Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02825:Vmn2r101'

361149

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r101

Ensembl Gene

ENSMUSG00000094892

Gene Name

vomeronasal 2, receptor 101

Synonyms

EG627576

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.102) question?

Stock #

IGL02825

Quality Score

Status

Chromosome

Chromosomal Location

19797493-19832579 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 19810132 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Asparagine at position 306 (I306N)

Ref Sequence

ENSEMBL: ENSMUSP00000131583 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000171914]

AlphaFold

E9PZS9

Predicted Effect

probably benign
Transcript: ENSMUST00000171914
AA Change: I306N

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000131583
Gene: ENSMUSG00000094892
AA Change: I306N

Domain	Start	End	E-Value	Type
signal peptide	1	19	N/A	INTRINSIC
Pfam:ANF_receptor	82	466	1.6e-36	PFAM
Pfam:NCD3G	509	562	6.4e-22	PFAM
Pfam:7tm_3	595	830	1.4e-51	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 42 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abo	A	G	2: 26,733,710 (GRCm39)	V163A	possibly damaging	Het
Ap1b1	G	T	11: 4,983,738 (GRCm39)	A664S	possibly damaging	Het
B3gnt4	T	C	5: 123,649,114 (GRCm39)	F160L	possibly damaging	Het
Brd3	T	C	2: 27,339,275 (GRCm39)	E685G	probably damaging	Het
Cacna2d2	C	T	9: 107,401,659 (GRCm39)	R746C	probably damaging	Het
Ces1d	C	A	8: 93,896,346 (GRCm39)		probably null	Het
Chl1	T	A	6: 103,645,764 (GRCm39)	V268E	possibly damaging	Het
Cpb1	T	A	3: 20,303,889 (GRCm39)	I392F	probably damaging	Het
Dnai1	T	C	4: 41,625,101 (GRCm39)		probably benign	Het
Dync2h1	T	C	9: 6,955,901 (GRCm39)		probably benign	Het
Edc4	T	C	8: 106,617,243 (GRCm39)	S1021P	probably damaging	Het
Exoc7	A	C	11: 116,188,411 (GRCm39)	L296R	probably damaging	Het
Fgd5	A	G	6: 92,015,068 (GRCm39)		probably null	Het
Gm28042	T	A	2: 119,862,125 (GRCm39)	M232K	probably damaging	Het
Ints1	A	T	5: 139,750,494 (GRCm39)	S888T	probably benign	Het
Kirrel1	A	T	3: 86,996,595 (GRCm39)		probably benign	Het
Lrp1	C	T	10: 127,378,474 (GRCm39)	R4037Q	probably damaging	Het
Lrrc37	G	A	11: 103,507,894 (GRCm39)		probably benign	Het
Lrrn3	A	T	12: 41,502,592 (GRCm39)	V575D	probably damaging	Het
Mapk11	A	G	15: 89,030,585 (GRCm39)	Y103H	probably damaging	Het
Mrpl19	G	T	6: 81,942,796 (GRCm39)	T38K	probably benign	Het
Nefl	A	T	14: 68,321,795 (GRCm39)	K128N	possibly damaging	Het
Olfm1	A	G	2: 28,119,090 (GRCm39)	N242D	probably damaging	Het
Oprd1	T	A	4: 131,844,670 (GRCm39)	T113S	probably damaging	Het
Or10d1	A	T	9: 39,483,877 (GRCm39)	I226N	probably damaging	Het
Or52s19	T	C	7: 103,007,568 (GRCm39)	I278V	probably benign	Het
Pds5b	C	T	5: 150,652,435 (GRCm39)	T234I	possibly damaging	Het
Prpf3	A	T	3: 95,760,792 (GRCm39)	C37S	probably damaging	Het
Rpgrip1l	G	A	8: 92,031,433 (GRCm39)	T148M	possibly damaging	Het
Rph3a	T	C	5: 121,083,509 (GRCm39)	K587R	possibly damaging	Het
Scn3b	T	C	9: 40,188,441 (GRCm39)	C5R	probably damaging	Het
Sirpa	C	T	2: 129,457,372 (GRCm39)	P149S	probably damaging	Het
Slco1a1	A	T	6: 141,864,343 (GRCm39)	C486S	probably damaging	Het
Spin1	C	A	13: 51,277,332 (GRCm39)		probably benign	Het
Stom	C	A	2: 35,211,644 (GRCm39)	V126F	probably damaging	Het
Tom1	A	G	8: 75,783,883 (GRCm39)	D64G	probably damaging	Het
Trbv4	T	A	6: 41,036,613 (GRCm39)	L46Q	probably damaging	Het
Trhr	A	T	15: 44,092,921 (GRCm39)	D386V	possibly damaging	Het
Vmn2r51	C	T	7: 9,832,046 (GRCm39)		probably benign	Het
Vmn2r63	A	G	7: 42,576,274 (GRCm39)		probably null	Het
Zfp277	T	C	12: 40,367,175 (GRCm39)	K494E	probably benign	Het
Zranb3	A	T	1: 127,887,489 (GRCm39)	S979R	probably benign	Het

