Incidental Mutation 'IGL02809:Fpr-rs3'
| ID |
360519 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Fpr-rs3
|
| Ensembl Gene |
ENSMUSG00000060701 |
| Gene Name |
formyl peptide receptor, related sequence 3 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.127)
|
| Stock # |
IGL02809
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
17 |
| Chromosomal Location |
20844108-20845139 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 20844225 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Serine
at position 305
(R305S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071179
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071189]
|
| AlphaFold |
O88537 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000071189
AA Change: R305S
PolyPhen 2
Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000071179
Gene: ENSMUSG00000060701
AA Change: R305S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:7tm_1
|
43 |
297 |
1.8e-36 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 23 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Camkmt |
A |
T |
17: 85,702,076 (GRCm39) |
N180I |
probably damaging |
Het |
| Card9 |
A |
G |
2: 26,246,876 (GRCm39) |
M324T |
probably benign |
Het |
| Cenpf |
T |
C |
1: 189,414,555 (GRCm39) |
|
probably benign |
Het |
| Cerkl |
A |
G |
2: 79,172,546 (GRCm39) |
S349P |
possibly damaging |
Het |
| Ctsj |
C |
T |
13: 61,150,974 (GRCm39) |
S162N |
probably damaging |
Het |
| Fancm |
A |
G |
12: 65,168,441 (GRCm39) |
I1601M |
possibly damaging |
Het |
| Gpatch8 |
A |
G |
11: 102,378,416 (GRCm39) |
V178A |
unknown |
Het |
| Itga4 |
A |
G |
2: 79,110,921 (GRCm39) |
Y253C |
probably damaging |
Het |
| Kntc1 |
T |
C |
5: 123,914,645 (GRCm39) |
F655S |
probably damaging |
Het |
| Manba |
A |
G |
3: 135,253,321 (GRCm39) |
D414G |
probably damaging |
Het |
| Nfkbid |
C |
T |
7: 30,124,660 (GRCm39) |
T7I |
possibly damaging |
Het |
| Ngly1 |
G |
T |
14: 16,281,791 (GRCm38) |
C349F |
probably damaging |
Het |
| Palld |
T |
C |
8: 61,968,281 (GRCm39) |
N1095S |
probably damaging |
Het |
| Sp100 |
C |
T |
1: 85,608,845 (GRCm39) |
R325W |
probably damaging |
Het |
| Stxbp4 |
A |
G |
11: 90,491,010 (GRCm39) |
|
probably null |
Het |
| Tle2 |
C |
A |
10: 81,422,196 (GRCm39) |
|
probably null |
Het |
| Tlr13 |
G |
T |
X: 105,200,297 (GRCm39) |
|
probably benign |
Het |
| Ttc32 |
G |
A |
12: 9,085,879 (GRCm39) |
R142Q |
possibly damaging |
Het |
| Ubap2l |
G |
A |
3: 89,928,553 (GRCm39) |
T526M |
probably damaging |
Het |
| Uggt2 |
T |
C |
14: 119,328,150 (GRCm39) |
E124G |
probably benign |
Het |
| Vmn1r72 |
A |
G |
7: 11,403,930 (GRCm39) |
F173L |
probably benign |
Het |
| Xab2 |
T |
C |
8: 3,660,175 (GRCm39) |
S851G |
probably benign |
Het |
| Zfp808 |
A |
G |
13: 62,320,994 (GRCm39) |
K741R |
probably benign |
Het |
|
| Other mutations in Fpr-rs3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01561:Fpr-rs3
|
APN |
17 |
20,844,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02230:Fpr-rs3
|
APN |
17 |
20,844,190 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02503:Fpr-rs3
|
APN |
17 |
20,844,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03212:Fpr-rs3
|
APN |
17 |
20,844,121 (GRCm39) |
missense |
probably benign |
0.00 |
|
I2288:Fpr-rs3
|
UTSW |
17 |
20,844,757 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0318:Fpr-rs3
|
UTSW |
17 |
20,844,410 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0565:Fpr-rs3
|
UTSW |
17 |
20,844,283 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1005:Fpr-rs3
|
UTSW |
17 |
20,844,346 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1986:Fpr-rs3
|
UTSW |
17 |
20,844,103 (GRCm39) |
splice site |
probably null |
|
|
R3941:Fpr-rs3
|
UTSW |
17 |
20,845,111 (GRCm39) |
missense |
probably benign |
0.42 |
|
R4297:Fpr-rs3
|
UTSW |
17 |
20,845,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4809:Fpr-rs3
|
UTSW |
17 |
20,844,683 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4959:Fpr-rs3
|
UTSW |
17 |
20,844,211 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4973:Fpr-rs3
|
UTSW |
17 |
20,844,211 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5116:Fpr-rs3
|
UTSW |
17 |
20,844,562 (GRCm39) |
missense |
probably benign |
0.12 |
|
R5356:Fpr-rs3
|
UTSW |
17 |
20,844,596 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5394:Fpr-rs3
|
UTSW |
17 |
20,844,470 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5779:Fpr-rs3
|
UTSW |
17 |
20,844,488 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6091:Fpr-rs3
|
UTSW |
17 |
20,844,532 (GRCm39) |
missense |
probably benign |
0.30 |
|
R6389:Fpr-rs3
|
UTSW |
17 |
20,844,230 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6860:Fpr-rs3
|
UTSW |
17 |
20,844,560 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7578:Fpr-rs3
|
UTSW |
17 |
20,844,293 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8153:Fpr-rs3
|
UTSW |
17 |
20,844,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8711:Fpr-rs3
|
UTSW |
17 |
20,844,554 (GRCm39) |
missense |
probably benign |
|
|
R8768:Fpr-rs3
|
UTSW |
17 |
20,844,944 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0018:Fpr-rs3
|
UTSW |
17 |
20,844,899 (GRCm39) |
missense |
probably benign |
0.30 |
|
| Posted On |
2015-12-18 |
Incidental Mutation