Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02827:Ifitm10'

361249

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ifitm10

Ensembl Gene

ENSMUSG00000045777

Gene Name

interferon induced transmembrane protein 10

Synonyms

6330512M04Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.072) question?

Stock #

IGL02827

Quality Score

Status

Chromosome

Chromosomal Location

141879574-141927490 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 141882317 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 151 (D151G)

Ref Sequence

ENSEMBL: ENSMUSP00000062728 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000059223]

AlphaFold

Q8BR26

Predicted Effect

unknown
Transcript: ENSMUST00000059223
AA Change: D151G

SMART Domains

Protein: ENSMUSP00000062728
Gene: ENSMUSG00000045777
AA Change: D151G

Domain	Start	End	E-Value	Type
Pfam:Dispanin	38	108	6.5e-12	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000131791

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000140032

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 32 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca7	T	C	10: 79,845,699 (GRCm39)	S1554P	probably damaging	Het
Actn2	A	T	13: 12,290,085 (GRCm39)	L152Q	probably damaging	Het
Afg3l2	T	C	18: 67,559,015 (GRCm39)	I369V	probably damaging	Het
Aqp6	G	A	15: 99,500,892 (GRCm39)	G199S	probably damaging	Het
Asgr2	A	G	11: 69,987,723 (GRCm39)	I74V	probably benign	Het
Cebpz	T	C	17: 79,236,760 (GRCm39)	R702G	probably damaging	Het
Cers1	C	T	8: 70,774,177 (GRCm39)	P145S	probably damaging	Het
Ddx21	T	C	10: 62,434,153 (GRCm39)	K202R	probably benign	Het
Gphn	A	T	12: 78,655,994 (GRCm39)	D407V	probably damaging	Het
Hnf1b	A	G	11: 83,746,752 (GRCm39)	K123E	probably damaging	Het
Ifna14	T	A	4: 88,489,601 (GRCm39)	K145N	probably benign	Het
Lamc2	C	T	1: 153,015,527 (GRCm39)	C602Y	probably damaging	Het
Mrps25	T	C	6: 92,152,163 (GRCm39)	E119G	probably benign	Het
Or10ak9	A	T	4: 118,726,157 (GRCm39)	M60L	probably damaging	Het
Or1f12	A	G	13: 21,721,528 (GRCm39)	S216P	probably benign	Het
Pgm5	C	A	19: 24,686,659 (GRCm39)	R516L	probably benign	Het
Pramel31	C	T	4: 144,090,331 (GRCm39)	A457V	probably damaging	Het
Rmnd5b	A	G	11: 51,518,849 (GRCm39)	L48P	possibly damaging	Het
Samd4b	G	A	7: 28,113,546 (GRCm39)	R140C	probably damaging	Het
Sema3d	T	C	5: 12,635,085 (GRCm39)	I717T	probably benign	Het
Sh3tc2	G	A	18: 62,146,230 (GRCm39)	S1203N	probably benign	Het
Smpdl3a	A	G	10: 57,678,592 (GRCm39)	T132A	probably damaging	Het
Stard13	T	C	5: 150,986,591 (GRCm39)	I188M	probably benign	Het
Stk17b	T	C	1: 53,815,701 (GRCm39)	T33A	probably benign	Het
Stxbp3	A	T	3: 108,717,211 (GRCm39)	I264N	probably damaging	Het
Tmem60	T	A	5: 21,091,622 (GRCm39)	F129Y	probably damaging	Het
Trpm1	A	G	7: 63,868,908 (GRCm39)	D404G	probably null	Het
Unc79	A	C	12: 103,041,105 (GRCm39)	S713R	possibly damaging	Het
Uox	A	C	3: 146,302,951 (GRCm39)		probably benign	Het
Vmn2r68	T	C	7: 84,886,800 (GRCm39)	D38G	probably damaging	Het
Vps13a	T	C	19: 16,618,998 (GRCm39)	D2856G	possibly damaging	Het
Vsig10l	T	C	7: 43,114,293 (GRCm39)	L205P	probably damaging	Het

Other mutations in Ifitm10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R0647:Ifitm10	UTSW	7	141,909,772 (GRCm39)	missense	probably damaging	0.99
R2044:Ifitm10	UTSW	7	141,909,771 (GRCm39)	missense	probably damaging	1.00
R3785:Ifitm10	UTSW	7	141,882,335 (GRCm39)	missense	possibly damaging	0.56
R7203:Ifitm10	UTSW	7	141,882,305 (GRCm39)	missense	probably benign	0.06
R8077:Ifitm10	UTSW	7	141,924,704 (GRCm39)	missense	probably damaging	1.00
R8677:Ifitm10	UTSW	7	141,909,749 (GRCm39)	missense	probably benign	0.20
R8954:Ifitm10	UTSW	7	141,882,300 (GRCm39)	missense	probably benign	0.07
R9393:Ifitm10	UTSW	7	141,924,704 (GRCm39)	missense	probably damaging	1.00
R9394:Ifitm10	UTSW	7	141,924,704 (GRCm39)	missense	probably damaging	1.00
R9395:Ifitm10	UTSW	7	141,924,704 (GRCm39)	missense	probably damaging	1.00
R9396:Ifitm10	UTSW	7	141,924,704 (GRCm39)	missense	probably damaging	1.00
R9486:Ifitm10	UTSW	7	141,909,812 (GRCm39)	missense	probably damaging	1.00
R9630:Ifitm10	UTSW	7	141,924,909 (GRCm39)	missense	probably damaging	0.99
RF008:Ifitm10	UTSW	7	141,882,330 (GRCm39)	missense	unknown

Posted On

2015-12-18