Incidental Mutation 'R4739:Plxna1'
| ID |
359515 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxna1
|
| Ensembl Gene |
ENSMUSG00000030084 |
| Gene Name |
plexin A1 |
| Synonyms |
NOV, PlexA1, Plxn1, 2600013D04Rik |
| MMRRC Submission |
042025-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.895)
|
| Stock # |
R4739 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
89293295-89339595 bp(-) (GRCm39) |
| Type of Mutation |
splice site (6 bp from exon) |
| DNA Base Change (assembly) |
A to T
at 89309657 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131840
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000049845]
[ENSMUST00000049845]
[ENSMUST00000163139]
[ENSMUST00000163139]
|
| AlphaFold |
P70206 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000049845
|
| SMART Domains |
Protein: ENSMUSP00000063066
Gene: ENSMUSG00000030084
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
Sema
|
49 |
494 |
7.43e-126 |
SMART |
|
PSI
|
512 |
562 |
6.4e-11 |
SMART |
|
PSI
|
658 |
705 |
9.78e-7 |
SMART |
|
low complexity region
|
759 |
772 |
N/A |
INTRINSIC |
|
PSI
|
806 |
860 |
7.24e-10 |
SMART |
|
IPT
|
861 |
957 |
3.2e-26 |
SMART |
|
IPT
|
958 |
1043 |
1.59e-21 |
SMART |
|
IPT
|
1045 |
1145 |
6.86e-26 |
SMART |
|
IPT
|
1147 |
1242 |
1.64e-5 |
SMART |
|
transmembrane domain
|
1243 |
1265 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1316 |
1864 |
8.8e-263 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000049845
|
| SMART Domains |
Protein: ENSMUSP00000063066
Gene: ENSMUSG00000030084
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
Sema
|
49 |
494 |
7.43e-126 |
SMART |
|
PSI
|
512 |
562 |
6.4e-11 |
SMART |
|
PSI
|
658 |
705 |
9.78e-7 |
SMART |
|
low complexity region
|
759 |
772 |
N/A |
INTRINSIC |
|
PSI
|
806 |
860 |
7.24e-10 |
SMART |
|
IPT
|
861 |
957 |
3.2e-26 |
SMART |
|
IPT
|
958 |
1043 |
1.59e-21 |
SMART |
|
IPT
|
1045 |
1145 |
6.86e-26 |
SMART |
|
IPT
|
1147 |
1242 |
1.64e-5 |
SMART |
|
transmembrane domain
|
1243 |
1265 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1316 |
1864 |
8.8e-263 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000163139
|
| SMART Domains |
Protein: ENSMUSP00000131840
Gene: ENSMUSG00000030084
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
Sema
|
49 |
494 |
7.43e-126 |
SMART |
|
PSI
|
512 |
562 |
6.4e-11 |
SMART |
|
PSI
|
658 |
705 |
9.78e-7 |
SMART |
|
low complexity region
|
759 |
772 |
N/A |
INTRINSIC |
|
PSI
|
806 |
860 |
7.24e-10 |
SMART |
|
IPT
|
861 |
957 |
3.2e-26 |
SMART |
|
IPT
|
958 |
1043 |
1.59e-21 |
SMART |
|
IPT
|
1045 |
1145 |
6.86e-26 |
SMART |
|
IPT
|
1147 |
1242 |
1.64e-5 |
SMART |
|
transmembrane domain
|
1243 |
1265 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1315 |
1864 |
2.5e-264 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000163139
|
| SMART Domains |
Protein: ENSMUSP00000131840
Gene: ENSMUSG00000030084
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
27 |
N/A |
INTRINSIC |
|
Sema
|
49 |
494 |
7.43e-126 |
SMART |
|
PSI
|
512 |
562 |
6.4e-11 |
SMART |
|
PSI
|
658 |
705 |
9.78e-7 |
SMART |
|
low complexity region
|
759 |
772 |
N/A |
INTRINSIC |
|
PSI
|
806 |
860 |
7.24e-10 |
SMART |
|
IPT
|
861 |
957 |
3.2e-26 |
SMART |
|
IPT
|
958 |
1043 |
1.59e-21 |
SMART |
|
IPT
