Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02820:Ccdc138'

360989

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ccdc138

Ensembl Gene

ENSMUSG00000038010

Gene Name

coiled-coil domain containing 138

Synonyms

6230424H07Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.135) question?

Stock #

IGL02820

Quality Score

Status

Chromosome

Chromosomal Location

58497948-58576244 bp(+) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

T to C at 58528899 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000043040 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000036576]

AlphaFold

Q0VF22

Predicted Effect

probably benign
Transcript: ENSMUST00000036576

SMART Domains

Protein: ENSMUSP00000043040
Gene: ENSMUSG00000038010

Domain	Start	End	E-Value	Type
coiled coil region	259	339	N/A	INTRINSIC
low complexity region	355	365	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 49 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
9030624G23Rik	T	C	12: 24,074,416	Y86C	probably benign	Het
Adgra2	G	A	8: 27,117,507	V47M	probably damaging	Het
Anks1b	T	C	10: 90,077,059	C349R	possibly damaging	Het
Anks4b	A	T	7: 120,182,691		probably benign	Het
Apobec2	A	G	17: 48,423,267	S124P	probably damaging	Het
Brd8	G	A	18: 34,607,301	S493L	probably benign	Het
Cbln3	A	G	14: 55,883,487	Y126H	probably damaging	Het
Cckbr	C	T	7: 105,434,031	A147V	probably damaging	Het
Ceacam2	T	A	7: 25,519,986	H283L	probably damaging	Het
Clasp1	A	G	1: 118,551,104	D718G	possibly damaging	Het
Clmn	A	T	12: 104,773,234	Y979N	probably damaging	Het
Ddias	T	C	7: 92,859,343	T455A	probably benign	Het
Dennd5b	T	C	6: 149,019,342	R851G	probably null	Het
Dock1	T	C	7: 135,167,215	V1771A	probably benign	Het
Dysf	T	A	6: 84,100,205	L694Q	probably damaging	Het
Faim2	T	C	15: 99,521,257	Y77C	probably benign	Het
Fbxw22	A	T	9: 109,386,664	I172N	probably damaging	Het
Fhad1	C	T	4: 141,918,758	D298N	probably benign	Het
Fyb	T	G	15: 6,658,559	V800G	possibly damaging	Het
Gcm1	T	C	9: 78,064,562	F262L	probably benign	Het
Gm21983	T	C	7: 27,180,180	M121V	probably benign	Het
Gm9996	A	T	10: 29,143,661		probably benign	Het
Gstm3	A	T	3: 107,968,758		probably benign	Het
Gsto2	G	T	19: 47,874,959	E91D	probably damaging	Het
Hs6st3	G	T	14: 119,139,080	M222I	possibly damaging	Het
Ighv3-6	T	C	12: 114,288,230	D90G	probably damaging	Het
Itgb1bp1	C	T	12: 21,276,853	A40T	possibly damaging	Het
Kcns3	C	T	12: 11,091,871	E276K	probably benign	Het
Lamc3	C	T	2: 31,923,022	R1007C	probably damaging	Het
Lnx2	A	T	5: 147,042,067	M125K	probably damaging	Het
Lyst	T	A	13: 13,638,058	N1018K	probably benign	Het
Mctp2	T	A	7: 72,245,542	S186C	probably damaging	Het
Mettl7a1	C	A	15: 100,305,052	S51*	probably null	Het
Olfr352	A	T	2: 36,869,859	T98S	probably benign	Het
Polg	T	C	7: 79,459,771	T433A	possibly damaging	Het
Rdh13	C	T	7: 4,435,060	V127M	probably damaging	Het
Rdh16	A	G	10: 127,813,601	T309A	probably benign	Het
Reep5	A	T	18: 34,373,259	D21E	probably benign	Het
Rptn	A	T	3: 93,396,920	N520I	probably benign	Het
Rttn	T	C	18: 89,028,998	L928P	probably damaging	Het
Slc44a2	A	G	9: 21,342,977	I212V	probably benign	Het
Snupn	A	G	9: 56,963,048	T71A	probably benign	Het
Ssu2	T	C	6: 112,382,392	N89S	probably benign	Het
Thsd7a	A	G	6: 12,321,072	S1535P	probably damaging	Het
Uba7	A	T	9: 107,981,516	S849C	probably benign	Het
Vmn2r80	A	G	10: 79,171,605	T472A	probably benign	Het
Wdr6	A	G	9: 108,578,544	I17T	probably benign	Het
Wdr66	A	G	5: 123,254,636		probably benign	Het
Xkr9	G	A	1: 13,700,949	V230I	probably benign	Het

