Incidental Mutation 'IGL02869:Rgs12'
| ID |
362422 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Rgs12
|
| Ensembl Gene |
ENSMUSG00000029101 |
| Gene Name |
regulator of G-protein signaling 12 |
| Synonyms |
4632412M04Rik, 1200016K18Rik |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.243)
|
| Stock # |
IGL02869
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
5 |
| Chromosomal Location |
35106789-35196988 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 35183227 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 310
(D310V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109924
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000030984]
[ENSMUST00000087684]
[ENSMUST00000114280]
[ENSMUST00000114281]
[ENSMUST00000114283]
[ENSMUST00000114284]
[ENSMUST00000114285]
[ENSMUST00000156339]
|
| AlphaFold |
Q8CGE9 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000030984
AA Change: D958V
PolyPhen 2
Score 0.781 (Sensitivity: 0.85; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000030984
Gene: ENSMUSG00000029101
AA Change: D958V
| Domain | Start | End | E-Value | Type |
|---|
|
PDZ
|
29 |
98 |
5.25e-18 |
SMART |
|
PTB
|
224 |
373 |
5.05e-28 |
SMART |
|
low complexity region
|
443 |
456 |
N/A |
INTRINSIC |
|
low complexity region
|
643 |
661 |
N/A |
INTRINSIC |
|
low complexity region
|
685 |
697 |
N/A |
INTRINSIC |
|
RGS
|
715 |
832 |
2.84e-41 |
SMART |
|
low complexity region
|
849 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
868 |
880 |
N/A |
INTRINSIC |
|
low complexity region
|
911 |
928 |
N/A |
INTRINSIC |
|
RBD
|
962 |
1032 |
3.12e-28 |
SMART |
|
RBD
|
1034 |
1104 |
2.44e-21 |
SMART |
|
GoLoco
|
1187 |
1209 |
9.74e-9 |
SMART |
|
low complexity region
|
1259 |
1280 |
N/A |
INTRINSIC |
|
low complexity region
|
1292 |
1308 |
N/A |
INTRINSIC |
|
low complexity region
|
1359 |
1378 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000087684
AA Change: D958V
PolyPhen 2
Score 0.966 (Sensitivity: 0.77; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000084970
Gene: ENSMUSG00000029101
AA Change: D958V
| Domain | Start | End | E-Value | Type |
|---|
|
PDZ
|
29 |
98 |
5.25e-18 |
SMART |
|
PTB
|
224 |
373 |
5.05e-28 |
SMART |
|
low complexity region
|
443 |
456 |
N/A |
INTRINSIC |
|
low complexity region
|
643 |
661 |
N/A |
INTRINSIC |
|
low complexity region
|
685 |
697 |
N/A |
INTRINSIC |
|
RGS
|
715 |
832 |
2.84e-41 |
SMART |
|
Pfam:RGS12_us1
|
836 |
953 |
4.3e-61 |
PFAM |
|
RBD
|
962 |
1032 |
3.12e-28 |
SMART |
|
RBD
|
1034 |
1104 |
2.44e-21 |
SMART |
|
Pfam:RGS12_us2
|
1106 |
1180 |
2.4e-37 |
PFAM |
|
GoLoco
|
1187 |
1209 |
9.74e-9 |
SMART |
|
Pfam:RGS12_usC
|
1238 |
1379 |
9.2e-49 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000114280
AA Change: D300V
PolyPhen 2
Score 0.658 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000109919
Gene: ENSMUSG00000029101
AA Change: D300V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
27 |
39 |
N/A |
INTRINSIC |
|
RGS
|
57 |
174 |
2.84e-41 |
SMART |
|
low complexity region
|
191 |
207 |
N/A |
INTRINSIC |
|
low complexity region
|
210 |
222 |
N/A |
INTRINSIC |
|
low complexity region
|
253 |
270 |
N/A |
INTRINSIC |
|
RBD
|
304 |
374 |
3.12e-28 |
SMART |
|
RBD
|
376 |
446 |
2.44e-21 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000114281
AA Change: D300V
PolyPhen 2
Score 0.889 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000109920
Gene: ENSMUSG00000029101
