Mutagenetix > Incidental Mutation

Incidental Mutation 'R4732:Ccdc88a'

359090

Institutional Source

Beutler Lab

Gene Symbol

Ccdc88a

Ensembl Gene

ENSMUSG00000032740

Gene Name

coiled coil domain containing 88A

Synonyms

Girdin, GIV, A430106J12Rik, D130005J21Rik, HkRP1, C130096N06Rik, C330012F17Rik

MMRRC Submission

042022-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R4732 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

29373658-29510808 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to G at 29485906 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Lysine at position 1276 (N1276K)

Ref Sequence

ENSEMBL: ENSMUSP00000048978 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000040182] [ENSMUST00000140194] [ENSMUST00000155854]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000040182
AA Change: N1276K

PolyPhen 2 Score 0.020 (Sensitivity: 0.95; Specificity: 0.80)

SMART Domains

Protein: ENSMUSP00000048978
Gene: ENSMUSG00000032740
AA Change: N1276K

Domain	Start	End	E-Value	Type
Pfam:HOOK	14	590	8.1e-36	PFAM
low complexity region	614	625	N/A	INTRINSIC
Blast:BRLZ	665	719	6e-22	BLAST
low complexity region	826	839	N/A	INTRINSIC
low complexity region	883	895	N/A	INTRINSIC
low complexity region	955	985	N/A	INTRINSIC
low complexity region	1093	1104	N/A	INTRINSIC
coiled coil region	1268	1385	N/A	INTRINSIC
low complexity region	1437	1444	N/A	INTRINSIC
low complexity region	1566	1576	N/A	INTRINSIC
internal_repeat_1	1609	1702	2.38e-6	PROSPERO
internal_repeat_1	1708	1808	2.38e-6	PROSPERO
low complexity region	1811	1824	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000123561
AA Change: N256K

SMART Domains

Protein: ENSMUSP00000119173
Gene: ENSMUSG00000032740
AA Change: N256K

Domain	Start	End	E-Value	Type
coiled coil region	1	212	N/A	INTRINSIC
coiled coil region	248	365	N/A	INTRINSIC
low complexity region	418	425	N/A	INTRINSIC
low complexity region	547	557	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000140194

SMART Domains

Protein: ENSMUSP00000114942
Gene: ENSMUSG00000032740

Domain	Start	End	E-Value	Type
coiled coil region	3	85	N/A	INTRINSIC
low complexity region	137	144	N/A	INTRINSIC
low complexity region	294	304	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000155854

SMART Domains

Protein: ENSMUSP00000115117
Gene: ENSMUSG00000032740

Domain	Start	End	E-Value	Type
low complexity region	18	31	N/A	INTRINSIC
low complexity region	75	87	N/A	INTRINSIC
low complexity region	146	176	N/A	INTRINSIC
Blast:BRLZ	228	283	7e-6	BLAST
low complexity region	284	295	N/A	INTRINSIC

