Incidental Mutation 'IGL02829:Yipf7'
ID361342
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Yipf7
Ensembl Gene ENSMUSG00000029158
Gene NameYip1 domain family, member 7
Synonyms2310016N21Rik, Yip1b
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL02829
Quality Score
Status
Chromosome5
Chromosomal Location69516671-69542648 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 69541091 bp
ZygosityHeterozygous
Amino Acid Change Serine to Arginine at position 24 (S24R)
Ref Sequence ENSEMBL: ENSMUSP00000031045 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000031045] [ENSMUST00000202423]
Predicted Effect probably benign
Transcript: ENSMUST00000031045
AA Change: S24R

PolyPhen 2 Score 0.217 (Sensitivity: 0.91; Specificity: 0.88)
SMART Domains Protein: ENSMUSP00000031045
Gene: ENSMUSG00000029158
AA Change: S24R

DomainStartEndE-ValueType
Pfam:Yip1 93 253 4.2e-13 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000202423
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 38 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Bbs9 A G 9: 22,579,484 T303A probably damaging Het
Bet1 T A 6: 4,086,795 M1L probably benign Het
Bicc1 A C 10: 70,958,880 V149G probably damaging Het
Braf C A 6: 39,627,728 L655F possibly damaging Het
Cd101 A G 3: 101,018,565 probably benign Het
Cobll1 T C 2: 65,126,045 K290E probably damaging Het
Col6a5 A T 9: 105,934,307 I671K unknown Het
D130052B06Rik A C 11: 33,623,864 T154P probably benign Het
Dglucy A C 12: 100,871,404 H602P probably damaging Het
Fbxo34 A G 14: 47,529,689 I220V probably benign Het
Gm42878 A G 5: 121,537,203 V101A probably damaging Het
Gsdmc4 A G 15: 63,892,648 L381P probably benign Het
Ifi208 C A 1: 173,682,840 P187H probably damaging Het
Lrrc37a A T 11: 103,491,174 C2473S unknown Het
Miip T A 4: 147,863,061 N214I probably benign Het
Mrc2 A G 11: 105,336,707 T589A possibly damaging Het
Mtss1 A G 15: 59,058,428 probably benign Het
Mypn T C 10: 63,192,586 R233G probably benign Het
Naip6 A T 13: 100,300,765 C417S probably benign Het
Olfr1084 T A 2: 86,639,255 Y151F possibly damaging Het
Olfr1216 A C 2: 89,013,677 L129W probably damaging Het
Olfr275 C T 4: 52,826,027 P210L probably damaging Het
Pcsk1 T C 13: 75,126,836 Y515H probably damaging Het
Pla2g2e T A 4: 138,880,436 Y42* probably null Het
Polh A T 17: 46,172,902 L479Q possibly damaging Het
Prr36 T A 8: 4,215,278 R157S possibly damaging Het
Reck T A 4: 43,891,014 C51S probably damaging Het
Rev3l A G 10: 39,825,240 D1911G probably damaging Het
Scgb1b27 A T 7: 34,021,748 probably null Het
Sema4g G A 19: 44,992,749 R47Q possibly damaging Het
Serinc1 A T 10: 57,523,965 Y158* probably null Het
Slc15a2 C A 16: 36,757,193 G435C possibly damaging Het
Tbc1d17 C A 7: 44,848,872 probably benign Het
Tenm4 C T 7: 96,894,998 Q2074* probably null Het
Tns3 A G 11: 8,519,564 C244R probably damaging Het
Vmn2r2 A T 3: 64,118,751 probably benign Het
Vmn2r44 T A 7: 8,377,880 Q338L possibly damaging Het
Wdr70 C T 15: 7,976,982 D363N possibly damaging Het
Other mutations in Yipf7
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01160:Yipf7 APN 5 69519317 missense probably benign 0.13
R0581:Yipf7 UTSW 5 69521063 missense probably benign 0.37
R2104:Yipf7 UTSW 5 69521119 missense possibly damaging 0.92
R2697:Yipf7 UTSW 5 69541140 missense possibly damaging 0.79
R4329:Yipf7 UTSW 5 69521122 missense probably damaging 1.00
R4621:Yipf7 UTSW 5 69519361 missense possibly damaging 0.79
R6103:Yipf7 UTSW 5 69541062 missense probably benign
R6652:Yipf7 UTSW 5 69541161 start codon destroyed probably null 1.00
R6823:Yipf7 UTSW 5 69517070 missense probably damaging 1.00
R7674:Yipf7 UTSW 5 69519229 missense probably damaging 0.99
R7796:Yipf7 UTSW 5 69527253 missense possibly damaging 0.85
Posted On2015-12-18