AA Change: D300V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
27 |
39 |
N/A |
INTRINSIC |
|
RGS
|
57 |
174 |
2.84e-41 |
SMART |
|
low complexity region
|
191 |
207 |
N/A |
INTRINSIC |
|
low complexity region
|
210 |
222 |
N/A |
INTRINSIC |
|
low complexity region
|
253 |
270 |
N/A |
INTRINSIC |
|
RBD
|
304 |
374 |
3.12e-28 |
SMART |
|
RBD
|
376 |
446 |
2.44e-21 |
SMART |
|
GoLoco
|
529 |
551 |
9.74e-9 |
SMART |
|
low complexity region
|
601 |
622 |
N/A |
INTRINSIC |
|
low complexity region
|
634 |
650 |
N/A |
INTRINSIC |
|
low complexity region
|
701 |
720 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000114283
AA Change: D300V
PolyPhen 2
Score 0.966 (Sensitivity: 0.77; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000109922
Gene: ENSMUSG00000029101
AA Change: D300V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
27 |
39 |
N/A |
INTRINSIC |
|
RGS
|
57 |
174 |
2.84e-41 |
SMART |
|
low complexity region
|
191 |
207 |
N/A |
INTRINSIC |
|
low complexity region
|
210 |
222 |
N/A |
INTRINSIC |
|
low complexity region
|
253 |
270 |
N/A |
INTRINSIC |
|
RBD
|
304 |
374 |
3.12e-28 |
SMART |
|
RBD
|
376 |
446 |
2.44e-21 |
SMART |
|
GoLoco
|
529 |
551 |
9.74e-9 |
SMART |
|
low complexity region
|
601 |
622 |
N/A |
INTRINSIC |
|
low complexity region
|
634 |
650 |
N/A |
INTRINSIC |
|
low complexity region
|
697 |
729 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000114284
AA Change: D310V
PolyPhen 2
Score 0.781 (Sensitivity: 0.85; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000109923
Gene: ENSMUSG00000029101
AA Change: D310V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
37 |
49 |
N/A |
INTRINSIC |
|
RGS
|
67 |
184 |
2.84e-41 |
SMART |
|
low complexity region
|
201 |
217 |
N/A |
INTRINSIC |
|
low complexity region
|
220 |
232 |
N/A |
INTRINSIC |
|
low complexity region
|
263 |
280 |
N/A |
INTRINSIC |
|
RBD
|
314 |
384 |
3.12e-28 |
SMART |
|
RBD
|
386 |
456 |
2.44e-21 |
SMART |
|
GoLoco
|
539 |
561 |
9.74e-9 |
SMART |
|
low complexity region
|
611 |
632 |
N/A |
INTRINSIC |
|
low complexity region
|
644 |
660 |
N/A |
INTRINSIC |
|
low complexity region
|
711 |
730 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000114285
AA Change: D310V
PolyPhen 2
Score 0.970 (Sensitivity: 0.77; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000109924
Gene: ENSMUSG00000029101
AA Change: D310V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
37 |
49 |
N/A |
INTRINSIC |
|
RGS
|
67 |
184 |
2.84e-41 |
SMART |
|
low complexity region
|
201 |
217 |
N/A |
INTRINSIC |
|
low complexity region
|
220 |
232 |
N/A |
INTRINSIC |
|
low complexity region
|
263 |
280 |
N/A |
INTRINSIC |
|
RBD
|
314 |
384 |
3.12e-28 |
SMART |
|
RBD
|
386 |
456 |
2.44e-21 |
SMART |
|
GoLoco
|
539 |
561 |
9.74e-9 |
SMART |
|
low complexity region
|
611 |
632 |
N/A |
INTRINSIC |
|
low complexity region
|
644 |
660 |
N/A |
INTRINSIC |
|
low complexity region
|
707 |
739 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000156819
AA Change: D16V
|
| SMART Domains |
Protein: ENSMUSP00000116913
Gene: ENSMUSG00000029101
AA Change: D16V
| Domain | Start | End | E-Value | Type |
|---|
|
RBD
|
21 |
91 |
3.12e-28 |
SMART |
|
RBD
|
93 |
163 |
2.44e-21 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141562
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000155162
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000175356
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135403