|
1045 |
1145 |
6.86e-26 |
SMART |
|
IPT
|
1147 |
1242 |
1.64e-5 |
SMART |
|
transmembrane domain
|
1243 |
1265 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1315 |
1864 |
2.5e-264 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000204997
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000205121
|
| Meta Mutation Damage Score |
0.9755 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.5%
|
| Validation Efficiency |
96% (102/106) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele exhibit bone cellularity abnormalities, altered dendritic cell physiology, abnormal proprioceptive and oligodendrocyte morphology, and increased lymphatic branching complexity and LEC numbers. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1600012P17Rik |
C |
T |
1: 158,796,904 (GRCm39) |
|
noncoding transcript |
Het |
| 2300002M23Rik |
A |
G |
17: 35,878,403 (GRCm39) |
|
probably benign |
Het |
| Aadat |
T |
C |
8: 60,993,140 (GRCm39) |
V360A |
probably benign |
Het |
| Abcc5 |
T |
A |
16: 20,218,376 (GRCm39) |
D283V |
probably damaging |
Het |
| Abraxas1 |
T |
A |
5: 100,959,886 (GRCm39) |
K155N |
probably damaging |
Het |
| Acot3 |
T |
C |
12: 84,105,364 (GRCm39) |
I277T |
probably benign |
Het |
| Ankrd45 |
G |
A |
1: 160,982,960 (GRCm39) |
C157Y |
probably damaging |
Het |
| Apol10a |
C |
T |
15: 77,372,841 (GRCm39) |
T159I |
possibly damaging |
Het |
| Arhgef11 |
G |
A |
3: 87,605,306 (GRCm39) |
V214M |
possibly damaging |
Het |
| Ash1l |
A |
C |
3: 88,890,152 (GRCm39) |
N677T |
probably benign |
Het |
| Atg13 |
A |
G |
2: 91,515,040 (GRCm39) |
S254P |
probably damaging |
Het |
| Atg16l2 |
A |
G |
7: 100,946,385 (GRCm39) |
L129P |
probably damaging |
Het |
| Avl9 |
T |
A |
6: 56,703,294 (GRCm39) |
V120D |
probably damaging |
Het |
| Castor1 |
A |
G |
11: 4,169,004 (GRCm39) |
E57G |
possibly damaging |
Het |
| Cc2d1b |
T |
C |
4: 108,485,239 (GRCm39) |
V527A |
probably benign |
Het |
| Ccnl1 |
A |
G |
3: 65,854,092 (GRCm39) |
|
probably benign |
Het |
| Cenpl |
T |
A |
1: 160,910,837 (GRCm39) |
D261E |
probably damaging |
Het |
| Cep192 |
T |
G |
18: 67,984,803 (GRCm39) |
I1604M |
probably benign |
Het |
| Cep95 |
A |
G |
11: 106,706,560 (GRCm39) |
I573V |
probably benign |
Het |
| Cfap100 |
A |
G |
6: 90,389,825 (GRCm39) |
|
probably null |
Het |
| Ciao3 |
A |
T |
17: 26,000,283 (GRCm39) |
H322L |
probably damaging |
Het |
| Cmc1 |
T |
A |
9: 117,904,245 (GRCm39) |
M49L |
probably benign |
Het |
| Cyfip2 |
G |
T |
11: 46,170,820 (GRCm39) |
N176K |
probably damaging |
Het |
| Cyp2w1 |
T |
C |
5: 139,342,430 (GRCm39) |
F408L |
probably damaging |
Het |
| D630045J12Rik |
G |
A |
6: 38,172,971 (GRCm39) |
S399F |
possibly damaging |
Het |
| Dcbld2 |
T |
A |
16: 58,281,339 (GRCm39) |
L528Q |
probably damaging |
Het |
| Dip2b |
T |
C |
15: 100,105,658 (GRCm39) |
V1138A |
probably damaging |
Het |
| Dip2c |
T |
A |
13: 9,583,375 (GRCm39) |
L119Q |
probably damaging |
Het |
| Dnah3 |
T |
C |
7: 119,677,169 (GRCm39) |
D444G |
possibly damaging |
Het |
| Dsg1c |
A |
T |
18: 20,408,246 (GRCm39) |
N432Y |
possibly damaging |
Het |
| Dst |
T |
A |
1: 34,230,228 (GRCm39) |
I2785N |
probably benign |
Het |
| Dynap |
A |
T |
18: 70,374,296 (GRCm39) |
Y77N |
possibly damaging |
Het |
| Eif4g3 |
T |