Meta Mutation Damage Score

0.0925

Coding Region Coverage

1x: 99.3%
3x: 98.7%
10x: 97.2%
20x: 95.1%

Validation Efficiency

99% (110/111)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal weight loss, reduced angiogenesis, and premature death by P25. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 192 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700128F08Rik	T	A	9: 8,222,173		noncoding transcript	Het
3110035E14Rik	T	C	1: 9,606,976	S24P	probably benign	Het
4933409G03Rik	A	G	2: 68,614,721		probably benign	Het
Acan	T	C	7: 79,098,609	S1043P	probably damaging	Het
Ackr2	A	G	9: 121,909,183	Y208C	probably damaging	Het
Actg1	C	T	11: 120,347,479		probably benign	Het
Adam1a	T	A	5: 121,519,434	T599S	probably benign	Het
Adamts12	A	T	15: 11,270,662	S668C	probably damaging	Het
Adcy8	A	G	15: 64,754,862	V709A	possibly damaging	Het
Adgrf2	A	C	17: 42,710,754	I393S	probably damaging	Het
Ahnak	G	T	19: 9,007,301	G1983V	probably damaging	Het
AI413582	A	G	17: 27,565,270		probably benign	Het
Aim2	T	A	1: 173,463,876	D282E	possibly damaging	Het
Ak8	A	G	2: 28,760,071	Y370C	probably damaging	Het
Akap9	A	G	5: 4,013,901	D1750G	probably damaging	Het
Als2cl	T	A	9: 110,889,136	V315E	probably damaging	Het
Ankrd28	A	C	14: 31,755,741	C115G	probably benign	Het
Ap3b2	C	T	7: 81,471,932	A519T	probably damaging	Het
Apool	C	T	X: 112,372,200	T166I	probably damaging	Het
Arhgef2	A	T	3: 88,631,940	K65*	probably null	Het
Arhgef38	G	T	3: 133,132,269	Y633*	probably null	Het
Asah2	T	C	19: 31,995,358	N659S	probably benign	Het
Atf7ip2	A	G	16: 10,241,886	D430G	possibly damaging	Het
Atp8a1	G	A	5: 67,813,120	S92L	probably benign	Het
Bag4	C	T	8: 25,769,488	A228T	probably benign	Het
BC024978	T	A	7: 27,201,043	M149K	probably damaging	Het
C130073F10Rik	C	A	4: 101,890,710	S89I	probably benign	Het
Cacna1g	T	C	11: 94,443,215	T867A	probably damaging	Het
Cdc42bpg	T	A	19: 6,311,191	V282E	probably damaging	Het
Cdipt	T	A	7: 126,978,358	L92H	probably damaging	Het
Celsr2	T	A	3: 108,398,952	D2012V	probably damaging	Het
Cenpt	A	G	8: 105,847,136	V254A	probably benign	Het
Cep104	T	A	4: 153,988,426	D380E	probably damaging	Het
Cers5	C	T	15: 99,741,637	R123Q	probably benign	Het
Ces2h	A	G	8: 105,014,604	E76G	probably damaging	Het
Cfap77	T	A	2: 28,984,388	E143D	probably benign	Het
Chmp7	C	A	14: 69,732,296	R65L	probably damaging	Het
Cldnd2	T	A	7: 43,442,189	C65S	possibly damaging	Het
Clec2g	C	A	6: 128,981,879	Y142*	probably null	Het
Coch	A	T	12: 51,605,019	E549V	probably benign	Het
Cog7	T	C	7: 121,964,244	D215G	probably benign	Het
Col4a2	A	G	8: 11,446,197	H1606R	probably benign	Het
Col4a2	T	C	8: 11,414,779	V348A	probably benign	Het
Cpd	T	C	11: 76,811,794	N583D	probably damaging	Het
Cyp2d11	T	A	15: 82,389,227	Y481F	probably benign	Het
D130043K22Rik	T	C	13: 24,899,665	S1038P	probably damaging	Het
Deptor	C	A	15: 55,181,010	H191N	probably benign	Het
Dgkz	A	T	2: 91,938,339	I699N	probably damaging	Het
Dnah12	C	T	14: 26,781,784	T1653I	probably damaging	Het
Dnah7c	T	A	1: 46,770,173	N3550K	probably damaging	Het
Dnah8	A	G	17: 30,775,061	K3384R	probably null	Het
Dnajc11	A	G	4: 151,970,967		probably benign	Het
Dnajc13	CT	C	9: 104,186,805		probably benign	Het
Dnhd1	C	A	7: 105,673,849	N521K	probably benign	Het
Drg2	T	C	11: 60,461,396		probably null	Het
Dync1h1	C	T	12: 110,649,507	Q3030*	probably null	Het
Efhb	G	A	17: 53,426,244	T533I	probably damaging	Het
Eif2d	T	C	1: 131,164,727	V374A	probably damaging	Het
