Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02834:Vmn2r51'

361556

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r51

Ensembl Gene

ENSMUSG00000058685

Gene Name

vomeronasal 2, receptor 51

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.079) question?

Stock #

IGL02834

Quality Score

Status

Chromosome

Chromosomal Location

10087198-10105659 bp(-) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

T to A at 10098136 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Arginine to Stop codon at position 508 (R508*)

Ref Sequence

ENSEMBL: ENSMUSP00000092459 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094863]

AlphaFold

L7N215

Predicted Effect

probably null
Transcript: ENSMUST00000094863
AA Change: R508*

SMART Domains

Protein: ENSMUSP00000092459
Gene: ENSMUSG00000058685
AA Change: R508*

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
Pfam:ANF_receptor	73	469	2.4e-31	PFAM
Pfam:NCD3G	512	565	8.1e-21	PFAM
Pfam:7tm_3	598	833	2.7e-54	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 26 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A530099J19Rik	A	T	13: 19,729,875		noncoding transcript	Het
Arhgap10	A	T	8: 77,365,100	L430Q	probably damaging	Het
Cc2d2a	C	T	5: 43,714,521	R900*	probably null	Het
Cd14	A	G	18: 36,725,503	Y300H	probably benign	Het
Dgcr8	T	A	16: 18,272,759	T584S	probably benign	Het
Epb41l5	C	T	1: 119,623,955	G100D	probably benign	Het
Fat4	G	A	3: 38,956,744	G1998R	probably damaging	Het
Fndc3b	A	T	3: 27,508,503	L279H	probably damaging	Het
Gabrr1	A	G	4: 33,151,426	E114G	probably damaging	Het
Hrh2	A	G	13: 54,215,000	R332G	probably benign	Het
Kif5a	T	C	10: 127,245,756	I180V	probably benign	Het
Lyg2	T	A	1: 37,909,967	R105W	probably damaging	Het
Myc	A	G	15: 61,987,666	I64V	probably damaging	Het
Nrcam	G	A	12: 44,541,075		probably null	Het
Ogdhl	A	G	14: 32,325,946	Y51C	probably damaging	Het
Olfr1339	C	T	4: 118,734,606	L26F	probably benign	Het
Olfr631	T	A	7: 103,929,394	C190*	probably null	Het
Pdlim3	A	G	8: 45,917,532	R290G	probably benign	Het
Ppm1l	G	A	3: 69,549,343	A198T	probably damaging	Het
Prkd2	A	G	7: 16,845,934	D119G	probably damaging	Het
Rapgef3	A	T	15: 97,748,265	I820N	probably damaging	Het
Scnn1b	A	G	7: 121,912,062	Y324C	probably damaging	Het
Smc5	G	A	19: 23,257,604	R289C	probably benign	Het
Vps13c	A	T	9: 67,937,855	I2074L	probably benign	Het
Wdr64	T	C	1: 175,805,849		probably benign	Het
Ydjc	C	T	16: 17,147,289	P74L	probably benign	Het

Other mutations in Vmn2r51

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01398:Vmn2r51	APN	7	10102414	missense	probably benign
IGL01574:Vmn2r51	APN	7	10102454	missense	probably damaging	1.00
IGL01743:Vmn2r51	APN	7	10100227	missense	probably damaging	0.98
IGL01820:Vmn2r51	APN	7	10105482	missense	probably damaging	1.00
IGL02563:Vmn2r51	APN	7	10100316	missense	probably benign	0.00
IGL02825:Vmn2r51	APN	7	10098119	splice site	probably benign
R0617:Vmn2r51	UTSW	7	10100469	missense	possibly damaging	0.65
R0967:Vmn2r51	UTSW	7	10100085	missense	probably damaging	0.97
R1465:Vmn2r51	UTSW	7	10100322	missense	probably damaging	1.00
R1465:Vmn2r51	UTSW	7	10100322	missense	probably damaging	1.00
R1559:Vmn2r51	UTSW	7	10102445	missense	possibly damaging	0.58
R1559:Vmn2r51	UTSW	7	10102446	missense	possibly damaging	0.87
R1598:Vmn2r51	UTSW	7	10105505	missense	probably benign
R1754:Vmn2r51	UTSW	7	10099946	missense	probably benign	0.04
R1836:Vmn2r51	UTSW	7	10098163	nonsense	probably null
R1836:Vmn2r51	UTSW	7	10098164	nonsense	probably null
R3151:Vmn2r51	UTSW	7	10100041	missense	probably damaging	1.00
R4566:Vmn2r51	UTSW	7	10102414	missense	probably benign
R4933:Vmn2r51	UTSW	7	10098320	missense	probably damaging	1.00
R5004:Vmn2r51	UTSW	7	10088005	missense	probably benign
R5050:Vmn2r51	UTSW	7	10100422	missense	probably damaging	0.99
R5510:Vmn2r51	UTSW	7	10102618	missense	possibly damaging	0.95
R5559:Vmn2r51	UTSW	7	10092201	missense	probably damaging	1.00
R6127:Vmn2r51	UTSW	7	10105631	missense	probably damaging	1.00
R6154:Vmn2r51	UTSW	7	10087994	missense	possibly damaging	0.74
R6304:Vmn2r51	UTSW	7	10098237	missense	probably benign	0.00
R6370:Vmn2r51	UTSW	7	10098216	missense	probably damaging	1.00
R6471:Vmn2r51	UTSW	7	10102583	missense	possibly damaging	0.48
R6800:Vmn2r51	UTSW	7	10098264	missense	probably damaging	0.99
R6883:Vmn2r51	UTSW	7	10100098	missense	possibly damaging	0.75
R7191:Vmn2r51	UTSW	7	10100553	missense	probably null	1.00
R7246:Vmn2r51	UTSW	7	10102501	missense	probably benign	0.00
R8939:Vmn2r51	UTSW	7	10100026	missense	possibly damaging	0.85
R9154:Vmn2r51	UTSW	7	10105553	missense	probably damaging	0.96
R9428:Vmn2r51	UTSW	7	10099785	critical splice donor site	probably benign
R9451:Vmn2r51	UTSW	7	10099889	missense	probably damaging	1.00
R9729:Vmn2r51	UTSW	7	10105552	missense	probably benign	0.00
R9767:Vmn2r51	UTSW	7	10105480	missense	probably benign	0.09
Z1176:Vmn2r51	UTSW	7	10088057	missense	possibly damaging	0.76
Z1176:Vmn2r51	UTSW	7	10099908	missense	probably benign	0.12

Posted On

2015-12-18