Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02803:Sult2a8'

360326

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Sult2a8

Ensembl Gene

ENSMUSG00000030378

Gene Name

sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8

Synonyms

2810007J24Rik, mL-STL

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.056) question?

Stock #

IGL02803

Quality Score

Status

Chromosome

Chromosomal Location

14144611-14180694 bp(-) (GRCm39)

Type of Mutation

utr 3 prime

DNA Base Change (assembly)

G to A at 14145630 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000147301 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000063509] [ENSMUST00000125941] [ENSMUST00000168252] [ENSMUST00000209425]

AlphaFold

Q8BGL3

Predicted Effect

probably benign
Transcript: ENSMUST00000063509

SMART Domains

Protein: ENSMUSP00000066897
Gene: ENSMUSG00000030378

Domain	Start	End	E-Value	Type
Pfam:Sulfotransfer_1	34	275	1.6e-73	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000125941

SMART Domains

Protein: ENSMUSP00000116469
Gene: ENSMUSG00000030378

Domain	Start	End	E-Value	Type
Pfam:Sulfotransfer_1	34	189	4e-47	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000168252

SMART Domains

Protein: ENSMUSP00000128428
Gene: ENSMUSG00000030378

Domain	Start	End	E-Value	Type
Pfam:Sulfotransfer_1	34	275	1.6e-73	PFAM
Pfam:Sulfotransfer_3	36	205	6.3e-10	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000209425

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 47 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Agmo	C	T	12: 37,302,480 (GRCm39)	L106F	probably benign	Het
Appl1	A	G	14: 26,673,473 (GRCm39)	I208T	possibly damaging	Het
Arap2	G	T	5: 62,906,452 (GRCm39)	A189D	probably benign	Het
Arhgef12	T	C	9: 42,883,324 (GRCm39)	K1402E	possibly damaging	Het
C7	A	C	15: 5,079,042 (GRCm39)	F89V	probably damaging	Het
Camsap2	G	A	1: 136,208,861 (GRCm39)	T877I	probably damaging	Het
Cpt2	T	C	4: 107,764,583 (GRCm39)	T394A	probably benign	Het
Csnk2a1	G	T	2: 152,116,005 (GRCm39)		probably benign	Het
Dnah10	C	A	5: 124,875,078 (GRCm39)	T2528N	probably damaging	Het
Entpd8	G	T	2: 24,975,151 (GRCm39)	W494L	probably damaging	Het
Fam114a1	T	A	5: 65,163,135 (GRCm39)		probably benign	Het
Fat4	T	C	3: 38,943,444 (GRCm39)	V779A	probably damaging	Het
Gckr	T	C	5: 31,455,548 (GRCm39)	S34P	probably damaging	Het
Golga4	T	C	9: 118,364,528 (GRCm39)	V297A	probably benign	Het
Gpr65	T	C	12: 98,241,469 (GRCm39)	S41P	probably damaging	Het
Gps1	G	T	11: 120,677,649 (GRCm39)	A221S	probably damaging	Het
Heatr1	T	A	13: 12,448,867 (GRCm39)	S1861T	probably damaging	Het
Hmces	A	G	6: 87,902,711 (GRCm39)	E184G	probably damaging	Het
Itfg1	T	C	8: 86,452,140 (GRCm39)		probably null	Het
Mrtfb	C	T	16: 13,221,020 (GRCm39)	T743I	possibly damaging	Het
Nfe2l3	A	G	6: 51,434,291 (GRCm39)	S284G	possibly damaging	Het
Nlrp2	C	A	7: 5,331,317 (GRCm39)	A360S	probably damaging	Het
Nop9	A	G	14: 55,987,533 (GRCm39)	H298R	probably benign	Het
Or5an1	A	T	19: 12,261,347 (GRCm39)	S312C	possibly damaging	Het
Or5h17	T	A	16: 58,820,321 (GRCm39)	V91E	probably benign	Het
Or6ae1	T	C	7: 139,742,287 (GRCm39)	D192G	possibly damaging	Het
Osgin1	A	G	8: 120,170,006 (GRCm39)	M158V	probably benign	Het
Patj	C	A	4: 98,314,301 (GRCm39)	Q374K	probably damaging	Het
Pck1	G	T	2: 172,997,797 (GRCm39)	G289W	probably damaging	Het
Phkg1	T	G	5: 129,894,895 (GRCm39)	I219L	possibly damaging	Het
Ppp1r15b	G	A	1: 133,061,081 (GRCm39)	A533T	probably damaging	Het
Ppwd1	T	C	13: 104,350,192 (GRCm39)	I398V	probably benign	Het
Prkdc	A	G	16: 15,651,530 (GRCm39)		probably benign	Het
Psg25	G	A	7: 18,260,212 (GRCm39)	L229F	possibly damaging	Het
Rps6ka1	T	A	4: 133,608,265 (GRCm39)	Q24L	probably benign	Het
Sgk3	T	C	1: 9,949,273 (GRCm39)	I147T	possibly damaging	Het
Slc25a24	T	A	3: 109,062,387 (GRCm39)	I159N	probably damaging	Het
Slc26a4	T	C	12: 31,572,526 (GRCm39)		probably null	Het
Slc35f4	T	C	14: 49,541,714 (GRCm39)	I347V	probably benign	Het
Spag17	A	T	3: 100,016,713 (GRCm39)	M2163L	probably benign	Het
Stab2	C	T	10: 86,786,133 (GRCm39)		probably benign	Het
Syne2	T	C	12: 76,078,320 (GRCm39)	L4718P	probably damaging	Het
Timd4	G	T	11: 46,706,521 (GRCm39)	G108W	probably damaging	Het
Timm9	T	C	12: 71,173,148 (GRCm39)		probably benign	Het
Vmn2r98	G	A	17: 19,286,275 (GRCm39)	V258I	probably benign	Het
Zcchc9	C	T	13: 91,949,000 (GRCm39)	V174I	probably benign	Het
Zdbf2	T	C	1: 63,342,236 (GRCm39)	V205A	possibly damaging	Het

