Incidental Mutation 'R0362:Nup205'
| ID |
36232 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nup205
|
| Ensembl Gene |
ENSMUSG00000038759 |
| Gene Name |
nucleoporin 205 |
| Synonyms |
3830404O05Rik |
| MMRRC Submission |
038568-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.963)
|
| Stock # |
R0362 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
35154551-35224534 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to A
at 35173649 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000144126
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043815]
[ENSMUST00000170234]
[ENSMUST00000201374]
|
| AlphaFold |
A0A0J9YUD5 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000043815
|
| SMART Domains |
Protein: ENSMUSP00000039656
Gene: ENSMUSG00000038759
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
13 |
N/A |
INTRINSIC |
|
Pfam:Nup192
|
14 |
1684 |
N/A |
PFAM |
|
low complexity region
|
1995 |
2005 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000170234
|
| SMART Domains |
Protein: ENSMUSP00000130033
Gene: ENSMUSG00000038759
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3414
|
13 |
322 |
9.7e-98 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000201374
|
| SMART Domains |
Protein: ENSMUSP00000144126
Gene: ENSMUSG00000038759
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
36 |
50 |
N/A |
INTRINSIC |
|
Pfam:Nup192
|
67 |
1737 |
N/A |
PFAM |
|
low complexity region
|
2048 |
2058 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202898
|
| Meta Mutation Damage Score |
0.9755 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.6%
- 10x: 96.8%
- 20x: 94.0%
|
| Validation Efficiency |
99% (104/105) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a nucleoporin, which is a subunit of the nuclear pore complex that functions in active transport of proteins, RNAs and ribonucleoprotein particles between the nucleus and cytoplasm. Mutations in this gene are associated with steroid-resistant nephrotic syndrome. [provided by RefSeq, Jul 2016]
|
| Allele List at MGI |
All alleles(32) : Targeted(2) Gene trapped(30)
|
| Other mutations in this stock |
Total: 103 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4932414N04Rik |
A |
G |
2: 68,563,261 (GRCm39) |
Q401R |
probably benign |
Het |
| Acp3 |
A |
G |
9: 104,191,626 (GRCm39) |
F220S |
probably damaging |
Het |
| Adam7 |
A |
G |
14: 68,747,105 (GRCm39) |
|
probably benign |
Het |
| Adamts6 |
A |
G |
13: 104,526,584 (GRCm39) |
|
probably null |
Het |
| Ascc3 |
T |
C |
10: 50,625,051 (GRCm39) |
|
probably benign |
Het |
| Atg10 |
T |
C |
13: 91,189,109 (GRCm39) |
|
probably null |
Het |
| Atm |
T |
C |
9: 53,370,138 (GRCm39) |
I2325V |
possibly damaging |
Het |
| Btnl9 |
C |
T |
11: 49,060,443 (GRCm39) |
R435H |
possibly damaging |
Het |
| Ccdc180 |
A |
G |
4: 45,923,551 (GRCm39) |
K1111E |
probably damaging |
Het |
| Ciao2b |
T |
C |
8: 105,368,222 (GRCm39) |
D34G |
probably null |
Het |
| Col11a2 |
T |
A |
17: 34,281,420 (GRCm39) |
|
probably null |
Het |
| Ctcfl |
A |
G |
2: 172,960,236 (GRCm39) |
W116R |
probably damaging |
Het |
| Ctsk |
A |
T |
3: 95,408,255 (GRCm39) |
Y37F |
probably damaging |
Het |
| Daam2 |
G |
C |
