Incidental Mutation 'R4755:Thsd7b'
| ID |
357867 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Thsd7b
|
| Ensembl Gene |
ENSMUSG00000042581 |
| Gene Name |
thrombospondin, type I, domain containing 7B |
| Synonyms |
1700074E13Rik, D130067I03Rik |
| MMRRC Submission |
042033-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.114)
|
| Stock # |
R4755 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
129273302-130219278 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 130210264 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Asparagine
at position 1560
(Y1560N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000073220
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000073527]
|
| AlphaFold |
Q6P4U0 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000073527
AA Change: Y1560N
PolyPhen 2
Score 0.013 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000073220
Gene: ENSMUSG00000042581
AA Change: Y1560N
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
36 |
N/A |
INTRINSIC |
|
Blast:TSP1
|
43 |
98 |
5e-29 |
BLAST |
|
Blast:TSP1
|
122 |
177 |
9e-24 |
BLAST |
|
TSP1
|
182 |
233 |
2.47e-9 |
SMART |
|
TSP1
|
339 |
399 |
7e-9 |
SMART |
|
Blast:TSP1
|
402 |
482 |
2e-27 |
BLAST |
|
TSP1
|
487 |
543 |
2.12e-1 |
SMART |
|
TSP1
|
604 |
661 |
3.9e-7 |
SMART |
|
TSP1
|
664 |
735 |
2.73e-2 |
SMART |
|
TSP1
|
740 |
796 |
1.01e-5 |
SMART |
|
Blast:TSP1
|
799 |
869 |
6e-35 |
BLAST |
|
TSP1
|
874 |
922 |
9.68e-3 |
SMART |
|
TSP1
|
952 |
999 |
2.42e0 |
SMART |
|
TSP1
|
1004 |
1059 |
3.96e-8 |
SMART |
|
TSP1
|
1062 |
1126 |
1.73e0 |
SMART |
|
TSP1
|
1131 |
1182 |
6.05e-4 |
SMART |
|
TSP1
|
1185 |
1246 |
9.52e-1 |
SMART |
|
TSP1
|
1251 |
1303 |
3.21e-8 |
SMART |
|
TSP1
|
1304 |
1369 |
5.52e-1 |
SMART |
|
TSP1
|
1374 |
1432 |
3.92e-2 |
SMART |
|
transmembrane domain
|
1558 |
1580 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140834
|
| Meta Mutation Damage Score |
0.3964 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.7%
- 10x: 97.3%
- 20x: 95.3%
|
| Validation Efficiency |
96% (112/117) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 113 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930449A18Rik |
T |
A |
3: 59,825,859 (GRCm38) |
|
noncoding transcript |
Het |
| Accs |
T |
C |
2: 93,841,337 (GRCm38) |
E236G |
probably damaging |
Het |
| Agrn |
C |
T |
4: 156,173,522 (GRCm38) |
|
probably benign |
Het |
| Ahi1 |
A |
G |
10: 21,055,047 (GRCm38) |
I929V |
possibly damaging |
Het |
| Akap5 |
C |
A |
12: 76,327,807 (GRCm38) |
C4* |
probably null |
Het |
| Amotl2 |
A |
T |
9: 102,720,480 (GRCm38) |
H146L |
probably damaging |
Het |
| Ank1 |
A |
G |
8: 23,104,974 (GRCm38) |
N666S |
probably damaging |
Het |
| Atp10d |
A |
T |
5: 72,246,166 (GRCm38) |
T373S |
probably benign |
Het |
| Bpifb9b |
T |
A |
2: 154,319,694 (GRCm38) |
M582K |
probably benign |
Het |
| Brca2 |
T |
A |
5: 150,559,987 (GRCm38) |
|
probably null |
Het |
| C130079G13Rik |
C |
T |
3: 59,936,314 (GRCm38) |
A143V |
probably benign |
Het |
| C330021F23Rik |
A |
T |
8: 3,583,922 (GRCm38) |
S8C |
probably damaging |
Het |
| Ccdc149 |
A |
G |
5: 52,404,151 (GRCm38) |
V229A |
probably damaging |
Het |
| Cd109 |
CATTTATTTATTTATTTATTTATTTATTTATTTAT |
CATTTATTTATTTATTTATTTATTTATTTATTTATTTAT |
9: 78,712,500 (GRCm38) |
|
probably benign |
Het |
| Cdk5rap2 |
A |
G |
4: 70,238,425 (GRCm38) |