Etfb	T	C	7: 43,444,200	V17A	probably damaging	Het
F5	C	T	1: 164,181,657	T332M	probably damaging	Het
Fcho1	T	C	8: 71,716,795	T156A	probably benign	Het
Fn1	A	T	1: 71,602,512		probably null	Het
Fnip2	A	T	3: 79,481,652	S561T	probably damaging	Het
Frs2	T	A	10: 117,074,093	T455S	probably benign	Het
Fry	G	A	5: 150,386,007	E639K		Het
Fto	T	A	8: 91,409,714	D205E	probably damaging	Het
Galntl6	G	A	8: 58,427,813	P147L	probably damaging	Het
Gigyf1	T	A	5: 137,524,770	D844E	probably benign	Het
Gle1	T	C	2: 29,940,232	S267P	probably damaging	Het
Glg1	G	A	8: 111,187,755	R466W	probably damaging	Het
Gm10277	T	C	11: 77,786,097		probably benign	Het
Gm20388	A	G	8: 122,270,274		probably benign	Het
Gm5724	A	T	6: 141,723,179	M509K	probably benign	Het
Gm6871	T	C	7: 41,546,749	I39V	probably benign	Het
Gm9970	A	G	5: 31,241,066		probably benign	Het
Gpr35	T	G	1: 92,983,385	I57S	probably damaging	Het
Gprin1	C	T	13: 54,739,957	G168E	possibly damaging	Het
Gtdc1	A	G	2: 44,789,055		probably benign	Het
Gtf3c2	G	T	5: 31,160,057	P586T	probably damaging	Het
Gucy1a2	A	T	9: 3,759,424	H410L	probably benign	Het
Gucy2c	A	G	6: 136,767,152	S150P	probably damaging	Het
Ifi214	T	C	1: 173,526,591	Q171R	probably benign	Het
Ifit1bl1	T	C	19: 34,594,321	I245M	probably benign	Het
Igkv4-50	T	C	6: 69,701,000	K40R	probably benign	Het
Igkv8-18	T	A	6: 70,356,296	I74N	probably damaging	Het
Il2ra	T	A	2: 11,676,920	M112K	probably benign	Het
Itpr2	A	G	6: 146,373,173	F837S	probably damaging	Het
Kbtbd7	T	C	14: 79,428,800	*691Q	probably null	Het
Kcnn2	T	A	18: 45,560,349	S331T	possibly damaging	Het
Khnyn	T	A	14: 55,886,489		probably null	Het
Kif26a	G	A	12: 112,175,573	A754T	probably benign	Het
Klra3	T	A	6: 130,327,132	Y199F	possibly damaging	Het
Lhx2	A	G	2: 38,359,991	K274R	probably damaging	Het
Lrp2	T	C	2: 69,533,555	I313V	probably benign	Het
Lrrfip1	A	T	1: 91,115,647	E591D	probably benign	Het
Lrrk2	A	C	15: 91,688,849	E200A	probably damaging	Het
Lrrk2	G	A	15: 91,765,747	E1696K	probably damaging	Het
Mast4	A	T	13: 102,772,572	M465K	probably damaging	Het
Moxd2	T	G	6: 40,878,859	I599L	probably benign	Het
Mug2	T	C	6: 122,071,872	S866P	probably damaging	Het
Ncam2	A	G	16: 81,434,884	T79A	possibly damaging	Het
Ncoa6	C	A	2: 155,421,301	Q404H	probably damaging	Het
Neb	A	G	2: 52,279,079	Y1815H	probably damaging	Het
Nell1	A	G	7: 50,856,217	D724G	probably damaging	Het
Nkx3-2	A	G	5: 41,762,144	V167A	probably benign	Het
Nsun3	C	A	16: 62,735,119	C348F	possibly damaging	Het
Obox6	A	T	7: 15,834,772	S60T	possibly damaging	Het
Olfr1	T	C	11: 73,395,695	D109G	probably benign	Het
Olfr1378	G	A	11: 50,969,266	V83M	possibly damaging	Het
Olfr138	T	A	17: 38,275,547	Y259N	probably damaging	Het
Olfr466	T	C	13: 65,152,653	V143A	possibly damaging	Het
Olfr744	T	A	14: 50,618,569	C116S	probably benign	Het
Olfr94	T	C	17: 37,197,024	T315A	probably damaging	Het
Olfr980	A	T	9: 40,006,268	I227N	probably damaging	Het
Oog2	T	A	4: 144,193,941		probably benign	Het
Pabpc1	A	T	15: 36,599,284	V389E	probably benign	Het
Pank4	A	T	4: 154,971,390	M291L	probably benign	Het
Pcf11	T	C	7: 92,658,833	D709G	probably benign	Het
Pcgf1	T	A	6: 83,079,957		probably benign	Het
Pcnx	A	G	12: 81,995,751	I2256V	probably benign	Het
Pex6	A	G	17: 46,722,288	D579G	probably benign	Het
Pex6	A	G	17: 46,724,707		probably null	Het
Piezo2	C	T	18: 63,030,401	A2149T	probably damaging	Het
Pik3c2g	A	G	6: 139,935,985	E781G	probably benign	Het
Pik3r4	G	A	9: 105,678,176	V1111I	possibly damaging	Het
