRCm39) |
I1310N |
probably damaging |
Het |
| Ckap2 |
T |
A |
8: 22,658,911 (GRCm39) |
I611F |
possibly damaging |
Het |
| Cpeb2 |
A |
G |
5: 43,443,200 (GRCm39) |
I964V |
possibly damaging |
Het |
| Ctbp2 |
C |
A |
7: 132,625,287 (GRCm39) |
|
probably null |
Het |
| Dhrs2 |
A |
T |
14: 55,476,205 (GRCm39) |
I142F |
probably damaging |
Het |
| Dnah5 |
T |
A |
15: 28,421,101 (GRCm39) |
|
probably null |
Het |
| Dst |
T |
C |
1: 34,251,390 (GRCm39) |
S1822P |
probably damaging |
Het |
| Ect2 |
T |
C |
3: 27,181,112 (GRCm39) |
K581E |
probably damaging |
Het |
| Edem1 |
C |
T |
6: 108,818,658 (GRCm39) |
T222M |
probably damaging |
Het |
| Eif2ak1 |
A |
G |
5: 143,838,621 (GRCm39) |
M592V |
probably damaging |
Het |
| Endou |
T |
G |
15: 97,624,420 (GRCm39) |
D49A |
probably damaging |
Het |
| Ensa |
A |
G |
3: 95,529,865 (GRCm39) |
|
probably benign |
Het |
| Evc2 |
G |
T |
5: 37,544,375 (GRCm39) |
R708L |
probably damaging |
Het |
| Fam120b |
T |
A |
17: 15,643,224 (GRCm39) |
C668S |
probably damaging |
Het |
| Fam135a |
A |
T |
1: 24,067,835 (GRCm39) |
C798* |
probably null |
Het |
| Fam135b |
T |
C |
15: 71,334,800 (GRCm39) |
D798G |
probably benign |
Het |
| Fshb |
A |
C |
2: 106,887,627 (GRCm39) |
*131E |
probably null |
Het |
| G3bp2 |
C |
T |
5: 92,202,768 (GRCm39) |
V441M |
possibly damaging |
Het |
| Galnt6 |
A |
T |
15: 100,597,105 (GRCm39) |
F354I |
probably damaging |
Het |
| Gm1123 |
C |
A |
9: 98,905,293 (GRCm39) |
|
probably null |
Het |
| Gm1123 |
A |
T |
9: 98,905,294 (GRCm39) |
|
probably null |
Het |
| Gm15130 |
T |
C |
2: 110,973,207 (GRCm39) |
N115S |
unknown |
Het |
| Gm7104 |
A |
G |
12: 88,252,765 (GRCm39) |
|
noncoding transcript |
Het |
| Gm9762 |
A |
T |
3: 78,873,728 (GRCm39) |
|
noncoding transcript |
Het |
| Grip2 |
T |
C |
6: 91,756,173 (GRCm39) |
T505A |
probably damaging |
Het |
| Grip2 |
A |
G |
6: 91,756,163 (GRCm39) |
V508A |
probably damaging |
Het |
| Haus4 |
A |
G |
14: 54,787,349 (GRCm39) |
|
probably null |
Het |
| Herc1 |
T |
A |
9: 66,408,488 (GRCm39) |
D4571E |
probably benign |
Het |
| Hnrnpk |
T |
A |
13: 58,546,950 (GRCm39) |
|
probably benign |
Het |
| Ica1l |
T |
C |
1: 60,067,321 (GRCm39) |
Y23C |
probably damaging |
Het |
| Kansl2-ps |
A |
G |
7: 72,322,881 (GRCm39) |
|
noncoding transcript |
Het |
| Kcnma1 |
T |
C |
14: 23,413,904 (GRCm39) |
D833G |
probably damaging |
Het |
| Kmt2e |
A |
T |
5: 23,687,439 (GRCm39) |
I430F |
possibly damaging |
Het |
| Lama2 |
C |
A |
10: 26,994,527 (GRCm39) |
R1794L |
possibly damaging |
Het |
| Mcpt1 |
T |
A |
14: 56,256,137 (GRCm39) |
F59I |
probably damaging |
Het |
| Mib2 |
G |
T |
4: 155,739,822 (GRCm39) |
T783K |
possibly damaging |
Het |
| Nlrp4g |
T |
C |
9: 124,349,788 (GRCm38) |
|
noncoding transcript |
Het |
| Nudt16l2 |
A |
T |
9: 105,021,592 (GRCm39) |
F151L |
probably benign |
Het |
| Obscn |
T |
C |
11: 58,926,869 (GRCm39) |
I6352V |
possibly damaging |
Het |
| Or2j6 |
C |
T |
7: 139,980,072 (GRCm39) |
A296T |
probably damaging |
Het |
| Or4a72 |
A |
T |
2: 89,405,391 (GRCm39) |
H226Q |
probably benign |
Het |
| Or4k1 |
T |
A |
14: 50,377,490 (GRCm39) |
N202I |
possibly damaging |
Het |
| Or4k1 |
T |
G |
14: 50,377,491 (GRCm39) |
N202H |
probably benign |
Het |
| Or52a5 |
T |
C |
7: 103,426,875 (GRCm39) |
I226V |
probably benign |
Het |
| Or5b125-ps1 |
T |
A |
19: 13,056,225 (GRCm39) |
