Incidental Mutation 'IGL02808:Pramel16'
ID 360502
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Pramel16
Ensembl Gene ENSMUSG00000078511
Gene Name PRAME like 16
Synonyms Pramef25, Gm13109
Accession Numbers
Essential gene? Probably non essential (E-score: 0.052) question?
Stock # IGL02808
Quality Score
Status
Chromosome 4
Chromosomal Location 143675150-143677586 bp(-) (GRCm39)
Type of Mutation utr 5 prime
DNA Base Change (assembly) T to A at 143677585 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000101392 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000105766]
AlphaFold A2ASI9
Predicted Effect probably benign
Transcript: ENSMUST00000105766
SMART Domains Protein: ENSMUSP00000101392
Gene: ENSMUSG00000078511

DomainStartEndE-ValueType
SCOP:d1a4ya_ 223 427 2e-10 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 30 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adk C T 14: 21,153,901 (GRCm39) P35S probably benign Het
Ankmy1 T A 1: 92,814,388 (GRCm39) D373V probably damaging Het
Aox3 A G 1: 58,181,859 (GRCm39) Y282C probably damaging Het
Bcas3 A G 11: 85,386,677 (GRCm39) T371A probably benign Het
Bckdhb T C 9: 83,870,898 (GRCm39) V136A probably benign Het
Ccdc18 G T 5: 108,283,835 (GRCm39) probably benign Het
Cdc25a T A 9: 109,712,667 (GRCm39) probably null Het
Ckap5 T A 2: 91,426,859 (GRCm39) Y1394N probably damaging Het
Dhx15 A G 5: 52,319,041 (GRCm39) V458A possibly damaging Het
Dram1 T C 10: 88,172,786 (GRCm39) Y136C probably damaging Het
Dusp19 A G 2: 80,447,815 (GRCm39) K30E probably benign Het
Elmo2 T C 2: 165,133,627 (GRCm39) probably benign Het
Fcho1 G A 8: 72,165,185 (GRCm39) S424L possibly damaging Het
Ganc A G 2: 120,241,992 (GRCm39) T57A probably benign Het
Hgs T A 11: 120,360,492 (GRCm39) Y63* probably null Het
Marchf6 A T 15: 31,478,552 (GRCm39) N594K probably benign Het
Muc5ac C A 7: 141,359,512 (GRCm39) T1323N possibly damaging Het
Mycn T C 12: 12,989,893 (GRCm39) S168G probably benign Het
Phf11d G T 14: 59,586,739 (GRCm39) Q298K probably damaging Het
Pkd1 T A 17: 24,812,478 (GRCm39) Y3804N probably damaging Het
Prr14l A G 5: 32,985,526 (GRCm39) I1323T possibly damaging Het
Pyroxd2 T C 19: 42,719,781 (GRCm39) E475G probably benign Het
Ros1 T C 10: 52,001,985 (GRCm39) K1046E probably damaging Het
Sema7a C T 9: 57,867,631 (GRCm39) A461V probably benign Het
Slc30a2 T A 4: 134,071,360 (GRCm39) I31N possibly damaging Het
Srebf1 C A 11: 60,092,539 (GRCm39) probably null Het
Srms A T 2: 180,849,501 (GRCm39) I301N probably damaging Het
Tmem130 A G 5: 144,680,433 (GRCm39) Y324H probably damaging Het
Ttn G A 2: 76,601,602 (GRCm39) T18654I probably benign Het
Vmn2r6 T A 3: 64,463,917 (GRCm39) T306S probably damaging Het
Other mutations in Pramel16
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01012:Pramel16 APN 4 143,676,784 (GRCm39) splice site probably benign
IGL01562:Pramel16 APN 4 143,677,435 (GRCm39) missense probably damaging 1.00
IGL02422:Pramel16 APN 4 143,676,453 (GRCm39) missense probably benign 0.25
IGL02632:Pramel16 APN 4 143,676,507 (GRCm39) missense possibly damaging 0.84
IGL02745:Pramel16 APN 4 143,677,294 (GRCm39) missense probably damaging 1.00
IGL02883:Pramel16 APN 4 143,676,418 (GRCm39) missense possibly damaging 0.64
IGL02961:Pramel16 APN 4 143,675,717 (GRCm39) missense probably damaging 1.00
