Incidental Mutation 'R4756:Nlrp9a'
| ID |
358012 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nlrp9a
|
| Ensembl Gene |
ENSMUSG00000054102 |
| Gene Name |
NLR family, pyrin domain containing 9A |
| Synonyms |
Nalp9a, Nalp-theta, D7Ertd565e |
| MMRRC Submission |
041972-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.060)
|
| Stock # |
R4756 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
26234448-26273573 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 26256866 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Asparagine
at position 161
(K161N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000113318
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071780]
[ENSMUST00000108387]
[ENSMUST00000117252]
[ENSMUST00000122040]
[ENSMUST00000153452]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000071780
AA Change: K161N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000071685
Gene: ENSMUSG00000054102
AA Change: K161N
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
1e-32 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.17e0 |
SMART |
|
LRR
|
807 |
834 |
2.27e-4 |
SMART |
|
LRR
|
836 |
863 |
2.02e2 |
SMART |
|
LRR
|
864 |
891 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108387
AA Change: K161N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000104024
Gene: ENSMUSG00000054102
AA Change: K161N
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
7.7e-33 |
PFAM |
|
LRR
|
631 |
658 |
1.42e0 |
SMART |
|
LRR
|
692 |
719 |
1.42e0 |
SMART |
|
LRR
|
748 |
775 |
2.32e-1 |
SMART |
|
LRR
|
777 |
804 |
3e0 |
SMART |
|
LRR
|
805 |
832 |
1.12e-3 |
SMART |
|
LRR
|
834 |
861 |
2.17e0 |
SMART |
|
LRR
|
862 |
889 |
2.27e-4 |
SMART |
|
LRR
|
891 |
918 |
2.02e2 |
SMART |
|
LRR
|
919 |
946 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000117252
AA Change: K161N
PolyPhen 2
Score 0.975 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000112398
Gene: ENSMUSG00000054102
AA Change: K161N
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
8.8e-34 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
Blast:LRR
|
666 |
692 |
1e-5 |
BLAST |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.39e0 |
SMART |
|
LRR
|
807 |
834 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000122040
AA Change: K161N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000113318
Gene: ENSMUSG00000054102
AA Change: K161N
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
1e-32 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.17e0 |
SMART |
|
LRR
|
807 |
834 |
2.27e-4 |
SMART |
|
LRR
|
836 |
863 |
2.02e2 |
SMART |
|
LRR
|
864 |
891 |
6.24e1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000143149
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000153452
AA Change: K72N
PolyPhen 2
Score 0.981 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000120498
Gene: ENSMUSG00000054102
AA Change: K72N
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NACHT
|
54 |
222 |
6.9e-33 |
PFAM |
|
LRR
|
542 |
569 |
1.42e0 |
SMART |
|
LRR
|
603 |
630 |
1.42e0 |
SMART |
|
Blast:LRR
|
632 |
657 |
1e-5 |
BLAST |
|
LRR
|
659 |
686 |
2.32e-1 |
SMART |
|
LRR
|
688 |
715 |
3e0 |
SMART |
|
LRR
|
716 |
743 |
1.12e-3 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 94.9%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930550C14Rik |
A |
T |
9: 53,336,830 (GRCm39) |
M45L |
probably benign |
Het |
| Acss2 |
T |
C |
2: 155,403,063 (GRCm39) |
F627L |