S1617P |
probably damaging |
Het |
| Cenpk |
A |
T |
13: 104,249,512 (GRCm38) |
H305L |
probably benign |
Het |
| Cenpk |
A |
T |
13: 104,230,871 (GRCm38) |
M37L |
probably benign |
Het |
| Ces5a |
C |
A |
8: 93,535,677 (GRCm38) |
A11S |
probably benign |
Het |
| Cfap65 |
T |
C |
1: 74,928,361 (GRCm38) |
E186G |
probably damaging |
Het |
| Cfh |
T |
A |
1: 140,088,808 (GRCm38) |
I593F |
probably damaging |
Het |
| Clstn2 |
C |
T |
9: 97,445,673 (GRCm38) |
V961I |
probably benign |
Het |
| Cog5 |
T |
A |
12: 31,869,406 (GRCm38) |
|
probably null |
Het |
| Col4a4 |
T |
C |
1: 82,541,174 (GRCm38) |
D100G |
unknown |
Het |
| Cyp3a41a |
T |
C |
5: 145,715,506 (GRCm38) |
D61G |
probably damaging |
Het |
| Dnah10 |
A |
G |
5: 124,747,745 (GRCm38) |
N655S |
probably benign |
Het |
| Dnaic1 |
C |
G |
4: 41,610,269 (GRCm38) |
T295R |
probably damaging |
Het |
| Dnajc6 |
C |
T |
4: 101,550,799 (GRCm38) |
A44V |
probably damaging |
Het |
| Eif4enif1 |
A |
T |
11: 3,244,016 (GRCm38) |
D960V |
probably damaging |
Het |
| Fam167b |
C |
T |
4: 129,578,342 (GRCm38) |
G12R |
probably damaging |
Het |
| Fam20b |
A |
T |
1: 156,687,496 (GRCm38) |
Y266* |
probably null |
Het |
| Fer1l6 |
T |
A |
15: 58,640,211 (GRCm38) |
V1509D |
probably benign |
Het |
| Fhad1 |
A |
T |
4: 141,928,483 (GRCm38) |
I105N |
probably damaging |
Het |
| Fmo2 |
T |
C |
1: 162,888,805 (GRCm38) |
D71G |
probably damaging |
Het |
| Folr2 |
T |
C |
7: 101,843,799 (GRCm38) |
T6A |
possibly damaging |
Het |
| Fry |
A |
C |
5: 150,398,254 (GRCm38) |
E1018A |
probably damaging |
Het |
| Gas2l2 |
A |
G |
11: 83,429,367 (GRCm38) |
I21T |
probably damaging |
Het |
| Gfra1 |
T |
C |
19: 58,453,244 (GRCm38) |
Y85C |
probably damaging |
Het |
| Gm9117 |
T |
C |
3: 93,938,786 (GRCm38) |
|
probably null |
Het |
| Gpld1 |
T |
A |
13: 24,979,692 (GRCm38) |
Y44* |
probably null |
Het |
| Gpld1 |
A |
T |
13: 24,979,688 (GRCm38) |
Y43F |
probably benign |
Het |
| Grid2 |
A |
G |
6: 63,908,988 (GRCm38) |
T123A |
probably benign |
Het |
| Grina |
T |
C |
15: 76,249,242 (GRCm38) |
L305P |
probably damaging |
Het |
| Gucy1a1 |
G |
A |
3: 82,094,795 (GRCm38) |
A659V |
probably benign |
Het |
| H2-T10 |
T |
A |
17: 36,118,945 (GRCm38) |
K319* |
probably null |
Het |
| Hey2 |
A |
T |
10: 30,834,304 (GRCm38) |
V151E |
probably benign |
Het |
| Ighv1-69 |
G |
A |
12: 115,623,558 (GRCm38) |
T13I |
probably benign |
Het |
| Il1rap |
C |
A |
16: 26,722,782 (GRCm38) |
A591E |
probably benign |
Het |
| Ildr1 |
T |
C |
16: 36,722,021 (GRCm38) |
L261P |
probably benign |
Het |
| Jak1 |
A |
G |
4: 101,174,157 (GRCm38) |
Y463H |
probably damaging |
Het |
| Lrp1b |
T |
C |
2: 41,269,273 (GRCm38) |
I1666V |
probably benign |
Het |
| Lrp1b |
T |
A |
2: 41,471,016 (GRCm38) |
T592S |
probably benign |
Het |
| Lrrc36 |
A |
G |
8: 105,452,144 (GRCm38) |
T445A |
possibly damaging |
Het |
| Ly9 |
G |
A |
1: 171,607,238 (GRCm38) |
S29F |
probably damaging |
Het |
| Mapk7 |
A |
C |
11: 61,490,843 (GRCm38) |
C32W |
probably damaging |
Het |
| March10 |
C |
T |
11: 105,364,476 (GRCm38) |
|
probably benign |
Het |
| Mier2 |
A |
T |
10: 79,549,197 (GRCm38) |
M119K |
probably damaging |
Het |
| Mpv17 |
A |
T |
5: 31,145,982 (GRCm38) |
C59* |
probably null |
Het |
| Mrpl27 |
G |
A |
11: 94,653,833 (GRCm38) |
|
probably benign |
Het |
| Myo18b |
G |
A |
5: 112,874,474 (GRCm38) |
Q351* |
