Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02883:Lrba'

362886

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Lrba

Ensembl Gene

ENSMUSG00000028080

Gene Name

LPS-responsive beige-like anchor

Synonyms

Lba, D3Ertd775e

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02883

Quality Score

Status

Chromosome

Chromosomal Location

86224680-86782692 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 86445413 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Asparagine at position 1956 (I1956N)

Ref Sequence

ENSEMBL: ENSMUSP00000142179 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000107635] [ENSMUST00000192145] [ENSMUST00000194759] [ENSMUST00000212390]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000107635
AA Change: I1956N

PolyPhen 2 Score 0.979 (Sensitivity: 0.75; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000103261
Gene: ENSMUSG00000028080
AA Change: I1956N

Domain	Start	End	E-Value	Type
low complexity region	12	31	N/A	INTRINSIC
Pfam:Laminin_G_3	211	377	4.6e-13	PFAM
Pfam:DUF4704	446	717	2.5e-109	PFAM
coiled coil region	1019	1037	N/A	INTRINSIC
low complexity region	1073	1089	N/A	INTRINSIC
low complexity region	1100	1113	N/A	INTRINSIC
low complexity region	1585	1600	N/A	INTRINSIC
low complexity region	1614	1630	N/A	INTRINSIC
low complexity region	1698	1713	N/A	INTRINSIC
low complexity region	1738	1757	N/A	INTRINSIC
low complexity region	1848	1861	N/A	INTRINSIC
Pfam:DUF1088	1882	2049	7e-88	PFAM
Pfam:PH_BEACH	2075	2172	9.1e-31	PFAM
Beach	2203	2480	2.87e-207	SMART
WD40	2578	2615	7.4e0	SMART
WD40	2618	2661	1.72e0	SMART
WD40	2677	2716	3.99e-1	SMART
WD40	2760	2798	1.79e-1	SMART
WD40	2801	2840	4.28e0	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000192145
AA Change: I1956N

PolyPhen 2 Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000142179
Gene: ENSMUSG00000028080
AA Change: I1956N

Domain	Start	End	E-Value	Type
low complexity region	12	31	N/A	INTRINSIC
Pfam:Laminin_G_3	205	377	7.4e-18	PFAM
coiled coil region	1019	1037	N/A	INTRINSIC
low complexity region	1073	1089	N/A	INTRINSIC
low complexity region	1100	1113	N/A	INTRINSIC
low complexity region	1585	1600	N/A	INTRINSIC
low complexity region	1614	1630	N/A	INTRINSIC
low complexity region	1698	1713	N/A	INTRINSIC
low complexity region	1738	1757	N/A	INTRINSIC
low complexity region	1848	1861	N/A	INTRINSIC
Pfam:DUF1088	1882	2050	1.5e-92	PFAM
Pfam:PH_BEACH	2068	2172	7.5e-32	PFAM
Beach	2203	2480	2.87e-207	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000194759
AA Change: I1956N

PolyPhen 2 Score 0.017 (Sensitivity: 0.95; Specificity: 0.80)

SMART Domains

Protein: ENSMUSP00000142043
Gene: ENSMUSG00000028080
AA Change: I1956N

Domain	Start	End	E-Value	Type
low complexity region	12	31	N/A	INTRINSIC
Pfam:Laminin_G_3	205	377	8.1e-18	PFAM
coiled coil region	1019	1037	N/A	INTRINSIC
low complexity region	1073	1089	N/A	INTRINSIC
low complexity region	1100	1113	N/A	INTRINSIC
low complexity region	1585	1600	N/A	INTRINSIC
low complexity region	1614	1630	N/A	INTRINSIC
low complexity region	1698	1713	N/A	INTRINSIC
low complexity region	1738	1757	N/A	INTRINSIC
low complexity region	1848	1861	N/A	INTRINSIC
Pfam:DUF1088	1882	2050	1.6e-92	PFAM
Pfam:PH_BEACH	2068	2172	8.3e-32	PFAM
Beach	2203	2480	2.87e-207	SMART
WD40	2578	2615	7.4e0	SMART
WD40	2618	2661	1.72e0	SMART
WD40	2677	2716	3.99e-1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000212390
AA Change: I1956N

