Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02820:Xkr9'

360948

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Xkr9

Ensembl Gene

ENSMUSG00000067813

Gene Name

X-linked Kx blood group related 9

Synonyms

LOC381246

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.060) question?

Stock #

IGL02820

Quality Score

Status

Chromosome

Chromosomal Location

13738995-13771947 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 13771173 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Isoleucine at position 230 (V230I)

Ref Sequence

ENSEMBL: ENSMUSP00000085900 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000088542]

AlphaFold

Q5GH62

Predicted Effect

probably benign
Transcript: ENSMUST00000088542
AA Change: V230I

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000085900
Gene: ENSMUSG00000067813
AA Change: V230I

Domain	Start	End	E-Value	Type
Pfam:XK-related	9	346	2.8e-87	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 49 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
9030624G23Rik	T	C	12: 24,124,417 (GRCm39)	Y86C	probably benign	Het
Adgra2	G	A	8: 27,607,535 (GRCm39)	V47M	probably damaging	Het
Anks1b	T	C	10: 89,912,921 (GRCm39)	C349R	possibly damaging	Het
Anks4b	A	T	7: 119,781,914 (GRCm39)		probably benign	Het
Apobec2	A	G	17: 48,730,295 (GRCm39)	S124P	probably damaging	Het
Brd8	G	A	18: 34,740,354 (GRCm39)	S493L	probably benign	Het
Cbln3	A	G	14: 56,120,944 (GRCm39)	Y126H	probably damaging	Het
Ccdc138	T	C	10: 58,364,721 (GRCm39)		probably benign	Het
Cckbr	C	T	7: 105,083,238 (GRCm39)	A147V	probably damaging	Het
Ceacam2	T	A	7: 25,219,411 (GRCm39)	H283L	probably damaging	Het
Cfap251	A	G	5: 123,392,699 (GRCm39)		probably benign	Het
Clasp1	A	G	1: 118,478,834 (GRCm39)	D718G	possibly damaging	Het
Clmn	A	T	12: 104,739,493 (GRCm39)	Y979N	probably damaging	Het
Ddias	T	C	7: 92,508,551 (GRCm39)	T455A	probably benign	Het
Dennd5b	T	C	6: 148,920,840 (GRCm39)	R851G	probably null	Het
Dock1	T	C	7: 134,768,944 (GRCm39)	V1771A	probably benign	Het
Dysf	T	A	6: 84,077,187 (GRCm39)	L694Q	probably damaging	Het
Faim2	T	C	15: 99,419,138 (GRCm39)	Y77C	probably benign	Het
Fbxw22	A	T	9: 109,215,732 (GRCm39)	I172N	probably damaging	Het
Fhad1	C	T	4: 141,646,069 (GRCm39)	D298N	probably benign	Het
Fyb1	T	G	15: 6,688,040 (GRCm39)	V800G	possibly damaging	Het
Gcm1	T	C	9: 77,971,844 (GRCm39)	F262L	probably benign	Het
Gm21983	T	C	7: 26,879,605 (GRCm39)	M121V	probably benign	Het
Gm9996	A	T	10: 29,019,657 (GRCm39)		probably benign	Het
Gstm3	A	T	3: 107,876,074 (GRCm39)		probably benign	Het
Gsto2	G	T	19: 47,863,398 (GRCm39)	E91D	probably damaging	Het
Hs6st3	G	T	14: 119,376,492 (GRCm39)	M222I	possibly damaging	Het
Ighv3-6	T	C	12: 114,251,850 (GRCm39)	D90G	probably damaging	Het
Itgb1bp1	C	T	12: 21,326,854 (GRCm39)	A40T	possibly damaging	Het
Kcns3	C	T	12: 11,141,872 (GRCm39)	E276K	probably benign	Het
Lamc3	C	T	2: 31,813,034 (GRCm39)	R1007C	probably damaging	Het
Lnx2	A	T	5: 146,978,877 (GRCm39)	M125K	probably damaging	Het
Lyst	T	A	13: 13,812,643 (GRCm39)	N1018K	probably benign	Het
Mctp2	T	A	7: 71,895,290 (GRCm39)	S186C	probably damaging	Het
Or1j20	A	T	2: 36,759,871 (GRCm39)	T98S	probably benign	Het
Polg	T	C	7: 79,109,519 (GRCm39)	T433A	possibly damaging	Het
Rdh13	C	T	7: 4,438,059 (GRCm39)	V127M	probably damaging	Het
Rdh16	A	G	10: 127,649,470 (GRCm39)	T309A	probably benign	Het
Reep5	A	T	18: 34,506,312 (GRCm39)	D21E	probably benign	Het
Rptn	A	T	3: 93,304,227 (GRCm39)	N520I	probably benign	Het
Rttn	T	C	18: 89,047,122 (GRCm39)	L928P	probably damaging	Het
Slc44a2	A	G	9: 21,254,273 (GRCm39)	I212V	probably benign	Het
Snupn	A	G	9: 56,870,332 (GRCm39)	T71A	probably benign	Het
Ssu2	T	C	6: 112,359,353 (GRCm39)	N89S	probably benign	Het
Thsd7a	A	G	6: 12,321,071 (GRCm39)	S1535P	probably damaging	Het
Tmt1a	C	A	15: 100,202,933 (GRCm39)	S51*	probably null	Het
Uba7	A	T	9: 107,858,715 (GRCm39)	S849C	probably benign	Het
Vmn2r80	A	G	10: 79,007,439 (GRCm39)	T472A	probably benign	Het
Wdr6	A	G	9: 108,455,743 (GRCm39)	I17T	probably benign	Het

