Incidental Mutation 'R0362:Rp1l1'
| ID |
36290 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rp1l1
|
| Ensembl Gene |
ENSMUSG00000046049 |
| Gene Name |
retinitis pigmentosa 1 homolog like 1 |
| Synonyms |
Dcdc4, Rp1hl1 |
| MMRRC Submission |
038568-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.078)
|
| Stock # |
R0362 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
14 |
| Chromosomal Location |
64229880-64270955 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
T to A
at 64268515 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Stop codon
at position 1367
(L1367*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000055449
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000058229]
|
| AlphaFold |
Q8CGM2 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000058229
AA Change: L1367*
|
| SMART Domains |
Protein: ENSMUSP00000055449
Gene: ENSMUSG00000046049
AA Change: L1367*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
21 |
N/A |
INTRINSIC |
|
DCX
|
37 |
121 |
1.58e-13 |
SMART |
|
DCX
|
155 |
239 |
1e-15 |
SMART |
|
low complexity region
|
709 |
728 |
N/A |
INTRINSIC |
|
low complexity region
|
870 |
884 |
N/A |
INTRINSIC |
|
low complexity region
|
1159 |
1177 |
N/A |
INTRINSIC |
|
low complexity region
|
1228 |
1239 |
N/A |
INTRINSIC |
|
low complexity region
|
1612 |
1618 |
N/A |
INTRINSIC |
|
low complexity region
|
1642 |
1652 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000224314
|
| Meta Mutation Damage Score |
0.9755 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.6%
- 10x: 96.8%
- 20x: 94.0%
|
| Validation Efficiency |
99% (104/105) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the doublecortin family. This protein is a retinal-specific protein. It contains two N-terminal doublecortin domains, which can assemble and stabilize axonemal microtubules, but lacks the C-terminal repetitive regions including the 16aa repeat found in human RP1L1. This protein and the RP1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. [provided by RefSeq, Sep 2010]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit retinal photoreceptor abnormalities, including scattered outer segment disorganization, reduced electroretinogram amplitudes, and progressive retinal rod cell degeneration. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 103 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4932414N04Rik |
A |
G |
2: 68,563,261 (GRCm39) |
Q401R |
probably benign |
Het |
| Acp3 |
A |
G |
9: 104,191,626 (GRCm39) |
F220S |
probably damaging |
Het |
| Adam7 |
A |
G |
14: 68,747,105 (GRCm39) |
|
probably benign |
Het |
| Adamts6 |
A |
G |
13: 104,526,584 (GRCm39) |
|
probably null |
Het |
| Ascc3 |
T |
C |
10: 50,625,051 (GRCm39) |
|
probably benign |
Het |
| Atg10 |
T |
C |
13: 91,189,109 (GRCm39) |
|
probably null |
Het |
| Atm |
T |
C |
9: 53,370,138 (GRCm39) |
I2325V |
possibly damaging |
Het |
| Btnl9 |
C |
T |
11: 49,060,443 (GRCm39) |
R435H |
possibly damaging |
Het |
| Ccdc180 |
A |
G |
4: 45,923,551 (GRCm39) |
K1111E |
probably damaging |
Het |
| Ciao2b |
T |
C |
8: 105,368,222 (GRCm39) |
D34G |
probably null |
Het |
| Col11a2 |
T |
A |
17: 34,281,420 (GRCm39) |
|
probably null |
Het |
| Ctcfl |
A |
G |
2: 172,960,236 (GRCm39) |
W116R |
probably damaging |
Het |
| Ctsk |
A |
T |
3: 95,408,255 (GRCm39) |
Y37F |
probably damaging |
Het |
| Daam2 |
G |
C |
17: 49,787,813 (GRCm39) |
|
probably null |
Het |
| Dcdc2b |
T |
C |
4: 129,504,031 (GRCm39) |
|
probably null |
Het |
| Ddx28 |
C |
T |
8: 106,737,926 (GRCm39) |
R44Q |
probably damaging |
Het |
| Dhx29 |
T |
A |
13: 113,099,393 (GRCm39) |
N1139K |
probably benign |