Other mutations in Sult2a8

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01558:Sult2a8	APN	7	14,159,377 (GRCm39)	nonsense	probably null
IGL01904:Sult2a8	APN	7	14,159,382 (GRCm39)	missense	probably damaging	1.00
IGL02060:Sult2a8	APN	7	14,159,326 (GRCm39)	missense	probably damaging	1.00
IGL02532:Sult2a8	APN	7	14,150,183 (GRCm39)	missense	probably benign	0.01
IGL02663:Sult2a8	APN	7	14,159,368 (GRCm39)	missense	possibly damaging	0.52
R1070:Sult2a8	UTSW	7	14,147,698 (GRCm39)	missense	probably damaging	0.99
R1251:Sult2a8	UTSW	7	14,159,350 (GRCm39)	nonsense	probably null
R1465:Sult2a8	UTSW	7	14,150,208 (GRCm39)	missense	probably benign	0.00
R1465:Sult2a8	UTSW	7	14,150,208 (GRCm39)	missense	probably benign	0.00
R1799:Sult2a8	UTSW	7	14,157,451 (GRCm39)	missense	probably damaging	1.00
R2196:Sult2a8	UTSW	7	14,161,778 (GRCm39)	missense	probably benign	0.00
R4233:Sult2a8	UTSW	7	14,147,608 (GRCm39)	missense	probably benign	0.01
R4713:Sult2a8	UTSW	7	14,159,402 (GRCm39)	missense	probably benign	0.02
R4964:Sult2a8	UTSW	7	14,159,457 (GRCm39)	missense	probably damaging	0.98
R5114:Sult2a8	UTSW	7	14,147,584 (GRCm39)	missense	probably benign	0.01
R5330:Sult2a8	UTSW	7	14,147,679 (GRCm39)	missense	possibly damaging	0.53
R5439:Sult2a8	UTSW	7	14,159,439 (GRCm39)	missense	probably damaging	1.00
R5662:Sult2a8	UTSW	7	14,161,765 (GRCm39)	missense	probably benign	0.13
R7353:Sult2a8	UTSW	7	14,147,640 (GRCm39)	missense	possibly damaging	0.95
R7366:Sult2a8	UTSW	7	14,150,254 (GRCm39)	splice site	probably null
R7832:Sult2a8	UTSW	7	14,147,596 (GRCm39)	missense	probably benign	0.02
R9499:Sult2a8	UTSW	7	14,157,487 (GRCm39)	missense	probably damaging	1.00

Posted On

2015-12-18