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000201936
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000150139
|
| SMART Domains |
Protein: ENSMUSP00000117158
Gene: ENSMUSG00000029101
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:RBD
|
2 |
33 |
5e-13 |
BLAST |
|
Pfam:RGS12_us2
|
35 |
80 |
5.8e-13 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000156339
|
| SMART Domains |
Protein: ENSMUSP00000115064
Gene: ENSMUSG00000029101
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RGS
|
1 |
30 |
1.3e-7 |
PFAM |
|
low complexity region
|
48 |
64 |
N/A |
INTRINSIC |
|
low complexity region
|
67 |
79 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930562C15Rik |
T |
A |
16: 4,685,323 (GRCm39) |
S1142T |
possibly damaging |
Het |
| Aadacl4fm5 |
T |
C |
4: 144,512,938 (GRCm39) |
I54V |
probably benign |
Het |
| Actr3b |
T |
G |
5: 26,037,433 (GRCm39) |
V215G |
probably damaging |
Het |
| Adam9 |
C |
T |
8: 25,460,634 (GRCm39) |
V617M |
probably damaging |
Het |
| Adgrl2 |
G |
T |
3: 148,596,241 (GRCm39) |
P32T |
probably damaging |
Het |
| Afg2a |
G |
T |
3: 37,518,694 (GRCm39) |
G743W |
probably damaging |
Het |
| Ago3 |
A |
T |
4: 126,261,580 (GRCm39) |
|
probably benign |
Het |
| Allc |
A |
C |
12: 28,623,206 (GRCm39) |
I20M |
probably benign |
Het |
| Asic3 |
G |
A |
5: 24,621,972 (GRCm39) |
W361* |
probably null |
Het |
| Atf7ip |
A |
G |
6: 136,583,577 (GRCm39) |
K1203E |
probably damaging |
Het |
| Babam2 |
C |
A |
5: 32,162,116 (GRCm39) |
H272Q |
possibly damaging |
Het |
| Baz2b |
G |
A |
2: 59,807,872 (GRCm39) |
T129I |
probably benign |
Het |
| C130073F10Rik |
A |
T |
4: 101,747,590 (GRCm39) |
Y146* |
probably null |
Het |
| Cd247 |
A |
G |
1: 165,684,986 (GRCm39) |
E74G |
probably damaging |
Het |
| Cdh17 |
A |
T |
4: 11,814,908 (GRCm39) |
Q778L |
probably benign |
Het |
| Ceacam1 |
T |
C |
7: 25,175,966 (GRCm39) |
D76G |
probably benign |
Het |
| Cela3a |
T |
C |
4: 137,131,145 (GRCm39) |
K198E |
probably benign |
Het |
| Cemip2 |
T |
A |
19: 21,789,241 (GRCm39) |
D558E |
probably damaging |
Het |
| Ces2a |
T |
A |
8: 105,465,691 (GRCm39) |
D281E |
probably damaging |
Het |
| Cetn2 |
A |
T |
X: 71,958,527 (GRCm39) |
D116E |
probably damaging |
Het |
| Cracd |
A |
G |
5: 77,006,890 (GRCm39) |
K1084E |
unknown |
Het |
| Ctu2 |
G |
T |
8: 123,205,530 (GRCm39) |
|
probably null |
Het |
| Cybb |
T |
C |
X: 9,308,828 (GRCm39) |
N469D |
probably benign |
Het |
| Cygb |
C |
T |
11: 116,540,749 (GRCm39) |
R79Q |
probably damaging |
Het |
| Cyp2d10 |
C |
T |
15: 82,288,069 (GRCm39) |
V186M |
possibly damaging |
Het |
| Defb29 |
T |
A |
2: 152,380,942 (GRCm39) |
|
probably null |
Het |
| Depdc7 |
T |
G |
2: 104,560,694 (GRCm39) |
Q100P |
probably damaging |
Het |
| Dhx30 |
A |
C |
9: 109,926,251 (GRCm39) |
I91R |
probably damaging |
Het |
| Dnm1l |
T |
A |
16: 16,159,288 (GRCm39) |
K105* |
probably null |
Het |
| Eddm13 |
T |
C |
7: 6,272,898 (GRCm39) |
|
probably benign |
Het |
| Efhc1 |
T |
C |
1: 21,037,567 (GRCm39) |
I248T |
probably damaging |
Het |
| Elapor1 |
A |
G |
3: 108,380,182 (GRCm39) |
I309T |
probably benign |
Het |
| Entpd2 |
A |
G |
2: 25,288,120 (GRCm39) |
T115A |
probably damaging |
Het |
| Epb42 |
G |
T |
2: 120,856,227 (GRCm39) |
A439E |
probably benign |
Het |
| Esm1 |
T |
G |
13: 113,346,618 (GRCm39) |
L81R |
probably damaging |
Het |
| F8 |
T |
C |
X: 74,330,987 (GRCm39) |
S968G |
probably benign |