PolyPhen 2 Score 0.072 (Sensitivity: 0.94; Specificity: 0.84)

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased numbers of myeloid-derived suppressor cells and regulatory T cells, abnormal NK cell physiology, impaired rejection of allogeneic, xenogeneic and missing self bone-marrow grafts, and resistance to acute graft vs host disease. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 36 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1810055G02Rik	C	A	19: 3,716,972 (GRCm38)	S186R	possibly damaging	Het
Acap2	A	G	16: 31,096,345 (GRCm38)		probably benign	Het
Cacna1h	G	T	17: 25,380,532 (GRCm38)	R1726S	probably damaging	Het
Cdca2	T	C	14: 67,707,497 (GRCm38)	S133G	probably damaging	Het
Cep295nl	A	T	11: 118,333,909 (GRCm38)	S36R	probably benign	Het
Crispld1	A	G	1: 17,746,789 (GRCm38)	N190S	possibly damaging	Het
Crtam	A	G	9: 40,994,501 (GRCm38)	V44A	probably benign	Het
Crtc1	C	T	8: 70,406,125 (GRCm38)	G112S	probably benign	Het
Cyp17a1	T	C	19: 46,669,351 (GRCm38)	N254S	probably benign	Het
Dmrta1	T	C	4: 89,688,774 (GRCm38)	S156P	probably benign	Het
Eno2	A	C	6: 124,766,209 (GRCm38)	V188G	probably damaging	Het
Fam20a	A	T	11: 109,675,127 (GRCm38)	I427N	probably damaging	Het
Fat2	T	C	11: 55,256,618 (GRCm38)	K3933E	probably benign	Het
Gm15448	A	G	7: 3,822,180 (GRCm38)	S488P	possibly damaging	Het
Igkv8-30	T	C	6: 70,117,617 (GRCm38)	M1V	probably null	Het
Ist1	G	A	8: 109,683,668 (GRCm38)		probably benign	Het
Kank4	T	C	4: 98,773,453 (GRCm38)	E765G	possibly damaging	Het
Kat14	T	C	2: 144,393,529 (GRCm38)	L92S	probably damaging	Het
Kcnu1	G	A	8: 25,849,827 (GRCm38)	V58I	probably benign	Het
Mdn1	G	A	4: 32,763,199 (GRCm38)	V5100I	probably benign	Het
Mkrn2os	C	A	6: 115,586,709 (GRCm38)	G122*	probably null	Het
Nme3	T	C	17: 24,896,906 (GRCm38)	Y78H	probably benign	Het
Pkd1l2	G	A	8: 117,065,745 (GRCm38)	T436I	probably benign	Het
Ppp2r5c	T	G	12: 110,522,563 (GRCm38)	V56G	possibly damaging	Het
Pramef25	T	C	4: 143,949,848 (GRCm38)	T229A	possibly damaging	Het
Prdm10	G	A	9: 31,327,348 (GRCm38)	V179M	probably damaging	Het
Rab11fip2	A	G	19: 59,906,998 (GRCm38)	V344A	probably damaging	Het
Selp	G	A	1: 164,130,102 (GRCm38)	A267T	probably benign	Het
Sf3a1	T	A	11: 4,179,192 (GRCm38)	W718R	probably damaging	Het
Taar9	T	C	10: 24,109,480 (GRCm38)	N19D	probably benign	Het
Tas2r113	T	G	6: 132,893,419 (GRCm38)	S137A	probably damaging	Het
Traf4	A	T	11: 78,161,621 (GRCm38)	I66N	possibly damaging	Het
Ucp3	A	T	7: 100,480,642 (GRCm38)	T164S	probably benign	Het
Uggt1	A	T	1: 36,177,615 (GRCm38)	N96K	probably benign	Het
Uqcc1	T	A	2: 155,911,829 (GRCm38)	Q42L	possibly damaging	Het
Vmn1r128	A	G	7: 21,349,515 (GRCm38)	K48R	probably benign	Het

