Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02883:Vmn1r128'

362860

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r128

Ensembl Gene

ENSMUSG00000095758

Gene Name

vomeronasal 1 receptor 128

Synonyms

Gm8509

Accession Numbers

Is this an essential gene?

Not available question?

Stock #

IGL02883

Quality Score

Status

Chromosome

Chromosomal Location

21349373-21350296 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 21349515 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Arginine at position 48 (K48R)

Ref Sequence

ENSEMBL: ENSMUSP00000129433 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000169165]

AlphaFold

L7N2B4

Predicted Effect

probably benign
Transcript: ENSMUST00000169165
AA Change: K48R

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000129433
Gene: ENSMUSG00000095758
AA Change: K48R

Domain	Start	End	E-Value	Type
Pfam:TAS2R	8	299	3.6e-16	PFAM
Pfam:7tm_1	31	288	3.8e-6	PFAM
Pfam:V1R	41	296	8.4e-15	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 37 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1810055G02Rik	C	A	19: 3,716,972	S186R	possibly damaging	Het
Acap2	A	G	16: 31,096,345		probably benign	Het
Cacna1h	G	T	17: 25,380,532	R1726S	probably damaging	Het
Cdca2	T	C	14: 67,707,497	S133G	probably damaging	Het
Cep295nl	A	T	11: 118,333,909	S36R	probably benign	Het
Crispld1	A	G	1: 17,746,789	N190S	possibly damaging	Het
Crtam	A	G	9: 40,994,501	V44A	probably benign	Het
Crtc1	C	T	8: 70,406,125	G112S	probably benign	Het
Cyp17a1	T	C	19: 46,669,351	N254S	probably benign	Het
Dmrta1	T	C	4: 89,688,774	S156P	probably benign	Het
Eno2	A	C	6: 124,766,209	V188G	probably damaging	Het
Fam20a	A	T	11: 109,675,127	I427N	probably damaging	Het
Fat2	T	C	11: 55,256,618	K3933E	probably benign	Het
Gm15448	A	G	7: 3,822,180	S488P	possibly damaging	Het
Igkv8-30	T	C	6: 70,117,617	M1V	probably null	Het
Ist1	G	A	8: 109,683,668		probably benign	Het
Kank4	T	C	4: 98,773,453	E765G	possibly damaging	Het
Kat14	T	C	2: 144,393,529	L92S	probably damaging	Het
Kcnu1	G	A	8: 25,849,827	V58I	probably benign	Het
Lrba	T	A	3: 86,445,413	I1956N	probably damaging	Het
Lrba	T	A	3: 86,354,206	V1489E	probably damaging	Het
Mdn1	G	A	4: 32,763,199	V5100I	probably benign	Het
Mkrn2os	C	A	6: 115,586,709	G122*	probably null	Het
Nme3	T	C	17: 24,896,906	Y78H	probably benign	Het
Pkd1l2	G	A	8: 117,065,745	T436I	probably benign	Het
Ppp2r5c	T	G	12: 110,522,563	V56G	possibly damaging	Het
Pramef25	T	C	4: 143,949,848	T229A	possibly damaging	Het
Prdm10	G	A	9: 31,327,348	V179M	probably damaging	Het
Rab11fip2	A	G	19: 59,906,998	V344A	probably damaging	Het
Selp	G	A	1: 164,130,102	A267T	probably benign	Het
Sf3a1	T	A	11: 4,179,192	W718R	probably damaging	Het
Taar9	T	C	10: 24,109,480	N19D	probably benign	Het
Tas2r113	T	G	6: 132,893,419	S137A	probably damaging	Het
Traf4	A	T	11: 78,161,621	I66N	possibly damaging	Het
Ucp3	A	T	7: 100,480,642	T164S	probably benign	Het
Uggt1	A	T	1: 36,177,615	N96K	probably benign	Het
Uqcc1	T	A	2: 155,911,829	Q42L	possibly damaging	Het

Other mutations in Vmn1r128

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00972:Vmn1r128	APN	7	21350076	missense	probably benign	0.01
IGL02169:Vmn1r128	APN	7	21350238	missense	probably damaging	0.99
R1740:Vmn1r128	UTSW	7	21349944	missense	probably benign	0.00
R2969:Vmn1r128	UTSW	7	21350121	missense	probably damaging	1.00
R4583:Vmn1r128	UTSW	7	21349719	missense	possibly damaging	0.79
R4867:Vmn1r128	UTSW	7	21350014	missense	possibly damaging	0.53
R5266:Vmn1r128	UTSW	7	21349403	missense	probably benign	0.14
R5631:Vmn1r128	UTSW	7	21349375	start codon destroyed	probably null	1.00
R6267:Vmn1r128	UTSW	7	21350296	makesense	probably null
R7376:Vmn1r128	UTSW	7	21349743	missense	probably damaging	1.00
R8351:Vmn1r128	UTSW	7	21349672	missense	probably damaging	1.00
R8440:Vmn1r128	UTSW	7	21349820	missense	probably benign	0.22
R8773:Vmn1r128	UTSW	7	21349997	missense	probably benign	0.41
R8889:Vmn1r128	UTSW	7	21349815	missense	possibly damaging	0.61
R9182:Vmn1r128	UTSW	7	21349758	missense	possibly damaging	0.72
R9200:Vmn1r128	UTSW	7	21349391	missense	possibly damaging	0.89

Posted On

2015-12-18