Incidental Mutation 'IGL02867:Ccdc125'
ID362383
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ccdc125
Ensembl Gene ENSMUSG00000048924
Gene Namecoiled-coil domain containing 125
Synonyms5830436D01Rik
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL02867
Quality Score
Status
Chromosome13
Chromosomal Location100669717-100697240 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to T at 100684282 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000130107 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000057325] [ENSMUST00000170347]
Predicted Effect probably benign
Transcript: ENSMUST00000057325
SMART Domains Protein: ENSMUSP00000058484
Gene: ENSMUSG00000048924

DomainStartEndE-ValueType
coiled coil region 101 193 N/A INTRINSIC
coiled coil region 286 308 N/A INTRINSIC
Blast:ETS 362 447 1e-35 BLAST
Predicted Effect probably benign
Transcript: ENSMUST00000170347
SMART Domains Protein: ENSMUSP00000130107
Gene: ENSMUSG00000048924

DomainStartEndE-ValueType
coiled coil region 101 151 N/A INTRINSIC
coiled coil region 260 282 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4932415D10Rik C T 10: 82,283,820 S482N probably damaging Het
Abcf2 T A 5: 24,571,151 Y310F probably benign Het
Adarb1 C T 10: 77,313,541 V371I probably benign Het
Antxr2 G T 5: 97,977,650 H249Q probably benign Het
Arel1 A T 12: 84,934,323 N303K probably benign Het
Bloc1s6 T C 2: 122,742,684 Y60H probably damaging Het
Cxcl16 A T 11: 70,459,066 Y45N possibly damaging Het
Dnajb3 T A 1: 88,205,527 Q51L probably benign Het
Ear10 A G 14: 43,923,269 F34L probably damaging Het
Fgf11 A G 11: 69,799,672 S100P possibly damaging Het
Fpgs G A 2: 32,685,879 probably benign Het
Fyb A T 15: 6,580,046 Q33H probably damaging Het
Ints3 G T 3: 90,392,836 H925N probably damaging Het
Krt16 T C 11: 100,247,576 K249E probably damaging Het
Lrp2 A T 2: 69,552,450 S30R possibly damaging Het
Naa35 T C 13: 59,608,854 probably benign Het
Olfr381 A G 11: 73,485,991 Y278H probably damaging Het
Olfr743 A G 14: 50,533,513 I34V probably benign Het
Olfr971 A G 9: 39,840,237 M268V probably benign Het
Osbpl6 A G 2: 76,595,870 probably benign Het
Pramel6 A T 2: 87,510,392 Q356L probably damaging Het
Prima1 A G 12: 103,197,316 V132A probably benign Het
Psme1 A G 14: 55,579,926 probably benign Het
Rdh11 A G 12: 79,189,054 V40A possibly damaging Het
Rin1 C T 19: 5,053,170 R485C probably damaging Het
Rnf40 C A 7: 127,591,429 S255* probably null Het
Spata24 C A 18: 35,656,752 R194L probably benign Het
Tas1r1 A T 4: 152,028,278 S773T probably damaging Het
Trdv5 G T 14: 54,148,972 probably benign Het
Trpc3 A C 3: 36,640,701 D701E probably benign Het
Vim A G 2: 13,580,680 R424G probably damaging Het
Vmn1r216 A C 13: 23,099,479 T111P probably damaging Het
Zbtb26 A C 2: 37,436,249 N247K probably benign Het
Zfp629 T G 7: 127,610,031 probably benign Het
Other mutations in Ccdc125
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01888:Ccdc125 APN 13 100687102 splice site probably benign
R0002:Ccdc125 UTSW 13 100693606 nonsense probably null
R0014:Ccdc125 UTSW 13 100684338 missense possibly damaging 0.82
R0717:Ccdc125 UTSW 13 100690358 missense probably damaging 0.99
R1661:Ccdc125 UTSW 13 100693573 missense probably benign 0.37
R1665:Ccdc125 UTSW 13 100693573 missense probably benign 0.37
R3118:Ccdc125 UTSW 13 100690319 missense possibly damaging 0.46
R3751:Ccdc125 UTSW 13 100677951 missense possibly damaging 0.90
R4415:Ccdc125 UTSW 13 100696309 missense possibly damaging 0.83
R4838:Ccdc125 UTSW 13 100677945 missense possibly damaging 0.52
R5734:Ccdc125 UTSW 13 100687114 missense possibly damaging 0.66
R5812:Ccdc125 UTSW 13 100684304 missense probably damaging 1.00
R6031:Ccdc125 UTSW 13 100684369 splice site probably null
R6031:Ccdc125 UTSW 13 100684369 splice site probably null
R6419:Ccdc125 UTSW 13 100690326 missense probably damaging 1.00
R6456:Ccdc125 UTSW 13 100696309 missense possibly damaging 0.83
R6733:Ccdc125 UTSW 13 100694487 missense probably benign 0.04
R7183:Ccdc125 UTSW 13 100690358 missense possibly damaging 0.90
R7354:Ccdc125 UTSW 13 100677874 splice site probably null
R7644:Ccdc125 UTSW 13 100678376 splice site probably null
R7910:Ccdc125 UTSW 13 100682819 missense possibly damaging 0.83
R7948:Ccdc125 UTSW 13 100696402 missense probably benign 0.00
R7973:Ccdc125 UTSW 13 100669823 start gained probably benign
X0027:Ccdc125 UTSW 13 100681845 missense probably damaging 1.00
Posted On2015-12-18