C |
4: 137,910,510 (GRCm39) |
L1330P |
possibly damaging |
Het |
| Eif4g3 |
T |
A |
4: 137,925,408 (GRCm39) |
S1584T |
probably benign |
Het |
| Enpp1 |
A |
T |
10: 24,555,146 (GRCm39) |
C67S |
probably null |
Het |
| Enpp5 |
C |
T |
17: 44,392,027 (GRCm39) |
T152I |
probably damaging |
Het |
| Erbb4 |
T |
C |
1: 68,383,059 (GRCm39) |
M313V |
probably damaging |
Het |
| Erc2 |
T |
G |
14: 27,498,838 (GRCm39) |
L238R |
probably damaging |
Het |
| Eya3 |
T |
A |
4: 132,448,698 (GRCm39) |
|
probably benign |
Het |
| Farp1 |
T |
C |
14: 121,476,199 (GRCm39) |
F339L |
probably damaging |
Het |
| Fsip2 |
A |
C |
2: 82,805,697 (GRCm39) |
D672A |
possibly damaging |
Het |
| Gap43 |
G |
T |
16: 42,112,581 (GRCm39) |
P60Q |
probably benign |
Het |
| Gpr37l1 |
T |
A |
1: 135,094,783 (GRCm39) |
I154F |
probably damaging |
Het |
| Greb1 |
A |
G |
12: 16,746,329 (GRCm39) |
S1314P |
probably damaging |
Het |
| Hectd4 |
A |
T |
5: 121,486,505 (GRCm39) |
M3167L |
probably benign |
Het |
| Hps3 |
C |
T |
3: 20,084,574 (GRCm39) |
|
probably null |
Het |
| Hps5 |
A |
G |
7: 46,436,013 (GRCm39) |
C178R |
probably benign |
Het |
| Hspg2 |
T |
A |
4: 137,297,384 (GRCm39) |
|
probably benign |
Het |
| Impdh2-ps |
A |
G |
8: 100,757,839 (GRCm39) |
|
noncoding transcript |
Het |
| Josd2 |
T |
A |
7: 44,120,678 (GRCm39) |
N138K |
probably damaging |
Het |
| Mtmr6 |
T |
G |
14: 60,529,546 (GRCm39) |
M315R |
probably damaging |
Het |
| Mtrf1 |
G |
A |
14: 79,650,520 (GRCm39) |
V323M |
probably damaging |
Het |
| Myo16 |
G |
T |
8: 10,423,527 (GRCm39) |
G288W |
probably damaging |
Het |
| Myo18a |
T |
C |
11: 77,714,149 (GRCm39) |
Y748H |
probably damaging |
Het |
| Nek1 |
A |
T |
8: 61,551,545 (GRCm39) |
N853I |
probably benign |
Het |
| Npnt |
T |
G |
3: 132,610,452 (GRCm39) |
T272P |
possibly damaging |
Het |
| Obi1 |
C |
T |
14: 104,747,819 (GRCm39) |
D43N |
probably damaging |
Het |
| Or2ag1b |
C |
A |
7: 106,288,351 (GRCm39) |
E196* |
probably null |
Het |
| Or2b6 |
T |
A |
13: 21,823,340 (GRCm39) |
M118L |
possibly damaging |
Het |
| Or2y17 |
G |
A |
11: 49,232,148 (GRCm39) |
G263D |
probably benign |
Het |
| Or51e1 |
T |
A |
7: 102,359,378 (GRCm39) |
I304N |
probably damaging |
Het |
| Or52n2c |
G |
A |
7: 104,574,017 (GRCm39) |
T318I |
possibly damaging |
Het |
| Or5a1 |
A |
G |
19: 12,097,234 (GRCm39) |
Y269H |
possibly damaging |
Het |
| Pappa2 |
T |
C |
1: 158,784,582 (GRCm39) |
R143G |
probably benign |
Het |
| Pappa2 |
T |
G |
1: 158,784,572 (GRCm39) |
D146A |
probably damaging |
Het |
| Pcsk9 |
C |
T |
4: 106,304,353 (GRCm39) |
G496R |
probably damaging |
Het |
| Pes1 |
A |
G |
11: 3,914,058 (GRCm39) |
K8E |
probably damaging |
Het |
| Phlpp2 |
G |
A |
8: 110,667,052 (GRCm39) |
G1194S |
probably damaging |
Het |
| Pkn1 |
A |
C |
8: 84,398,378 (GRCm39) |
V763G |
probably damaging |
Het |
| Pkp2 |
C |
A |
16: 16,048,588 (GRCm39) |
A331E |
probably damaging |
Het |
| Plb1 |
T |
A |
5: 32,507,023 (GRCm39) |
|
probably null |
Het |
| Polq |
C |
T |
16: 36,862,109 (GRCm39) |
T264M |
probably damaging |
Het |
| Prkag3 |
T |
C |
1: 74,779,864 (GRCm39) |
*490W |
probably null |
Het |
| Prl2c1 |
T |
C |
13: 28,041,661 (GRCm39) |
C228R |
probably damaging |
Het |
| Pus7l |
T |
C |
15: 94,438,591 (GRCm39) |
S85G |
