Incidental Mutation 'R4739:Dip2c'
| ID |
359542 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dip2c
|
| Ensembl Gene |
ENSMUSG00000048264 |
| Gene Name |
disco interacting protein 2 homolog C |
| Synonyms |
2900024P20Rik |
| MMRRC Submission |
042025-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.711)
|
| Stock # |
R4739 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
9276528-9668928 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 9533339 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Glutamine
at position 119
(L119Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133806
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000166299]
[ENSMUST00000169960]
[ENSMUST00000174552]
|
| AlphaFold |
E9PWR4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000166299
AA Change: L119Q
PolyPhen 2
Score 0.984 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000126827
Gene: ENSMUSG00000048264
AA Change: L119Q
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
120 |
3.55e-43 |
SMART |
|
low complexity region
|
170 |
187 |
N/A |
INTRINSIC |
|
low complexity region
|
275 |
287 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
324 |
801 |
3.6e-23 |
PFAM |
|
Pfam:AMP-binding
|
977 |
1451 |
1.5e-72 |
PFAM |
|
low complexity region
|
1514 |
1526 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000169960
AA Change: L175Q
|
| SMART Domains |
Protein: ENSMUSP00000131238
Gene: ENSMUSG00000048264
AA Change: L175Q
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
176 |
3.02e-37 |
SMART |
|
low complexity region
|
226 |
243 |
N/A |
INTRINSIC |
|
low complexity region
|
331 |
343 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
380 |
637 |
5.9e-10 |
PFAM |
|
SCOP:d1lci__
|
675 |
875 |
2e-8 |
SMART |
|
Pfam:AMP-binding
|
947 |
1421 |
1.2e-56 |
PFAM |
|
low complexity region
|
1484 |
1496 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000174552
AA Change: L119Q
PolyPhen 2
Score 0.984 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000133806
Gene: ENSMUSG00000048264
AA Change: L119Q
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
120 |
3.55e-43 |
SMART |
|
low complexity region
|
170 |
187 |
N/A |
INTRINSIC |
|
low complexity region
|
275 |
287 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
324 |
800 |
2.7e-20 |
PFAM |
|
Pfam:AMP-binding
|
976 |
1450 |
1.3e-56 |
PFAM |
|
low complexity region
|
1513 |
1525 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1515 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.5%
|
| Validation Efficiency |
96% (102/106) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the disco-interacting protein homolog 2 family. The protein shares strong similarity with a Drosophila protein which interacts with the transcription factor disco and is expressed in the nervous system. [provided by RefSeq, Oct 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1600012P17Rik |
C |
T |
1: 158,969,334 |
|
noncoding transcript |
Het |
| 2300002M23Rik |
A |
G |
17: 35,567,506 |
|
probably benign |
Het |
| Aadat |
T |
C |
8: 60,540,106 |
V360A |
probably benign |
Het |
| Abcc5 |
T |
A |
16: 20,399,626 |
D283V |
probably damaging |
Het |
| Abraxas1 |
T |
A |
5: 100,812,020 |
K155N |
probably damaging |
Het |
| Acot3 |
T |
C |
12: 84,058,590 |
I277T |
probably benign |
Het |
| Ankrd45 |
G |
A |
1: 161,155,390 |
C157Y |
probably damaging |
Het |
| Apol10a |
C |
T |
15: 77,488,641 |
T159I |
possibly damaging |
Het |
| Arhgef11 |
G |
A |
3: 87,697,999 |
V214M |
possibly damaging |
Het |
| Ash1l |
A |
C |
3: 88,982,845 |
N677T |
probably benign |
Het |
| Atg13 |
A |
G |
2: 91,684,695 |
S254P |
probably damaging |
Het |
| Atg16l2 |
A |
G |
7: 101,297,178 |
L129P |
probably damaging |
Het |
| Avl9 |
T |
A |
6: 56,726,309 |
V120D |
probably damaging |
Het |
| Cc2d1b |
T |
C |
4: 108,628,042 |