Het |
| Fam234b |
T |
G |
6: 135,202,201 (GRCm39) |
Y308D |
probably damaging |
Het |
| Fbxo46 |
T |
G |
7: 18,871,139 (GRCm39) |
V586G |
probably damaging |
Het |
| Foxp1 |
C |
A |
6: 98,907,044 (GRCm39) |
|
probably benign |
Het |
| Gm10754 |
A |
T |
10: 97,518,136 (GRCm39) |
|
probably benign |
Het |
| Gm12695 |
A |
C |
4: 96,650,370 (GRCm39) |
|
probably benign |
Het |
| Gm5468 |
T |
C |
15: 25,414,726 (GRCm39) |
|
probably benign |
Het |
| Grhl1 |
T |
C |
12: 24,631,490 (GRCm39) |
S66P |
probably damaging |
Het |
| Gstt3 |
A |
T |
10: 75,612,576 (GRCm39) |
|
probably null |
Het |
| Gtf2i |
A |
G |
5: 134,308,281 (GRCm39) |
|
probably benign |
Het |
| Gzmk |
C |
A |
13: 113,308,560 (GRCm39) |
G175C |
probably damaging |
Het |
| Helz2 |
T |
C |
2: 180,872,939 (GRCm39) |
|
probably benign |
Het |
| Ift20 |
T |
C |
11: 78,430,780 (GRCm39) |
|
probably benign |
Het |
| Intu |
A |
G |
3: 40,642,216 (GRCm39) |
D491G |
probably damaging |
Het |
| Itch |
G |
T |
2: 155,015,853 (GRCm39) |
|
probably null |
Het |
| Itgb5 |
A |
G |
16: 33,665,362 (GRCm39) |
N26S |
possibly damaging |
Het |
| Lama2 |
A |
T |
10: 26,891,534 (GRCm39) |
S2526R |
probably damaging |
Het |
| Lat2 |
A |
G |
5: 134,637,027 (GRCm39) |
I40T |
probably damaging |
Het |
| Lipa |
T |
A |
19: 34,471,397 (GRCm39) |
M393L |
probably benign |
Het |
| Lipa |
G |
T |
19: 34,471,371 (GRCm39) |
|
probably benign |
Het |
| Lpcat1 |
T |
A |
13: 73,632,417 (GRCm39) |
L10H |
probably damaging |
Het |
| Lpcat3 |
T |
C |
6: 124,679,970 (GRCm39) |
Y348H |
possibly damaging |
Het |
| Lrp1b |
A |
T |
2: 40,591,842 (GRCm39) |
N50K |
unknown |
Het |
| Lrrk2 |
T |
A |
15: 91,634,480 (GRCm39) |
Y1415N |
probably damaging |
Het |
| Lsamp |
A |
T |
16: 41,965,078 (GRCm39) |
T312S |
probably benign |
Het |
| Man2a2 |
T |
C |
7: 80,013,689 (GRCm39) |
E454G |
probably benign |
Het |
| Mcm3 |
T |
C |
1: 20,879,063 (GRCm39) |
K570R |
probably damaging |
Het |
| Mctp2 |
C |
A |
7: 71,878,219 (GRCm39) |
|
probably null |
Het |
| Msantd2 |
T |
G |
9: 37,434,796 (GRCm39) |
C345W |
probably damaging |
Het |
| Musk |
T |
C |
4: 58,354,078 (GRCm39) |
I362T |
probably benign |
Het |
| Myh15 |
A |
T |
16: 48,965,767 (GRCm39) |
N1224I |
probably benign |
Het |
| Myo18a |
A |
G |
11: 77,755,612 (GRCm39) |
Y1983C |
probably damaging |
Het |
| Myo18a |
C |
T |
11: 77,720,699 (GRCm39) |
|
probably benign |
Het |
| Myrfl |
G |
T |
10: 116,664,909 (GRCm39) |
Q374K |
probably damaging |
Het |
| Ndrg1 |
T |
A |
15: 66,818,346 (GRCm39) |
Q87H |
probably benign |
Het |
| Nol9 |
G |
A |
4: 152,131,030 (GRCm39) |
C351Y |
probably damaging |
Het |
| Nr5a1 |
A |
G |
2: 38,598,141 (GRCm39) |
S219P |
probably benign |
Het |
| Or8b43 |
T |
C |
9: 38,360,489 (GRCm39) |
F107S |
possibly damaging |
Het |
| Or8g28 |
A |
T |
9: 39,169,520 (GRCm39) |
Y149* |
probably null |
Het |
| Pcdhb19 |
A |
G |
18: 37,631,690 (GRCm39) |
D495G |
probably damaging |
Het |
| Pfkm |
A |
G |
15: 98,026,123 (GRCm39) |
M573V |
probably damaging |
Het |
| Plec |
A |
T |
15: 76,065,516 (GRCm39) |
L1586Q |
probably damaging |
Het |
| Prelp |
C |
A |
1: 133,843,005 (GRCm39) |
E47* |
probably null |
Het |
| Rbm33 |
T |
A |
5: 28,615,753 (GRCm39) |
I32N |
probably damaging |
Het |
| Ripor2 |
A |
C |
13: 24,880,512 (GRCm39) |
H404P |
possibly damaging |
Het |
| Sh3d21 |
T |
C |
4: 126,056,034 (GRCm39) |
E124G |
probably benign |
Het |
| Shroom2 |
C |
T |
X: 151,442,549 (GRCm39) |
