Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02884:Pkd1l2'

362905

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Pkd1l2

Ensembl Gene

ENSMUSG00000034416

Gene Name

polycystic kidney disease 1 like 2

Synonyms

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02884

Quality Score

Status

Chromosome

Chromosomal Location

116995679-117082449 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 117065745 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Isoleucine at position 436 (T436I)

Ref Sequence

ENSEMBL: ENSMUSP00000104721 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000098375] [ENSMUST00000109093]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000098375
AA Change: T436I

PolyPhen 2 Score 0.070 (Sensitivity: 0.94; Specificity: 0.84)

SMART Domains

Protein: ENSMUSP00000095977
Gene: ENSMUSG00000034416
AA Change: T436I

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
CLECT	26	152	1.56e-21	SMART
Pfam:Gal_Lectin	168	250	1.8e-18	PFAM
PKD	260	341	3.84e-1	SMART
low complexity region	496	507	N/A	INTRINSIC
Pfam:REJ	510	886	1.8e-13	PFAM
low complexity region	1050	1060	N/A	INTRINSIC
GPS	1278	1327	1.61e-11	SMART
transmembrane domain	1346	1365	N/A	INTRINSIC
LH2	1390	1509	6.05e-13	SMART
transmembrane domain	1552	1574	N/A	INTRINSIC
transmembrane domain	1589	1611	N/A	INTRINSIC
transmembrane domain	1815	1837	N/A	INTRINSIC
transmembrane domain	1852	1874	N/A	INTRINSIC
transmembrane domain	1940	1962	N/A	INTRINSIC
Pfam:PKD_channel	1980	2403	6.4e-107	PFAM
Pfam:Ion_trans	2187	2396	2.5e-12	PFAM
low complexity region	2441	2458	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000109093
AA Change: T436I

PolyPhen 2 Score 0.070 (Sensitivity: 0.94; Specificity: 0.84)

SMART Domains

Protein: ENSMUSP00000104721
Gene: ENSMUSG00000034416
AA Change: T436I

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
CLECT	26	152	1.56e-21	SMART
Pfam:Gal_Lectin	168	250	6.9e-19	PFAM
PKD	260	341	3.84e-1	SMART
low complexity region	496	507	N/A	INTRINSIC
Pfam:REJ	519	883	7e-11	PFAM
low complexity region	1051	1061	N/A	INTRINSIC
GPS	1279	1328	1.61e-11	SMART
transmembrane domain	1347	1366	N/A	INTRINSIC
LH2	1391	1510	6.05e-13	SMART
transmembrane domain	1553	1575	N/A	INTRINSIC
transmembrane domain	1590	1612	N/A	INTRINSIC
transmembrane domain	1816	1838	N/A	INTRINSIC
transmembrane domain	1853	1875	N/A	INTRINSIC
transmembrane domain	1941	1963	N/A	INTRINSIC
Pfam:PKD_channel	1981	2403	5.9e-106	PFAM
Pfam:Ion_trans	2138	2409	3.4e-12	PFAM
low complexity region	2442	2459	N/A	INTRINSIC

Meta Mutation Damage Score

0.0717

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. This gene appears to be a polymorphic pseudogene in humans, where some individuals contain a non-functional allele. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Allele List at MGI