V527A |
probably benign |
Het |
| Ccnl1 |
A |
G |
3: 65,946,671 |
|
probably benign |
Het |
| Cenpl |
T |
A |
1: 161,083,267 |
D261E |
probably damaging |
Het |
| Cep192 |
T |
G |
18: 67,851,732 |
I1604M |
probably benign |
Het |
| Cep95 |
A |
G |
11: 106,815,734 |
I573V |
probably benign |
Het |
| Cfap100 |
A |
G |
6: 90,412,843 |
|
probably null |
Het |
| Cmc1 |
T |
A |
9: 118,075,177 |
M49L |
probably benign |
Het |
| Cyfip2 |
G |
T |
11: 46,279,993 |
N176K |
probably damaging |
Het |
| Cyp2w1 |
T |
C |
5: 139,356,675 |
F408L |
probably damaging |
Het |
| D630045J12Rik |
G |
A |
6: 38,196,036 |
S399F |
possibly damaging |
Het |
| Dcbld2 |
T |
A |
16: 58,460,976 |
L528Q |
probably damaging |
Het |
| Dip2b |
T |
C |
15: 100,207,777 |
V1138A |
probably damaging |
Het |
| Dnah3 |
T |
C |
7: 120,077,946 |
D444G |
possibly damaging |
Het |
| Dsg1c |
A |
T |
18: 20,275,189 |
N432Y |
possibly damaging |
Het |
| Dst |
T |
A |
1: 34,191,147 |
I2785N |
probably benign |
Het |
| Dynap |
A |
T |
18: 70,241,225 |
Y77N |
possibly damaging |
Het |
| Eif4g3 |
T |
C |
4: 138,183,199 |
L1330P |
possibly damaging |
Het |
| Eif4g3 |
T |
A |
4: 138,198,097 |
S1584T |
probably benign |
Het |
| Enpp1 |
A |
T |
10: 24,679,248 |
C67S |
probably null |
Het |
| Enpp5 |
C |
T |
17: 44,081,136 |
T152I |
probably damaging |
Het |
| Erbb4 |
T |
C |
1: 68,343,900 |
M313V |
probably damaging |
Het |
| Erc2 |
T |
G |
14: 27,776,881 |
L238R |
probably damaging |
Het |
| Eya3 |
T |
A |
4: 132,721,387 |
|
probably benign |
Het |
| Farp1 |
T |
C |
14: 121,238,787 |
F339L |
probably damaging |
Het |
| Fsip2 |
A |
C |
2: 82,975,353 |
D672A |
possibly damaging |
Het |
| Gap43 |
G |
T |
16: 42,292,218 |
P60Q |
probably benign |
Het |
| Gatsl3 |
A |
G |
11: 4,219,004 |
E57G |
possibly damaging |
Het |
| Gpr37l1 |
T |
A |
1: 135,167,045 |
I154F |
probably damaging |
Het |
| Greb1 |
A |
G |
12: 16,696,328 |
S1314P |
probably damaging |
Het |
| Hectd4 |
A |
T |
5: 121,348,442 |
M3167L |
probably benign |
Het |
| Hps3 |
C |
T |
3: 20,030,410 |
|
probably null |
Het |
| Hps5 |
A |
G |
7: 46,786,589 |
C178R |
probably benign |
Het |
| Hspg2 |
T |
A |
4: 137,570,073 |
|
probably benign |
Het |
| Impdh2-ps |
A |
G |
8: 100,031,207 |
|
noncoding transcript |
Het |
| Josd2 |
T |
A |
7: 44,471,254 |
N138K |
probably damaging |
Het |
| Mtmr6 |
T |
G |
14: 60,292,097 |
M315R |
probably damaging |
Het |
| Mtrf1 |
G |
A |
14: 79,413,080 |
V323M |
probably damaging |
Het |
| Myo16 |
G |
T |
8: 10,373,527 |
G288W |
probably damaging |
Het |
| Myo18a |
T |
C |
11: 77,823,323 |
Y748H |
probably damaging |
Het |
| Narfl |
A |
T |
17: 25,781,309 |
H322L |
probably damaging |
Het |
| Nek1 |
A |
T |
8: 61,098,511 |
N853I |
probably benign |
Het |
| Npnt |
T |
G |
3: 132,904,691 |
T272P |
possibly damaging |
Het |
| Olfr11 |
T |
A |
13: 21,639,170 |
M118L |
possibly damaging |
Het |
| Olfr1390 |
G |
A |
11: 49,341,321 |
G263D |
probably benign |
Het |
| Olfr558 |
T |
A |
7: 102,710,171 |
I304N |
probably damaging |
Het |
| Olfr668 |
G |
A |
7: 104,924,810 |
T318I |
possibly damaging |
Het |
| Olfr694 |
C |
A |
7: 106,689,144 |
E196* |
probably null |
Het |
| Olfr76 |
A |
G |
19: 12,119,870 |
Y269H |
possibly damaging |
Het |
| Pappa2 |
T |
G |
1: 158,957,002 |
D146A |
probably damaging |
Het |
| Pappa2 |
T |
C |
1: 158,957,012 |
R143G |
probably benign |
Het |
| Pcsk9 |
C |
T |
4: 106,447,156 |
G496R |
probably damaging |
Het |
| Pes1 |
A |
G |
11: 3,964,058 |
K8E |
probably damaging |
Het |
| Phlpp2 |
G |
A |
8: 109,940,420 |
G1194S |
probably damaging |
Het |
| Pkn1 |
A |
C |
8: 83,671,749 |
V763G |
probably damaging |
Het |
| Pkp2 |
C |
A |
16: 16,230,724 |
A331E |
probably damaging |
Het |
| Plb1 |
T |
A |
5: 32,349,679 |
|
probably null |
Het |
| Plxna1 |
A |
T |
6: 89,332,675 |
|
probably null |
Het |