Other mutations in Lrba

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00420:Lrba	APN	3	86,359,782 (GRCm38)	missense	probably benign	0.00
IGL00788:Lrba	APN	3	86,327,685 (GRCm38)	missense	probably damaging	0.97
IGL01139:Lrba	APN	3	86,642,662 (GRCm38)	missense	possibly damaging	0.88
IGL01302:Lrba	APN	3	86,295,400 (GRCm38)	missense	probably damaging	1.00
IGL01612:Lrba	APN	3	86,776,177 (GRCm38)	missense	possibly damaging	0.89
IGL01718:Lrba	APN	3	86,351,248 (GRCm38)	missense	probably damaging	1.00
IGL01719:Lrba	APN	3	86,327,596 (GRCm38)	splice site	probably benign
IGL01730:Lrba	APN	3	86,741,424 (GRCm38)	missense	possibly damaging	0.89
IGL01735:Lrba	APN	3	86,327,661 (GRCm38)	missense	probably benign	0.28
IGL01875:Lrba	APN	3	86,310,047 (GRCm38)	missense	probably damaging	1.00
IGL01884:Lrba	APN	3	86,310,412 (GRCm38)	missense	possibly damaging	0.86
IGL02264:Lrba	APN	3	86,780,262 (GRCm38)	missense	probably damaging	0.99
IGL02638:Lrba	APN	3	86,325,073 (GRCm38)	missense	probably damaging	0.97
IGL02647:Lrba	APN	3	86,359,731 (GRCm38)	missense	probably benign	0.00
IGL02664:Lrba	APN	3	86,325,731 (GRCm38)	missense	possibly damaging	0.84
IGL02728:Lrba	APN	3	86,776,049 (GRCm38)	missense	probably damaging	0.99
IGL02730:Lrba	APN	3	86,328,199 (GRCm38)	missense	probably damaging	1.00
IGL02883:Lrba	APN	3	86,354,206 (GRCm38)	missense	probably damaging	1.00
IGL02948:Lrba	APN	3	86,310,384 (GRCm38)	splice site	probably null
IGL03090:Lrba	APN	3	86,773,141 (GRCm38)	missense	probably benign	0.01
molasses	UTSW	3	86,354,307 (GRCm38)	critical splice donor site	probably null
oscar	UTSW	3	86,350,304 (GRCm38)	nonsense	probably null
oscar2	UTSW	3	86,664,458 (GRCm38)	nonsense	probably null
P0023:Lrba	UTSW	3	86,417,935 (GRCm38)	missense	probably damaging	1.00
PIT4802001:Lrba	UTSW	3	86,664,494 (GRCm38)	nonsense	probably null
R0077:Lrba	UTSW	3	86,542,688 (GRCm38)	missense	probably damaging	0.99
R0189:Lrba	UTSW	3	86,368,509 (GRCm38)	missense	probably damaging	1.00
R0217:Lrba	UTSW	3	86,642,722 (GRCm38)	missense	probably damaging	1.00
R0349:Lrba	UTSW	3	86,540,005 (GRCm38)	missense	probably damaging	1.00
R0396:Lrba	UTSW	3	86,295,179 (GRCm38)	missense	probably damaging	1.00
R0417:Lrba	UTSW	3	86,715,654 (GRCm38)	missense	probably damaging	1.00
R0536:Lrba	UTSW	3	86,715,532 (GRCm38)	missense	probably damaging	1.00
R0712:Lrba	UTSW	3	86,297,990 (GRCm38)	nonsense	probably null
R0722:Lrba	UTSW	3	86,605,989 (GRCm38)	critical splice donor site	probably null
R0828:Lrba	UTSW	3	86,608,370 (GRCm38)	splice site	probably null
R0927:Lrba	UTSW	3	86,780,233 (GRCm38)	missense	probably damaging	1.00
R1120:Lrba	UTSW	3	86,295,192 (GRCm38)	missense	probably damaging	1.00
R1141:Lrba	UTSW	3	86,619,558 (GRCm38)	missense	probably damaging	1.00