IGL03092:Pramel16 APN 4 143,676,767 (GRCm39) missense probably damaging 0.97
FR4340:Pramel16 UTSW 4 143,676,312 (GRCm39) missense probably damaging 0.99
FR4342:Pramel16 UTSW 4 143,676,327 (GRCm39) frame shift probably null
FR4342:Pramel16 UTSW 4 143,676,312 (GRCm39) missense probably damaging 0.99
R0533:Pramel16 UTSW 4 143,677,290 (GRCm39) missense possibly damaging 0.85
R0606:Pramel16 UTSW 4 143,676,453 (GRCm39) missense probably benign 0.25
R1624:Pramel16 UTSW 4 143,676,400 (GRCm39) missense possibly damaging 0.47
R1898:Pramel16 UTSW 4 143,677,298 (GRCm39) missense probably damaging 1.00
R2029:Pramel16 UTSW 4 143,676,453 (GRCm39) missense probably benign 0.25
R2867:Pramel16 UTSW 4 143,675,456 (GRCm39) missense probably benign 0.00
R2867:Pramel16 UTSW 4 143,675,456 (GRCm39) missense probably benign 0.00
R2894:Pramel16 UTSW 4 143,675,692 (GRCm39) missense probably damaging 1.00
R4111:Pramel16 UTSW 4 143,676,475 (GRCm39) missense possibly damaging 0.93
R4298:Pramel16 UTSW 4 143,675,713 (GRCm39) nonsense probably null
R4360:Pramel16 UTSW 4 143,677,433 (GRCm39) missense possibly damaging 0.81
R4361:Pramel16 UTSW 4 143,677,433 (GRCm39) missense possibly damaging 0.81
R5137:Pramel16 UTSW 4 143,675,690 (GRCm39) missense probably benign 0.08
R5195:Pramel16 UTSW 4 143,677,450 (GRCm39) missense probably damaging 0.99
R5312:Pramel16 UTSW 4 143,675,665 (GRCm39) missense possibly damaging 0.96
R5548:Pramel16 UTSW 4 143,676,550 (GRCm39) missense probably benign 0.24
R5591:Pramel16 UTSW 4 143,675,377 (GRCm39) missense probably damaging 1.00
R5644:Pramel16 UTSW 4 143,675,374 (GRCm39) missense probably benign 0.01
R6018:Pramel16 UTSW 4 143,677,469 (GRCm39) missense possibly damaging 0.61
R6177:Pramel16 UTSW 4 143,675,576 (GRCm39) missense possibly damaging 0.51
R6335:Pramel16 UTSW 4 143,675,602 (GRCm39) missense probably benign 0.02
R6376:Pramel16 UTSW 4 143,677,267 (GRCm39) missense probably benign 0.03
R6572:Pramel16 UTSW 4 143,676,262 (GRCm39) missense probably benign 0.01
R6845:Pramel16 UTSW 4 143,676,394 (GRCm39) missense probably benign
R6939:Pramel16 UTSW 4 143,675,366 (GRCm39) missense probably benign 0.09
R7081:Pramel16 UTSW 4 143,675,848 (GRCm39) missense probably damaging 1.00
R7505:Pramel16 UTSW 4 143,676,273 (GRCm39) missense possibly damaging 0.94
R7711:Pramel16 UTSW 4 143,675,822 (GRCm39) missense probably benign 0.22
R8284:Pramel16 UTSW 4 143,676,695 (GRCm39) missense possibly damaging 0.95
R8297:Pramel16 UTSW 4 143,675,690 (GRCm39) missense probably benign 0.08
R8299:Pramel16 UTSW 4 143,677,327 (GRCm39) missense probably benign 0.24
R8700:Pramel16 UTSW 4 143,675,701 (GRCm39) missense possibly damaging 0.51
R9179:Pramel16 UTSW 4 143,676,294 (GRCm39) missense probably benign 0.01
R9199:Pramel16 UTSW 4 143,675,656 (GRCm39) missense probably damaging 1.00
R9214:Pramel16 UTSW 4 143,675,750 (GRCm39) missense probably benign 0.00
R9411:Pramel16 UTSW 4 143,676,215 (GRCm39) missense probably damaging 1.00
RF011:Pramel16 UTSW 4 143,675,478 (GRCm39) missense probably damaging 0.96
RF013:Pramel16 UTSW 4 143,675,478 (GRCm39) missense probably damaging 0.96
RF021:Pramel16 UTSW 4 143,675,478 (GRCm39) missense probably damaging 0.96
Z1176:Pramel16 UTSW 4 143,676,693 (GRCm39) missense probably benign 0.13
Posted On 2015-12-18