17: 49,787,813 (GRCm39) |
|
probably null |
Het |
| Dcdc2b |
T |
C |
4: 129,504,031 (GRCm39) |
|
probably null |
Het |
| Ddx28 |
C |
T |
8: 106,737,926 (GRCm39) |
R44Q |
probably damaging |
Het |
| Dhx29 |
T |
A |
13: 113,099,393 (GRCm39) |
N1139K |
probably benign |
Het |
| Dnah17 |
A |
T |
11: 117,989,365 (GRCm39) |
M1281K |
probably benign |
Het |
| Dnah6 |
T |
C |
6: 73,185,592 (GRCm39) |
S110G |
probably benign |
Het |
| Drc7 |
T |
C |
8: 95,799,483 (GRCm39) |
Y553H |
probably benign |
Het |
| Dync2h1 |
T |
C |
9: 7,005,487 (GRCm39) |
|
probably null |
Het |
| Ecm1 |
A |
G |
3: 95,644,369 (GRCm39) |
I152T |
possibly damaging |
Het |
| Edc4 |
C |
G |
8: 106,613,407 (GRCm39) |
P307R |
probably damaging |
Het |
| Eeig2 |
C |
T |
3: 108,887,497 (GRCm39) |
E256K |
probably benign |
Het |
| Egr1 |
A |
G |
18: 34,996,366 (GRCm39) |
T383A |
possibly damaging |
Het |
| Eml2 |
A |
G |
7: 18,924,731 (GRCm39) |
|
probably null |
Het |
| Eno4 |
A |
G |
19: 58,932,056 (GRCm39) |
|
probably benign |
Het |
| Erbb4 |
A |
T |
1: 68,369,429 (GRCm39) |
I404K |
probably damaging |
Het |
| Exoc7 |
G |
T |
11: 116,186,488 (GRCm39) |
T310K |
probably benign |
Het |
| Fam83e |
G |
T |
7: 45,376,393 (GRCm39) |
V369L |
probably benign |
Het |
| Fancc |
A |
T |
13: 63,545,970 (GRCm39) |
I91K |
possibly damaging |
Het |
| Fbn1 |
T |
C |
2: 125,151,697 (GRCm39) |
Q2519R |
probably damaging |
Het |
| Fhod3 |
T |
A |
18: 25,223,133 (GRCm39) |
C826* |
probably null |
Het |
| Foxi3 |
A |
G |
6: 70,933,612 (GRCm39) |
D33G |
probably benign |
Het |
| Gcn1 |
T |
C |
5: 115,714,167 (GRCm39) |
|
probably benign |
Het |
| Gm14221 |
T |
C |
2: 160,410,310 (GRCm39) |
|
noncoding transcript |
Het |
| Golga4 |
T |
A |
9: 118,384,853 (GRCm39) |
H630Q |
probably benign |
Het |
| Gpat4 |
T |
C |
8: 23,670,949 (GRCm39) |
S88G |
probably benign |
Het |
| Gucy2d |
A |
T |
7: 98,092,892 (GRCm39) |
S90C |
probably damaging |
Het |
| Has2 |
A |
C |
15: 56,545,057 (GRCm39) |
C182G |
probably damaging |
Het |
| Heatr5a |
A |
T |
12: 51,935,644 (GRCm39) |
S1647R |
probably damaging |
Het |
| Ifi35 |
T |
C |
11: 101,348,038 (GRCm39) |
V48A |
probably benign |
Het |
| Lig1 |
T |
A |
7: 13,030,730 (GRCm39) |
|
probably benign |
Het |
| Magi2 |
A |
G |
5: 19,432,573 (GRCm39) |
K96R |
probably damaging |
Het |
| Map7d1 |
G |
T |
4: 126,128,787 (GRCm39) |
P462Q |
probably damaging |
Het |
| Mdn1 |
A |
T |
4: 32,746,439 (GRCm39) |
|
probably null |
Het |
| Mfsd4a |
A |
T |
1: 131,987,013 (GRCm39) |
V105E |
probably damaging |
Het |
| Mrpl53 |
C |
T |
6: 83,086,526 (GRCm39) |
R77C |
probably damaging |
Het |
| Mtnr1b |
C |
T |
9: 15,785,600 (GRCm39) |
V53M |
probably damaging |
Het |
| Myo9b |
T |
C |
8: 71,800,414 (GRCm39) |
W990R |
probably damaging |
Het |
| Myt1 |
A |
T |
2: 181,405,186 (GRCm39) |
|
probably benign |
Het |
| Nf1 |
C |
T |
11: 79,427,704 (GRCm39) |
A1766V |
probably damaging |
Het |
| Nlrp3 |
T |
C |
11: 59,439,623 (GRCm39) |
V400A |
possibly damaging |
Het |
| Nxf1 |
T |
C |
19: 8,741,515 (GRCm39) |
|
probably null |
Het |
| Or7a36 |
A |
T |
10: 78,820,220 (GRCm39) |
M199L |
probably benign |
Het |
| P4hb |
T |
C |
11: 120,454,162 (GRCm39) |
K311E |
probably benign |
