Incidental Mutation 'IGL02870:Vmn1r30'
| ID |
362524 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r30
|
| Ensembl Gene |
ENSMUSG00000095670 |
| Gene Name |
vomeronasal 1 receptor 30 |
| Synonyms |
V1rc22, V1rc9 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.072)
|
| Stock # |
IGL02870
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
6 |
| Chromosomal Location |
58411833-58420609 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 58412355 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 159
(V159A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000154098
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000078890]
[ENSMUST00000226334]
[ENSMUST00000227466]
[ENSMUST00000228577]
[ENSMUST00000228635]
|
| AlphaFold |
Q8R2D2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000078890
AA Change: V159A
PolyPhen 2
Score 0.013 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000087336
Gene: ENSMUSG00000095670
AA Change: V159A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:V1R
|
29 |
293 |
4.8e-53 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000203463
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000226334
AA Change: V159A
PolyPhen 2
Score 0.013 (Sensitivity: 0.96; Specificity: 0.78)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000227466
AA Change: V159A
PolyPhen 2
Score 0.013 (Sensitivity: 0.96; Specificity: 0.78)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228577
AA Change: V159A
PolyPhen 2
Score 0.013 (Sensitivity: 0.96; Specificity: 0.78)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228635
AA Change: V159A
PolyPhen 2
Score 0.013 (Sensitivity: 0.96; Specificity: 0.78)
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 41 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adgrv1 |
C |
T |
13: 81,711,851 (GRCm39) |
V1042M |
probably benign |
Het |
| Agmat |
C |
A |
4: 141,474,253 (GRCm39) |
H45N |
probably benign |
Het |
| Akap13 |
T |
A |
7: 75,258,936 (GRCm39) |
V520D |
probably damaging |
Het |
| Ccser1 |
T |
A |
6: 61,288,276 (GRCm39) |
N146K |
probably damaging |
Het |
| Cdhr4 |
T |
A |
9: 107,875,263 (GRCm39) |
|
probably null |
Het |
| Col4a1 |
G |
A |
8: 11,271,375 (GRCm39) |
T753I |
probably benign |
Het |
| Cyp3a59 |
T |
C |
5: 146,034,994 (GRCm39) |
I224T |
probably benign |
Het |
| Ddx19a |
G |
T |
8: 111,710,258 (GRCm39) |
P114Q |
probably damaging |
Het |
| Eftud2 |
A |
G |
11: 102,753,452 (GRCm39) |
V275A |
probably damaging |
Het |
| Fgd6 |
T |
C |
10: 93,881,026 (GRCm39) |
S627P |
probably damaging |
Het |
| Flywch1 |
C |
T |
17: 23,974,876 (GRCm39) |
G541D |
probably damaging |
Het |
| Grk2 |
T |
C |
19: 4,340,430 (GRCm39) |
D317G |
probably damaging |
Het |
| H2-M5 |
T |
C |
17: 37,299,925 (GRCm39) |
E83G |
probably benign |
Het |
| Hltf |
T |
C |
3: 20,154,037 (GRCm39) |
F658L |
probably damaging |
Het |
| Hmmr |
G |
T |
11: 40,604,902 (GRCm39) |
Q390K |
possibly damaging |
Het |
| Lama1 |
G |
A |
17: 68,111,531 (GRCm39) |
G2261R |
probably damaging |
Het |
| Nsd1 |
A |
T |
13: 55,461,416 (GRCm39) |
T2548S |
probably benign |
Het |
| Or1j13 |
G |
A |
2: 36,370,043 (GRCm39) |
A33V |
probably benign |
Het |
| P3h1 |
C |
T |
4: 119,104,768 (GRCm39) |
R684W |
probably damaging |
Het |
| Peli2 |
G |
A |
14: 48,493,722 (GRCm39) |
V315M |
probably damaging |
Het |
| Pfkl |
T |
A |
10: 77,836,673 (GRCm39) |
K115* |
probably null |
Het |
| Plcxd1 |
A |
G |
5: 110,249,271 (GRCm39) |
T33A |
probably damaging |
Het |
| Ranbp17 |
A |
G |
11: 33,193,262 (GRCm39) |
S931P |
probably damaging |
Het |
| Retsat |
T |
C |
6: 72,584,007 (GRCm39) |
Y500H |
probably damaging |
Het |
| Rfx8 |
C |
T |
1: 39,722,871 (GRCm39) |
V249I |
possibly damaging |
Het |
| Runx1t1 |
A |
T |