Other mutations in Xkr9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01990:Xkr9	APN	1	13,771,203 (GRCm39)	missense	probably benign	0.00
IGL02090:Xkr9	APN	1	13,771,600 (GRCm39)	missense	probably damaging	1.00
IGL02405:Xkr9	APN	1	13,742,997 (GRCm39)	splice site	probably benign
IGL02523:Xkr9	APN	1	13,754,474 (GRCm39)	missense	probably benign	0.01
IGL02792:Xkr9	APN	1	13,771,027 (GRCm39)	missense	probably damaging	1.00
IGL02821:Xkr9	APN	1	13,742,799 (GRCm39)	missense	probably damaging	1.00
IGL03170:Xkr9	APN	1	13,771,036 (GRCm39)	missense	possibly damaging	0.72
IGL03222:Xkr9	APN	1	13,771,505 (GRCm39)	nonsense	probably null
R0044:Xkr9	UTSW	1	13,754,286 (GRCm39)	nonsense	probably null
R0044:Xkr9	UTSW	1	13,754,286 (GRCm39)	nonsense	probably null
R0595:Xkr9	UTSW	1	13,771,008 (GRCm39)	missense	probably benign	0.02
R1337:Xkr9	UTSW	1	13,771,348 (GRCm39)	missense	possibly damaging	0.94
R1670:Xkr9	UTSW	1	13,771,167 (GRCm39)	missense	probably damaging	0.97
R5007:Xkr9	UTSW	1	13,771,387 (GRCm39)	missense	probably damaging	0.98
R6133:Xkr9	UTSW	1	13,754,359 (GRCm39)	missense	probably benign	0.01
R6302:Xkr9	UTSW	1	13,742,726 (GRCm39)	missense	probably damaging	1.00
R8153:Xkr9	UTSW	1	13,754,363 (GRCm39)	missense	probably benign	0.10
R8440:Xkr9	UTSW	1	13,771,603 (GRCm39)	missense	probably benign	0.31
R8520:Xkr9	UTSW	1	13,771,603 (GRCm39)	missense	probably benign	0.31
R8823:Xkr9	UTSW	1	13,742,832 (GRCm39)	missense	probably benign	0.43
R8985:Xkr9	UTSW	1	13,770,990 (GRCm39)	missense	probably benign
R9084:Xkr9	UTSW	1	13,742,733 (GRCm39)	missense	probably benign	0.15
R9441:Xkr9	UTSW	1	13,771,587 (GRCm39)	missense	possibly damaging	0.94
R9658:Xkr9	UTSW	1	13,771,318 (GRCm39)	missense	probably damaging	1.00
X0025:Xkr9	UTSW	1	13,742,858 (GRCm39)	missense	probably benign	0.43

Posted On

2015-12-18