Pkd1l2	T	A	8: 116,995,842		probably null	Het
Plekhg1	T	A	10: 3,957,506	S808T	probably benign	Het
Pnkp	T	A	7: 44,860,454		probably benign	Het
Polr3c	A	T	3: 96,723,661	F148I	probably damaging	Het
Ppard	A	T	17: 28,286,443	T35S	probably benign	Het
Ptov1	T	C	7: 44,867,109	D134G	probably benign	Het
Ptprz1	T	A	6: 23,002,610	S1566R	probably benign	Het
Pum1	T	C	4: 130,718,193	S158P	probably benign	Het
Qk	T	C	17: 10,216,288	H269R	probably damaging	Het
Qrsl1	T	C	10: 43,876,663	Y388C	probably damaging	Het
Rapgef1	T	G	2: 29,689,160	I182S	probably damaging	Het
Ret	T	C	6: 118,163,193	S1013G	possibly damaging	Het
Rimbp3	A	G	16: 17,210,601	R630G	possibly damaging	Het
Rnmt	A	T	18: 68,317,960		probably benign	Het
Ryr2	A	T	13: 11,577,909	M4653K	possibly damaging	Het
Sacm1l	G	A	9: 123,590,830	V553I	probably benign	Het
Sec31b	A	T	19: 44,532,677	S110T	probably damaging	Het
Serpina3k	G	A	12: 104,340,860	G117D	probably damaging	Het
Sesn2	T	C	4: 132,494,591	Y410C	probably damaging	Het
Slc24a1	G	A	9: 64,949,554	R24C	probably benign	Het
Slc35g2	A	C	9: 100,552,502	V372G	probably benign	Het
Slc7a7	T	C	14: 54,408,733	Y91C	probably damaging	Het
Slc7a9	T	A	7: 35,453,563	Y135*	probably null	Het
Slco4a1	A	G	2: 180,473,615	N662D	probably damaging	Het
Slfn4	T	A	11: 83,189,282		probably benign	Het
Slmap	T	C	14: 26,468,535	N156S	probably damaging	Het
Snx18	A	G	13: 113,617,774	S208P	probably benign	Het
Sorbs1	T	A	19: 40,314,689	R485S	probably benign	Het
Spib	A	G	7: 44,528,885	S154P	probably damaging	Het
Spty2d1	T	C	7: 46,996,110	D595G	probably damaging	Het
St7	T	A	6: 17,906,516		probably null	Het
Susd1	T	C	4: 59,428,029	T52A	possibly damaging	Het
Svs2	T	A	2: 164,237,123	D288V	possibly damaging	Het
Syt7	T	A	19: 10,442,924	I355N	probably damaging	Het
Tarm1	G	A	7: 3,496,900	Q145*	probably null	Het
Teddm2	T	A	1: 153,850,741	E76V	probably damaging	Het
Thsd7b	T	C	1: 129,613,186	S343P	probably damaging	Het
Tigd2	T	A	6: 59,211,415	H422Q	probably benign	Het
Tle1	T	C	4: 72,125,019	N538D	possibly damaging	Het
Tmc2	A	G	2: 130,261,397		probably null	Het
Tmtc1	A	C	6: 148,284,980		probably null	Het
Tns3	C	T	11: 8,450,986	R1104H	probably benign	Het
Trim6	T	C	7: 104,232,648	Y369H	probably damaging	Het
Triobp	G	A	15: 78,967,113	R489K	probably damaging	Het
Trpv4	T	C	5: 114,622,753	D732G	possibly damaging	Het
Trrap	G	A	5: 144,816,570	V1883I	probably damaging	Het
Tsc2	C	A	17: 24,603,275	V1141F	possibly damaging	Het
Ttn	A	T	2: 76,943,011	M2395K	unknown	Het
Ttn	A	G	2: 76,899,827		probably benign	Het
Tyrp1	A	T	4: 80,844,935	D353V	possibly damaging	Het
Ubd	A	C	17: 37,195,702	T160P	probably benign	Het
Ugt2b36	G	T	5: 87,081,538	Y156*	probably null	Het
Ulk4	G	A	9: 121,263,638	R178*	probably null	Het
Unc13d	A	G	11: 116,073,582	V312A	possibly damaging	Het
Urb2	G	T	8: 124,028,897	A448S	probably damaging	Het
Urod	G	A	4: 116,991,673	A92V	possibly damaging	Het
Vmn1r33	T	A	6: 66,611,819	R250S	probably benign	Het
Vmn1r87	A	T	7: 13,132,327	M11K	possibly damaging	Het
Vmn2r77	C	T	7: 86,800,987	T147I	probably benign	Het
Vstm4	A	G	14: 32,917,902	K96E	possibly damaging	Het
Washc4	A	T	10: 83,574,479	M644L	probably benign	Het
Wwp1	T	C	4: 19,661,990	D172G	probably benign	Het
Zbtb38	A	T	9: 96,687,684	V449E	probably damaging	Het
Zfhx4	T	C	3: 5,214,807		probably benign	Het
Zfp229	C	T	17: 21,745,286	H166Y	possibly damaging	Het
Zfp512b	A	G	2: 181,588,739	S453P	probably benign	Het
Zp2	C	A	7: 120,138,120	V282L	probably damaging	Het