Het |
| Dnah17 |
A |
T |
11: 117,989,365 (GRCm39) |
M1281K |
probably benign |
Het |
| Dnah6 |
T |
C |
6: 73,185,592 (GRCm39) |
S110G |
probably benign |
Het |
| Drc7 |
T |
C |
8: 95,799,483 (GRCm39) |
Y553H |
probably benign |
Het |
| Dync2h1 |
T |
C |
9: 7,005,487 (GRCm39) |
|
probably null |
Het |
| Ecm1 |
A |
G |
3: 95,644,369 (GRCm39) |
I152T |
possibly damaging |
Het |
| Edc4 |
C |
G |
8: 106,613,407 (GRCm39) |
P307R |
probably damaging |
Het |
| Eeig2 |
C |
T |
3: 108,887,497 (GRCm39) |
E256K |
probably benign |
Het |
| Egr1 |
A |
G |
18: 34,996,366 (GRCm39) |
T383A |
possibly damaging |
Het |
| Eml2 |
A |
G |
7: 18,924,731 (GRCm39) |
|
probably null |
Het |
| Eno4 |
A |
G |
19: 58,932,056 (GRCm39) |
|
probably benign |
Het |
| Erbb4 |
A |
T |
1: 68,369,429 (GRCm39) |
I404K |
probably damaging |
Het |
| Exoc7 |
G |
T |
11: 116,186,488 (GRCm39) |
T310K |
probably benign |
Het |
| Fam83e |
G |
T |
7: 45,376,393 (GRCm39) |
V369L |
probably benign |
Het |
| Fancc |
A |
T |
13: 63,545,970 (GRCm39) |
I91K |
possibly damaging |
Het |
| Fbn1 |
T |
C |
2: 125,151,697 (GRCm39) |
Q2519R |
probably damaging |
Het |
| Fhod3 |
T |
A |
18: 25,223,133 (GRCm39) |
C826* |
probably null |
Het |
| Foxi3 |
A |
G |
6: 70,933,612 (GRCm39) |
D33G |
probably benign |
Het |
| Gcn1 |
T |
C |
5: 115,714,167 (GRCm39) |
|
probably benign |
Het |
| Gm14221 |
T |
C |
2: 160,410,310 (GRCm39) |
|
noncoding transcript |
Het |
| Golga4 |
T |
A |
9: 118,384,853 (GRCm39) |
H630Q |
probably benign |
Het |
| Gpat4 |
T |
C |
8: 23,670,949 (GRCm39) |
S88G |
probably benign |
Het |
| Gucy2d |
A |
T |
7: 98,092,892 (GRCm39) |
S90C |
probably damaging |
Het |
| Has2 |
A |
C |
15: 56,545,057 (GRCm39) |
C182G |
probably damaging |
Het |
| Heatr5a |
A |
T |
12: 51,935,644 (GRCm39) |
S1647R |
probably damaging |
Het |
| Ifi35 |
T |
C |
11: 101,348,038 (GRCm39) |
V48A |
probably benign |
Het |
| Lig1 |
T |
A |
7: 13,030,730 (GRCm39) |
|
probably benign |
Het |
| Magi2 |
A |
G |
5: 19,432,573 (GRCm39) |
K96R |
probably damaging |
Het |
| Map7d1 |
G |
T |
4: 126,128,787 (GRCm39) |
P462Q |
probably damaging |
Het |
| Mdn1 |
A |
T |
4: 32,746,439 (GRCm39) |
|
probably null |
Het |
| Mfsd4a |
A |
T |
1: 131,987,013 (GRCm39) |
V105E |
probably damaging |
Het |
| Mrpl53 |
C |
T |
6: 83,086,526 (GRCm39) |
R77C |
probably damaging |
Het |
| Mtnr1b |
C |
T |
9: 15,785,600 (GRCm39) |
V53M |
probably damaging |
Het |
| Myo9b |
T |
C |
8: 71,800,414 (GRCm39) |
W990R |
probably damaging |
Het |
| Myt1 |
A |
T |
2: 181,405,186 (GRCm39) |
|
probably benign |
Het |
| Nf1 |
C |
T |
11: 79,427,704 (GRCm39) |
A1766V |
probably damaging |
Het |
| Nlrp3 |
T |
C |
11: 59,439,623 (GRCm39) |
V400A |
possibly damaging |
Het |
| Nup205 |
T |
A |
6: 35,173,649 (GRCm39) |
|
probably null |
Het |
| Nxf1 |
T |
C |
19: 8,741,515 (GRCm39) |
|
probably null |
Het |
| Or7a36 |
A |
T |
10: 78,820,220 (GRCm39) |
M199L |
probably benign |
Het |
| P4hb |
T |
C |
11: 120,454,162 (GRCm39) |
K311E |
probably benign |
Het |
| Pafah1b1 |
T |
C |
11: 74,574,457 (GRCm39) |
N243S |
probably benign |
Het |
| Parp8 |
G |
A |
13: 117,061,504 (GRCm39) |
Q141* |
probably null |
Het |
| Pkd2l2 |
A |
C |
18: 34,568,380 (GRCm39) |
D543A |
probably benign |
Het |
| Pld5 |
A |
T |
1: 175,803,146 (GRCm39) |
L311* |
probably null |
Het |
| Plekha5 |
G |
A |
6: 140,537,473 (GRCm39) |
R646K |
possibly damaging |
Het |
| Plpp5 |
A |
T |
8: 26,214,219 (GRCm39) |
T144S |
probably benign |
Het |
| Ppp6r3 |
A |
G |
19: 3,528,285 (GRCm39) |
L542S |
probably damaging |
Het |
| Prkar2b |
A |
T |
12: 32,037,973 (GRCm39) |
|
probably null |
Het |
| Psmg1 |
A |
T |
16: 95,789,171 (GRCm39) |