R1276:Lrba	UTSW	3	86,664,526 (GRCm38)	missense	probably damaging	1.00
R1449:Lrba	UTSW	3	86,354,278 (GRCm38)	missense	probably damaging	1.00
R1470:Lrba	UTSW	3	86,737,142 (GRCm38)	missense	probably damaging	1.00
R1470:Lrba	UTSW	3	86,737,142 (GRCm38)	missense	probably damaging	1.00
R1474:Lrba	UTSW	3	86,780,266 (GRCm38)	splice site	probably benign
R1558:Lrba	UTSW	3	86,351,315 (GRCm38)	missense	probably damaging	1.00
R1596:Lrba	UTSW	3	86,350,304 (GRCm38)	nonsense	probably null
R1652:Lrba	UTSW	3	86,539,938 (GRCm38)	missense	probably damaging	1.00
R1800:Lrba	UTSW	3	86,351,868 (GRCm38)	missense	probably benign	0.00
R1819:Lrba	UTSW	3	86,542,634 (GRCm38)	missense	possibly damaging	0.80
R1862:Lrba	UTSW	3	86,773,203 (GRCm38)	critical splice donor site	probably null
R1917:Lrba	UTSW	3	86,664,501 (GRCm38)	missense	probably damaging	1.00
R1965:Lrba	UTSW	3	86,605,868 (GRCm38)	critical splice acceptor site	probably null
R1966:Lrba	UTSW	3	86,605,868 (GRCm38)	critical splice acceptor site	probably null
R1969:Lrba	UTSW	3	86,608,389 (GRCm38)	missense	probably damaging	0.99
R2011:Lrba	UTSW	3	86,310,017 (GRCm38)	missense	probably damaging	0.99
R2179:Lrba	UTSW	3	86,354,281 (GRCm38)	missense	probably damaging	1.00
R2186:Lrba	UTSW	3	86,304,336 (GRCm38)	missense	probably damaging	1.00
R2281:Lrba	UTSW	3	86,776,103 (GRCm38)	missense	possibly damaging	0.46
R2359:Lrba	UTSW	3	86,348,750 (GRCm38)	missense	probably benign	0.01
R2412:Lrba	UTSW	3	86,327,700 (GRCm38)	missense	probably damaging	1.00
R2496:Lrba	UTSW	3	86,532,087 (GRCm38)	missense	probably damaging	1.00
R3153:Lrba	UTSW	3	86,285,219 (GRCm38)	missense	probably damaging	0.99
R3708:Lrba	UTSW	3	86,285,024 (GRCm38)	missense	possibly damaging	0.80
R3746:Lrba	UTSW	3	86,375,953 (GRCm38)	missense	probably damaging	1.00
R3747:Lrba	UTSW	3	86,375,953 (GRCm38)	missense	probably damaging	1.00
R3748:Lrba	UTSW	3	86,375,953 (GRCm38)	missense	probably damaging	1.00
R3749:Lrba	UTSW	3	86,375,953 (GRCm38)	missense	probably damaging	1.00
R3750:Lrba	UTSW	3	86,375,953 (GRCm38)	missense	probably damaging	1.00
R3758:Lrba	UTSW	3	86,776,049 (GRCm38)	missense	probably damaging	0.99
R3975:Lrba	UTSW	3	86,351,255 (GRCm38)	missense	probably damaging	1.00
R4210:Lrba	UTSW	3	86,360,126 (GRCm38)	missense	probably damaging	1.00
R4258:Lrba	UTSW	3	86,445,349 (GRCm38)	missense	probably damaging	1.00
R4657:Lrba	UTSW	3	86,737,164 (GRCm38)	missense	probably damaging	1.00
R4713:Lrba	UTSW	3	86,359,868 (GRCm38)	missense	probably benign	0.13
R4716:Lrba	UTSW	3	86,642,714 (GRCm38)	missense	probably damaging	0.99
R4811:Lrba	UTSW	3	86,776,141 (GRCm38)	missense	probably damaging	1.00
R4827:Lrba	UTSW	3	86,360,150 (GRCm38)	missense	possibly damaging	0.85