Other mutations in Vmn2r101

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01121:Vmn2r101	APN	17	19,809,936 (GRCm39)	missense	probably damaging	0.99
IGL02125:Vmn2r101	APN	17	19,809,963 (GRCm39)	missense	possibly damaging	0.95
IGL02300:Vmn2r101	APN	17	19,832,199 (GRCm39)	missense	probably damaging	1.00
IGL02682:Vmn2r101	APN	17	19,832,507 (GRCm39)	missense	possibly damaging	0.82
IGL02862:Vmn2r101	APN	17	19,831,867 (GRCm39)	missense	probably damaging	1.00
IGL02943:Vmn2r101	APN	17	19,831,666 (GRCm39)	missense	probably damaging	0.99
R0371:Vmn2r101	UTSW	17	19,810,394 (GRCm39)	missense	probably benign	0.07
R0462:Vmn2r101	UTSW	17	19,810,431 (GRCm39)	missense	probably benign	0.04
R0492:Vmn2r101	UTSW	17	19,809,245 (GRCm39)	missense	probably damaging	1.00
R0654:Vmn2r101	UTSW	17	19,810,373 (GRCm39)	missense	probably benign	0.01
R1120:Vmn2r101	UTSW	17	19,797,723 (GRCm39)	splice site	probably benign
R1323:Vmn2r101	UTSW	17	19,832,313 (GRCm39)	missense	probably damaging	1.00
R1323:Vmn2r101	UTSW	17	19,832,313 (GRCm39)	missense	probably damaging	1.00
R1676:Vmn2r101	UTSW	17	19,832,184 (GRCm39)	missense	probably benign	0.00
R2023:Vmn2r101	UTSW	17	19,810,368 (GRCm39)	nonsense	probably null
R2149:Vmn2r101	UTSW	17	19,809,225 (GRCm39)	missense	probably benign	0.00
R2350:Vmn2r101	UTSW	17	19,810,045 (GRCm39)	missense	probably benign	0.01
R2760:Vmn2r101	UTSW	17	19,809,901 (GRCm39)	missense	probably benign	0.14
R3085:Vmn2r101	UTSW	17	19,809,077 (GRCm39)	splice site	probably null
R3086:Vmn2r101	UTSW	17	19,809,077 (GRCm39)	splice site	probably null
R3719:Vmn2r101	UTSW	17	19,809,811 (GRCm39)	missense	possibly damaging	0.50
R3771:Vmn2r101	UTSW	17	19,809,919 (GRCm39)	missense	probably benign
R3773:Vmn2r101	UTSW	17	19,809,919 (GRCm39)	missense	probably benign
R4225:Vmn2r101	UTSW	17	19,831,951 (GRCm39)	missense	probably damaging	1.00
R4248:Vmn2r101	UTSW	17	19,809,376 (GRCm39)	missense	probably damaging	1.00
R4290:Vmn2r101	UTSW	17	19,832,303 (GRCm39)	missense	probably damaging	1.00
R4291:Vmn2r101	UTSW	17	19,832,303 (GRCm39)	missense	probably damaging	1.00
R4293:Vmn2r101	UTSW	17	19,832,303 (GRCm39)	missense	probably damaging	1.00
R4307:Vmn2r101	UTSW	17	19,810,423 (GRCm39)	missense	probably damaging	1.00
R4721:Vmn2r101	UTSW	17	19,832,287 (GRCm39)	missense	probably damaging	0.99
R4829:Vmn2r101	UTSW	17	19,832,229 (GRCm39)	missense	probably benign	0.03
R5022:Vmn2r101	UTSW	17	19,831,649 (GRCm39)	critical splice acceptor site	probably null
R5110:Vmn2r101	UTSW	17	19,831,897 (GRCm39)	missense	possibly damaging	0.92
R5244:Vmn2r101	UTSW	17	19,831,788 (GRCm39)	missense	probably damaging	1.00
