Incidental Mutation 'R4739:Dip2b'
| ID |
359554 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dip2b
|
| Ensembl Gene |
ENSMUSG00000023026 |
| Gene Name |
disco interacting protein 2 homolog B |
| Synonyms |
|
| MMRRC Submission |
042025-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.596)
|
| Stock # |
R4739 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
100038664-100219473 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 100207777 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1138
(V1138A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000023768
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000023768]
[ENSMUST00000100203]
[ENSMUST00000108971]
|
| AlphaFold |
Q3UH60 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000023768
AA Change: V1138A
PolyPhen 2
Score 0.981 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000023768
Gene: ENSMUSG00000023026
AA Change: V1138A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AMP-binding
|
109 |
584 |
9.5e-26 |
PFAM |
|
Pfam:AMP-binding
|
760 |
1235 |
1.2e-52 |
PFAM |
|
low complexity region
|
1299 |
1311 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000100203
AA Change: V1372A
PolyPhen 2
Score 0.948 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000097777
Gene: ENSMUSG00000023026
AA Change: V1372A
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
12 |
130 |
1e-42 |
SMART |
|
low complexity region
|
152 |
168 |
N/A |
INTRINSIC |
|
low complexity region
|
181 |
192 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
341 |
817 |
2e-26 |
PFAM |
|
Pfam:AMP-binding
|
993 |
1468 |
1.8e-64 |
PFAM |
|
low complexity region
|
1532 |
1544 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108971
AA Change: V1138A
PolyPhen 2
Score 0.981 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000104599
Gene: ENSMUSG00000023026
AA Change: V1138A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AMP-binding
|
108 |
583 |
9.5e-26 |
PFAM |
|
Pfam:AMP-binding
|
759 |
1234 |
1.2e-52 |
PFAM |
|
low complexity region
|
1298 |
1310 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135658
|
| Meta Mutation Damage Score |
0.5980 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.5%
|
| Validation Efficiency |
96% (102/106) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12. [provided by RefSeq, Aug 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1600012P17Rik |
C |
T |
1: 158,969,334 (GRCm38) |
|
noncoding transcript |
Het |
| 2300002M23Rik |
A |
G |
17: 35,567,506 (GRCm38) |
|
probably benign |
Het |
| Aadat |
T |
C |
8: 60,540,106 (GRCm38) |
V360A |
probably benign |
Het |
| Abcc5 |
T |
A |
16: 20,399,626 (GRCm38) |
D283V |
probably damaging |
Het |
| Abraxas1 |
T |
A |
5: 100,812,020 (GRCm38) |
K155N |
probably damaging |
Het |
| Acot3 |
T |
C |
12: 84,058,590 (GRCm38) |
I277T |
probably benign |
Het |
| Ankrd45 |
G |
A |
1: 161,155,390 (GRCm38) |
C157Y |
probably damaging |
Het |
| Apol10a |
C |
T |
15: 77,488,641 (GRCm38) |
T159I |
possibly damaging |
Het |
| Arhgef11 |
G |
A |
3: 87,697,999 (GRCm38) |
V214M |
possibly damaging |
Het |
| Ash1l |
A |
C |
3: 88,982,845 (GRCm38) |
N677T |
probably benign |
Het |
| Atg13 |
A |
G |
2: 91,684,695 (GRCm38) |
S254P |
probably damaging |
Het |
| Atg16l2 |
A |
G |
7: 101,297,178 (GRCm38) |
L129P |
probably damaging |
Het |
| Avl9 |
T |
A |
6: 56,726,309 (GRCm38) |
V120D |
probably damaging |
Het |
| Cc2d1b |
T |
C |
4: 108,628,042 (GRCm38) |
V527A |
probably benign |
Het |
| Ccnl1 |
A |
G |