R4840:Lrba	UTSW	3	86,619,509 (GRCm38)	critical splice acceptor site	probably null
R4920:Lrba	UTSW	3	86,664,458 (GRCm38)	nonsense	probably null
R4948:Lrba	UTSW	3	86,285,028 (GRCm38)	missense	probably damaging	1.00
R4970:Lrba	UTSW	3	86,225,371 (GRCm38)	missense	probably benign	0.23
R4985:Lrba	UTSW	3	86,327,436 (GRCm38)	splice site	probably null
R4993:Lrba	UTSW	3	86,360,037 (GRCm38)	missense	probably damaging	1.00
R5107:Lrba	UTSW	3	86,359,779 (GRCm38)	missense	possibly damaging	0.47
R5112:Lrba	UTSW	3	86,225,371 (GRCm38)	missense	probably benign	0.23
R5122:Lrba	UTSW	3	86,349,154 (GRCm38)	nonsense	probably null
R5155:Lrba	UTSW	3	86,351,300 (GRCm38)	missense	probably benign	0.25
R5194:Lrba	UTSW	3	86,328,219 (GRCm38)	missense	probably damaging	1.00
R5280:Lrba	UTSW	3	86,325,022 (GRCm38)	missense	possibly damaging	0.94
R5445:Lrba	UTSW	3	86,368,595 (GRCm38)	missense	probably benign
R5469:Lrba	UTSW	3	86,542,641 (GRCm38)	missense	probably damaging	1.00
R5513:Lrba	UTSW	3	86,542,641 (GRCm38)	missense	probably damaging	1.00
R5578:Lrba	UTSW	3	86,757,507 (GRCm38)	missense	probably benign	0.27
R5740:Lrba	UTSW	3	86,328,342 (GRCm38)	missense	probably damaging	1.00
R5868:Lrba	UTSW	3	86,319,604 (GRCm38)	missense	probably damaging	1.00
R6104:Lrba	UTSW	3	86,353,792 (GRCm38)	missense	probably damaging	1.00
R6166:Lrba	UTSW	3	86,354,307 (GRCm38)	critical splice donor site	probably null
R6279:Lrba	UTSW	3	86,348,864 (GRCm38)	missense	probably benign	0.26
R6330:Lrba	UTSW	3	86,348,357 (GRCm38)	missense	probably benign	0.07
R6367:Lrba	UTSW	3	86,368,562 (GRCm38)	missense	probably benign	0.42
R6571:Lrba	UTSW	3	86,360,060 (GRCm38)	missense	probably damaging	1.00
R6584:Lrba	UTSW	3	86,664,576 (GRCm38)	missense	probably damaging	1.00
R6698:Lrba	UTSW	3	86,304,425 (GRCm38)	missense	probably damaging	0.99
R6763:Lrba	UTSW	3	86,354,263 (GRCm38)	missense	probably damaging	1.00
R6834:Lrba	UTSW	3	86,350,286 (GRCm38)	missense	probably benign	0.00
R6951:Lrba	UTSW	3	86,745,873 (GRCm38)	missense	probably benign	0.01
R6969:Lrba	UTSW	3	86,619,590 (GRCm38)	missense	probably benign	0.21
R7045:Lrba	UTSW	3	86,285,091 (GRCm38)	missense	probably benign	0.03
R7133:Lrba	UTSW	3	86,394,931 (GRCm38)	splice site	probably null
R7182:Lrba	UTSW	3	86,741,458 (GRCm38)	frame shift	probably null
R7214:Lrba	UTSW	3	86,328,326 (GRCm38)	missense	probably damaging	1.00
R7224:Lrba	UTSW	3	86,395,246 (GRCm38)	missense	probably damaging	1.00
R7243:Lrba	UTSW	3	86,751,516 (GRCm38)	splice site	probably null
R7350:Lrba	UTSW	3	86,351,902 (GRCm38)	missense	probably damaging	0.96
R7380:Lrba	UTSW	3	86,325,074 (GRCm38)	missense	probably damaging	1.00
R7492:Lrba	UTSW	3	86,664,528 (GRCm38)	missense	probably damaging	1.00
R7651:Lrba	UTSW	3	86,741,466 (GRCm38)	nonsense	probably null