probably null |
Het |
| Myo1a |
A |
G |
10: 127,715,688 (GRCm38) |
I704M |
probably damaging |
Het |
| Nadsyn1 |
A |
G |
7: 143,806,913 (GRCm38) |
C373R |
probably damaging |
Het |
| Nckipsd |
C |
A |
9: 108,814,739 (GRCm38) |
A513E |
probably benign |
Het |
| Neb |
T |
C |
2: 52,220,209 (GRCm38) |
D209G |
probably damaging |
Het |
| Nkapl |
T |
A |
13: 21,468,287 (GRCm38) |
Q52L |
unknown |
Het |
| Nptx2 |
G |
A |
5: 144,546,440 (GRCm38) |
S126N |
probably benign |
Het |
| Olfr13 |
G |
A |
6: 43,174,043 (GRCm38) |
S19N |
probably benign |
Het |
| Olfr653 |
T |
A |
7: 104,580,061 (GRCm38) |
Y138* |
probably null |
Het |
| Olfr829 |
A |
T |
9: 18,857,180 (GRCm38) |
H185L |
probably benign |
Het |
| Olfr917 |
A |
G |
9: 38,665,832 (GRCm38) |
V4A |
probably benign |
Het |
| Pclo |
A |
T |
5: 14,714,348 (GRCm38) |
R4278S |
unknown |
Het |
| Pcnx |
T |
G |
12: 81,950,294 (GRCm38) |
L988R |
probably damaging |
Het |
| Prl2c5 |
C |
A |
13: 13,189,385 (GRCm38) |
N75K |
probably benign |
Het |
| Prpf19 |
T |
G |
19: 10,897,790 (GRCm38) |
|
probably benign |
Het |
| Ralgapa1 |
A |
G |
12: 55,712,748 (GRCm38) |
S997P |
probably damaging |
Het |
| Rangap1 |
T |
C |
15: 81,712,917 (GRCm38) |
T226A |
probably benign |
Het |
| Rimklb |
G |
A |
6: 122,456,406 (GRCm38) |
L262F |
probably damaging |
Het |
| Rnf169 |
A |
G |
7: 99,925,723 (GRCm38) |
M555T |
probably benign |
Het |
| Rp1l1 |
A |
T |
14: 64,030,070 (GRCm38) |
D1035V |
probably benign |
Het |
| Scd2 |
T |
A |
19: 44,301,352 (GRCm38) |
L262Q |
probably damaging |
Het |
| Scgb2b12 |
T |
A |
7: 32,325,531 (GRCm38) |
M84L |
probably benign |
Het |
| Shroom3 |
G |
T |
5: 92,943,086 (GRCm38) |
V1151F |
probably damaging |
Het |
| Sipa1l1 |
G |
A |
12: 82,372,386 (GRCm38) |
V613I |
possibly damaging |
Het |
| Slc25a23 |
T |
A |
17: 57,052,794 (GRCm38) |
D67V |
possibly damaging |
Het |
| Slc25a39 |
C |
T |
11: 102,406,666 (GRCm38) |
|
probably benign |
Het |
| Slc4a10 |
T |
A |
2: 62,296,988 (GRCm38) |
F895Y |
probably damaging |
Het |
| Slc5a4a |
A |
C |
10: 76,186,564 (GRCm38) |
K578Q |
probably benign |
Het |
| Slc6a13 |
G |
A |
6: 121,325,049 (GRCm38) |
G197S |
probably damaging |
Het |
| Smarca2 |
A |
T |
19: 26,654,483 (GRCm38) |
E566V |
possibly damaging |
Het |
| Sorbs3 |
A |
T |
14: 70,184,099 (GRCm38) |
N594K |
probably benign |
Het |
| Spata22 |
A |
T |
11: 73,345,756 (GRCm38) |
D296V |
probably damaging |
Het |
| Sphk2 |
G |
A |
7: 45,713,634 (GRCm38) |
A11V |
possibly damaging |
Het |
| Spp1 |
A |
T |
5: 104,435,215 (GRCm38) |
|
probably benign |
Het |
| Strn3 |
T |
A |
12: 51,610,216 (GRCm38) |
I760L |
possibly damaging |
Het |
| Syk |
A |
T |
13: 52,641,986 (GRCm38) |
Y539F |
probably benign |
Het |
| Tmod2 |
C |
A |
9: 75,597,212 (GRCm38) |
E42* |
probably null |
Het |
| Tom1l1 |
T |
C |
11: 90,685,116 (GRCm38) |
E30G |
probably damaging |
Het |
| Trav10 |
G |
A |
14: 53,506,061 (GRCm38) |
A40T |
probably benign |
Het |
| Trav14-2 |
G |
A |
14: 53,640,780 (GRCm38) |
|
probably benign |
Het |
| Tril |
T |
A |
6: 53,818,464 (GRCm38) |
E591V |
probably damaging |
Het |
| Trp53bp1 |
T |
A |
2: 121,228,606 (GRCm38) |
R179* |
probably null |
Het |
| Tspoap1 |
A |
T |
11: 87,771,663 (GRCm38) |
D562V |
possibly damaging |
Het |
| Usp44 |
A |
T |
10: 93,846,906 (GRCm38) |
H406L |
probably damaging |
Het |
| Vangl1 |
A |
G |