Het |
| Pafah1b1 |
T |
C |
11: 74,574,457 (GRCm39) |
N243S |
probably benign |
Het |
| Parp8 |
G |
A |
13: 117,061,504 (GRCm39) |
Q141* |
probably null |
Het |
| Pkd2l2 |
A |
C |
18: 34,568,380 (GRCm39) |
D543A |
probably benign |
Het |
| Pld5 |
A |
T |
1: 175,803,146 (GRCm39) |
L311* |
probably null |
Het |
| Plekha5 |
G |
A |
6: 140,537,473 (GRCm39) |
R646K |
possibly damaging |
Het |
| Plpp5 |
A |
T |
8: 26,214,219 (GRCm39) |
T144S |
probably benign |
Het |
| Ppp6r3 |
A |
G |
19: 3,528,285 (GRCm39) |
L542S |
probably damaging |
Het |
| Prkar2b |
A |
T |
12: 32,037,973 (GRCm39) |
|
probably null |
Het |
| Psmg1 |
A |
T |
16: 95,789,171 (GRCm39) |
S129T |
possibly damaging |
Het |
| Radil |
T |
C |
5: 142,529,582 (GRCm39) |
D38G |
probably benign |
Het |
| Ric1 |
T |
C |
19: 29,578,411 (GRCm39) |
|
probably null |
Het |
| Rp1l1 |
T |
A |
14: 64,268,515 (GRCm39) |
L1367* |
probably null |
Het |
| Rxfp1 |
A |
T |
3: 79,645,100 (GRCm39) |
M1K |
probably null |
Het |
| Serpina6 |
G |
T |
12: 103,618,208 (GRCm39) |
L202I |
probably damaging |
Het |
| Simc1 |
T |
C |
13: 54,676,280 (GRCm39) |
I98T |
probably damaging |
Het |
| Slc17a6 |
A |
G |
7: 51,308,519 (GRCm39) |
Y281C |
probably damaging |
Het |
| Slc26a11 |
T |
A |
11: 119,270,767 (GRCm39) |
|
probably benign |
Het |
| Slc34a1 |
T |
A |
13: 55,550,711 (GRCm39) |
|
probably null |
Het |
| Slfn10-ps |
T |
A |
11: 82,926,600 (GRCm39) |
|
noncoding transcript |
Het |
| Sohlh2 |
A |
G |
3: 55,115,163 (GRCm39) |
N383D |
probably damaging |
Het |
| Spag6 |
T |
A |
2: 18,715,302 (GRCm39) |
L27H |
probably damaging |
Het |
| Sptlc3 |
A |
G |
2: 139,388,475 (GRCm39) |
|
probably benign |
Het |
| St3gal4 |
T |
A |
9: 34,964,469 (GRCm39) |
K199* |
probably null |
Het |
| Stat5a |
T |
A |
11: 100,772,909 (GRCm39) |
D712E |
probably benign |
Het |
| Stmn2 |
A |
T |
3: 8,610,750 (GRCm39) |
D78V |
probably damaging |
Het |
| Stpg1 |
C |
T |
4: 135,233,777 (GRCm39) |
P20S |
possibly damaging |
Het |
| Taf2 |
A |
T |
15: 54,909,325 (GRCm39) |
V640E |
probably damaging |
Het |
| Tbce |
T |
C |
13: 14,172,747 (GRCm39) |
E501G |
probably benign |
Het |
| Tecpr2 |
A |
G |
12: 110,935,374 (GRCm39) |
S1398G |
probably damaging |
Het |
| Tenm4 |
T |
A |
7: 96,421,242 (GRCm39) |
Y598* |
probably null |
Het |
| Ticrr |
A |
G |
7: 79,327,088 (GRCm39) |
S599G |
probably damaging |
Het |
| Tnc |
A |
C |
4: 63,935,679 (GRCm39) |
V419G |
probably damaging |
Het |
| Trappc1 |
C |
A |
11: 69,216,402 (GRCm39) |
P110T |
probably benign |
Het |
| Trbv12-2 |
C |
T |
6: 41,095,993 (GRCm39) |
|
probably benign |
Het |
| Ttbk2 |
A |
T |
2: 120,576,264 (GRCm39) |
N835K |
possibly damaging |
Het |
| Tubgcp5 |
A |
G |
7: 55,450,432 (GRCm39) |
D181G |
probably damaging |
Het |
| Tut1 |
T |
C |
19: 8,932,891 (GRCm39) |
Y75H |
possibly damaging |
Het |
| Ulk2 |
C |
A |
11: 61,678,412 (GRCm39) |
C769F |
probably benign |
Het |
| Vdac1 |
T |
C |
11: 52,265,800 (GRCm39) |
|
probably benign |
Het |
| Vmn2r124 |
T |
C |
17: 18,284,486 (GRCm39) |
|
probably null |
Het |
| Vps8 |
T |
C |
16: 21,426,977 (GRCm39) |
|
probably benign |
Het |
| Wdr35 |
T |
C |
12: 9,045,625 (GRCm39) |
|
probably benign |
Het |
| Zdhhc7 |
T |
A |