S129T |
possibly damaging |
Het |
| Radil |
T |
C |
5: 142,529,582 (GRCm39) |
D38G |
probably benign |
Het |
| Ric1 |
T |
C |
19: 29,578,411 (GRCm39) |
|
probably null |
Het |
| Rxfp1 |
A |
T |
3: 79,645,100 (GRCm39) |
M1K |
probably null |
Het |
| Serpina6 |
G |
T |
12: 103,618,208 (GRCm39) |
L202I |
probably damaging |
Het |
| Simc1 |
T |
C |
13: 54,676,280 (GRCm39) |
I98T |
probably damaging |
Het |
| Slc17a6 |
A |
G |
7: 51,308,519 (GRCm39) |
Y281C |
probably damaging |
Het |
| Slc26a11 |
T |
A |
11: 119,270,767 (GRCm39) |
|
probably benign |
Het |
| Slc34a1 |
T |
A |
13: 55,550,711 (GRCm39) |
|
probably null |
Het |
| Slfn10-ps |
T |
A |
11: 82,926,600 (GRCm39) |
|
noncoding transcript |
Het |
| Sohlh2 |
A |
G |
3: 55,115,163 (GRCm39) |
N383D |
probably damaging |
Het |
| Spag6 |
T |
A |
2: 18,715,302 (GRCm39) |
L27H |
probably damaging |
Het |
| Sptlc3 |
A |
G |
2: 139,388,475 (GRCm39) |
|
probably benign |
Het |
| St3gal4 |
T |
A |
9: 34,964,469 (GRCm39) |
K199* |
probably null |
Het |
| Stat5a |
T |
A |
11: 100,772,909 (GRCm39) |
D712E |
probably benign |
Het |
| Stmn2 |
A |
T |
3: 8,610,750 (GRCm39) |
D78V |
probably damaging |
Het |
| Stpg1 |
C |
T |
4: 135,233,777 (GRCm39) |
P20S |
possibly damaging |
Het |
| Taf2 |
A |
T |
15: 54,909,325 (GRCm39) |
V640E |
probably damaging |
Het |
| Tbce |
T |
C |
13: 14,172,747 (GRCm39) |
E501G |
probably benign |
Het |
| Tecpr2 |
A |
G |
12: 110,935,374 (GRCm39) |
S1398G |
probably damaging |
Het |
| Tenm4 |
T |
A |
7: 96,421,242 (GRCm39) |
Y598* |
probably null |
Het |
| Ticrr |
A |
G |
7: 79,327,088 (GRCm39) |
S599G |
probably damaging |
Het |
| Tnc |
A |
C |
4: 63,935,679 (GRCm39) |
V419G |
probably damaging |
Het |
| Trappc1 |
C |
A |
11: 69,216,402 (GRCm39) |
P110T |
probably benign |
Het |
| Trbv12-2 |
C |
T |
6: 41,095,993 (GRCm39) |
|
probably benign |
Het |
| Ttbk2 |
A |
T |
2: 120,576,264 (GRCm39) |
N835K |
possibly damaging |
Het |
| Tubgcp5 |
A |
G |
7: 55,450,432 (GRCm39) |
D181G |
probably damaging |
Het |
| Tut1 |
T |
C |
19: 8,932,891 (GRCm39) |
Y75H |
possibly damaging |
Het |
| Ulk2 |
C |
A |
11: 61,678,412 (GRCm39) |
C769F |
probably benign |
Het |
| Vdac1 |
T |
C |
11: 52,265,800 (GRCm39) |
|
probably benign |
Het |
| Vmn2r124 |
T |
C |
17: 18,284,486 (GRCm39) |
|
probably null |
Het |
| Vps8 |
T |
C |
16: 21,426,977 (GRCm39) |
|
probably benign |
Het |
| Wdr35 |
T |
C |
12: 9,045,625 (GRCm39) |
|
probably benign |
Het |
| Zdhhc7 |
T |
A |
8: 120,813,386 (GRCm39) |
E141V |
probably null |
Het |
| Zfp12 |
C |
A |
5: 143,230,978 (GRCm39) |
S435Y |
probably damaging |
Het |
| Zfp974 |
A |
T |
7: 27,626,819 (GRCm39) |
|
probably benign |
Het |
| Zfyve9 |
T |
A |
4: 108,538,166 (GRCm39) |
K1033N |
probably damaging |
Het |
| Zswim8 |
T |
A |
14: 20,772,013 (GRCm39) |
S1572T |
possibly damaging |
Het |
|
| Other mutations in Rp1l1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00494:Rp1l1
|
APN |
14 |
64,266,174 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02063:Rp1l1
|
APN |
14 |
64,266,985 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02132:Rp1l1
|
APN |
14 |
64,266,259 (GRCm39) |
missense |
probably benign |
|
|
IGL02430:Rp1l1
|
APN |
14 |
64,266,735 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02977:Rp1l1
|
APN |
14 |
64,265,599 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03213:Rp1l1
|
APN |
14 |
64,265,864 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03346:Rp1l1
|
APN |
14 |
64,266,889 (GRCm39) |
missense |
probably benign |
|
|
R0085:Rp1l1
|
UTSW |
14 |
64,259,744 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0347:Rp1l1
|
UTSW |
14 |
64,268,253 (GRCm39) |
nonsense |