probably damaging |
Het |
| Akap8 |
A |
G |
17: 32,535,184 (GRCm39) |
S277P |
probably damaging |
Het |
| Akap9 |
T |
A |
5: 4,051,418 (GRCm39) |
M1395K |
probably damaging |
Het |
| Ank1 |
A |
G |
8: 23,612,893 (GRCm39) |
D1468G |
probably benign |
Het |
| Apoe |
A |
G |
7: 19,430,846 (GRCm39) |
V121A |
probably benign |
Het |
| Aqp9 |
A |
T |
9: 71,070,331 (GRCm39) |
L12H |
probably damaging |
Het |
| Atp2b4 |
G |
A |
1: 133,639,529 (GRCm39) |
A1115V |
probably benign |
Het |
| Atp2b4 |
G |
A |
1: 133,667,134 (GRCm39) |
P139L |
probably benign |
Het |
| B430218F22Rik |
T |
C |
13: 118,523,980 (GRCm39) |
|
probably benign |
Het |
| Bltp2 |
T |
A |
11: 78,154,854 (GRCm39) |
L122H |
probably damaging |
Het |
| Brsk1 |
A |
G |
7: 4,711,866 (GRCm39) |
E572G |
possibly damaging |
Het |
| C6 |
T |
C |
15: 4,811,394 (GRCm39) |
I414T |
probably benign |
Het |
| C8b |
T |
A |
4: 104,644,083 (GRCm39) |
M250K |
probably benign |
Het |
| Camk1g |
T |
A |
1: 193,044,393 (GRCm39) |
E7V |
probably benign |
Het |
| Clcc1 |
A |
G |
3: 108,580,236 (GRCm39) |
|
probably null |
Het |
| Col4a3 |
G |
T |
1: 82,694,018 (GRCm39) |
|
probably null |
Het |
| Cox5b |
T |
A |
1: 36,732,310 (GRCm39) |
W104R |
probably damaging |
Het |
| Cyp2c55 |
A |
C |
19: 39,019,815 (GRCm39) |
H251P |
probably damaging |
Het |
| Cyp2c67 |
G |
A |
19: 39,632,188 (GRCm39) |
T60I |
probably benign |
Het |
| Defb42 |
T |
A |
14: 63,285,824 (GRCm39) |
V68E |
probably benign |
Het |
| Ercc4 |
T |
A |
16: 12,941,287 (GRCm39) |
I225N |
probably damaging |
Het |
| Fam120b |
G |
T |
17: 15,622,658 (GRCm39) |
C212F |
probably damaging |
Het |
| Fgf10 |
T |
C |
13: 118,918,045 (GRCm39) |
V111A |
probably benign |
Het |
| Fn1 |
G |
T |
1: 71,629,967 (GRCm39) |
T2186K |
probably damaging |
Het |
| Fras1 |
T |
C |
5: 96,929,518 (GRCm39) |
V3974A |
probably benign |
Het |
| Galnt4 |
T |
C |
10: 98,944,362 (GRCm39) |
V29A |
probably benign |
Het |
| Gpr26 |
T |
C |
7: 131,569,230 (GRCm39) |
Y192H |
probably damaging |
Het |
| Heatr9 |
A |
T |
11: 83,407,475 (GRCm39) |
L236Q |
probably damaging |
Het |
| Hivep3 |
C |
A |
4: 119,955,020 (GRCm39) |
P1112H |
probably damaging |
Het |
| Hnf4g |
A |
G |
3: 3,708,069 (GRCm39) |
Y106C |
possibly damaging |
Het |
| Hnrnpdl |
A |
T |
5: 100,185,783 (GRCm39) |
Y69* |
probably null |
Het |
| Itgb1 |
G |
A |
8: 129,443,703 (GRCm39) |
A320T |
probably damaging |
Het |
| Kcna2 |
T |
C |
3: 107,012,733 (GRCm39) |
I438T |
probably benign |
Het |
| Kif24 |
A |
G |
4: 41,397,545 (GRCm39) |
|
probably null |
Het |
| Klhl1 |
G |
A |
14: 96,389,402 (GRCm39) |
T584I |
probably benign |
Het |
| Ltbp1 |
A |
G |
17: 75,532,199 (GRCm39) |
D91G |
probably damaging |
Het |
| Mdga2 |
T |
C |
12: 66,844,427 (GRCm39) |
I190M |
probably damaging |
Het |
| Meis2 |
G |
A |
2: 115,830,686 (GRCm39) |
R276C |
probably damaging |
Het |
| Mob4 |
C |
T |
1: 55,191,855 (GRCm39) |
R190W |
probably damaging |
Het |
| Mrgpra2a |
A |
G |
7: 47,077,114 (GRCm39) |
I48T |
possibly damaging |
Het |
| Mst1 |
T |
C |
9: 107,960,826 (GRCm39) |
V481A |
probably benign |
Het |
| Mttp |
A |
T |
3: 137,821,832 (GRCm39) |
V245E |
possibly damaging |
Het |
| Nbn |
T |
A |
4: 15,981,470 (GRCm39) |
S521T |
probably benign |
Het |
| Neb |
G |
T |
2: 52,083,243 (GRCm39) |
T5654N |
probably damaging |
Het |
| Nod2 |
T |
G |
8: 89,390,902 (GRCm39) |
F388C |
possibly damaging |
Het |
| Or3a1 |
G |
T |
11: 74,225,402 (GRCm39) |
F218L |