8: 120,813,386 (GRCm39) |
E141V |
probably null |
Het |
| Zfp12 |
C |
A |
5: 143,230,978 (GRCm39) |
S435Y |
probably damaging |
Het |
| Zfp974 |
A |
T |
7: 27,626,819 (GRCm39) |
|
probably benign |
Het |
| Zfyve9 |
T |
A |
4: 108,538,166 (GRCm39) |
K1033N |
probably damaging |
Het |
| Zswim8 |
T |
A |
14: 20,772,013 (GRCm39) |
S1572T |
possibly damaging |
Het |
|
| Other mutations in Nup205 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00484:Nup205
|
APN |
6 |
35,191,737 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01086:Nup205
|
APN |
6 |
35,185,871 (GRCm39) |
splice site |
probably benign |
|
|
IGL01138:Nup205
|
APN |
6 |
35,185,019 (GRCm39) |
nonsense |
probably null |
|
|
IGL01333:Nup205
|
APN |
6 |
35,217,998 (GRCm39) |
missense |
probably benign |
|
|
IGL01399:Nup205
|
APN |
6 |
35,196,624 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL01466:Nup205
|
APN |
6 |
35,176,894 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01913:Nup205
|
APN |
6 |
35,204,365 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL02159:Nup205
|
APN |
6 |
35,166,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02442:Nup205
|
APN |
6 |
35,167,003 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02447:Nup205
|
APN |
6 |
35,204,511 (GRCm39) |
splice site |
probably null |
|
|
IGL02558:Nup205
|
APN |
6 |
35,166,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03306:Nup205
|
APN |
6 |
35,185,104 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03328:Nup205
|
APN |
6 |
35,209,349 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Figaro
|
UTSW |
6 |
35,173,649 (GRCm39) |
splice site |
probably null |
|
|
Marcellina
|
UTSW |
6 |
35,160,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Spirit
|
UTSW |
6 |
35,209,343 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Susanna
|
UTSW |
6 |
35,185,044 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
voyager
|
UTSW |
6 |
35,166,820 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
BB007:Nup205
|
UTSW |
6 |
35,171,511 (GRCm39) |
missense |
probably damaging |
0.98 |
|
BB017:Nup205
|
UTSW |
6 |
35,171,511 (GRCm39) |
missense |
probably damaging |
0.98 |
|
P0012:Nup205
|
UTSW |
6 |
35,173,478 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0102:Nup205
|
UTSW |
6 |
35,202,715 (GRCm39) |
splice site |
probably benign |
|
|
R0102:Nup205
|
UTSW |
6 |
35,202,715 (GRCm39) |
splice site |
probably benign |
|
|
R0374:Nup205
|
UTSW |
6 |
35,185,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0415:Nup205
|
UTSW |
6 |
35,191,569 (GRCm39) |
splice site |
probably benign |
|
|
R0427:Nup205
|
UTSW |
6 |
35,171,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0543:Nup205
|
UTSW |
6 |
35,175,904 (GRCm39) |
missense |
probably benign |
|
|
R0611:Nup205
|
UTSW |
6 |
35,202,903 (GRCm39) |
missense |
probably null |
1.00 |
|
R0761:Nup205
|
UTSW |
6 |
35,173,363 (GRCm39) |
splice site |
probably benign |
|
|
R0828:Nup205
|
UTSW |
6 |
35,171,501 (GRCm39) |
missense |
probably benign |
|
|
R0906:Nup205
|
UTSW |
6 |
35,213,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1023:Nup205
|
UTSW |
6 |
35,211,641 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1033:Nup205