Other mutations in this stock

Total: 53 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930438A08Rik	A	G	11: 58,287,476 (GRCm38)	I121V	probably benign	Het
Adprh	C	T	16: 38,446,034 (GRCm38)	V249I	probably benign	Het
Akap11	A	T	14: 78,498,962 (GRCm38)	M1797K	probably benign	Het
Akap6	T	A	12: 52,886,622 (GRCm38)	I299N	probably benign	Het
Akr1c12	A	T	13: 4,272,212 (GRCm38)	M277K	possibly damaging	Het
Ankrd17	A	T	5: 90,264,757 (GRCm38)	M1236K	probably damaging	Het
Arhgef11	A	G	3: 87,728,006 (GRCm38)	D874G	probably damaging	Het
Atg4b	T	C	1: 93,787,715 (GRCm38)		probably benign	Het
Bcl9	G	A	3: 97,210,052 (GRCm38)	P442L	probably damaging	Het
Ccdc107	A	T	4: 43,495,228 (GRCm38)	K98*	probably null	Het
Ccdc129	T	C	6: 55,874,354 (GRCm38)		probably null	Het
Cenpl	A	G	1: 161,086,049 (GRCm38)	Q343R	probably benign	Het
Cep104	T	C	4: 153,989,862 (GRCm38)	C524R	probably damaging	Het
Clec3b	C	T	9: 123,156,762 (GRCm38)	T75I	probably benign	Het
Col13a1	A	T	10: 61,905,285 (GRCm38)		probably benign	Het
Crot	C	T	5: 8,978,197 (GRCm38)		probably null	Het
Ddo	G	A	10: 40,637,364 (GRCm38)	V101I	probably benign	Het
Disp2	T	C	2: 118,787,551 (GRCm38)		probably benign	Het
Dnmt3b	A	C	2: 153,674,377 (GRCm38)	Y474S	probably damaging	Het
Dpp6	T	A	5: 27,634,556 (GRCm38)	N298K	possibly damaging	Het
Fbf1	C	T	11: 116,146,513 (GRCm38)	E940K	probably damaging	Het
Fgd6	A	G	10: 94,045,639 (GRCm38)		probably benign	Het
H2-M10.2	T	C	17: 36,284,676 (GRCm38)	R241G	probably damaging	Het
Haghl	A	T	17: 25,783,098 (GRCm38)	F207Y	possibly damaging	Het
Helt	G	A	8: 46,292,583 (GRCm38)	R88C	probably damaging	Het
Igf2bp2	T	C	16: 22,162,885 (GRCm38)	K27E	probably benign	Het
Il1b	T	C	2: 129,365,102 (GRCm38)	H246R	probably benign	Het
Kcnu1	C	T	8: 25,921,528 (GRCm38)	S167L	probably damaging	Het
Kif16b	A	T	2: 142,702,614 (GRCm38)		probably benign	Het
Myh7	A	T	14: 54,992,819 (GRCm38)	S19T	probably benign	Het
Ncaph2	T	C	15: 89,364,244 (GRCm38)		probably null	Het
Nlrp4c	T	C	7: 6,098,952 (GRCm38)	L879P	probably damaging	Het
Nqo2	T	A	13: 33,972,361 (GRCm38)	N19K	probably damaging	Het
Olfr456	C	T	6: 42,486,606 (GRCm38)	V196M	probably damaging	Het
Osbpl1a	C	A	18: 12,819,578 (GRCm38)	G93*	probably null	Het
Pdxdc1	A	G	16: 13,843,795 (GRCm38)	F459L	possibly damaging	Het
Phc2	A	T	4: 128,708,016 (GRCm38)	H88L	probably damaging	Het
Ptchd4	A	T	17: 42,502,449 (GRCm38)	T414S	possibly damaging	Het
Rab7b	A	G	1: 131,698,542 (GRCm38)	R103G	probably damaging	Het
Retnla	A	G	16: 48,842,580 (GRCm38)	Y3C	probably benign	Het
Samd7	G	A	3: 30,756,173 (GRCm38)	R113H	probably damaging	Het
Shisa9	G	A	16: 11,997,043 (GRCm38)		probably benign	Het
Soat1	A	T	1: 156,441,356 (GRCm38)	I208N	possibly damaging	Het
Stab1	C	A	14: 31,150,143 (GRCm38)		probably null	Het
Tti2	C	T	8: 31,151,477 (GRCm38)	L210F	possibly damaging	Het
Ube2v2	A	G	16: 15,556,485 (GRCm38)	V77A	probably benign	Het
Ubr5	T	C	15: 37,998,376 (GRCm38)	E1617G	probably damaging	Het
Vmn2r16	T	A	5: 109,360,891 (GRCm38)	I495K	possibly damaging	Het
Vwce	G	T	19: 10,646,579 (GRCm38)	R278L	possibly damaging	Het
Wdr26	C	T	1: 181,182,784 (GRCm38)	A551T	probably damaging	Het
Wee1	A	G	7: 110,126,062 (GRCm38)	I304V	probably benign	Het
Xrcc5	C	T	1: 72,346,237 (GRCm38)	H496Y	possibly damaging	Het
Zfp142	G	T	1: 74,571,983 (GRCm38)	S884R	probably damaging	Het