probably null |
|
|
R0369:Rp1l1
|
UTSW |
14 |
64,266,837 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0538:Rp1l1
|
UTSW |
14 |
64,259,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0544:Rp1l1
|
UTSW |
14 |
64,269,515 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0780:Rp1l1
|
UTSW |
14 |
64,267,800 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0944:Rp1l1
|
UTSW |
14 |
64,269,681 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1051:Rp1l1
|
UTSW |
14 |
64,269,984 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1126:Rp1l1
|
UTSW |
14 |
64,267,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1450:Rp1l1
|
UTSW |
14 |
64,265,599 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1483:Rp1l1
|
UTSW |
14 |
64,266,496 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R1508:Rp1l1
|
UTSW |
14 |
64,268,341 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1553:Rp1l1
|
UTSW |
14 |
64,269,343 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1651:Rp1l1
|
UTSW |
14 |
64,268,442 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1682:Rp1l1
|
UTSW |
14 |
64,266,417 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1809:Rp1l1
|
UTSW |
14 |
64,265,415 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1885:Rp1l1
|
UTSW |
14 |
64,265,839 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1887:Rp1l1
|
UTSW |
14 |
64,265,839 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1898:Rp1l1
|
UTSW |
14 |
64,269,039 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1924:Rp1l1
|
UTSW |
14 |
64,268,992 (GRCm39) |
missense |
probably benign |
|
|
R1939:Rp1l1
|
UTSW |
14 |
64,267,042 (GRCm39) |
missense |
probably benign |
|
|
R1941:Rp1l1
|
UTSW |
14 |
64,259,701 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2129:Rp1l1
|
UTSW |
14 |
64,266,415 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2363:Rp1l1
|
UTSW |
14 |
64,267,447 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R3894:Rp1l1
|
UTSW |
14 |
64,266,756 (GRCm39) |
missense |
probably benign |
|
|
R3974:Rp1l1
|
UTSW |
14 |
64,267,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3975:Rp1l1
|
UTSW |
14 |
64,267,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3976:Rp1l1
|
UTSW |
14 |
64,267,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4072:Rp1l1
|
UTSW |
14 |
64,265,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4672:Rp1l1
|
UTSW |
14 |
64,268,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4673:Rp1l1
|
UTSW |
14 |
64,268,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4749:Rp1l1
|
UTSW |
14 |
64,267,249 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4755:Rp1l1
|
UTSW |
14 |
64,267,519 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4877:Rp1l1
|
UTSW |
14 |
64,263,620 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4930:Rp1l1
|
UTSW |
14 |
64,269,655 (GRCm39) |
missense |
probably benign |
|
|
R5039:Rp1l1
|
UTSW |
14 |
64,268,805 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5106:Rp1l1
|
UTSW |
14 |
64,265,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5184:Rp1l1
|
UTSW |
14 |
64,267,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5215:Rp1l1
|
UTSW |
14 |
64,267,462 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5409:Rp1l1
|
UTSW |
14 |
64,268,070 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5575:Rp1l1
|
UTSW |
14 |
64,268,433 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5696:Rp1l1
|
UTSW |
14 |
64,267,195 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5739:Rp1l1
|
UTSW |
14 |
64,269,619 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5878:Rp1l1
|
UTSW |
14 |
64,266,355 (GRCm39) |