|
UTSW |
6 |
35,204,377 (GRCm39) |
missense |
probably benign |
|
|
R1375:Nup205
|
UTSW |
6 |
35,177,006 (GRCm39) |
splice site |
probably benign |
|
|
R1447:Nup205
|
UTSW |
6 |
35,192,120 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1468:Nup205
|
UTSW |
6 |
35,202,917 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1468:Nup205
|
UTSW |
6 |
35,202,917 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1625:Nup205
|
UTSW |
6 |
35,168,878 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1652:Nup205
|
UTSW |
6 |
35,215,901 (GRCm39) |
missense |
probably benign |
|
|
R1659:Nup205
|
UTSW |
6 |
35,211,723 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1693:Nup205
|
UTSW |
6 |
35,187,906 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1769:Nup205
|
UTSW |
6 |
35,182,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1839:Nup205
|
UTSW |
6 |
35,196,649 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1959:Nup205
|
UTSW |
6 |
35,210,301 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2051:Nup205
|
UTSW |
6 |
35,207,451 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2267:Nup205
|
UTSW |
6 |
35,218,284 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R2401:Nup205
|
UTSW |
6 |
35,185,069 (GRCm39) |
nonsense |
probably null |
|
|
R3697:Nup205
|
UTSW |
6 |
35,165,646 (GRCm39) |
missense |
probably benign |
0.15 |
|
R3938:Nup205
|
UTSW |
6 |
35,196,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4074:Nup205
|
UTSW |
6 |
35,168,975 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4117:Nup205
|
UTSW |
6 |
35,217,947 (GRCm39) |
nonsense |
probably null |
|
|
R4364:Nup205
|
UTSW |
6 |
35,168,962 (GRCm39) |
missense |
probably benign |
0.38 |
|
R4366:Nup205
|
UTSW |
6 |
35,168,962 (GRCm39) |
missense |
probably benign |
0.38 |
|
R4594:Nup205
|
UTSW |
6 |
35,173,424 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4706:Nup205
|
UTSW |
6 |
35,178,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4787:Nup205
|
UTSW |
6 |
35,178,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4849:Nup205
|
UTSW |
6 |
35,207,505 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4850:Nup205
|
UTSW |
6 |
35,207,465 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4943:Nup205
|
UTSW |
6 |
35,201,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4966:Nup205
|
UTSW |
6 |
35,220,784 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5138:Nup205
|
UTSW |
6 |
35,202,801 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5251:Nup205
|
UTSW |
6 |
35,173,417 (GRCm39) |
splice site |
probably null |
|
|
R5444:Nup205
|
UTSW |
6 |
35,166,124 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5760:Nup205
|
UTSW |
6 |
35,224,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5762:Nup205
|
UTSW |
6 |
35,207,483 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5762:Nup205
|
UTSW |
6 |
35,204,615 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5941:Nup205
|
UTSW |
6 |
35,209,343 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5969:Nup205
|
UTSW |
6 |
35,154,513 (GRCm39) |
unclassified |
probably benign |
|
|
R6003:Nup205
|
UTSW |
6 |
35,189,751 (GRCm39) |
missense |