probably benign |
Het |
| Rfc3 |
A |
C |
5: 151,568,241 (GRCm39) |
|
probably benign |
Het |
| Riox2 |
A |
G |
16: 59,309,732 (GRCm39) |
N362S |
probably benign |
Het |
| Scaper |
A |
T |
9: 55,650,932 (GRCm39) |
D904E |
probably damaging |
Het |
| Scn11a |
T |
C |
9: 119,583,627 (GRCm39) |
M1663V |
probably benign |
Het |
| Slc13a3 |
A |
T |
2: 165,272,209 (GRCm39) |
I278N |
possibly damaging |
Het |
| Slc22a7 |
T |
C |
17: 46,745,923 (GRCm39) |
E278G |
probably damaging |
Het |
| Snrnp48 |
T |
A |
13: 38,393,893 (GRCm39) |
M66K |
probably damaging |
Het |
| Styk1 |
T |
G |
6: 131,277,429 (GRCm39) |
E404A |
probably damaging |
Het |
| Synj1 |
T |
A |
16: 90,752,307 (GRCm39) |
H1016L |
probably benign |
Het |
| Tbc1d8 |
G |
A |
1: 39,441,959 (GRCm39) |
T211I |
possibly damaging |
Het |
| Tjp2 |
T |
C |
19: 24,097,475 (GRCm39) |
|
probably null |
Het |
| Tmem87a |
A |
G |
2: 120,190,518 (GRCm39) |
|
probably null |
Het |
| Trappc9 |
T |
G |
15: 72,808,909 (GRCm39) |
Y718S |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,641,587 (GRCm39) |
L5176Q |
possibly damaging |
Het |
| Ubqlnl |
C |
T |
7: 103,798,925 (GRCm39) |
V191M |
probably benign |
Het |
| Ugt2a3 |
C |
T |
5: 87,475,054 (GRCm39) |
G397R |
probably damaging |
Het |
| Wdr33 |
T |
A |
18: 32,019,139 (GRCm39) |
M454K |
probably benign |
Het |
| Wdtc1 |
G |
T |
4: 133,029,110 (GRCm39) |
N325K |
possibly damaging |
Het |
| Whrn |
T |
C |
4: 63,336,402 (GRCm39) |
H720R |
probably damaging |
Het |
| Xirp2 |
A |
T |
2: 67,349,609 (GRCm39) |
D3268V |
probably damaging |
Het |
| Zc3h7a |
A |
T |
16: 10,959,573 (GRCm39) |
H793Q |
probably damaging |
Het |
| Zfp518b |
C |
T |
5: 38,831,841 (GRCm39) |
A55T |
possibly damaging |
Het |
| Zmynd8 |
G |
A |
2: 165,647,249 (GRCm39) |
T901M |
probably damaging |
Het |
|
| Other mutations in Plxna1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00427:Plxna1
|
APN |
6 |
89,297,980 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01358:Plxna1
|
APN |
6 |
89,299,732 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01475:Plxna1
|
APN |
6 |
89,331,870 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL01480:Plxna1
|
APN |
6 |
89,321,078 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
IGL01585:Plxna1
|
APN |
6 |
89,306,538 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01804:Plxna1
|
APN |
6 |
89,306,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01909:Plxna1
|
APN |
6 |
89,309,066 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01989:Plxna1
|
APN |
6 |
89,306,396 (GRCm39) |
nonsense |
probably null |
|
|
IGL02015:Plxna1
|
APN |
6 |
89,319,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02023:Plxna1
|
APN |
6 |
89,334,314 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL02668:Plxna1
|
APN |
6 |
89,334,251 (GRCm39) |
nonsense |
probably null |
|
|
IGL02703:Plxna1
|
APN |
6 |
89,333,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02954:Plxna1
|
APN |
6 |
89,301,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03212:Plxna1
|
APN |
6 |
89,308,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4544001:Plxna1
|
UTSW |
6 |
89,334,411 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0055:Plxna1
|
UTSW |
6 |
89,306,721 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0055:Plxna1
