Incidental Mutation 'IGL02859:Bivm'
ID362088
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Bivm
Ensembl Gene ENSMUSG00000041684
Gene Namebasic, immunoglobulin-like variable motif containing
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.079) question?
Stock #IGL02859
Quality Score
Status
Chromosome1
Chromosomal Location44118957-44144770 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) C to A at 44136999 bp
ZygosityHeterozygous
Amino Acid Change Serine to Stop codon at position 305 (S305*)
Ref Sequence ENSEMBL: ENSMUSP00000110357 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000035991] [ENSMUST00000114709]
Predicted Effect probably null
Transcript: ENSMUST00000035991
AA Change: S305*
SMART Domains Protein: ENSMUSP00000041964
Gene: ENSMUSG00000041684
AA Change: S305*

DomainStartEndE-ValueType
low complexity region 117 129 N/A INTRINSIC
low complexity region 162 174 N/A INTRINSIC
Blast:XPGN 456 501 3e-11 BLAST
Predicted Effect probably null
Transcript: ENSMUST00000114709
AA Change: S305*
SMART Domains Protein: ENSMUSP00000110357
Gene: ENSMUSG00000041684
AA Change: S305*

DomainStartEndE-ValueType
low complexity region 117 129 N/A INTRINSIC
low complexity region 162 174 N/A INTRINSIC
Blast:XPGN 456 501 3e-11 BLAST
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 39 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2210408I21Rik A T 13: 77,267,699 Y637F possibly damaging Het
Abcc4 A G 14: 118,516,500 I1025T probably damaging Het
Adam22 C A 5: 8,167,375 R140L probably damaging Het
Ahdc1 T A 4: 133,062,693 L415H probably damaging Het
Ahdc1 C A 4: 133,062,692 L415I possibly damaging Het
Clca4b C T 3: 144,912,039 D768N probably benign Het
Cobl T A 11: 12,369,602 N31Y probably damaging Het
Col4a5 G A X: 141,609,850 C484Y unknown Het
Ctnnd1 T C 2: 84,619,909 probably benign Het
Dnah5 A G 15: 28,383,625 T2998A probably benign Het
Dnah9 T A 11: 65,881,619 probably benign Het
F2 T C 2: 91,625,742 D558G probably damaging Het
Gle1 T A 2: 29,949,228 W511R probably damaging Het
Gm11564 C T 11: 99,815,127 S159N unknown Het
Htr6 A G 4: 139,074,434 C110R probably damaging Het
Ikbke T A 1: 131,270,197 S391C probably damaging Het
Itgae T C 11: 73,114,867 F286L probably damaging Het
Kcnb2 A T 1: 15,710,506 H534L probably damaging Het
Map1b T C 13: 99,433,036 Y1059C unknown Het
Mul1 A G 4: 138,438,349 T106A probably damaging Het
Nf2 T A 11: 4,791,209 E249V probably damaging Het
Nlrp1a T C 11: 71,106,086 S965G possibly damaging Het
Nrn1 C A 13: 36,730,106 probably null Het
Olfr1084 T C 2: 86,639,648 N20S probably benign Het
Olfr583 T C 7: 103,052,138 V280A probably benign Het
Optc T C 1: 133,902,061 T204A probably damaging Het
Pcnx2 C T 8: 125,863,173 R787Q probably damaging Het
Pim1 G A 17: 29,491,935 E171K probably damaging Het
Pnpt1 T C 11: 29,138,162 V191A probably damaging Het
Rbbp8 G A 18: 11,738,614 R796Q probably benign Het
Serpinb9e A G 13: 33,251,650 D22G possibly damaging Het
Sit1 C T 4: 43,482,831 M109I probably benign Het
Slc17a8 A G 10: 89,576,584 V329A probably benign Het
Smg1 T A 7: 118,148,933 probably benign Het
Snx7 T A 3: 117,829,671 probably benign Het
Stat2 A T 10: 128,276,611 E40V probably damaging Het
Vegfa C T 17: 46,024,495 S291N probably benign Het
Vmn1r61 G T 7: 5,611,289 L9I probably benign Het
Wbp4 T C 14: 79,470,689 K163E probably damaging Het
Other mutations in Bivm
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01090:Bivm APN 1 44129291 missense probably damaging 1.00
IGL01384:Bivm APN 1 44126747 missense possibly damaging 0.86
IGL01552:Bivm APN 1 44126773 missense probably benign 0.40
IGL01736:Bivm APN 1 44141813 missense probably damaging 1.00
IGL02332:Bivm APN 1 44128720 unclassified probably benign
IGL02704:Bivm APN 1 44126446 missense probably benign
IGL02939:Bivm APN 1 44142960 missense probably benign 0.03
IGL03265:Bivm APN 1 44141845 missense probably damaging 1.00
R0456:Bivm UTSW 1 44126809 missense probably damaging 1.00
R1172:Bivm UTSW 1 44126782 missense probably benign 0.04
R1173:Bivm UTSW 1 44126782 missense probably benign 0.04
R1174:Bivm UTSW 1 44126782 missense probably benign 0.04
R1177:Bivm UTSW 1 44142963 missense probably benign 0.28
R1350:Bivm UTSW 1 44126703 missense possibly damaging 0.88
R1611:Bivm UTSW 1 44126747 missense possibly damaging 0.92
R2518:Bivm UTSW 1 44129615 missense probably damaging 0.96
R3735:Bivm UTSW 1 44126434 missense probably benign 0.07
R4290:Bivm UTSW 1 44138633 missense probably damaging 1.00
R4292:Bivm UTSW 1 44138633 missense probably damaging 1.00
R4293:Bivm UTSW 1 44138633 missense probably damaging 1.00
R4294:Bivm UTSW 1 44138633 missense probably damaging 1.00
R4849:Bivm UTSW 1 44142873 missense possibly damaging 0.70
R5204:Bivm UTSW 1 44138578 missense probably damaging 0.96
R5912:Bivm UTSW 1 44126413 nonsense probably null
R6045:Bivm UTSW 1 44119073 start gained probably benign
R6216:Bivm UTSW 1 44126868 critical splice donor site probably null
R6836:Bivm UTSW 1 44143136 missense possibly damaging 0.88
R7120:Bivm UTSW 1 44126446 missense probably benign
R7817:Bivm UTSW 1 44126401 missense probably benign 0.01
Posted On2015-12-18