probably benign |
Het |
| Or4a75 |
G |
T |
2: 89,447,814 (GRCm39) |
H241N |
possibly damaging |
Het |
| Or4f58 |
A |
G |
2: 111,851,332 (GRCm39) |
F289S |
possibly damaging |
Het |
| Or52e2 |
A |
T |
7: 102,804,332 (GRCm39) |
N207K |
probably benign |
Het |
| Or7a38 |
T |
A |
10: 78,753,361 (GRCm39) |
I229N |
probably damaging |
Het |
| Or7g25 |
G |
A |
9: 19,160,153 (GRCm39) |
L181F |
possibly damaging |
Het |
| P2ry1 |
A |
G |
3: 60,911,898 (GRCm39) |
S346G |
probably benign |
Het |
| Polr1f |
T |
A |
12: 33,487,679 (GRCm39) |
|
probably null |
Het |
| Prkcd |
A |
G |
14: 30,321,623 (GRCm39) |
F524L |
probably benign |
Het |
| Qrfprl |
T |
C |
6: 65,429,898 (GRCm39) |
I198T |
probably benign |
Het |
| Ramp3 |
A |
T |
11: 6,624,843 (GRCm39) |
M46L |
probably benign |
Het |
| Rint1 |
T |
C |
5: 24,014,791 (GRCm39) |
Y278H |
probably damaging |
Het |
| Skint11 |
C |
T |
4: 114,051,874 (GRCm39) |
T74I |
probably benign |
Het |
| Slc10a7 |
T |
C |
8: 79,433,579 (GRCm39) |
|
probably null |
Het |
| Slc45a2 |
T |
A |
15: 11,028,016 (GRCm39) |
Y528* |
probably null |
Het |
| Slit1 |
A |
G |
19: 41,637,452 (GRCm39) |
F329L |
probably damaging |
Het |
| Sltm |
A |
T |
9: 70,498,892 (GRCm39) |
M989L |
possibly damaging |
Het |
| Smad9 |
A |
T |
3: 54,701,874 (GRCm39) |
T372S |
possibly damaging |
Het |
| Snrpc |
T |
A |
17: 28,061,306 (GRCm39) |
Y38* |
probably null |
Het |
| Spag17 |
A |
G |
3: 100,010,701 (GRCm39) |
K2065R |
possibly damaging |
Het |
| Stxbp4 |
T |
A |
11: 90,498,197 (GRCm39) |
K87N |
probably damaging |
Het |
| Tbc1d23 |
AT |
ATT |
16: 57,019,258 (GRCm39) |
|
probably null |
Het |
| Tgfb1i1 |
A |
T |
7: 127,848,571 (GRCm39) |
M96L |
probably damaging |
Het |
| Tnc |
T |
A |
4: 63,885,580 (GRCm39) |
I1841F |
probably damaging |
Het |
| Ubap2 |
G |
T |
4: 41,211,771 (GRCm39) |
H63Q |
probably damaging |
Het |
| Vps13a |
T |
C |
19: 16,632,580 (GRCm39) |
N2592S |
probably benign |
Het |
| Xdh |
G |
A |
17: 74,193,381 (GRCm39) |
P1305L |
probably benign |
Het |
| Xrn1 |
G |
A |
9: 95,921,862 (GRCm39) |
R1425K |
probably benign |
Het |
| Zfp418 |
G |
A |
7: 7,185,762 (GRCm39) |
R575Q |
possibly damaging |
Het |
| Zfp608 |
T |
A |
18: 55,027,544 (GRCm39) |
Q1424H |
probably damaging |
Het |
| Zfp839 |
C |
A |
12: 110,821,635 (GRCm39) |
L150I |
possibly damaging |
Het |
|
| Other mutations in Nlrp9a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00659:Nlrp9a
|
APN |
7 |
26,257,050 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL00895:Nlrp9a
|
APN |
7 |
26,258,103 (GRCm39) |
missense |
probably benign |
|
|
IGL01081:Nlrp9a
|
APN |
7 |
26,257,519 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01148:Nlrp9a
|
APN |
7 |
26,257,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01368:Nlrp9a
|
APN |
7 |
26,257,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01914:Nlrp9a
|
APN |
7 |
26,256,689 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01952:Nlrp9a
|
APN |
7 |
26,257,444 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02245:Nlrp9a
|
APN |
7 |
26,257,318 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02449:Nlrp9a
|
APN |
7 |
26,264,396 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02702:Nlrp9a
|
APN |
7 |
26,264,381 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02944:Nlrp9a
|
APN |
7 |
26,258,076 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL03183:Nlrp9a
|
APN |
7 |
26,256,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0005:Nlrp9a