| Polq |
C |
T |
16: 37,041,747 |
T264M |
probably damaging |
Het |
| Prkag3 |
T |
C |
1: 74,740,705 |
*490W |
probably null |
Het |
| Prl2c1 |
T |
C |
13: 27,857,678 |
C228R |
probably damaging |
Het |
| Pus7l |
T |
C |
15: 94,540,710 |
S85G |
probably benign |
Het |
| Rfc3 |
A |
C |
5: 151,644,776 |
|
probably benign |
Het |
| Riox2 |
A |
G |
16: 59,489,369 |
N362S |
probably benign |
Het |
| Rnf219 |
C |
T |
14: 104,510,383 |
D43N |
probably damaging |
Het |
| Scaper |
A |
T |
9: 55,743,648 |
D904E |
probably damaging |
Het |
| Scn11a |
T |
C |
9: 119,754,561 |
M1663V |
probably benign |
Het |
| Slc13a3 |
A |
T |
2: 165,430,289 |
I278N |
possibly damaging |
Het |
| Slc22a7 |
T |
C |
17: 46,434,997 |
E278G |
probably damaging |
Het |
| Snrnp48 |
T |
A |
13: 38,209,917 |
M66K |
probably damaging |
Het |
| Styk1 |
T |
G |
6: 131,300,466 |
E404A |
probably damaging |
Het |
| Synj1 |
T |
A |
16: 90,955,419 |
H1016L |
probably benign |
Het |
| Tbc1d8 |
G |
A |
1: 39,402,878 |
T211I |
possibly damaging |
Het |
| Tjp2 |
T |
C |
19: 24,120,111 |
|
probably null |
Het |
| Tmem87a |
A |
G |
2: 120,360,037 |
|
probably null |
Het |
| Trappc9 |
T |
G |
15: 72,937,060 |
Y718S |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,811,243 |
L5176Q |
possibly damaging |
Het |
| Ubqlnl |
C |
T |
7: 104,149,718 |
V191M |
probably benign |
Het |
| Ugt2a3 |
C |
T |
5: 87,327,195 |
G397R |
probably damaging |
Het |
| Wdr33 |
T |
A |
18: 31,886,086 |
M454K |
probably benign |
Het |
| Wdtc1 |
G |
T |
4: 133,301,799 |
N325K |
possibly damaging |
Het |
| Whrn |
T |
C |
4: 63,418,165 |
H720R |
probably damaging |
Het |
| Xirp2 |
A |
T |
2: 67,519,265 |
D3268V |
probably damaging |
Het |
| Zc3h7a |
A |
T |
16: 11,141,709 |
H793Q |
probably damaging |
Het |
| Zfp518b |
C |
T |
5: 38,674,498 |
A55T |
possibly damaging |
Het |
| Zmynd8 |
G |
A |
2: 165,805,329 |
T901M |
probably damaging |
Het |
|
| Other mutations in Dip2c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00392:Dip2c
|
APN |
13 |
9,493,108 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL00426:Dip2c
|
APN |
13 |
9,606,515 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00503:Dip2c
|
APN |
13 |
9,567,898 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00586:Dip2c
|
APN |
13 |
9,610,755 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01306:Dip2c
|
APN |
13 |
9,575,143 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
IGL01580:Dip2c
|
APN |
13 |
9,637,088 (GRCm38) |
splice site |
probably null |
|
|
IGL01985:Dip2c
|
APN |
13 |
9,553,267 (GRCm38) |
splice site |
probably benign |
|
|
IGL02060:Dip2c
|
APN |
13 |
9,622,630 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL02122:Dip2c
|
APN |
13 |
9,506,659 (GRCm38) |
missense |
possibly damaging |
0.48 |
|
IGL02170:Dip2c
|
APN |
13 |
9,606,335 (GRCm38) |
missense |
probably benign |
0.03 |
|
IGL02211:Dip2c
|
APN |
13 |
9,610,847 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02755:Dip2c
|
APN |
13 |
9,550,320 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02836:Dip2c
|
APN |
13 |
9,610,790 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL02935:Dip2c
|
APN |
13 |
9,662,146 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03032:Dip2c
|
APN |
13 |
9,551,778 (GRCm38) |
missense |
probably damaging |
1.00 |
|
ANU23:Dip2c
|
UTSW |
13 |
9,575,143 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
P0038:Dip2c
|
UTSW |
13 |
9,646,982 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0009:Dip2c
|
UTSW |
13 |
9,621,903 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0268:Dip2c
|
UTSW |
13 |
9,637,150 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0271:Dip2c
|
UTSW |
13 |
9,615,775 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0306:Dip2c
|
UTSW |
13 |
9,604,599 (GRCm38) |
missense |
probably benign |