3: 102,158,292 (GRCm38) |
I509T |
probably benign |
Het |
| Vax2 |
T |
G |
6: 83,711,397 (GRCm38) |
L34W |
probably damaging |
Het |
| Vmn1r55 |
A |
T |
7: 5,147,026 (GRCm38) |
C133S |
probably damaging |
Het |
| Vmn2r8 |
T |
A |
5: 108,801,700 (GRCm38) |
D427V |
probably benign |
Het |
| Vwde |
A |
G |
6: 13,205,852 (GRCm38) |
I232T |
possibly damaging |
Het |
| Wnk1 |
C |
A |
6: 119,963,470 (GRCm38) |
A769S |
probably damaging |
Het |
| Xpo4 |
A |
C |
14: 57,618,181 (GRCm38) |
S264A |
probably benign |
Het |
| Zfp330 |
A |
T |
8: 82,769,386 (GRCm38) |
C75* |
probably null |
Het |
| Zfp526 |
T |
A |
7: 25,225,639 (GRCm38) |
L441Q |
probably benign |
Het |
| Zfp607b |
T |
G |
7: 27,703,505 (GRCm38) |
L462R |
probably damaging |
Het |
| Zfp719 |
T |
A |
7: 43,590,793 (GRCm38) |
F602I |
probably damaging |
Het |
|
| Other mutations in Thsd7b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00417:Thsd7b
|
APN |
1 |
129,595,834 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00850:Thsd7b
|
APN |
1 |
130,165,077 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL00987:Thsd7b
|
APN |
1 |
129,613,279 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01068:Thsd7b
|
APN |
1 |
129,596,146 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01091:Thsd7b
|
APN |
1 |
129,776,334 (GRCm38) |
missense |
probably benign |
0.29 |
|
IGL01535:Thsd7b
|
APN |
1 |
129,678,217 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
IGL01560:Thsd7b
|
APN |
1 |
130,218,181 (GRCm38) |
utr 3 prime |
probably benign |
|
|
IGL01701:Thsd7b
|
APN |
1 |
129,430,928 (GRCm38) |
missense |
probably benign |
0.07 |
|
IGL01775:Thsd7b
|
APN |
1 |
129,628,939 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02077:Thsd7b
|
APN |
1 |
129,816,682 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02338:Thsd7b
|
APN |
1 |
129,595,771 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02340:Thsd7b
|
APN |
1 |
130,159,632 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02404:Thsd7b
|
APN |
1 |
129,613,151 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02519:Thsd7b
|
APN |
1 |
129,613,195 (GRCm38) |
missense |
probably benign |
0.22 |
|
IGL02543:Thsd7b
|
APN |
1 |
130,165,103 (GRCm38) |
missense |
probably benign |
0.03 |
|
IGL02740:Thsd7b
|
APN |
1 |
129,613,127 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02793:Thsd7b
|
APN |
1 |
129,951,393 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02875:Thsd7b
|
APN |
1 |
129,951,393 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02986:Thsd7b
|
APN |
1 |
129,915,615 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL03108:Thsd7b
|
APN |
1 |
130,210,276 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03114:Thsd7b
|
APN |
1 |
130,188,551 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03195:Thsd7b
|
APN |
1 |
129,628,909 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03291:Thsd7b
|
APN |
1 |
129,760,355 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL03397:Thsd7b
|
APN |
1 |
129,596,164 (GRCm38) |
missense |
probably benign |
0.17 |
|
IGL03399:Thsd7b
|
APN |
1 |
129,628,885 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0184:Thsd7b
|
UTSW |
1 |
129,430,964 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0277:Thsd7b
|
UTSW |
1 |
130,195,263 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0526:Thsd7b
|
UTSW |