Other mutations in Ccdc88a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00499:Ccdc88a	APN	11	29499341	missense	probably benign	0.24
IGL00577:Ccdc88a	APN	11	29424772	missense	probably damaging	1.00
IGL00766:Ccdc88a	APN	11	29501046	missense	probably damaging	0.99
IGL01384:Ccdc88a	APN	11	29503915	missense	probably damaging	0.99
IGL01541:Ccdc88a	APN	11	29400283	missense	probably benign
IGL01647:Ccdc88a	APN	11	29504321	unclassified	probably benign
IGL02648:Ccdc88a	APN	11	29501051	missense	probably benign	0.28
IGL02885:Ccdc88a	APN	11	29448050	missense	probably damaging	1.00
IGL03117:Ccdc88a	APN	11	29374559	missense	probably damaging	1.00
IGL03196:Ccdc88a	APN	11	29482340	missense	possibly damaging	0.56
trailor	UTSW	11	29494099	splice site	probably null
R0011:Ccdc88a	UTSW	11	29374364	missense	probably damaging	1.00
R0011:Ccdc88a	UTSW	11	29374364	missense	probably damaging	1.00
R0083:Ccdc88a	UTSW	11	29503463	missense	probably damaging	0.99
R0108:Ccdc88a	UTSW	11	29503463	missense	probably damaging	0.99
R0326:Ccdc88a	UTSW	11	29461021	missense	probably benign	0.01
R0565:Ccdc88a	UTSW	11	29461042	unclassified	probably benign
R0631:Ccdc88a	UTSW	11	29493752	missense	probably damaging	0.98
R0632:Ccdc88a	UTSW	11	29482749	unclassified	probably benign
R0762:Ccdc88a	UTSW	11	29463112	unclassified	probably benign
R0838:Ccdc88a	UTSW	11	29400285	missense	probably damaging	1.00
R0946:Ccdc88a	UTSW	11	29456509	missense	probably benign
R1192:Ccdc88a	UTSW	11	29504049	missense	possibly damaging	0.45
R1500:Ccdc88a	UTSW	11	29482713	missense	probably benign	0.00
R1701:Ccdc88a	UTSW	11	29477427	missense	possibly damaging	0.59
R1826:Ccdc88a	UTSW	11	29489637	missense	possibly damaging	0.58
R1902:Ccdc88a	UTSW	11	29461788	missense	probably benign	0.07
R1903:Ccdc88a	UTSW	11	29461788	missense	probably benign	0.07
R2021:Ccdc88a	UTSW	11	29503480	missense	probably damaging	1.00
R2023:Ccdc88a	UTSW	11	29463546	nonsense	probably null
R2284:Ccdc88a	UTSW	11	29494099	splice site	probably null
R3236:Ccdc88a	UTSW	11	29447995	missense	possibly damaging	0.51
R3409:Ccdc88a	UTSW	11	29486006	missense	probably damaging	1.00
R3410:Ccdc88a	UTSW	11	29486006	missense	probably damaging	1.00
R3411:Ccdc88a	UTSW	11	29486006	missense	probably damaging	1.00
R3430:Ccdc88a	UTSW	11	29448033	missense	probably damaging	0.98
R3620:Ccdc88a	UTSW	11	29430227	missense	probably benign	0.16
R4204:Ccdc88a	UTSW	11	29463399	missense	probably damaging	1.00
R4515:Ccdc88a	UTSW	11	29482651	missense	probably benign	0.01
R4518:Ccdc88a	UTSW	11	29482651	missense	probably benign	0.01
R4519:Ccdc88a	UTSW	11	29482651	missense	probably benign	0.01