3: 65,946,671 (GRCm38) |
|
probably benign |
Het |
| Cenpl |
T |
A |
1: 161,083,267 (GRCm38) |
D261E |
probably damaging |
Het |
| Cep192 |
T |
G |
18: 67,851,732 (GRCm38) |
I1604M |
probably benign |
Het |
| Cep95 |
A |
G |
11: 106,815,734 (GRCm38) |
I573V |
probably benign |
Het |
| Cfap100 |
A |
G |
6: 90,412,843 (GRCm38) |
|
probably null |
Het |
| Cmc1 |
T |
A |
9: 118,075,177 (GRCm38) |
M49L |
probably benign |
Het |
| Cyfip2 |
G |
T |
11: 46,279,993 (GRCm38) |
N176K |
probably damaging |
Het |
| Cyp2w1 |
T |
C |
5: 139,356,675 (GRCm38) |
F408L |
probably damaging |
Het |
| D630045J12Rik |
G |
A |
6: 38,196,036 (GRCm38) |
S399F |
possibly damaging |
Het |
| Dcbld2 |
T |
A |
16: 58,460,976 (GRCm38) |
L528Q |
probably damaging |
Het |
| Dip2c |
T |
A |
13: 9,533,339 (GRCm38) |
L119Q |
probably damaging |
Het |
| Dnah3 |
T |
C |
7: 120,077,946 (GRCm38) |
D444G |
possibly damaging |
Het |
| Dsg1c |
A |
T |
18: 20,275,189 (GRCm38) |
N432Y |
possibly damaging |
Het |
| Dst |
T |
A |
1: 34,191,147 (GRCm38) |
I2785N |
probably benign |
Het |
| Dynap |
A |
T |
18: 70,241,225 (GRCm38) |
Y77N |
possibly damaging |
Het |
| Eif4g3 |
T |
C |
4: 138,183,199 (GRCm38) |
L1330P |
possibly damaging |
Het |
| Eif4g3 |
T |
A |
4: 138,198,097 (GRCm38) |
S1584T |
probably benign |
Het |
| Enpp1 |
A |
T |
10: 24,679,248 (GRCm38) |
C67S |
probably null |
Het |
| Enpp5 |
C |
T |
17: 44,081,136 (GRCm38) |
T152I |
probably damaging |
Het |
| Erbb4 |
T |
C |
1: 68,343,900 (GRCm38) |
M313V |
probably damaging |
Het |
| Erc2 |
T |
G |
14: 27,776,881 (GRCm38) |
L238R |
probably damaging |
Het |
| Eya3 |
T |
A |
4: 132,721,387 (GRCm38) |
|
probably benign |
Het |
| Farp1 |
T |
C |
14: 121,238,787 (GRCm38) |
F339L |
probably damaging |
Het |
| Fsip2 |
A |
C |
2: 82,975,353 (GRCm38) |
D672A |
possibly damaging |
Het |
| Gap43 |
G |
T |
16: 42,292,218 (GRCm38) |
P60Q |
probably benign |
Het |
| Gatsl3 |
A |
G |
11: 4,219,004 (GRCm38) |
E57G |
possibly damaging |
Het |
| Gpr37l1 |
T |
A |
1: 135,167,045 (GRCm38) |
I154F |
probably damaging |
Het |
| Greb1 |
A |
G |
12: 16,696,328 (GRCm38) |
S1314P |
probably damaging |
Het |
| Hectd4 |
A |
T |
5: 121,348,442 (GRCm38) |
M3167L |
probably benign |
Het |
| Hps3 |
C |
T |
3: 20,030,410 (GRCm38) |
|
probably null |
Het |
| Hps5 |
A |
G |
7: 46,786,589 (GRCm38) |
C178R |
probably benign |
Het |
| Hspg2 |
T |
A |
4: 137,570,073 (GRCm38) |
|
probably benign |
Het |
| Impdh2-ps |
A |
G |
8: 100,031,207 (GRCm38) |
|
noncoding transcript |
Het |
| Josd2 |
T |
A |
7: 44,471,254 (GRCm38) |
N138K |
probably damaging |
Het |
| Mtmr6 |
T |
G |
14: 60,292,097 (GRCm38) |
M315R |
probably damaging |
Het |
| Mtrf1 |
G |
A |
14: 79,413,080 (GRCm38) |
V323M |
probably damaging |
Het |
| Myo16 |
G |
T |
8: 10,373,527 (GRCm38) |
G288W |
probably damaging |
Het |
| Myo18a |
T |
C |
11: 77,823,323 (GRCm38) |
Y748H |
probably damaging |
Het |
| Narfl |
A |
T |
17: 25,781,309 (GRCm38) |
H322L |
probably damaging |
Het |
| Nek1 |
A |
T |
8: 61,098,511 (GRCm38) |
N853I |
probably benign |
Het |
| Npnt |
T |
G |
3: 132,904,691 (GRCm38) |
T272P |
possibly damaging |
Het |
| Olfr11 |
T |
A |
13: 21,639,170 (GRCm38) |
M118L |
possibly damaging |
Het |
| Olfr1390 |
G |
A |
11: 49,341,321 (GRCm38) |
G263D |
probably benign |
Het |
| Olfr558 |
T |
A |
7: 102,710,171 (GRCm38) |
I304N |
probably damaging |
Het |
| Olfr668 |
G |
A |
7: 104,924,810 (GRCm38) |
T318I |
possibly damaging |
Het |
| Olfr694 |
C |
A |
7: 106,689,144 (GRCm38) |
E196* |
probably null |
Het |
| Olfr76 |
