Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02800:Ankrd22'

360166

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ankrd22

Ensembl Gene

ENSMUSG00000024774

Gene Name

ankyrin repeat domain 22

Synonyms

D19Ertd675e, 5430429D21Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.062) question?

Stock #

IGL02800

Quality Score

Status

Chromosome

Chromosomal Location

34099949-34143441 bp(-) (GRCm39)

Type of Mutation

utr 5 prime

DNA Base Change (assembly)

T to C at 34143181 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000025686 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000025686]

AlphaFold

Q9D3J5

Predicted Effect

probably benign
Transcript: ENSMUST00000025686

SMART Domains

Protein: ENSMUSP00000025686
Gene: ENSMUSG00000024774

Domain	Start	End	E-Value	Type
ANK	39	68	1.1e-6	SMART
ANK	72	130	2.05e2	SMART
ANK	134	163	1.68e-2	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000159887

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 41 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgrg6	A	G	10: 14,296,349 (GRCm39)	I1045T	probably damaging	Het
Bahcc1	A	G	11: 120,163,760 (GRCm39)	D686G	probably damaging	Het
Carns1	A	G	19: 4,216,569 (GRCm39)		probably benign	Het
Cc2d1b	C	T	4: 108,483,333 (GRCm39)	L306F	probably benign	Het
Ccdc153	A	G	9: 44,157,129 (GRCm39)	E135G	probably damaging	Het
Ccne1	T	C	7: 37,802,224 (GRCm39)	D148G	probably damaging	Het
Cfap57	A	T	4: 118,471,947 (GRCm39)	M144K	probably damaging	Het
Chd6	A	G	2: 160,826,552 (GRCm39)	V1049A	probably damaging	Het
Cpne9	A	G	6: 113,279,034 (GRCm39)	D476G	probably benign	Het
Dna2	T	C	10: 62,797,504 (GRCm39)		probably null	Het
Eif4h	T	C	5: 134,656,459 (GRCm39)	D77G	probably benign	Het
Fhl2	C	T	1: 43,167,562 (GRCm39)	R177Q	probably benign	Het
Fxyd5	C	T	7: 30,732,404 (GRCm39)	R176H	possibly damaging	Het
G6pd2	A	G	5: 61,966,735 (GRCm39)	E170G	probably damaging	Het
Haus3	A	G	5: 34,323,668 (GRCm39)	I314T	possibly damaging	Het
Igkv4-54	A	G	6: 69,608,862 (GRCm39)	V41A	probably damaging	Het
Kidins220	T	A	12: 25,053,092 (GRCm39)	C461S	probably damaging	Het
Lsr	T	C	7: 30,657,838 (GRCm39)	D442G	probably damaging	Het
Mecom	T	C	3: 30,015,183 (GRCm39)	I847V	probably damaging	Het
Mia2	C	T	12: 59,235,277 (GRCm39)	R1326*	probably null	Het
Myo15a	C	A	11: 60,393,195 (GRCm39)	H2240N	probably damaging	Het
Or1e17	A	G	11: 73,831,942 (GRCm39)	Y290C	probably damaging	Het
Or4f62	A	T	2: 111,986,589 (GRCm39)	I98F	possibly damaging	Het
Osgep	T	A	14: 51,153,314 (GRCm39)		probably benign	Het
Pcnt	G	A	10: 76,248,417 (GRCm39)	Q901*	probably null	Het
Pgm3	T	C	9: 86,437,431 (GRCm39)	E481G	possibly damaging	Het
Plch1	T	A	3: 63,605,899 (GRCm39)	D1326V	probably benign	Het
Rabgap1l	T	C	1: 160,299,623 (GRCm39)	D590G	possibly damaging	Het
Rapsn	A	G	2: 90,873,584 (GRCm39)	M244V	probably benign	Het
Rcbtb2	T	A	14: 73,405,543 (GRCm39)	Y299*	probably null	Het
Slc8a1	A	T	17: 81,715,752 (GRCm39)	D760E	probably benign	Het
Smim23	C	A	11: 32,774,424 (GRCm39)		probably null	Het
Sva	A	G	6: 42,017,069 (GRCm39)	T59A	unknown	Het
Tacc2	T	A	7: 130,225,809 (GRCm39)	D831E	probably benign	Het
Tasor2	T	C	13: 3,635,154 (GRCm39)	N551S	probably benign	Het
Tg	G	T	15: 66,629,735 (GRCm39)	W472L	probably damaging	Het
Tmem231	A	G	8: 112,640,664 (GRCm39)	V283A	probably benign	Het
Traf4	A	T	11: 78,051,061 (GRCm39)	I365N	possibly damaging	Het
Usf3	G	A	16: 44,039,459 (GRCm39)	S1313N	probably benign	Het
Vangl1	G	A	3: 102,070,611 (GRCm39)		probably benign	Het
Wdr70	T	C	15: 8,111,980 (GRCm39)	S88G	probably benign	Het

Other mutations in Ankrd22

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01153:Ankrd22	APN	19	34,106,229 (GRCm39)	missense	probably damaging	1.00
IGL03167:Ankrd22	APN	19	34,143,174 (GRCm39)	start codon destroyed	probably null	0.77
R1993:Ankrd22	UTSW	19	34,143,174 (GRCm39)	start codon destroyed	probably null	0.77
R4659:Ankrd22	UTSW	19	34,102,968 (GRCm39)	missense	probably damaging	0.98
R4906:Ankrd22	UTSW	19	34,126,752 (GRCm39)	missense	possibly damaging	0.91
R6216:Ankrd22	UTSW	19	34,101,569 (GRCm39)	splice site	probably null
R6881:Ankrd22	UTSW	19	34,126,782 (GRCm39)	missense	probably damaging	1.00
R7468:Ankrd22	UTSW	19	34,126,692 (GRCm39)	missense	possibly damaging	0.95
R7526:Ankrd22	UTSW	19	34,126,765 (GRCm39)	missense	possibly damaging	0.93
R9082:Ankrd22	UTSW	19	34,126,662 (GRCm39)	missense	probably damaging	0.99
Z1177:Ankrd22	UTSW	19	34,100,891 (GRCm39)	frame shift	probably null

Posted On

2015-12-18