R4693:Ccdc88a	UTSW	11	29482241	missense	probably damaging	1.00
R4705:Ccdc88a	UTSW	11	29422586	missense	probably benign
R4707:Ccdc88a	UTSW	11	29447956	missense	probably benign
R4733:Ccdc88a	UTSW	11	29485906	missense	probably benign	0.02
R4734:Ccdc88a	UTSW	11	29482720	missense	probably benign
R4749:Ccdc88a	UTSW	11	29482720	missense	probably benign
R4817:Ccdc88a	UTSW	11	29460907	missense	probably benign	0.15
R4828:Ccdc88a	UTSW	11	29463210	missense	probably damaging	1.00
R4979:Ccdc88a	UTSW	11	29482133	nonsense	probably null
R5288:Ccdc88a	UTSW	11	29498416	missense	possibly damaging	0.77
R5373:Ccdc88a	UTSW	11	29463409	missense	possibly damaging	0.92
R5374:Ccdc88a	UTSW	11	29463409	missense	possibly damaging	0.92
R5401:Ccdc88a	UTSW	11	29463279	missense	probably benign	0.00
R5586:Ccdc88a	UTSW	11	29503484	missense	probably benign	0.00
R6660:Ccdc88a	UTSW	11	29482663	missense	probably benign	0.01
R7116:Ccdc88a	UTSW	11	29504051	missense	probably benign	0.01
R7353:Ccdc88a	UTSW	11	29463368	missense	probably benign	0.00
R7538:Ccdc88a	UTSW	11	29463370	missense	probably benign	0.00
R7663:Ccdc88a	UTSW	11	29498614	critical splice donor site	probably null
R7769:Ccdc88a	UTSW	11	29482381	missense	probably damaging	1.00
R7798:Ccdc88a	UTSW	11	29477348	missense	probably benign	0.15
R7810:Ccdc88a	UTSW	11	29485964	missense	probably damaging	1.00
R7826:Ccdc88a	UTSW	11	29503563	missense	probably benign	0.02
R7956:Ccdc88a	UTSW	11	29463892	missense	probably damaging	1.00
R8260:Ccdc88a	UTSW	11	29493934	missense	probably benign	0.01
R8402:Ccdc88a	UTSW	11	29463879	missense	probably damaging	1.00
R8409:Ccdc88a	UTSW	11	29503544	missense	probably benign
R8555:Ccdc88a	UTSW	11	29430169	missense	probably benign
R8676:Ccdc88a	UTSW	11	29460860	missense	probably benign	0.05
R8846:Ccdc88a	UTSW	11	29464185	missense	probably damaging	1.00
R8963:Ccdc88a	UTSW	11	29498416	missense	possibly damaging	0.77
R8972:Ccdc88a	UTSW	11	29485888	missense	probably benign	0.07
R9353:Ccdc88a	UTSW	11	29477433	missense	probably damaging	1.00
R9362:Ccdc88a	UTSW	11	29503922	missense	probably null	0.55
R9385:Ccdc88a	UTSW	11	29455422	missense	probably benign	0.24
R9509:Ccdc88a	UTSW	11	29464143	missense	probably benign	0.27
R9610:Ccdc88a	UTSW	11	29477316	missense	possibly damaging	0.76
R9611:Ccdc88a	UTSW	11	29477316	missense	possibly damaging	0.76
R9664:Ccdc88a	UTSW	11	29455484	missense	probably benign	0.08
R9720:Ccdc88a	UTSW	11	29463813	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- CTGATTATTGATCAATTAGAGACTGGC -3'
(R):5'- ATACACCAGTAAGTCTATGTACTAAGG -3'

Sequencing Primer
(F):5'- TAGAGACTGGCAAATATGTCTGAATG -3'
(R):5'- ATGTACTAAGGCTGCCACTG -3'

Posted On

2015-11-11