Incidental Mutation 'IGL02865:Zfp938'
ID362317
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zfp938
Ensembl Gene ENSMUSG00000062931
Gene Namezinc finger protein 938
SynonymsB230315N10Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.073) question?
Stock #IGL02865
Quality Score
Status
Chromosome10
Chromosomal Location82224850-82241280 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 82226192 bp
ZygosityHeterozygous
Amino Acid Change Phenylalanine to Tyrosine at position 198 (F198Y)
Ref Sequence ENSEMBL: ENSMUSP00000047110 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000041264] [ENSMUST00000156218]
Predicted Effect probably benign
Transcript: ENSMUST00000041264
AA Change: F198Y

PolyPhen 2 Score 0.332 (Sensitivity: 0.90; Specificity: 0.89)
SMART Domains Protein: ENSMUSP00000047110
Gene: ENSMUSG00000062931
AA Change: F198Y

DomainStartEndE-ValueType
KRAB 4 64 5.28e-14 SMART
ZnF_C2H2 161 188 2.82e1 SMART
ZnF_C2H2 267 289 1.23e0 SMART
ZnF_C2H2 295 317 2.91e-2 SMART
ZnF_C2H2 323 345 2.4e-3 SMART
ZnF_C2H2 351 373 7.26e-3 SMART
ZnF_C2H2 379 401 4.65e-1 SMART
ZnF_C2H2 407 429 1.47e-3 SMART
ZnF_C2H2 435 457 5.59e-4 SMART
ZnF_C2H2 463 485 1.82e-3 SMART
ZnF_C2H2 491 513 3.63e-3 SMART
ZnF_C2H2 519 541 7.67e-2 SMART
ZnF_C2H2 547 569 2.4e-3 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000156218
SMART Domains Protein: ENSMUSP00000121613
Gene: ENSMUSG00000062931

DomainStartEndE-ValueType
KRAB 4 64 5.28e-14 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 20 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930452B06Rik T C 14: 8,517,940 E293G probably benign Het
Avl9 C A 6: 56,736,873 T372N probably damaging Het
Ccni C T 5: 93,183,336 V135I probably benign Het
Dnah17 A G 11: 118,073,548 F2481S probably damaging Het
Dnajc10 A G 2: 80,331,303 D295G probably benign Het
Homer2 A G 7: 81,610,332 F265S probably damaging Het
Hsp90aa1 A G 12: 110,693,082 V476A probably benign Het
Jarid2 T C 13: 44,910,560 L855P probably damaging Het
Kif26a T A 12: 112,177,615 C1434* probably null Het
Lpo A G 11: 87,806,977 V668A possibly damaging Het
Med12l T C 3: 59,294,292 Y1973H probably damaging Het
Mep1b C A 18: 21,093,384 H434Q probably benign Het
Ngly1 T A 14: 16,290,939 probably benign Het
Ptprn A T 1: 75,262,363 F9L probably damaging Het
Sema6d T A 2: 124,664,073 N600K probably damaging Het
Slc1a1 C A 19: 28,905,338 A334E probably damaging Het
Son A G 16: 91,651,752 E67G probably damaging Het
Tpmt T C 13: 47,025,402 Y229C probably benign Het
Vmn2r23 A T 6: 123,741,619 I644F probably damaging Het
Whrn T C 4: 63,415,492 M906V probably benign Het
Other mutations in Zfp938
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00659:Zfp938 APN 10 82227521 utr 3 prime probably benign
IGL00743:Zfp938 APN 10 82226483 missense probably benign
IGL01764:Zfp938 APN 10 82227790 splice site probably benign
IGL01814:Zfp938 APN 10 82226218 missense probably benign
IGL02244:Zfp938 APN 10 82226072 missense possibly damaging 0.86
R0372:Zfp938 UTSW 10 82227828 missense probably damaging 1.00
R0666:Zfp938 UTSW 10 82225772 missense probably damaging 1.00
R0964:Zfp938 UTSW 10 82225419 missense probably benign 0.00
R1453:Zfp938 UTSW 10 82227798 critical splice donor site probably null
R1672:Zfp938 UTSW 10 82225148 missense probably benign
R1929:Zfp938 UTSW 10 82225547 missense probably damaging 1.00
R1959:Zfp938 UTSW 10 82225631 missense probably damaging 1.00
R2127:Zfp938 UTSW 10 82226042 missense probably benign
R2271:Zfp938 UTSW 10 82225547 missense probably damaging 1.00
R2900:Zfp938 UTSW 10 82225506 missense possibly damaging 0.92
R4502:Zfp938 UTSW 10 82226271 missense possibly damaging 0.73
R4503:Zfp938 UTSW 10 82226271 missense possibly damaging 0.73
R4886:Zfp938 UTSW 10 82226123 missense probably benign 0.33
R4934:Zfp938 UTSW 10 82226178 missense possibly damaging 0.86
R5174:Zfp938 UTSW 10 82226004 missense possibly damaging 0.53
R5410:Zfp938 UTSW 10 82225258 missense possibly damaging 0.89
R6284:Zfp938 UTSW 10 82227566 missense possibly damaging 0.73
R6491:Zfp938 UTSW 10 82227529 makesense probably null
R6575:Zfp938 UTSW 10 82225326 nonsense probably null
R6649:Zfp938 UTSW 10 82225398 missense probably damaging 0.99
X0066:Zfp938 UTSW 10 82226097 missense probably benign 0.33
Posted On2015-12-18