Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02834:Vmn2r51'

361556

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r51

Ensembl Gene

ENSMUSG00000058685

Gene Name

vomeronasal 2, receptor 51

Synonyms

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.069) question?

Stock #

IGL02834

Quality Score

Status

Chromosome

Chromosomal Location

10087198-10105659 bp(-) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

T to A at 10098136 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Arginine to Stop codon at position 508 (R508*)

Ref Sequence

ENSEMBL: ENSMUSP00000092459 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094863]

AlphaFold

L7N215

Predicted Effect

probably null
Transcript: ENSMUST00000094863
AA Change: R508*

SMART Domains

Protein: ENSMUSP00000092459
Gene: ENSMUSG00000058685
AA Change: R508*

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:ANF_receptor	73	469	2.4e-31	PFAM
Pfam:NCD3G	512	565	8.1e-21	PFAM
Pfam:7tm_3	598	833	2.7e-54	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 26 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A530099J19Rik	A	T	13: 19,729,875		noncoding transcript	Het
Arhgap10	A	T	8: 77,365,100	L430Q	probably damaging	Het
Cc2d2a	C	T	5: 43,714,521	R900*	probably null	Het
Cd14	A	G	18: 36,725,503	Y300H	probably benign	Het
Dgcr8	T	A	16: 18,272,759	T584S	probably benign	Het
Epb41l5	C	T	1: 119,623,955	G100D	probably benign	Het
Fat4	G	A	3: 38,956,744	G1998R	probably damaging	Het
Fndc3b	A	T	3: 27,508,503	L279H	probably damaging	Het
Gabrr1	A	G	4: 33,151,426	E114G	probably damaging	Het
Hrh2	A	G	13: 54,215,000	R332G	probably benign	Het
Kif5a	T	C	10: 127,245,756	I180V	probably benign	Het
Lyg2	T	A	1: 37,909,967	R105W	probably damaging	Het
Myc	A	G	15: 61,987,666	I64V	probably damaging	Het
Nrcam	G	A	12: 44,541,075		probably null	Het
Ogdhl	A	G	14: 32,325,946	Y51C	probably damaging	Het
Olfr1339	C	T	4: 118,734,606	L26F	probably benign	Het
Olfr631	T	A	7: 103,929,394	C190*	probably null	Het
Pdlim3	A	G	8: 45,917,532	R290G	probably benign	Het
Ppm1l	G	A	3: 69,549,343	A198T	probably damaging	Het
Prkd2	A	G	7: 16,845,934	D119G	probably damaging	Het
Rapgef3	A	T	15: 97,748,265	I820N	probably damaging	Het
Scnn1b	A	G	7: 121,912,062	Y324C	probably damaging	Het
Smc5	G	A	19: 23,257,604	R289C	probably benign	Het
Vps13c	A	T	9: 67,937,855	I2074L	probably benign	Het
Wdr64	T	C	1: 175,805,849		probably benign	Het
Ydjc	C	T	16: 17,147,289	P74L	probably benign	Het

Other mutations in Vmn2r51

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01398:Vmn2r51	APN	7	10102414	missense	probably benign
IGL01574:Vmn2r51	APN	7	10102454	missense	probably damaging	1.00
IGL01743:Vmn2r51	APN	7	10100227	missense	probably damaging	0.98
IGL01820:Vmn2r51	APN	7	10105482	missense	probably damaging	1.00
IGL02563:Vmn2r51	APN	7	10100316	missense	probably benign	0.00
IGL02825:Vmn2r51	APN	7	10098119	splice site	probably benign
R0617:Vmn2r51	UTSW	7	10100469	missense	possibly damaging	0.65
R0967:Vmn2r51	UTSW	7	10100085	missense	probably damaging	0.97
R1465:Vmn2r51	UTSW	7	10100322	missense	probably damaging	1.00
R1465:Vmn2r51	UTSW	7	10100322	missense	probably damaging	1.00
R1559:Vmn2r51	UTSW	7	10102445	missense	possibly damaging	0.58
R1559:Vmn2r51	UTSW	7	10102446	missense	possibly damaging	0.87
R1598:Vmn2r51	UTSW	7	10105505	missense	probably benign
R1754:Vmn2r51	UTSW	7	10099946	missense	probably benign	0.04
R1836:Vmn2r51	UTSW	7	10098163	nonsense	probably null
R1836:Vmn2r51	UTSW	7	10098164	nonsense	probably null
R3151:Vmn2r51	UTSW	7	10100041	missense	probably damaging	1.00
R4566:Vmn2r51	UTSW	7	10102414	missense	probably benign
R4933:Vmn2r51	UTSW	7	10098320	missense	probably damaging	1.00
R5004:Vmn2r51	UTSW	7	10088005	missense	probably benign
R5050:Vmn2r51	UTSW	7	10100422	missense	probably damaging	0.99
R5510:Vmn2r51	UTSW	7	10102618	missense	possibly damaging	0.95
R5559:Vmn2r51	UTSW	7	10092201	missense	probably damaging	1.00
R6127:Vmn2r51	UTSW	7	10105631	missense	probably damaging	1.00
R6154:Vmn2r51	UTSW	7	10087994	missense	possibly damaging	0.74
R6304:Vmn2r51	UTSW	7	10098237	missense	probably benign	0.00
R6370:Vmn2r51	UTSW	7	10098216	missense	probably damaging	1.00
R6471:Vmn2r51	UTSW	7	10102583	missense	possibly damaging	0.48
R6800:Vmn2r51	UTSW	7	10098264	missense	probably damaging	0.99
R6883:Vmn2r51	UTSW	7	10100098	missense	possibly damaging	0.75
R7191:Vmn2r51	UTSW	7	10100553	missense	probably null	1.00
R7246:Vmn2r51	UTSW	7	10102501	missense	probably benign	0.00
R8939:Vmn2r51	UTSW	7	10100026	missense	possibly damaging	0.85
R9154:Vmn2r51	UTSW	7	10105553	missense	probably damaging	0.96
R9428:Vmn2r51	UTSW	7	10099785	critical splice donor site	probably benign
Z1176:Vmn2r51	UTSW	7	10088057	missense	possibly damaging	0.76
Z1176:Vmn2r51	UTSW	7	10099908	missense	probably benign	0.12

Posted On

2015-12-18