0.09 |
|
R0415:Dip2c
|
UTSW |
13 |
9,568,289 (GRCm38) |
splice site |
probably benign |
|
|
R0519:Dip2c
|
UTSW |
13 |
9,563,208 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0557:Dip2c
|
UTSW |
13 |
9,553,459 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R0964:Dip2c
|
UTSW |
13 |
9,568,663 (GRCm38) |
missense |
probably benign |
0.43 |
|
R0973:Dip2c
|
UTSW |
13 |
9,576,908 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0973:Dip2c
|
UTSW |
13 |
9,576,908 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0974:Dip2c
|
UTSW |
13 |
9,576,908 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1101:Dip2c
|
UTSW |
13 |
9,634,744 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1171:Dip2c
|
UTSW |
13 |
9,493,126 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R1403:Dip2c
|
UTSW |
13 |
9,553,264 (GRCm38) |
splice site |
probably null |
|
|
R1403:Dip2c
|
UTSW |
13 |
9,553,264 (GRCm38) |
splice site |
probably null |
|
|
R1432:Dip2c
|
UTSW |
13 |
9,553,304 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1481:Dip2c
|
UTSW |
13 |
9,551,866 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1588:Dip2c
|
UTSW |
13 |
9,665,864 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1721:Dip2c
|
UTSW |
13 |
9,659,368 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1726:Dip2c
|
UTSW |
13 |
9,575,428 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1867:Dip2c
|
UTSW |
13 |
9,621,949 (GRCm38) |
missense |
possibly damaging |
0.55 |
|
R1909:Dip2c
|
UTSW |
13 |
9,533,350 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2013:Dip2c
|
UTSW |
13 |
9,567,846 (GRCm38) |
nonsense |
probably null |
|
|
R2022:Dip2c
|
UTSW |
13 |
9,551,800 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2517:Dip2c
|
UTSW |
13 |
9,609,005 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3746:Dip2c
|
UTSW |
13 |
9,601,473 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3794:Dip2c
|
UTSW |
13 |
9,604,561 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R3884:Dip2c
|
UTSW |
13 |
9,551,858 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4019:Dip2c
|
UTSW |
13 |
9,614,365 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4110:Dip2c
|
UTSW |
13 |
9,637,101 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4111:Dip2c
|
UTSW |
13 |
9,637,101 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4113:Dip2c
|
UTSW |
13 |
9,637,101 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4256:Dip2c
|
UTSW |
13 |
9,609,056 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4300:Dip2c
|
UTSW |
13 |
9,610,711 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4494:Dip2c
|
UTSW |
13 |
9,571,062 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R4812:Dip2c
|
UTSW |
13 |
9,637,130 (GRCm38) |
nonsense |
probably null |
|
|
R4814:Dip2c
|
UTSW |
13 |
9,536,860 (GRCm38) |
missense |
probably benign |
0.07 |
|
R4816:Dip2c
|
UTSW |
13 |
9,575,150 (GRCm38) |
missense |
probably benign |
0.37 |
|
R4828:Dip2c
|
UTSW |
13 |
9,560,679 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4915:Dip2c
|
UTSW |
13 |
9,621,869 (GRCm38) |
splice site |
probably null |
|
|
R4917:Dip2c
|
UTSW |
13 |
9,621,869 (GRCm38) |
splice site |
probably null |
|
|
R4932:Dip2c
|
UTSW |
13 |
9,623,972 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4993:Dip2c
|
UTSW |
13 |
9,575,223 (GRCm38) |
nonsense |
probably null |
|
|
R5043:Dip2c
|
UTSW |
13 |
9,551,827 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R5349:Dip2c
|
UTSW |
13 |
9,622,653 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5744:Dip2c
|
UTSW |
13 |
9,568,405 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5840:Dip2c
|
UTSW |
13 |
9,506,676 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R6110:Dip2c
|
UTSW |
13 |
9,623,766 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6160:Dip2c