R7729:Lrba	UTSW	3	86,318,167 (GRCm38)	missense	probably damaging	1.00
R7754:Lrba	UTSW	3	86,445,397 (GRCm38)	missense	probably damaging	1.00
R7762:Lrba	UTSW	3	86,532,201 (GRCm38)	missense	probably damaging	0.99
R7855:Lrba	UTSW	3	86,315,430 (GRCm38)	missense	possibly damaging	0.94
R7867:Lrba	UTSW	3	86,368,589 (GRCm38)	missense	probably damaging	1.00
R7912:Lrba	UTSW	3	86,715,565 (GRCm38)	missense	probably damaging	1.00
R7995:Lrba	UTSW	3	86,619,551 (GRCm38)	missense	probably damaging	1.00
R8013:Lrba	UTSW	3	86,417,971 (GRCm38)	missense	probably damaging	1.00
R8014:Lrba	UTSW	3	86,417,971 (GRCm38)	missense	probably damaging	1.00
R8024:Lrba	UTSW	3	86,295,401 (GRCm38)	nonsense	probably null
R8027:Lrba	UTSW	3	86,417,912 (GRCm38)	missense	probably benign	0.05
R8090:Lrba	UTSW	3	86,348,489 (GRCm38)	missense	probably benign
R8111:Lrba	UTSW	3	86,327,705 (GRCm38)	missense	probably damaging	1.00
R8118:Lrba	UTSW	3	86,354,226 (GRCm38)	missense	probably benign
R8204:Lrba	UTSW	3	86,315,403 (GRCm38)	missense	possibly damaging	0.95
R8239:Lrba	UTSW	3	86,542,575 (GRCm38)	missense	probably damaging	1.00
R8509:Lrba	UTSW	3	86,348,176 (GRCm38)	missense	probably benign	0.04
R8532:Lrba	UTSW	3	86,757,483 (GRCm38)	missense	probably damaging	1.00
R8726:Lrba	UTSW	3	86,353,755 (GRCm38)	missense	probably benign
R8744:Lrba	UTSW	3	86,304,333 (GRCm38)	missense	probably benign	0.08
R8782:Lrba	UTSW	3	86,642,669 (GRCm38)	missense	probably benign	0.00
R8784:Lrba	UTSW	3	86,375,928 (GRCm38)	missense	probably damaging	1.00
R8922:Lrba	UTSW	3	86,356,666 (GRCm38)	missense	probably damaging	1.00
R8964:Lrba	UTSW	3	86,351,245 (GRCm38)	missense	probably benign	0.22
R8971:Lrba	UTSW	3	86,615,081 (GRCm38)	missense	probably benign	0.00
R9046:Lrba	UTSW	3	86,395,236 (GRCm38)	missense	possibly damaging	0.94
R9155:Lrba	UTSW	3	86,295,201 (GRCm38)	missense	probably damaging	1.00
R9236:Lrba	UTSW	3	86,353,759 (GRCm38)	missense	probably benign	0.05
R9266:Lrba	UTSW	3	86,291,467 (GRCm38)	missense	probably benign	0.08
R9297:Lrba	UTSW	3	86,373,566 (GRCm38)	missense	probably damaging	1.00
R9404:Lrba	UTSW	3	86,297,917 (GRCm38)	missense	probably damaging	0.99
R9617:Lrba	UTSW	3	86,359,862 (GRCm38)	missense	probably benign
R9640:Lrba	UTSW	3	86,619,568 (GRCm38)	nonsense	probably null
R9779:Lrba	UTSW	3	86,325,771 (GRCm38)	missense	probably damaging	1.00
X0065:Lrba	UTSW	3	86,325,089 (GRCm38)	missense	possibly damaging	0.95
X0065:Lrba	UTSW	3	86,297,899 (GRCm38)	missense	probably damaging	1.00
Z1176:Lrba	UTSW	3	86,751,532 (GRCm38)	missense	possibly damaging	0.85
Z1176:Lrba	UTSW	3	86,715,538 (GRCm38)	missense	probably benign	0.31
Z1177:Lrba	UTSW	3	86,540,049 (GRCm38)	missense	probably null	1.00

Posted On

2015-12-18