|
noncoding transcript |
Het |
| Pcdh10 |
G |
A |
3: 45,335,072 (GRCm39) |
R462H |
probably damaging |
Het |
| Pcdhga12 |
C |
A |
18: 37,899,604 (GRCm39) |
N145K |
probably damaging |
Het |
| Pik3r6 |
T |
A |
11: 68,435,601 (GRCm39) |
L613Q |
probably damaging |
Het |
| Pknox2 |
T |
C |
9: 36,821,016 (GRCm39) |
D282G |
probably damaging |
Het |
| Plod2 |
T |
G |
9: 92,488,584 (GRCm39) |
Y624* |
probably null |
Het |
| Prkd3 |
C |
A |
17: 79,264,043 (GRCm39) |
V684F |
probably damaging |
Het |
| Ptpn1 |
T |
A |
2: 167,816,080 (GRCm39) |
V198D |
probably damaging |
Het |
| Ptpn12 |
G |
T |
5: 21,203,587 (GRCm39) |
P397Q |
probably benign |
Het |
| Rad1 |
C |
A |
15: 10,493,212 (GRCm39) |
|
probably benign |
Het |
| Rasl11a |
A |
G |
5: 146,783,825 (GRCm39) |
D90G |
probably benign |
Het |
| Rnf181 |
A |
G |
6: 72,337,543 (GRCm39) |
|
probably benign |
Het |
| Ryr3 |
T |
C |
2: 112,587,984 (GRCm39) |
I2652M |
possibly damaging |
Het |
| Siglecg |
C |
T |
7: 43,061,295 (GRCm39) |
|
probably benign |
Het |
| Slc22a3 |
T |
C |
17: 12,726,082 (GRCm39) |
S44G |
probably benign |
Het |
| Slc38a1 |
A |
T |
15: 96,474,663 (GRCm39) |
F463I |
probably damaging |
Het |
| Smg1 |
A |
T |
7: 117,755,954 (GRCm39) |
|
probably benign |
Het |
| Syk |
T |
C |
13: 52,766,295 (GRCm39) |
|
probably benign |
Het |
| Tasor |
A |
T |
14: 27,183,052 (GRCm39) |
I504L |
probably benign |
Het |
| Tbc1d5 |
T |
C |
17: 51,107,193 (GRCm39) |
I454M |
probably benign |
Het |
| Tmed6 |
C |
A |
8: 107,790,362 (GRCm39) |
D146Y |
probably damaging |
Het |
| Tmem132e |
A |
T |
11: 82,335,677 (GRCm39) |
K828* |
probably null |
Het |
| Trp53bp1 |
A |
G |
2: 121,038,360 (GRCm39) |
S1493P |
probably damaging |
Het |
| Tshb |
A |
T |
3: 102,685,491 (GRCm39) |
I46N |
probably damaging |
Het |
| Tspan11 |
T |
C |
6: 127,915,183 (GRCm39) |
V99A |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,545,905 (GRCm39) |
T24176A |
probably benign |
Het |
| Vmn1r8 |
T |
C |
6: 57,012,952 (GRCm39) |
M1T |
probably null |
Het |
| Vmn2r104 |
A |
T |
17: 20,261,030 (GRCm39) |
Y464* |
probably null |
Het |
| Vmn2r110 |
T |
C |
17: 20,816,458 (GRCm39) |
T22A |
probably benign |
Het |
| Vmn2r17 |
T |
A |
5: 109,600,715 (GRCm39) |
I671K |
probably damaging |
Het |
| Zbtb21 |
T |
C |
16: 97,752,466 (GRCm39) |
N606D |
probably damaging |
Het |
| Zfy2 |
A |
T |
Y: 2,121,477 (GRCm39) |
S139T |
probably benign |
Het |
| Zkscan17 |
G |
A |
11: 59,393,851 (GRCm39) |
R156* |
probably null |
Het |
| Zp2 |
A |
G |
7: 119,737,541 (GRCm39) |
V248A |
probably benign |
Het |
|
| Other mutations in Tmprss15 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00331:Tmprss15
|
APN |
16 |
78,782,882 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL00477:Tmprss15
|
APN |
16 |
78,818,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01583:Tmprss15
|
APN |
16 |
78,868,149 (GRCm39) |
missense |
probably benign |
|
|
IGL01896:Tmprss15
|
APN |
16 |
78,887,678 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL02052:Tmprss15
|
APN |
16 |
78,884,394 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02374:Tmprss15
|
APN |
16 |
78,832,056 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02505:Tmprss15
|
APN |
16 |
78,784,629 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02632:Tmprss15
|
APN |
16 |