|
UTSW |
7 |
26,273,213 (GRCm39) |
splice site |
probably benign |
|
|
R0007:Nlrp9a
|
UTSW |
7 |
26,250,515 (GRCm39) |
intron |
probably benign |
|
|
R0007:Nlrp9a
|
UTSW |
7 |
26,250,515 (GRCm39) |
intron |
probably benign |
|
|
R0013:Nlrp9a
|
UTSW |
7 |
26,270,650 (GRCm39) |
splice site |
probably null |
|
|
R0086:Nlrp9a
|
UTSW |
7 |
26,257,972 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0659:Nlrp9a
|
UTSW |
7 |
26,256,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1126:Nlrp9a
|
UTSW |
7 |
26,260,166 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1500:Nlrp9a
|
UTSW |
7 |
26,267,316 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1585:Nlrp9a
|
UTSW |
7 |
26,258,093 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1594:Nlrp9a
|
UTSW |
7 |
26,269,932 (GRCm39) |
nonsense |
probably null |
|
|
R1968:Nlrp9a
|
UTSW |
7 |
26,264,366 (GRCm39) |
missense |
probably benign |
0.23 |
|
R1989:Nlrp9a
|
UTSW |
7 |
26,273,338 (GRCm39) |
missense |
probably benign |
0.24 |
|
R2057:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2058:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2059:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2188:Nlrp9a
|
UTSW |
7 |
26,264,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2318:Nlrp9a
|
UTSW |
7 |
26,273,277 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3110:Nlrp9a
|
UTSW |
7 |
26,257,297 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3112:Nlrp9a
|
UTSW |
7 |
26,257,297 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3237:Nlrp9a
|
UTSW |
7 |
26,270,810 (GRCm39) |
nonsense |
probably null |
|
|
R3545:Nlrp9a
|
UTSW |
7 |
26,256,757 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3805:Nlrp9a
|
UTSW |
7 |
26,264,277 (GRCm39) |
nonsense |
probably null |
|
|
R4005:Nlrp9a
|
UTSW |
7 |
26,257,975 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4057:Nlrp9a
|
UTSW |
7 |
26,270,071 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4529:Nlrp9a
|
UTSW |
7 |
26,270,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4908:Nlrp9a
|
UTSW |
7 |
26,250,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4972:Nlrp9a
|
UTSW |
7 |
26,269,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4992:Nlrp9a
|
UTSW |
7 |
26,256,811 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5042:Nlrp9a
|
UTSW |
7 |
26,270,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5224:Nlrp9a
|
UTSW |
7 |
26,256,717 (GRCm39) |
missense |
probably benign |
0.43 |
|
R5449:Nlrp9a
|
UTSW |
7 |
26,257,254 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5644:Nlrp9a
|
UTSW |
7 |
26,257,993 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5734:Nlrp9a
|
UTSW |
7 |
26,270,065 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5905:Nlrp9a
|
UTSW |
7 |
26,257,762 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5978:Nlrp9a
|
UTSW |
7 |
26,256,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6028:Nlrp9a
|
UTSW |
7 |
26,257,762 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6066:Nlrp9a
|
UTSW |
7 |
26,257,510 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6082:Nlrp9a
|
UTSW |
7 |
26,267,402 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6171:Nlrp9a
|
UTSW |
7 |
26,258,188 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6352:Nlrp9a
|
UTSW |
7 |
26,257,051 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6490:Nlrp9a
|
UTSW |
7 |