R5397:Vmn2r101	UTSW	17	19,809,104 (GRCm39)	missense	probably damaging	1.00
R5875:Vmn2r101	UTSW	17	19,809,092 (GRCm39)	missense	probably damaging	0.99
R5944:Vmn2r101	UTSW	17	19,809,769 (GRCm39)	missense	probably benign	0.00
R6216:Vmn2r101	UTSW	17	19,811,267 (GRCm39)	missense	probably benign	0.00
R6334:Vmn2r101	UTSW	17	19,810,112 (GRCm39)	missense	possibly damaging	0.83
R6512:Vmn2r101	UTSW	17	19,809,146 (GRCm39)	missense	probably damaging	1.00
R6607:Vmn2r101	UTSW	17	19,832,296 (GRCm39)	missense	probably damaging	1.00
R6965:Vmn2r101	UTSW	17	19,811,284 (GRCm39)	missense	probably benign	0.00
R7101:Vmn2r101	UTSW	17	19,809,350 (GRCm39)	missense	probably null	0.14
R7183:Vmn2r101	UTSW	17	19,832,440 (GRCm39)	missense	probably damaging	1.00
R7344:Vmn2r101	UTSW	17	19,832,059 (GRCm39)	missense	probably benign	0.38
R7375:Vmn2r101	UTSW	17	19,831,652 (GRCm39)	missense	probably damaging	1.00
R7574:Vmn2r101	UTSW	17	19,831,899 (GRCm39)	missense	possibly damaging	0.91
R7575:Vmn2r101	UTSW	17	19,831,654 (GRCm39)	missense	probably benign	0.01
R7592:Vmn2r101	UTSW	17	19,811,443 (GRCm39)	splice site	probably null
R7626:Vmn2r101	UTSW	17	19,832,192 (GRCm39)	nonsense	probably null
R7715:Vmn2r101	UTSW	17	19,832,177 (GRCm39)	missense	probably damaging	1.00
R7730:Vmn2r101	UTSW	17	19,831,950 (GRCm39)	missense	possibly damaging	0.81
R8078:Vmn2r101	UTSW	17	19,810,507 (GRCm39)	missense	probably benign	0.07
R8228:Vmn2r101	UTSW	17	19,811,284 (GRCm39)	missense	probably benign	0.00
R8283:Vmn2r101	UTSW	17	19,832,253 (GRCm39)	missense	probably damaging	1.00
R8712:Vmn2r101	UTSW	17	19,811,397 (GRCm39)	missense	probably benign	0.24
R8765:Vmn2r101	UTSW	17	19,809,245 (GRCm39)	missense	probably damaging	1.00
R9091:Vmn2r101	UTSW	17	19,810,244 (GRCm39)	missense	probably benign
R9092:Vmn2r101	UTSW	17	19,809,807 (GRCm39)	missense	probably benign	0.07
R9113:Vmn2r101	UTSW	17	19,811,288 (GRCm39)	missense	possibly damaging	0.56
R9158:Vmn2r101	UTSW	17	19,809,161 (GRCm39)	missense	probably benign	0.00
R9168:Vmn2r101	UTSW	17	19,809,138 (GRCm39)	missense	probably damaging	1.00
R9235:Vmn2r101	UTSW	17	19,810,238 (GRCm39)	missense	probably damaging	0.99
R9270:Vmn2r101	UTSW	17	19,810,244 (GRCm39)	missense	probably benign
R9290:Vmn2r101	UTSW	17	19,811,395 (GRCm39)	missense	probably benign	0.05
R9296:Vmn2r101	UTSW	17	19,810,047 (GRCm39)	missense	probably damaging	0.98
R9602:Vmn2r101	UTSW	17	19,831,780 (GRCm39)	nonsense	probably null
R9706:Vmn2r101	UTSW	17	19,809,925 (GRCm39)	missense	probably damaging	1.00
Z1088:Vmn2r101	UTSW	17	19,809,237 (GRCm39)	missense	possibly damaging	0.78

Posted On

2015-12-18