78,782,790 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02674:Tmprss15
|
APN |
16 |
78,798,682 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
beached
|
UTSW |
16 |
78,821,736 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
Cellulite
|
UTSW |
16 |
78,754,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
lolling
|
UTSW |
16 |
78,800,298 (GRCm39) |
missense |
probably benign |
0.26 |
|
miniature
|
UTSW |
16 |
78,854,497 (GRCm39) |
critical splice donor site |
probably null |
|
|
PIT1430001:Tmprss15
|
UTSW |
16 |
78,821,640 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0106:Tmprss15
|
UTSW |
16 |
78,800,277 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0106:Tmprss15
|
UTSW |
16 |
78,800,277 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0195:Tmprss15
|
UTSW |
16 |
78,831,222 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0335:Tmprss15
|
UTSW |
16 |
78,821,630 (GRCm39) |
splice site |
probably benign |
|
|
R0514:Tmprss15
|
UTSW |
16 |
78,765,155 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0552:Tmprss15
|
UTSW |
16 |
78,821,637 (GRCm39) |
splice site |
probably null |
|
|
R0675:Tmprss15
|
UTSW |
16 |
78,782,838 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0739:Tmprss15
|
UTSW |
16 |
78,821,736 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1435:Tmprss15
|
UTSW |
16 |
78,818,342 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1446:Tmprss15
|
UTSW |
16 |
78,875,846 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1572:Tmprss15
|
UTSW |
16 |
78,887,717 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1708:Tmprss15
|
UTSW |
16 |
78,850,958 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1893:Tmprss15
|
UTSW |
16 |
78,868,306 (GRCm39) |
missense |
probably benign |
|
|
R2403:Tmprss15
|
UTSW |
16 |
78,854,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2866:Tmprss15
|
UTSW |
16 |
78,832,121 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2913:Tmprss15
|
UTSW |
16 |
78,759,078 (GRCm39) |
missense |
probably benign |
0.45 |
|
R2914:Tmprss15
|
UTSW |
16 |
78,759,078 (GRCm39) |
missense |
probably benign |
0.45 |
|
R3425:Tmprss15
|
UTSW |
16 |
78,800,321 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R3703:Tmprss15
|
UTSW |
16 |
78,851,030 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3916:Tmprss15
|
UTSW |
16 |
78,782,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3950:Tmprss15
|
UTSW |
16 |
78,870,074 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4332:Tmprss15
|
UTSW |
16 |
78,831,222 (GRCm39) |
missense |
probably benign |
0.15 |
|
R4392:Tmprss15
|
UTSW |
16 |
78,821,326 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4515:Tmprss15
|
UTSW |
16 |
78,754,244 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4619:Tmprss15
|
UTSW |
16 |
78,818,358 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4620:Tmprss15
|
UTSW |
16 |
78,818,358 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4853:Tmprss15
|
UTSW |
16 |
78,757,479 (GRCm39) |
missense |
probably benign |
|
|
R5159:Tmprss15
|
UTSW |
16 |
78,800,298 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5441:Tmprss15
|
UTSW |
16 |
78,868,335 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5824:Tmprss15
|
UTSW |
16 |
78,831,201 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5970:Tmprss15
|
UTSW |
16 |