missense |
probably benign |
0.09 |
|
R6133:Rp1l1
|
UTSW |
14 |
64,267,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6134:Rp1l1
|
UTSW |
14 |
64,267,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6135:Rp1l1
|
UTSW |
14 |
64,267,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6428:Rp1l1
|
UTSW |
14 |
64,269,838 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6594:Rp1l1
|
UTSW |
14 |
64,269,126 (GRCm39) |
nonsense |
probably null |
|
|
R6736:Rp1l1
|
UTSW |
14 |
64,267,173 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6800:Rp1l1
|
UTSW |
14 |
64,268,599 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6848:Rp1l1
|
UTSW |
14 |
64,265,667 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R6878:Rp1l1
|
UTSW |
14 |
64,269,301 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6922:Rp1l1
|
UTSW |
14 |
64,267,834 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6980:Rp1l1
|
UTSW |
14 |
64,266,169 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7053:Rp1l1
|
UTSW |
14 |
64,268,958 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7151:Rp1l1
|
UTSW |
14 |
64,266,475 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R7291:Rp1l1
|
UTSW |
14 |
64,269,747 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7335:Rp1l1
|
UTSW |
14 |
64,269,447 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7344:Rp1l1
|
UTSW |
14 |
64,267,069 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7470:Rp1l1
|
UTSW |
14 |
64,266,015 (GRCm39) |
missense |
probably benign |
|
|
R7570:Rp1l1
|
UTSW |
14 |
64,269,023 (GRCm39) |
nonsense |
probably null |
|
|
R7585:Rp1l1
|
UTSW |
14 |
64,267,588 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7591:Rp1l1
|
UTSW |
14 |
64,263,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7667:Rp1l1
|
UTSW |
14 |
64,267,252 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7862:Rp1l1
|
UTSW |
14 |
64,265,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7935:Rp1l1
|
UTSW |
14 |
64,268,674 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8256:Rp1l1
|
UTSW |
14 |
64,265,602 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8403:Rp1l1
|
UTSW |
14 |
64,266,258 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8709:Rp1l1
|
UTSW |
14 |
64,269,295 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8817:Rp1l1
|
UTSW |
14 |
64,268,085 (GRCm39) |
missense |
probably benign |
|
|
R8971:Rp1l1
|
UTSW |
14 |
64,259,445 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9380:Rp1l1
|
UTSW |
14 |
64,266,475 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9438:Rp1l1
|
UTSW |
14 |
64,265,574 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9501:Rp1l1
|
UTSW |
14 |
64,266,039 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9652:Rp1l1
|
UTSW |
14 |
64,269,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9683:Rp1l1
|
UTSW |
14 |
64,269,126 (GRCm39) |
missense |
probably damaging |
0.97 |
|
X0057:Rp1l1
|
UTSW |
14 |
64,267,489 (GRCm39) |
missense |
probably benign |
0.14 |
|
X0063:Rp1l1
|
UTSW |
14 |
64,266,672 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1088:Rp1l1
|
UTSW |
14 |
64,267,827 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1088:Rp1l1
|
UTSW |
14 |
64,266,207 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
Z1176:Rp1l1
|
UTSW |
14 |
64,266,593 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Rp1l1
|
UTSW |
14 |
64,269,746 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTTCACCAGAAGATACCAGAGTGCC -3'
(R):5'- ACTTCCATAACAGTGCTTGCCTGC -3'
Sequencing Primer
(F):5'- TACCAGAGTGCCAACAGATG -3'
(R):5'- TGTCATGAAGATCCCATCGG -3'
|
| Posted On |
2013-05-09 |
Incidental Mutation