probably benign |
|
|
R6178:Nup205
|
UTSW |
6 |
35,220,778 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6315:Nup205
|
UTSW |
6 |
35,213,804 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6392:Nup205
|
UTSW |
6 |
35,166,820 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6710:Nup205
|
UTSW |
6 |
35,224,308 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6954:Nup205
|
UTSW |
6 |
35,185,044 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7022:Nup205
|
UTSW |
6 |
35,220,871 (GRCm39) |
missense |
probably benign |
0.45 |
|
R7041:Nup205
|
UTSW |
6 |
35,201,470 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R7052:Nup205
|
UTSW |
6 |
35,192,077 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7310:Nup205
|
UTSW |
6 |
35,202,904 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7363:Nup205
|
UTSW |
6 |
35,209,508 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7399:Nup205
|
UTSW |
6 |
35,191,611 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7428:Nup205
|
UTSW |
6 |
35,204,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7553:Nup205
|
UTSW |
6 |
35,178,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7665:Nup205
|
UTSW |
6 |
35,154,555 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7841:Nup205
|
UTSW |
6 |
35,224,372 (GRCm39) |
missense |
unknown |
|
|
R7930:Nup205
|
UTSW |
6 |
35,171,511 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7973:Nup205
|
UTSW |
6 |
35,222,274 (GRCm39) |
missense |
probably benign |
|
|
R7976:Nup205
|
UTSW |
6 |
35,175,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8073:Nup205
|
UTSW |
6 |
35,179,104 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8080:Nup205
|
UTSW |
6 |
35,204,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8118:Nup205
|
UTSW |
6 |
35,207,451 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8213:Nup205
|
UTSW |
6 |
35,202,138 (GRCm39) |
missense |
probably benign |
0.26 |
|
R8237:Nup205
|
UTSW |
6 |
35,204,438 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8408:Nup205
|
UTSW |
6 |
35,202,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8807:Nup205
|
UTSW |
6 |
35,160,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8812:Nup205
|
UTSW |
6 |
35,191,269 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9061:Nup205
|
UTSW |
6 |
35,196,808 (GRCm39) |
intron |
probably benign |
|
|
R9261:Nup205
|
UTSW |
6 |
35,176,792 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9403:Nup205
|
UTSW |
6 |
35,176,909 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9648:Nup205
|
UTSW |
6 |
35,202,746 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9744:Nup205
|
UTSW |
6 |
35,209,510 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9800:Nup205
|
UTSW |
6 |
35,163,468 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
Z1177:Nup205
|
UTSW |
6 |
35,185,728 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1177:Nup205
|
UTSW |
6 |
35,154,540 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GGACCTGGAACACTTAATGCTCCTG -3'
(R):5'- CCCAACTTGGTCAGCATCATGCATAC -3'
Sequencing Primer
(F):5'- GAACACTTAATGCTCCTGGTAAGTC -3'
(R):5'- GAGACCACAAGTGTTTCTGC -3'
|
| Posted On |
2013-05-09 |
Incidental Mutation