26,250,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6540:Nlrp9a
|
UTSW |
7 |
26,256,817 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7039:Nlrp9a
|
UTSW |
7 |
26,267,367 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7151:Nlrp9a
|
UTSW |
7 |
26,256,672 (GRCm39) |
nonsense |
probably null |
|
|
R7173:Nlrp9a
|
UTSW |
7 |
26,257,603 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7214:Nlrp9a
|
UTSW |
7 |
26,250,463 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7226:Nlrp9a
|
UTSW |
7 |
26,258,149 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7250:Nlrp9a
|
UTSW |
7 |
26,258,143 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7293:Nlrp9a
|
UTSW |
7 |
26,270,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7492:Nlrp9a
|
UTSW |
7 |
26,257,081 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7586:Nlrp9a
|
UTSW |
7 |
26,256,721 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7844:Nlrp9a
|
UTSW |
7 |
26,262,006 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8073:Nlrp9a
|
UTSW |
7 |
26,260,260 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8136:Nlrp9a
|
UTSW |
7 |
26,256,678 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8400:Nlrp9a
|
UTSW |
7 |
26,264,431 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8415:Nlrp9a
|
UTSW |
7 |
26,256,925 (GRCm39) |
missense |
probably benign |
|
|
R8774:Nlrp9a
|
UTSW |
7 |
26,257,984 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8774-TAIL:Nlrp9a
|
UTSW |
7 |
26,257,984 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8882:Nlrp9a
|
UTSW |
7 |
26,257,703 (GRCm39) |
nonsense |
probably null |
|
|
R9023:Nlrp9a
|
UTSW |
7 |
26,273,291 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9031:Nlrp9a
|
UTSW |
7 |
26,257,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9063:Nlrp9a
|
UTSW |
7 |
26,273,291 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9090:Nlrp9a
|
UTSW |
7 |
26,261,944 (GRCm39) |
missense |
probably benign |
|
|
R9196:Nlrp9a
|
UTSW |
7 |
26,258,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9206:Nlrp9a
|
UTSW |
7 |
26,257,656 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9265:Nlrp9a
|
UTSW |
7 |
26,258,038 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R9271:Nlrp9a
|
UTSW |
7 |
26,261,944 (GRCm39) |
missense |
probably benign |
|
|
R9384:Nlrp9a
|
UTSW |
7 |
26,258,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9402:Nlrp9a
|
UTSW |
7 |
26,270,030 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9424:Nlrp9a
|
UTSW |
7 |
26,260,178 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9620:Nlrp9a
|
UTSW |
7 |
26,250,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9660:Nlrp9a
|
UTSW |
7 |
26,256,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9696:Nlrp9a
|
UTSW |
7 |
26,275,033 (GRCm39) |
missense |
unknown |
|
|
R9728:Nlrp9a
|
UTSW |
7 |
26,256,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9744:Nlrp9a
|
UTSW |
7 |
26,267,266 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9794:Nlrp9a
|
UTSW |
7 |
26,264,302 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1176:Nlrp9a
|
UTSW |
7 |
26,257,654 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Nlrp9a
|
UTSW |
7 |
26,256,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCAGCACATATGGACAATGGAG -3'
(R):5'- GTCCTGAGTTCCAAGTCAAATTTC -3'
Sequencing Primer
(F):5'- TGGAGACCAACACTTATATACCTG -3'
(R):5'- TTCAGGTAATCAAATCCATCCAGG -3'
|
| Posted On |
2015-11-11 |
Incidental Mutation