1 |
129,951,392 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0633:Thsd7b
|
UTSW |
1 |
130,188,526 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R0746:Thsd7b
|
UTSW |
1 |
130,188,531 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0784:Thsd7b
|
UTSW |
1 |
129,595,359 (GRCm38) |
splice site |
probably benign |
|
|
R1158:Thsd7b
|
UTSW |
1 |
130,189,935 (GRCm38) |
splice site |
probably null |
|
|
R1267:Thsd7b
|
UTSW |
1 |
129,628,840 (GRCm38) |
splice site |
probably null |
|
|
R1375:Thsd7b
|
UTSW |
1 |
130,159,686 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1565:Thsd7b
|
UTSW |
1 |
129,596,041 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R1728:Thsd7b
|
UTSW |
1 |
129,678,183 (GRCm38) |
missense |
probably benign |
|
|
R1728:Thsd7b
|
UTSW |
1 |
129,667,937 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1728:Thsd7b
|
UTSW |
1 |
129,628,891 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1728:Thsd7b
|
UTSW |
1 |
130,116,631 (GRCm38) |
missense |
probably benign |
|
|
R1729:Thsd7b
|
UTSW |
1 |
129,678,183 (GRCm38) |
missense |
probably benign |
|
|
R1729:Thsd7b
|
UTSW |
1 |
129,667,937 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1729:Thsd7b
|
UTSW |
1 |
129,628,891 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1729:Thsd7b
|
UTSW |
1 |
130,116,631 (GRCm38) |
missense |
probably benign |
|
|
R1730:Thsd7b
|
UTSW |
1 |
129,678,183 (GRCm38) |
missense |
probably benign |
|
|
R1730:Thsd7b
|
UTSW |
1 |
129,667,937 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1730:Thsd7b
|
UTSW |
1 |
129,628,891 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1730:Thsd7b
|
UTSW |
1 |
130,116,631 (GRCm38) |
missense |
probably benign |
|
|
R1739:Thsd7b
|
UTSW |
1 |
129,667,937 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1739:Thsd7b
|
UTSW |
1 |
129,628,891 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1739:Thsd7b
|
UTSW |
1 |
130,116,631 (GRCm38) |
missense |
probably benign |
|
|
R1739:Thsd7b
|
UTSW |
1 |
129,678,183 (GRCm38) |
missense |
probably benign |
|
|
R1762:Thsd7b
|
UTSW |
1 |
129,667,937 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1762:Thsd7b
|
UTSW |
1 |
129,628,891 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1762:Thsd7b
|
UTSW |
1 |
130,116,631 (GRCm38) |
missense |
probably benign |
|
|
R1762:Thsd7b
|
UTSW |
1 |
130,103,076 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R1762:Thsd7b
|
UTSW |
1 |
129,678,183 (GRCm38) |
missense |
probably benign |
|
|
R1783:Thsd7b
|
UTSW |
1 |
129,678,183 (GRCm38) |
missense |
probably benign |
|
|
R1783:Thsd7b
|
UTSW |
1 |
129,667,937 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1783:Thsd7b
|
UTSW |
1 |
129,628,891 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1783:Thsd7b
|
UTSW |
1 |
130,116,631 (GRCm38) |
missense |
probably benign |
|
|
R1784:Thsd7b
|
UTSW |
1 |
129,667,937 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1784:Thsd7b
|
UTSW |
1 |
129,628,891 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1784:Thsd7b
|
UTSW |
1 |
130,116,631 (GRCm38) |
missense |
probably benign |
|
|
R1784:Thsd7b
|
UTSW |
1 |
129,678,183 (GRCm38) |
missense |
probably benign |
|
|
R1785:Thsd7b
|
UTSW |
1 |
129,678,183 (GRCm38) |
missense |
probably benign |
|
|
R1785:Thsd7b
|
UTSW |
1 |
129,667,937 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1785:Thsd7b