78,854,547 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6224:Tmprss15
|
UTSW |
16 |
78,821,266 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6257:Tmprss15
|
UTSW |
16 |
78,769,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6313:Tmprss15
|
UTSW |
16 |
78,759,058 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6368:Tmprss15
|
UTSW |
16 |
78,802,945 (GRCm39) |
splice site |
probably null |
|
|
R6525:Tmprss15
|
UTSW |
16 |
78,800,266 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6587:Tmprss15
|
UTSW |
16 |
78,868,317 (GRCm39) |
missense |
probably benign |
|
|
R6894:Tmprss15
|
UTSW |
16 |
78,872,702 (GRCm39) |
nonsense |
probably null |
|
|
R7018:Tmprss15
|
UTSW |
16 |
78,821,741 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7180:Tmprss15
|
UTSW |
16 |
78,764,886 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7324:Tmprss15
|
UTSW |
16 |
78,758,907 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7337:Tmprss15
|
UTSW |
16 |
78,868,164 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7558:Tmprss15
|
UTSW |
16 |
78,800,302 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R7732:Tmprss15
|
UTSW |
16 |
78,800,308 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7792:Tmprss15
|
UTSW |
16 |
78,800,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7829:Tmprss15
|
UTSW |
16 |
78,784,538 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7998:Tmprss15
|
UTSW |
16 |
78,798,731 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R8009:Tmprss15
|
UTSW |
16 |
78,887,751 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8145:Tmprss15
|
UTSW |
16 |
78,757,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8183:Tmprss15
|
UTSW |
16 |
78,884,400 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8221:Tmprss15
|
UTSW |
16 |
78,821,223 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8294:Tmprss15
|
UTSW |
16 |
78,868,176 (GRCm39) |
missense |
probably benign |
|
|
R8537:Tmprss15
|
UTSW |
16 |
78,884,403 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8735:Tmprss15
|
UTSW |
16 |
78,798,702 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8858:Tmprss15
|
UTSW |
16 |
78,854,497 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8869:Tmprss15
|
UTSW |
16 |
78,750,834 (GRCm39) |
nonsense |
probably null |
|
|
R8884:Tmprss15
|
UTSW |
16 |
78,821,657 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9014:Tmprss15
|
UTSW |
16 |
78,872,691 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9075:Tmprss15
|
UTSW |
16 |
78,754,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9351:Tmprss15
|
UTSW |
16 |
78,832,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9393:Tmprss15
|
UTSW |
16 |
78,754,211 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9747:Tmprss15
|
UTSW |
16 |
78,884,400 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9767:Tmprss15
|
UTSW |
16 |
78,875,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9783:Tmprss15
|
UTSW |
16 |
78,887,890 (GRCm39) |
start gained |
probably benign |
|
|
RF005:Tmprss15
|
UTSW |
16 |
78,750,689 (GRCm39) |
makesense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACATTGAAAGAGAAACATTACCACT -3'
(R):5'- CCAAAAGCAGATGGTAAGACCTCT -3'
Sequencing Primer
(F):5'- TTACCACTCACCAAGCTTCC -3'
(R):5'- AGCAGTTCTCACAATGGTCTG -3'
|
| Posted On |
2015-11-11 |
Incidental Mutation