|
UTSW |
6 |
89,306,721 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0147:Plxna1
|
UTSW |
6 |
89,297,692 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0149:Plxna1
|
UTSW |
6 |
89,297,595 (GRCm39) |
missense |
probably null |
0.95 |
|
R0166:Plxna1
|
UTSW |
6 |
89,310,001 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0200:Plxna1
|
UTSW |
6 |
89,300,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0415:Plxna1
|
UTSW |
6 |
89,334,318 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0841:Plxna1
|
UTSW |
6 |
89,309,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1018:Plxna1
|
UTSW |
6 |
89,319,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1240:Plxna1
|
UTSW |
6 |
89,298,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1355:Plxna1
|
UTSW |
6 |
89,297,748 (GRCm39) |
unclassified |
probably benign |
|
|
R1700:Plxna1
|
UTSW |
6 |
89,333,990 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1776:Plxna1
|
UTSW |
6 |
89,312,446 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1957:Plxna1
|
UTSW |
6 |
89,308,273 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2314:Plxna1
|
UTSW |
6 |
89,301,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2968:Plxna1
|
UTSW |
6 |
89,319,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3118:Plxna1
|
UTSW |
6 |
89,333,958 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3522:Plxna1
|
UTSW |
6 |
89,314,335 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3619:Plxna1
|
UTSW |
6 |
89,334,435 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3766:Plxna1
|
UTSW |
6 |
89,311,757 (GRCm39) |
unclassified |
probably benign |
|
|
R3847:Plxna1
|
UTSW |
6 |
89,333,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3849:Plxna1
|
UTSW |
6 |
89,333,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3872:Plxna1
|
UTSW |
6 |
89,309,674 (GRCm39) |
nonsense |
probably null |
|
|
R4555:Plxna1
|
UTSW |
6 |
89,300,310 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4709:Plxna1
|
UTSW |
6 |
89,311,733 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4726:Plxna1
|
UTSW |
6 |
89,299,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5053:Plxna1
|
UTSW |
6 |
89,299,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5221:Plxna1
|
UTSW |
6 |
89,297,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5449:Plxna1
|
UTSW |
6 |
89,300,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5480:Plxna1
|
UTSW |
6 |
89,301,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5575:Plxna1
|
UTSW |
6 |
89,301,523 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5743:Plxna1
|
UTSW |
6 |
89,333,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5744:Plxna1
|
UTSW |
6 |
89,311,664 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5754:Plxna1
|
UTSW |
6 |
89,310,087 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5868:Plxna1
|
UTSW |
6 |
89,299,704 (GRCm39) |
splice site |
probably benign |
|
|
R5988:Plxna1
|
UTSW |
6 |
89,334,522 (GRCm39) |
nonsense |
probably null |
|
|
R6190:Plxna1
|
UTSW |
6 |
89,333,586 (GRCm39) |
nonsense |
probably null |
|
|
R6425:Plxna1
|
UTSW |
6 |
89,311,647 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6561:Plxna1
|
UTSW |
6 |