A |
G |
19: 12,119,870 (GRCm38) |
Y269H |
possibly damaging |
Het |
| Pappa2 |
T |
C |
1: 158,957,012 (GRCm38) |
R143G |
probably benign |
Het |
| Pappa2 |
T |
G |
1: 158,957,002 (GRCm38) |
D146A |
probably damaging |
Het |
| Pcsk9 |
C |
T |
4: 106,447,156 (GRCm38) |
G496R |
probably damaging |
Het |
| Pes1 |
A |
G |
11: 3,964,058 (GRCm38) |
K8E |
probably damaging |
Het |
| Phlpp2 |
G |
A |
8: 109,940,420 (GRCm38) |
G1194S |
probably damaging |
Het |
| Pkn1 |
A |
C |
8: 83,671,749 (GRCm38) |
V763G |
probably damaging |
Het |
| Pkp2 |
C |
A |
16: 16,230,724 (GRCm38) |
A331E |
probably damaging |
Het |
| Plb1 |
T |
A |
5: 32,349,679 (GRCm38) |
|
probably null |
Het |
| Plxna1 |
A |
T |
6: 89,332,675 (GRCm38) |
|
probably null |
Het |
| Polq |
C |
T |
16: 37,041,747 (GRCm38) |
T264M |
probably damaging |
Het |
| Prkag3 |
T |
C |
1: 74,740,705 (GRCm38) |
*490W |
probably null |
Het |
| Prl2c1 |
T |
C |
13: 27,857,678 (GRCm38) |
C228R |
probably damaging |
Het |
| Pus7l |
T |
C |
15: 94,540,710 (GRCm38) |
S85G |
probably benign |
Het |
| Rfc3 |
A |
C |
5: 151,644,776 (GRCm38) |
|
probably benign |
Het |
| Riox2 |
A |
G |
16: 59,489,369 (GRCm38) |
N362S |
probably benign |
Het |
| Rnf219 |
C |
T |
14: 104,510,383 (GRCm38) |
D43N |
probably damaging |
Het |
| Scaper |
A |
T |
9: 55,743,648 (GRCm38) |
D904E |
probably damaging |
Het |
| Scn11a |
T |
C |
9: 119,754,561 (GRCm38) |
M1663V |
probably benign |
Het |
| Slc13a3 |
A |
T |
2: 165,430,289 (GRCm38) |
I278N |
possibly damaging |
Het |
| Slc22a7 |
T |
C |
17: 46,434,997 (GRCm38) |
E278G |
probably damaging |
Het |
| Snrnp48 |
T |
A |
13: 38,209,917 (GRCm38) |
M66K |
probably damaging |
Het |
| Styk1 |
T |
G |
6: 131,300,466 (GRCm38) |
E404A |
probably damaging |
Het |
| Synj1 |
T |
A |
16: 90,955,419 (GRCm38) |
H1016L |
probably benign |
Het |
| Tbc1d8 |
G |
A |
1: 39,402,878 (GRCm38) |
T211I |
possibly damaging |
Het |
| Tjp2 |
T |
C |
19: 24,120,111 (GRCm38) |
|
probably null |
Het |
| Tmem87a |
A |
G |
2: 120,360,037 (GRCm38) |
|
probably null |
Het |
| Trappc9 |
T |
G |
15: 72,937,060 (GRCm38) |
Y718S |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,811,243 (GRCm38) |
L5176Q |
possibly damaging |
Het |
| Ubqlnl |
C |
T |
7: 104,149,718 (GRCm38) |
V191M |
probably benign |
Het |
| Ugt2a3 |
C |
T |
5: 87,327,195 (GRCm38) |
G397R |
probably damaging |
Het |
| Wdr33 |
T |
A |
18: 31,886,086 (GRCm38) |
M454K |
probably benign |
Het |
| Wdtc1 |
G |
T |
4: 133,301,799 (GRCm38) |
N325K |
possibly damaging |
Het |
| Whrn |
T |
C |
4: 63,418,165 (GRCm38) |
H720R |
probably damaging |
Het |
| Xirp2 |
A |
T |
2: 67,519,265 (GRCm38) |
D3268V |
probably damaging |
Het |
| Zc3h7a |
A |
T |
16: 11,141,709 (GRCm38) |
H793Q |
probably damaging |
Het |
| Zfp518b |
C |
T |
5: 38,674,498 (GRCm38) |
A55T |
possibly damaging |
Het |
| Zmynd8 |
G |
A |
2: 165,805,329 (GRCm38) |
T901M |
probably damaging |
Het |
|
| Other mutations in Dip2b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00515:Dip2b
|
APN |
15 |
100,174,501 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01716:Dip2b
|
APN |
15 |
100,209,636 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01893:Dip2b
|
APN |
15 |
100,171,220 (GRCm38) |
splice site |
probably benign |
|
|
IGL01915:Dip2b
|
APN |
15 |
100,178,511 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02125:Dip2b
|
APN |
15 |
100,186,250 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
IGL02200:Dip2b
|
APN |
15 |
100,151,202 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL02506:Dip2b