|
UTSW |
13 |
9,533,254 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6161:Dip2c
|
UTSW |
13 |
9,647,007 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6477:Dip2c
|
UTSW |
13 |
9,623,760 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6522:Dip2c
|
UTSW |
13 |
9,575,228 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6603:Dip2c
|
UTSW |
13 |
9,654,588 (GRCm38) |
splice site |
probably null |
|
|
R6658:Dip2c
|
UTSW |
13 |
9,493,177 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6672:Dip2c
|
UTSW |
13 |
9,567,830 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R6697:Dip2c
|
UTSW |
13 |
9,621,913 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6991:Dip2c
|
UTSW |
13 |
9,634,832 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6991:Dip2c
|
UTSW |
13 |
9,551,860 (GRCm38) |
nonsense |
probably null |
|
|
R7018:Dip2c
|
UTSW |
13 |
9,659,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7053:Dip2c
|
UTSW |
13 |
9,610,704 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7102:Dip2c
|
UTSW |
13 |
9,604,536 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7171:Dip2c
|
UTSW |
13 |
9,506,648 (GRCm38) |
missense |
probably benign |
0.34 |
|
R7371:Dip2c
|
UTSW |
13 |
9,592,749 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7395:Dip2c
|
UTSW |
13 |
9,614,377 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7489:Dip2c
|
UTSW |
13 |
9,533,312 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7575:Dip2c
|
UTSW |
13 |
9,628,012 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R7642:Dip2c
|
UTSW |
13 |
9,622,705 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7687:Dip2c
|
UTSW |
13 |
9,604,581 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7699:Dip2c
|
UTSW |
13 |
9,659,311 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7700:Dip2c
|
UTSW |
13 |
9,659,311 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7715:Dip2c
|
UTSW |
13 |
9,614,391 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7842:Dip2c
|
UTSW |
13 |
9,606,533 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7845:Dip2c
|
UTSW |
13 |
9,609,044 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8354:Dip2c
|
UTSW |
13 |
9,621,882 (GRCm38) |
missense |
probably benign |
0.05 |
|
R8685:Dip2c
|
UTSW |
13 |
9,637,125 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8779:Dip2c
|
UTSW |
13 |
9,610,809 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8786:Dip2c
|
UTSW |
13 |
9,615,794 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8815:Dip2c
|
UTSW |
13 |
9,623,798 (GRCm38) |
nonsense |
probably null |
|
|
R8833:Dip2c
|
UTSW |
13 |
9,575,483 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8868:Dip2c
|
UTSW |
13 |
9,575,467 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R8873:Dip2c
|
UTSW |
13 |
9,575,146 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8887:Dip2c
|
UTSW |
13 |
9,623,953 (GRCm38) |
splice site |
probably benign |
|
|
R8923:Dip2c
|
UTSW |
13 |
9,623,865 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9112:Dip2c
|
UTSW |
13 |
9,610,730 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9424:Dip2c
|
UTSW |
13 |
9,659,395 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9474:Dip2c
|
UTSW |
13 |
9,494,927 (GRCm38) |
missense |
unknown |
|
|
R9527:Dip2c
|
UTSW |
13 |
9,494,839 (GRCm38) |
missense |
unknown |
|
|
R9593:Dip2c
|
UTSW |
13 |
9,654,647 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R9615:Dip2c
|
UTSW |
13 |
9,575,155 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9801:Dip2c
|
UTSW |
13 |
9,576,900 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGTAGAACGACTGCTTTCC -3'
(R):5'- GCAAATGCTGTGATTGAAAGC -3'
Sequencing Primer
(F):5'- TCTGAGCTTAGGTACAAAGTCC -3'
(R):5'- TGCTGTGATTGAAAGCCATATTG -3'
|
| Posted On |
2015-11-11 |
Incidental Mutation