89,333,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6623:Plxna1
|
UTSW |
6 |
89,299,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6638:Plxna1
|
UTSW |
6 |
89,301,382 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6701:Plxna1
|
UTSW |
6 |
89,296,430 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6825:Plxna1
|
UTSW |
6 |
89,297,597 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6911:Plxna1
|
UTSW |
6 |
89,297,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7073:Plxna1
|
UTSW |
6 |
89,334,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7177:Plxna1
|
UTSW |
6 |
89,300,311 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7235:Plxna1
|
UTSW |
6 |
89,317,573 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7419:Plxna1
|
UTSW |
6 |
89,334,584 (GRCm39) |
missense |
unknown |
|
|
R7511:Plxna1
|
UTSW |
6 |
89,318,889 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7543:Plxna1
|
UTSW |
6 |
89,299,837 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7665:Plxna1
|
UTSW |
6 |
89,301,520 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7678:Plxna1
|
UTSW |
6 |
89,308,882 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7748:Plxna1
|
UTSW |
6 |
89,314,335 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7748:Plxna1
|
UTSW |
6 |
89,314,334 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7877:Plxna1
|
UTSW |
6 |
89,300,241 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8025:Plxna1
|
UTSW |
6 |
89,308,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Plxna1
|
UTSW |
6 |
89,334,102 (GRCm39) |
missense |
probably benign |
0.20 |
|
R8277:Plxna1
|
UTSW |
6 |
89,334,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8782:Plxna1
|
UTSW |
6 |
89,300,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8867:Plxna1
|
UTSW |
6 |
89,310,079 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9245:Plxna1
|
UTSW |
6 |
89,314,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9253:Plxna1
|
UTSW |
6 |
89,334,522 (GRCm39) |
nonsense |
probably null |
|
|
R9269:Plxna1
|
UTSW |
6 |
89,306,541 (GRCm39) |
missense |
probably null |
1.00 |
|
R9273:Plxna1
|
UTSW |
6 |
89,296,364 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9281:Plxna1
|
UTSW |
6 |
89,300,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9368:Plxna1
|
UTSW |
6 |
89,314,138 (GRCm39) |
missense |
probably benign |
|
|
R9440:Plxna1
|
UTSW |
6 |
89,318,912 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9526:Plxna1
|
UTSW |
6 |
89,319,633 (GRCm39) |
missense |
probably benign |
|
|
R9601:Plxna1
|
UTSW |
6 |
89,308,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9714:Plxna1
|
UTSW |
6 |
89,296,440 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9782:Plxna1
|
UTSW |
6 |
89,333,817 (GRCm39) |
missense |
probably benign |
0.01 |
|
S24628:Plxna1
|
UTSW |
6 |
89,334,318 (GRCm39) |
missense |
probably benign |
0.12 |
|
V8831:Plxna1
|
UTSW |
6 |
89,334,119 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Plxna1
|
UTSW |
6 |
89,298,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGAGAGCTTGCTCAAGATGTC -3'
(R):5'- TCATGCAAGAAGAGACTGTGTC -3'
Sequencing Primer
(F):5'- GAGAGCTTGCTCAAGATGTCTATTC -3'
(R):5'- ACTGTGTCTCTTGTATGTCTAGGCC -3'
|
| Posted On |
2015-11-11 |
Incidental Mutation