|
UTSW |
1 |
129,628,891 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1785:Thsd7b
|
UTSW |
1 |
130,116,631 (GRCm38) |
missense |
probably benign |
|
|
R1812:Thsd7b
|
UTSW |
1 |
129,758,610 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1846:Thsd7b
|
UTSW |
1 |
129,613,256 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1908:Thsd7b
|
UTSW |
1 |
129,678,109 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1996:Thsd7b
|
UTSW |
1 |
129,758,451 (GRCm38) |
nonsense |
probably null |
|
|
R2199:Thsd7b
|
UTSW |
1 |
130,218,158 (GRCm38) |
missense |
probably benign |
0.04 |
|
R2483:Thsd7b
|
UTSW |
1 |
130,103,072 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2919:Thsd7b
|
UTSW |
1 |
130,189,850 (GRCm38) |
splice site |
probably benign |
|
|
R2935:Thsd7b
|
UTSW |
1 |
129,678,087 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R3113:Thsd7b
|
UTSW |
1 |
130,049,862 (GRCm38) |
missense |
probably benign |
0.23 |
|
R3236:Thsd7b
|
UTSW |
1 |
130,218,118 (GRCm38) |
nonsense |
probably null |
|
|
R3745:Thsd7b
|
UTSW |
1 |
129,678,241 (GRCm38) |
missense |
probably benign |
0.04 |
|
R3877:Thsd7b
|
UTSW |
1 |
130,190,182 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R3880:Thsd7b
|
UTSW |
1 |
129,595,370 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4110:Thsd7b
|
UTSW |
1 |
130,116,619 (GRCm38) |
missense |
probably benign |
0.18 |
|
R4112:Thsd7b
|
UTSW |
1 |
130,116,619 (GRCm38) |
missense |
probably benign |
0.18 |
|
R4255:Thsd7b
|
UTSW |
1 |
129,760,287 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R4621:Thsd7b
|
UTSW |
1 |
129,430,915 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
R4703:Thsd7b
|
UTSW |
1 |
130,049,909 (GRCm38) |
intron |
probably benign |
|
|
R4732:Thsd7b
|
UTSW |
1 |
129,613,186 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4733:Thsd7b
|
UTSW |
1 |
129,613,186 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4805:Thsd7b
|
UTSW |
1 |
130,188,539 (GRCm38) |
missense |
probably benign |
0.04 |
|
R4840:Thsd7b
|
UTSW |
1 |
129,595,844 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4879:Thsd7b
|
UTSW |
1 |
130,188,499 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
R4936:Thsd7b
|
UTSW |
1 |
129,678,145 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4972:Thsd7b
|
UTSW |
1 |
130,188,572 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R5304:Thsd7b
|
UTSW |
1 |
129,678,243 (GRCm38) |
nonsense |
probably null |
|
|
R5422:Thsd7b
|
UTSW |
1 |
129,921,334 (GRCm38) |
missense |
probably benign |
0.41 |
|
R5495:Thsd7b
|
UTSW |
1 |
129,595,833 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5598:Thsd7b
|
UTSW |
1 |
129,595,841 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5620:Thsd7b
|
UTSW |
1 |
130,162,936 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5638:Thsd7b
|
UTSW |
1 |
129,595,533 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5640:Thsd7b
|
UTSW |
1 |
130,116,671 (GRCm38) |
nonsense |
probably null |
|
|
R5655:Thsd7b
|
UTSW |
1 |
129,628,934 (GRCm38) |
splice site |
probably null |
|
|
R5711:Thsd7b
|
UTSW |
1 |
129,760,402 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5823:Thsd7b
|
UTSW |
1 |
129,678,084 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5888:Thsd7b
|
UTSW |
1 |
130,210,320 (GRCm38) |
nonsense |
probably null |
|
|
R5932:Thsd7b