|
APN |
15 |
100,157,281 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02571:Dip2b
|
APN |
15 |
100,157,885 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL02706:Dip2b
|
APN |
15 |
100,215,311 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL02983:Dip2b
|
APN |
15 |
100,132,022 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
IGL03120:Dip2b
|
APN |
15 |
100,203,127 (GRCm38) |
splice site |
probably benign |
|
|
IGL03181:Dip2b
|
APN |
15 |
100,215,207 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL03229:Dip2b
|
APN |
15 |
100,207,838 (GRCm38) |
splice site |
probably benign |
|
|
IGL03399:Dip2b
|
APN |
15 |
100,175,327 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
PIT4131001:Dip2b
|
UTSW |
15 |
100,202,352 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0009:Dip2b
|
UTSW |
15 |
100,169,312 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0058:Dip2b
|
UTSW |
15 |
100,215,240 (GRCm38) |
missense |
probably benign |
0.03 |
|
R0058:Dip2b
|
UTSW |
15 |
100,215,240 (GRCm38) |
missense |
probably benign |
0.03 |
|
R0092:Dip2b
|
UTSW |
15 |
100,202,265 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0201:Dip2b
|
UTSW |
15 |
100,186,147 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0359:Dip2b
|
UTSW |
15 |
100,211,993 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0390:Dip2b
|
UTSW |
15 |
100,193,913 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0564:Dip2b
|
UTSW |
15 |
100,162,719 (GRCm38) |
nonsense |
probably null |
|
|
R0730:Dip2b
|
UTSW |
15 |
100,171,651 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1144:Dip2b
|
UTSW |
15 |
100,154,250 (GRCm38) |
missense |
probably benign |
0.11 |
|
R1200:Dip2b
|
UTSW |
15 |
100,209,745 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1506:Dip2b
|
UTSW |
15 |
100,183,113 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1750:Dip2b
|
UTSW |
15 |
100,178,466 (GRCm38) |
missense |
probably benign |
|
|
R1760:Dip2b
|
UTSW |
15 |
100,212,029 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1773:Dip2b
|
UTSW |
15 |
100,193,961 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1812:Dip2b
|
UTSW |
15 |
100,198,938 (GRCm38) |
splice site |
probably null |
|
|
R2264:Dip2b
|
UTSW |
15 |
100,203,216 (GRCm38) |
missense |
probably benign |
0.05 |
|
R3105:Dip2b
|
UTSW |
15 |
100,142,137 (GRCm38) |
nonsense |
probably null |
|
|
R4029:Dip2b
|
UTSW |
15 |
100,186,172 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4030:Dip2b
|
UTSW |
15 |
100,186,172 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4296:Dip2b
|
UTSW |
15 |
100,181,336 (GRCm38) |
missense |
probably benign |
|
|
R4392:Dip2b
|
UTSW |
15 |
100,162,036 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4480:Dip2b
|
UTSW |
15 |
100,186,301 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4564:Dip2b
|
UTSW |
15 |
100,157,258 (GRCm38) |
nonsense |
probably null |
|
|
R4605:Dip2b
|
UTSW |
15 |
100,209,636 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4606:Dip2b
|
UTSW |
15 |
100,215,329 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R4634:Dip2b
|
UTSW |
15 |
100,160,491 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4667:Dip2b
|
UTSW |
15 |
100,151,360 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4826:Dip2b
|
UTSW |
15 |
100,169,281 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4870:Dip2b
|
UTSW |
15 |
100,195,784 (GRCm38) |
splice site |
probably null |
|
|
R4877:Dip2b
|
UTSW |
15 |
