Incidental Mutation 'IGL02883:Vmn1r128'
ID362860
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r128
Ensembl Gene ENSMUSG00000095758
Gene Namevomeronasal 1 receptor 128
SynonymsGm8509
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL02883
Quality Score
Status
Chromosome7
Chromosomal Location21349373-21350296 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 21349515 bp
ZygosityHeterozygous
Amino Acid Change Lysine to Arginine at position 48 (K48R)
Ref Sequence ENSEMBL: ENSMUSP00000129433 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000169165]
Predicted Effect probably benign
Transcript: ENSMUST00000169165
AA Change: K48R

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
SMART Domains Protein: ENSMUSP00000129433
Gene: ENSMUSG00000095758
AA Change: K48R

DomainStartEndE-ValueType
Pfam:TAS2R 8 299 3.6e-16 PFAM
Pfam:7tm_1 31 288 3.8e-6 PFAM
Pfam:V1R 41 296 8.4e-15 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1810055G02Rik C A 19: 3,716,972 S186R possibly damaging Het
Acap2 A G 16: 31,096,345 probably benign Het
Cacna1h G T 17: 25,380,532 R1726S probably damaging Het
Cdca2 T C 14: 67,707,497 S133G probably damaging Het
Cep295nl A T 11: 118,333,909 S36R probably benign Het
Crispld1 A G 1: 17,746,789 N190S possibly damaging Het
Crtam A G 9: 40,994,501 V44A probably benign Het
Crtc1 C T 8: 70,406,125 G112S probably benign Het
Cyp17a1 T C 19: 46,669,351 N254S probably benign Het
Dmrta1 T C 4: 89,688,774 S156P probably benign Het
Eno2 A C 6: 124,766,209 V188G probably damaging Het
Fam20a A T 11: 109,675,127 I427N probably damaging Het
Fat2 T C 11: 55,256,618 K3933E probably benign Het
Gm15448 A G 7: 3,822,180 S488P possibly damaging Het
Igkv8-30 T C 6: 70,117,617 M1V probably null Het
Ist1 G A 8: 109,683,668 probably benign Het
Kank4 T C 4: 98,773,453 E765G possibly damaging Het
Kat14 T C 2: 144,393,529 L92S probably damaging Het
Kcnu1 G A 8: 25,849,827 V58I probably benign Het
Lrba T A 3: 86,445,413 I1956N probably damaging Het
Lrba T A 3: 86,354,206 V1489E probably damaging Het
Mdn1 G A 4: 32,763,199 V5100I probably benign Het
Mkrn2os C A 6: 115,586,709 G122* probably null Het
Nme3 T C 17: 24,896,906 Y78H probably benign Het
Pkd1l2 G A 8: 117,065,745 T436I probably benign Het
Ppp2r5c T G 12: 110,522,563 V56G possibly damaging Het
Pramef25 T C 4: 143,949,848 T229A possibly damaging Het
Prdm10 G A 9: 31,327,348 V179M probably damaging Het
Rab11fip2 A G 19: 59,906,998 V344A probably damaging Het
Selp G A 1: 164,130,102 A267T probably benign Het
Sf3a1 T A 11: 4,179,192 W718R probably damaging Het
Taar9 T C 10: 24,109,480 N19D probably benign Het
Tas2r113 T G 6: 132,893,419 S137A probably damaging Het
Traf4 A T 11: 78,161,621 I66N possibly damaging Het
Ucp3 A T 7: 100,480,642 T164S probably benign Het
Uggt1 A T 1: 36,177,615 N96K probably benign Het
Uqcc1 T A 2: 155,911,829 Q42L possibly damaging Het
Other mutations in Vmn1r128
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00972:Vmn1r128 APN 7 21350076 missense probably benign 0.01
IGL02169:Vmn1r128 APN 7 21350238 missense probably damaging 0.99
R1740:Vmn1r128 UTSW 7 21349944 missense probably benign 0.00
R2969:Vmn1r128 UTSW 7 21350121 missense probably damaging 1.00
R4583:Vmn1r128 UTSW 7 21349719 missense possibly damaging 0.79
R4867:Vmn1r128 UTSW 7 21350014 missense possibly damaging 0.53
R5266:Vmn1r128 UTSW 7 21349403 missense probably benign 0.14
R5631:Vmn1r128 UTSW 7 21349375 start codon destroyed probably null 1.00
R6267:Vmn1r128 UTSW 7 21350296 makesense probably null
R7376:Vmn1r128 UTSW 7 21349743 missense probably damaging 1.00
Posted On2015-12-18