S872N |
probably benign |
Het |
| Slc44a5 |
A |
G |
3: 153,956,651 (GRCm39) |
Y301C |
probably damaging |
Het |
| Smap1 |
A |
T |
1: 23,930,995 (GRCm39) |
H66Q |
possibly damaging |
Het |
| Smyd1 |
G |
T |
6: 71,198,007 (GRCm39) |
|
probably benign |
Het |
| Sptbn4 |
T |
A |
7: 27,093,573 (GRCm39) |
|
probably benign |
Het |
| Srsf3-ps |
T |
A |
11: 98,516,146 (GRCm39) |
R76* |
probably null |
Het |
| Stag3 |
A |
G |
5: 138,280,955 (GRCm39) |
K49R |
probably damaging |
Het |
| Stim1 |
C |
A |
7: 101,917,758 (GRCm39) |
A46E |
unknown |
Het |
| Stxbp2 |
A |
T |
8: 3,691,971 (GRCm39) |
I538F |
probably benign |
Het |
| Tbc1d19 |
A |
G |
5: 53,992,559 (GRCm39) |
T114A |
probably benign |
Het |
| Tln2 |
G |
A |
9: 67,128,807 (GRCm39) |
|
probably benign |
Het |
| Trmt10a |
T |
A |
3: 137,857,945 (GRCm39) |
|
probably null |
Het |
| Vwde |
G |
A |
6: 13,187,136 (GRCm39) |
H784Y |
probably damaging |
Het |
| Zfp773 |
T |
C |
7: 7,137,232 (GRCm39) |
T121A |
probably benign |
Het |
|
| Other mutations in Rgs12 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01443:Rgs12
|
APN |
5 |
35,132,563 (GRCm39) |
missense |
probably benign |
0.25 |
|
IGL02296:Rgs12
|
APN |
5 |
35,123,464 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02337:Rgs12
|
APN |
5 |
35,177,697 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02483:Rgs12
|
APN |
5 |
35,187,861 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02989:Rgs12
|
APN |
5 |
35,122,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0015:Rgs12
|
UTSW |
5 |
35,180,120 (GRCm39) |
unclassified |
probably benign |
|
|
R0015:Rgs12
|
UTSW |
5 |
35,180,120 (GRCm39) |
unclassified |
probably benign |
|
|
R0046:Rgs12
|
UTSW |
5 |
35,122,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0046:Rgs12
|
UTSW |
5 |
35,122,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0106:Rgs12
|
UTSW |
5 |
35,124,008 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0106:Rgs12
|
UTSW |
5 |
35,124,008 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0233:Rgs12
|
UTSW |
5 |
35,187,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0233:Rgs12
|
UTSW |
5 |
35,187,842 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0245:Rgs12
|
UTSW |
5 |
35,187,424 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0611:Rgs12
|
UTSW |
5 |
35,176,804 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0704:Rgs12
|
UTSW |
5 |
35,180,466 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0723:Rgs12
|
UTSW |
5 |
35,181,710 (GRCm39) |
unclassified |
probably benign |
|
|
R1174:Rgs12
|
UTSW |
5 |
35,123,809 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1538:Rgs12
|
UTSW |
5 |
35,178,511 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1556:Rgs12
|
UTSW |
5 |
35,196,626 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R1774:Rgs12
|
UTSW |
5 |
35,123,747 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1791:Rgs12
|
UTSW |
5 |
35,123,456 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1866:Rgs12
|
UTSW |
5 |
35,123,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1872:Rgs12
|
UTSW |
5 |
35,123,165 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1923:Rgs12
|
UTSW |
5 |
35,189,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2012:Rgs12
|
UTSW |
5 |
35,187,872 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2107:Rgs12
|
UTSW |
5 |
35,124,079 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R3730:Rgs12
|