100,160,529 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
R4932:Dip2b
|
UTSW |
15 |
100,171,722 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5009:Dip2b
|
UTSW |
15 |
100,195,784 (GRCm38) |
splice site |
probably null |
|
|
R5169:Dip2b
|
UTSW |
15 |
100,205,113 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5216:Dip2b
|
UTSW |
15 |
100,211,986 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5218:Dip2b
|
UTSW |
15 |
100,154,296 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5274:Dip2b
|
UTSW |
15 |
100,212,104 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R5370:Dip2b
|
UTSW |
15 |
100,211,986 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5420:Dip2b
|
UTSW |
15 |
100,205,173 (GRCm38) |
intron |
probably benign |
|
|
R5447:Dip2b
|
UTSW |
15 |
100,211,986 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5670:Dip2b
|
UTSW |
15 |
100,190,104 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R5768:Dip2b
|
UTSW |
15 |
100,157,945 (GRCm38) |
missense |
probably benign |
0.32 |
|
R5908:Dip2b
|
UTSW |
15 |
100,151,184 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R5957:Dip2b
|
UTSW |
15 |
100,209,694 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5987:Dip2b
|
UTSW |
15 |
100,190,079 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6260:Dip2b
|
UTSW |
15 |
100,162,702 (GRCm38) |
missense |
probably benign |
0.05 |
|
R6325:Dip2b
|
UTSW |
15 |
100,154,282 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6367:Dip2b
|
UTSW |
15 |
100,115,914 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
R6391:Dip2b
|
UTSW |
15 |
100,151,276 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6422:Dip2b
|
UTSW |
15 |
100,199,011 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6818:Dip2b
|
UTSW |
15 |
100,193,954 (GRCm38) |
missense |
probably benign |
0.09 |
|
R6922:Dip2b
|
UTSW |
15 |
100,193,843 (GRCm38) |
missense |
probably benign |
0.25 |
|
R7002:Dip2b
|
UTSW |
15 |
100,160,465 (GRCm38) |
missense |
probably benign |
0.43 |
|
R7076:Dip2b
|
UTSW |
15 |
100,157,972 (GRCm38) |
splice site |
probably null |
|
|
R7176:Dip2b
|
UTSW |
15 |
100,169,318 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7255:Dip2b
|
UTSW |
15 |
100,209,627 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7463:Dip2b
|
UTSW |
15 |
100,154,157 (GRCm38) |
missense |
probably benign |
|
|
R7513:Dip2b
|
UTSW |
15 |
100,207,748 (GRCm38) |
splice site |
probably null |
|
|
R7876:Dip2b
|
UTSW |
15 |
100,191,041 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8368:Dip2b
|
UTSW |
15 |
100,154,243 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9289:Dip2b
|
UTSW |
15 |
100,173,271 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9405:Dip2b
|
UTSW |
15 |
100,195,876 (GRCm38) |
missense |
probably benign |
0.05 |
|
R9477:Dip2b
|
UTSW |
15 |
100,038,903 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9485:Dip2b
|
UTSW |
15 |
100,155,043 (GRCm38) |
missense |
probably benign |
0.05 |
|
R9533:Dip2b
|
UTSW |
15 |
100,175,297 (GRCm38) |
missense |
probably benign |
0.06 |
|
R9581:Dip2b
|
UTSW |
15 |
100,181,374 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9666:Dip2b
|
UTSW |
15 |
100,209,580 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0064:Dip2b
|
UTSW |
15 |
100,115,850 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGGACCCTTTGAGTGATGGC -3'
(R):5'- AAATCCAGGATTCCCAATAGAGG -3'
Sequencing Primer
(F):5'- CCCTTTGAGTGATGGCTGCTTC -3'
(R):5'- GGAATGCAGTGGAGTCCAGTTC -3'
|
| Posted On |
2015-11-11 |
Incidental Mutation