Other mutations in Ccdc138

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00763:Ccdc138	APN	10	58575715	missense	probably damaging	1.00
IGL00957:Ccdc138	APN	10	58529016	splice site	probably benign
IGL01012:Ccdc138	APN	10	58540915	critical splice donor site	probably null
IGL01725:Ccdc138	APN	10	58528923	missense	possibly damaging	0.50
IGL01996:Ccdc138	APN	10	58562030	missense	probably damaging	1.00
IGL02083:Ccdc138	APN	10	58544914	splice site	probably benign
IGL02652:Ccdc138	APN	10	58513079	missense	probably benign	0.00
IGL02934:Ccdc138	APN	10	58573580	splice site	probably benign
IGL03231:Ccdc138	APN	10	58573706	missense	probably damaging	1.00
R0128:Ccdc138	UTSW	10	58528360	missense	probably damaging	1.00
R0271:Ccdc138	UTSW	10	58575823	missense	probably damaging	0.99
R0480:Ccdc138	UTSW	10	58561967	missense	probably damaging	1.00
R0560:Ccdc138	UTSW	10	58575717	missense	probably damaging	1.00
R0645:Ccdc138	UTSW	10	58575720	missense	probably damaging	1.00
R1405:Ccdc138	UTSW	10	58545117	splice site	probably benign
R2032:Ccdc138	UTSW	10	58513162	missense	possibly damaging	0.71
R2097:Ccdc138	UTSW	10	58561937	nonsense	probably null
R2350:Ccdc138	UTSW	10	58561893	splice site	probably benign
R2571:Ccdc138	UTSW	10	58513222	missense	probably benign	0.25
R3787:Ccdc138	UTSW	10	58538270	missense	probably damaging	1.00
R3805:Ccdc138	UTSW	10	58561997	missense	possibly damaging	0.95
R4582:Ccdc138	UTSW	10	58507643	critical splice donor site	probably null
R4630:Ccdc138	UTSW	10	58573655	missense	probably damaging	1.00
R4801:Ccdc138	UTSW	10	58573643	missense	probably damaging	1.00
R4802:Ccdc138	UTSW	10	58573643	missense	probably damaging	1.00
R4883:Ccdc138	UTSW	10	58561996	missense	probably benign	0.03
R4908:Ccdc138	UTSW	10	58544995	missense	possibly damaging	0.84
R5032:Ccdc138	UTSW	10	58573636	missense	probably damaging	1.00
R5155:Ccdc138	UTSW	10	58507572	missense	probably benign	0.00
R5287:Ccdc138	UTSW	10	58575705	missense	possibly damaging	0.89
R5683:Ccdc138	UTSW	10	58540819	missense	probably damaging	1.00
R5963:Ccdc138	UTSW	10	58575757	missense	possibly damaging	0.90
R6530:Ccdc138	UTSW	10	58544968	missense	probably damaging	1.00
R7148:Ccdc138	UTSW	10	58538280	missense	probably damaging	1.00
R7217:Ccdc138	UTSW	10	58509600	missense	probably benign	0.33
R9031:Ccdc138	UTSW	10	58545071	missense	probably damaging	1.00
R9080:Ccdc138	UTSW	10	58562062	missense	probably damaging	0.99
R9104:Ccdc138	UTSW	10	58513160	missense	probably benign	0.05
R9134:Ccdc138	UTSW	10	58538280	missense	probably damaging	0.99
R9300:Ccdc138	UTSW	10	58507626	missense	probably benign	0.00
R9409:Ccdc138	UTSW	10	58538313	missense	probably damaging	1.00

Posted On

2015-12-18