UTSW |
5 |
35,189,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3731:Rgs12
|
UTSW |
5 |
35,189,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3808:Rgs12
|
UTSW |
5 |
35,189,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3826:Rgs12
|
UTSW |
5 |
35,123,359 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3827:Rgs12
|
UTSW |
5 |
35,123,359 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3829:Rgs12
|
UTSW |
5 |
35,123,359 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3830:Rgs12
|
UTSW |
5 |
35,123,359 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4392:Rgs12
|
UTSW |
5 |
35,189,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4617:Rgs12
|
UTSW |
5 |
35,177,700 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5132:Rgs12
|
UTSW |
5 |
35,147,156 (GRCm39) |
intron |
probably benign |
|
|
R5213:Rgs12
|
UTSW |
5 |
35,122,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5296:Rgs12
|
UTSW |
5 |
35,178,448 (GRCm39) |
unclassified |
probably benign |
|
|
R5480:Rgs12
|
UTSW |
5 |
35,123,455 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5510:Rgs12
|
UTSW |
5 |
35,123,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5708:Rgs12
|
UTSW |
5 |
35,123,696 (GRCm39) |
missense |
probably benign |
0.41 |
|
R5987:Rgs12
|
UTSW |
5 |
35,177,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6053:Rgs12
|
UTSW |
5 |
35,123,296 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6113:Rgs12
|
UTSW |
5 |
35,177,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6401:Rgs12
|
UTSW |
5 |
35,177,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6736:Rgs12
|
UTSW |
5 |
35,180,436 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6807:Rgs12
|
UTSW |
5 |
35,180,515 (GRCm39) |
missense |
probably null |
0.27 |
|
R6857:Rgs12
|
UTSW |
5 |
35,187,366 (GRCm39) |
nonsense |
probably null |
|
|
R7082:Rgs12
|
UTSW |
5 |
35,124,050 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7250:Rgs12
|
UTSW |
5 |
35,122,841 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7276:Rgs12
|
UTSW |
5 |
35,183,715 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7444:Rgs12
|
UTSW |
5 |
35,183,287 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7632:Rgs12
|
UTSW |
5 |
35,122,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8049:Rgs12
|
UTSW |
5 |
35,183,374 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8089:Rgs12
|
UTSW |
5 |
35,177,692 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8241:Rgs12
|
UTSW |
5 |
35,123,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8797:Rgs12
|
UTSW |
5 |
35,186,915 (GRCm39) |
missense |
|
|
|
R8927:Rgs12
|
UTSW |
5 |
35,123,633 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8928:Rgs12
|
UTSW |
5 |
35,123,633 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9073:Rgs12
|
UTSW |
5 |
35,177,753 (GRCm39) |
unclassified |
probably benign |
|
|
R9211:Rgs12
|
UTSW |
5 |
35,123,165 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9485:Rgs12
|
UTSW |
5 |
35,189,614 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9550:Rgs12
|
UTSW |
5 |
35,196,665 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Rgs12
|
UTSW |
5 |
35,123,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Rgs12
|
UTSW |
5 |
35,183,696 (GRCm39) |
missense |
probably benign |
0.44 |
|
Z1177:Rgs12
|
UTSW |
5 |
35,122,198 (GRCm39) |
start gained |
probably benign |
|
|
| Posted On |
2015-12-18 |
Incidental Mutation