|
UTSW |
1 |
129,430,838 (GRCm38) |
missense |
probably benign |
|
|
R6243:Thsd7b
|
UTSW |
1 |
130,162,862 (GRCm38) |
missense |
probably benign |
0.21 |
|
R6258:Thsd7b
|
UTSW |
1 |
129,667,918 (GRCm38) |
missense |
probably benign |
|
|
R6260:Thsd7b
|
UTSW |
1 |
129,667,918 (GRCm38) |
missense |
probably benign |
|
|
R6399:Thsd7b
|
UTSW |
1 |
129,816,648 (GRCm38) |
missense |
probably benign |
0.13 |
|
R6437:Thsd7b
|
UTSW |
1 |
129,816,682 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6719:Thsd7b
|
UTSW |
1 |
130,159,714 (GRCm38) |
splice site |
probably null |
|
|
R6785:Thsd7b
|
UTSW |
1 |
129,430,907 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7304:Thsd7b
|
UTSW |
1 |
130,103,153 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7334:Thsd7b
|
UTSW |
1 |
130,195,275 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7414:Thsd7b
|
UTSW |
1 |
129,628,980 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7673:Thsd7b
|
UTSW |
1 |
129,915,750 (GRCm38) |
splice site |
probably null |
|
|
R7683:Thsd7b
|
UTSW |
1 |
129,595,946 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7861:Thsd7b
|
UTSW |
1 |
130,159,698 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8145:Thsd7b
|
UTSW |
1 |
129,760,299 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8241:Thsd7b
|
UTSW |
1 |
130,189,951 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8296:Thsd7b
|
UTSW |
1 |
129,595,456 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8355:Thsd7b
|
UTSW |
1 |
129,595,879 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8507:Thsd7b
|
UTSW |
1 |
129,678,053 (GRCm38) |
missense |
probably benign |
0.21 |
|
R8520:Thsd7b
|
UTSW |
1 |
129,921,420 (GRCm38) |
missense |
probably benign |
0.07 |
|
R8555:Thsd7b
|
UTSW |
1 |
129,595,454 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8682:Thsd7b
|
UTSW |
1 |
129,760,274 (GRCm38) |
nonsense |
probably null |
|
|
R8981:Thsd7b
|
UTSW |
1 |
129,595,450 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R9029:Thsd7b
|
UTSW |
1 |
130,159,689 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9133:Thsd7b
|
UTSW |
1 |
129,915,645 (GRCm38) |
missense |
probably benign |
0.18 |
|
R9194:Thsd7b
|
UTSW |
1 |
129,915,634 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R9229:Thsd7b
|
UTSW |
1 |
129,921,290 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9239:Thsd7b
|
UTSW |
1 |
130,159,716 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9460:Thsd7b
|
UTSW |
1 |
130,162,937 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9466:Thsd7b
|
UTSW |
1 |
130,195,129 (GRCm38) |
missense |
probably benign |
|
|
R9588:Thsd7b
|
UTSW |
1 |
130,180,486 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0027:Thsd7b
|
UTSW |
1 |
129,596,072 (GRCm38) |
missense |
probably benign |
0.00 |
|
Z1176:Thsd7b
|
UTSW |
1 |
129,628,911 (GRCm38) |
missense |
probably benign |
0.17 |
|
Z1176:Thsd7b
|
UTSW |
1 |
129,595,660 (GRCm38) |
missense |
probably benign |
0.01 |
|
Z1176:Thsd7b
|
UTSW |
1 |
129,595,516 (GRCm38) |
missense |
probably damaging |
0.98 |
|
Z1176:Thsd7b
|
UTSW |
1 |
130,180,424 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCCATTGAGTAATCGGCTAGC -3'
(R):5'- CTTAGTGGTCTGGAGATCCCTC -3'
Sequencing Primer
(F):5'- AGCTTAGGCATCCATTTCAGG -3'
(R):5'- CAGGGCCTATGTGATTTC -3'
|
| Posted On |
2015-11-11 |
Incidental Mutation