4: 13,889,867 (GRCm39) |
I599L |
unknown |
Het |
| Sardh |
A |
T |
2: 27,125,503 (GRCm39) |
I337N |
possibly damaging |
Het |
| Serpinb7 |
A |
T |
1: 107,378,017 (GRCm39) |
M237L |
probably damaging |
Het |
| Slc35f1 |
A |
G |
10: 52,809,303 (GRCm39) |
S97G |
possibly damaging |
Het |
| Stab1 |
T |
C |
14: 30,861,354 (GRCm39) |
D2520G |
probably benign |
Het |
| Tnfrsf11b |
C |
T |
15: 54,119,423 (GRCm39) |
V184M |
probably benign |
Het |
| Trpv4 |
A |
T |
5: 114,763,117 (GRCm39) |
V764E |
probably damaging |
Het |
| Tsc22d1 |
C |
A |
14: 76,655,057 (GRCm39) |
A430E |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,580,949 (GRCm39) |
R23315G |
probably damaging |
Het |
| Txnrd1 |
A |
G |
10: 82,731,813 (GRCm39) |
I478M |
probably benign |
Het |
| Ush2a |
T |
C |
1: 188,410,555 (GRCm39) |
V2401A |
probably benign |
Het |
| Vill |
T |
C |
9: 118,890,967 (GRCm39) |
L191P |
probably damaging |
Het |
| Washc4 |
T |
A |
10: 83,421,740 (GRCm39) |
N939K |
probably benign |
Het |
| Wdfy3 |
A |
G |
5: 102,003,337 (GRCm39) |
V2926A |
probably damaging |
Het |
| Wdr7 |
T |
C |
18: 63,924,914 (GRCm39) |
S966P |
probably benign |
Het |
| Zfp12 |
C |
A |
5: 143,231,086 (GRCm39) |
T471N |
probably damaging |
Het |
|
| Other mutations in Vmn1r30 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01657:Vmn1r30
|
APN |
6 |
58,412,619 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02432:Vmn1r30
|
APN |
6 |
58,412,655 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02627:Vmn1r30
|
APN |
6 |
58,412,746 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0360:Vmn1r30
|
UTSW |
6 |
58,412,262 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1071:Vmn1r30
|
UTSW |
6 |
58,412,813 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1335:Vmn1r30
|
UTSW |
6 |
58,412,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1888:Vmn1r30
|
UTSW |
6 |
58,412,475 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1888:Vmn1r30
|
UTSW |
6 |
58,412,475 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2483:Vmn1r30
|
UTSW |
6 |
58,412,437 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3622:Vmn1r30
|
UTSW |
6 |
58,412,437 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3623:Vmn1r30
|
UTSW |
6 |
58,412,437 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3624:Vmn1r30
|
UTSW |
6 |
58,412,437 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3744:Vmn1r30
|
UTSW |
6 |
58,412,804 (GRCm39) |
nonsense |
probably null |
|
|
R3762:Vmn1r30
|
UTSW |
6 |
58,412,278 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4483:Vmn1r30
|
UTSW |
6 |
58,412,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4484:Vmn1r30
|
UTSW |
6 |
58,412,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5160:Vmn1r30
|
UTSW |
6 |
58,412,368 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5408:Vmn1r30
|
UTSW |
6 |
58,412,029 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5461:Vmn1r30
|
UTSW |
6 |
58,412,759 (GRCm39) |
nonsense |
probably null |
|
|
R5888:Vmn1r30
|
UTSW |
6 |
58,412,550 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7068:Vmn1r30
|
UTSW |
6 |
58,411,995 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7490:Vmn1r30
|
UTSW |
6 |
58,412,214 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7680:Vmn1r30
|
UTSW |
6 |
58,412,284 (GRCm39) |
nonsense |
probably null |
|
|
R7751:Vmn1r30
|
UTSW |
6 |
58,412,397 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8516:Vmn1r30
|
UTSW |
6 |
58,412,109 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8728:Vmn1r30
|
UTSW |
6 |
58,412,460 (GRCm39) |
missense |
probably benign |
|
|
R9351:Vmn1r30
|
UTSW |
6 |
58,412,262 (GRCm39) |
missense |
probably benign |
0.03 |
|
| Posted On |
2015-12-18 |
Incidental Mutation