Incidental Mutation 'IGL02836:Zfp438'
ID361681
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zfp438
Ensembl Gene ENSMUSG00000050945
Gene Namezinc finger protein 438
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.106) question?
Stock #IGL02836
Quality Score
Status
Chromosome18
Chromosomal Location5210031-5334439 bp(-) (GRCm38)
Type of Mutationutr 5 prime
DNA Base Change (assembly) A to G at 5245427 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000067049 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000063989]
Predicted Effect probably benign
Transcript: ENSMUST00000063989
SMART Domains Protein: ENSMUSP00000067049
Gene: ENSMUSG00000050945

DomainStartEndE-ValueType
low complexity region 132 151 N/A INTRINSIC
low complexity region 263 274 N/A INTRINSIC
low complexity region 427 439 N/A INTRINSIC
ZnF_C2H2 493 515 5.72e-1 SMART
ZnF_C2H2 521 543 7.26e-3 SMART
ZnF_C2H2 553 576 5.2e0 SMART
ZnF_C2H2 635 658 1.86e1 SMART
ZnF_C2H2 746 769 1.13e1 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 52 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aadacl4 T A 4: 144,623,212 N346K possibly damaging Het
Abca15 A G 7: 120,388,216 M1242V probably benign Het
Abca6 T A 11: 110,248,548 E33D probably damaging Het
Abca8a T C 11: 110,070,351 K582E possibly damaging Het
Abcb6 A G 1: 75,178,002 L263P probably damaging Het
Adamts2 A C 11: 50,787,279 E795A probably damaging Het
Avil T A 10: 127,008,995 I292N probably damaging Het
Ccdc129 T A 6: 55,898,090 W342R probably damaging Het
Cd300ld2 T C 11: 115,013,750 D97G probably benign Het
Cfh A C 1: 140,102,399 I912R probably damaging Het
Cyp26c1 A T 19: 37,687,156 Q156L probably benign Het
Dhx57 T C 17: 80,267,549 I614V probably damaging Het
Dip2c T A 13: 9,610,790 S896T probably damaging Het
Dmtn G T 14: 70,616,078 P97Q probably damaging Het
Dock6 A T 9: 21,801,864 V1931E probably damaging Het
Dpep2 C A 8: 105,990,595 probably null Het
Dsg1c T A 18: 20,267,929 L163Q probably benign Het
Esyt3 A G 9: 99,320,907 probably benign Het
Fcgbp T A 7: 28,117,358 I2415N possibly damaging Het
Fpr-rs6 T C 17: 20,183,045 D18G probably benign Het
Fras1 T C 5: 96,534,866 V74A possibly damaging Het
Frem3 T C 8: 80,614,381 V1101A probably benign Het
Fut8 T A 12: 77,450,213 V399E probably benign Het
Galntl5 G T 5: 25,186,239 K45N probably benign Het
Gbe1 A G 16: 70,561,095 Y669C possibly damaging Het
Gcnt1 T C 19: 17,330,129 I77M probably benign Het
Mark2 A G 19: 7,278,040 probably null Het
Muc2 A T 7: 141,746,713 probably benign Het
Nacc2 C T 2: 26,090,317 V36I probably damaging Het
Nphp1 T C 2: 127,769,623 I268V probably benign Het
Olfr1154 T G 2: 87,903,380 T99P possibly damaging Het
Oosp3 A G 19: 11,700,968 I5V probably benign Het
Pex7 A G 10: 19,894,244 probably benign Het
Prr14l T C 5: 32,831,096 K352E probably benign Het
Rheb T A 5: 24,803,711 I170F probably benign Het
Rpgrip1 A G 14: 52,145,257 probably null Het
Rps2 T A 17: 24,720,676 L107Q probably damaging Het
Rrp1 A T 10: 78,405,040 probably benign Het
Rtcb A T 10: 85,943,942 V288D possibly damaging Het
Sec14l3 T C 11: 4,070,084 F174L probably benign Het
Slc28a1 G A 7: 81,126,161 V202M probably damaging Het
Slc44a3 A T 3: 121,531,717 C32S probably damaging Het
Syne1 G A 10: 5,409,875 probably benign Het
Synrg C A 11: 84,001,978 probably benign Het
Tmem219 A T 7: 126,888,949 F265I probably benign Het
Tmem94 T C 11: 115,792,939 I726T probably damaging Het
Trim37 T C 11: 87,196,959 M632T probably benign Het
Trpm6 A T 19: 18,813,482 Q627L probably damaging Het
Uvrag A G 7: 98,979,777 V361A possibly damaging Het
Yipf3 C A 17: 46,251,594 N308K possibly damaging Het
Zmiz1 T A 14: 25,656,742 probably benign Het
Zranb3 A G 1: 127,960,825 V841A probably benign Het
Other mutations in Zfp438
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01907:Zfp438 APN 18 5213815 missense probably damaging 1.00
IGL01967:Zfp438 APN 18 5214049 missense probably benign 0.00
IGL02003:Zfp438 APN 18 5214503 missense probably benign 0.15
IGL02305:Zfp438 APN 18 5213674 missense possibly damaging 0.84
IGL02439:Zfp438 APN 18 5213216 missense probably damaging 1.00
IGL02744:Zfp438 APN 18 5214760 missense probably benign 0.03
R0308:Zfp438 UTSW 18 5213638 missense probably benign 0.00
R0437:Zfp438 UTSW 18 5214910 missense probably damaging 0.97
R1540:Zfp438 UTSW 18 5210740 missense probably benign 0.04
R1594:Zfp438 UTSW 18 5213515 missense possibly damaging 0.94
R1804:Zfp438 UTSW 18 5213689 missense probably damaging 1.00
R2057:Zfp438 UTSW 18 5214085 missense probably benign 0.03
R2256:Zfp438 UTSW 18 5213508 missense probably damaging 0.99
R4549:Zfp438 UTSW 18 5214073 missense probably benign 0.01
R4747:Zfp438 UTSW 18 5214403 missense probably benign 0.00
R4858:Zfp438 UTSW 18 5213154 missense probably benign 0.01
R4887:Zfp438 UTSW 18 5213776 missense possibly damaging 0.55
R5543:Zfp438 UTSW 18 5213761 missense probably damaging 1.00
R5646:Zfp438 UTSW 18 5214526 missense probably benign 0.36
R6022:Zfp438 UTSW 18 5213419 missense probably damaging 1.00
R6058:Zfp438 UTSW 18 5213209 missense probably damaging 1.00
R6460:Zfp438 UTSW 18 5213603 missense probably damaging 1.00
R6703:Zfp438 UTSW 18 5214044 missense probably benign 0.05
R6766:Zfp438 UTSW 18 5213780 missense probably benign 0.07
R7252:Zfp438 UTSW 18 5214874 nonsense probably null
R7283:Zfp438 UTSW 18 5214712 missense probably damaging 1.00
R7429:Zfp438 UTSW 18 5214139 missense probably benign 0.01
R7769:Zfp438 UTSW 18 5213377 missense possibly damaging 0.93
R8139:Zfp438 UTSW 18 5214013 missense probably benign 0.01
R8291:Zfp438 UTSW 18 5211010 nonsense probably null
Posted On2015-12-18