Other mutations in Pkd1l2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01338:Pkd1l2	APN	8	117,059,520 (GRCm38)	nonsense	probably null
IGL01353:Pkd1l2	APN	8	117,057,443 (GRCm38)	missense	probably benign	0.24
IGL01362:Pkd1l2	APN	8	117,021,856 (GRCm38)	missense	probably damaging	1.00
IGL01486:Pkd1l2	APN	8	117,059,592 (GRCm38)	missense	probably benign
IGL01672:Pkd1l2	APN	8	117,080,732 (GRCm38)	missense	possibly damaging	0.94
IGL01696:Pkd1l2	APN	8	117,056,387 (GRCm38)	missense	probably benign	0.12
IGL01819:Pkd1l2	APN	8	116,998,174 (GRCm38)	missense	probably damaging	1.00
IGL01833:Pkd1l2	APN	8	117,060,525 (GRCm38)	missense	probably benign	0.00
IGL01981:Pkd1l2	APN	8	117,016,916 (GRCm38)	missense	probably benign	0.04
IGL02066:Pkd1l2	APN	8	117,009,564 (GRCm38)	splice site	probably benign
IGL02381:Pkd1l2	APN	8	117,035,800 (GRCm38)	splice site	probably benign
IGL02416:Pkd1l2	APN	8	117,040,835 (GRCm38)	missense	possibly damaging	0.82
IGL02736:Pkd1l2	APN	8	117,040,666 (GRCm38)	missense	probably benign	0.00
IGL02828:Pkd1l2	APN	8	117,029,559 (GRCm38)	missense	probably benign
IGL02861:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL02862:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL02883:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL02894:Pkd1l2	APN	8	117,013,891 (GRCm38)	missense	probably damaging	0.97
IGL02900:Pkd1l2	APN	8	117,024,091 (GRCm38)	missense	probably benign	0.03
IGL02901:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL02929:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL02941:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL02957:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL02969:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL03028:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL03059:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL03065:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL03066:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL03083:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL03084:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL03124:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL03162:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL03165:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL03335:Pkd1l2	APN	8	117,065,745 (GRCm38)	missense	probably benign	0.07
IGL03357:Pkd1l2	APN	8	116,995,809 (GRCm38)	missense	probably damaging	1.00
IGL02835:Pkd1l2	UTSW	8	117,065,745 (GRCm38)	missense	probably benign	0.07
PIT4453001:Pkd1l2	UTSW	8	117,022,022 (GRCm38)	missense	probably benign	0.00
R0127:Pkd1l2	UTSW	8	117,050,048 (GRCm38)	splice site	probably benign
R0309:Pkd1l2	UTSW	8	116,997,576 (GRCm38)	missense	probably damaging	0.99
R0365:Pkd1l2	UTSW	8	117,021,850 (GRCm38)	missense	probably benign	0.02
R0526:Pkd1l2	UTSW	8	117,082,260 (GRCm38)	missense	probably damaging	1.00
R0571:Pkd1l2	UTSW	8	117,082,218 (GRCm38)	missense	probably benign	0.01
R0716:Pkd1l2	UTSW	8	117,051,100 (GRCm38)	missense	probably damaging	1.00
R0787:Pkd1l2	UTSW	8	117,076,177 (GRCm38)	missense	possibly damaging	0.90
R0893:Pkd1l2	UTSW	8	117,044,492 (GRCm38)	missense	probably damaging	0.99
R1256:Pkd1l2	UTSW	8	117,019,543 (GRCm38)	critical splice acceptor site	probably null
R1391:Pkd1l2	UTSW	8	117,054,934 (GRCm38)	missense	possibly damaging	0.87
R1474:Pkd1l2	UTSW	8	117,065,497 (GRCm38)	splice site	probably benign
R1491:Pkd1l2	UTSW	8	117,028,408 (GRCm38)	missense	probably damaging	1.00
R1520:Pkd1l2	UTSW	8	117,046,159 (GRCm38)	missense	probably benign	0.00
R1521:Pkd1l2	UTSW	8	117,065,500 (GRCm38)	splice site	probably null
R1544:Pkd1l2	UTSW	8	117,038,235 (GRCm38)	frame shift	probably null
R1558:Pkd1l2	UTSW	8	117,082,252 (GRCm38)	missense	possibly damaging	0.94
R1673:Pkd1l2	UTSW	8	117,040,775 (GRCm38)	missense	probably benign	0.00
R1691:Pkd1l2	UTSW	8	117,056,419 (GRCm38)	missense	possibly damaging	0.60
R1754:Pkd1l2	UTSW	8	117,030,719 (GRCm38)	missense	possibly damaging	0.81
R1857:Pkd1l2	UTSW	8	117,040,669 (GRCm38)	missense	possibly damaging	0.70
R1939:Pkd1l2	UTSW	8	117,046,182 (GRCm38)	nonsense	probably null
R1955:Pkd1l2	UTSW	8	117,043,361 (GRCm38)	missense	probably benign
R1957:Pkd1l2	UTSW	8	117,030,682 (GRCm38)	missense	probably damaging	1.00
R1959:Pkd1l2	UTSW	8	117,043,231 (GRCm38)	critical splice donor site	probably null
R2024:Pkd1l2	UTSW	8	117,019,533 (GRCm38)	missense	probably benign
R2046:Pkd1l2	UTSW	8	116,999,955 (GRCm38)	missense	probably damaging	1.00
R2102:Pkd1l2	UTSW	8	117,081,469 (GRCm38)	missense	probably damaging	0.98
R2116:Pkd1l2	UTSW	8	117,030,722 (GRCm38)	missense	possibly damaging	0.93
R2148:Pkd1l2	UTSW	8	117,056,325 (GRCm38)	missense	probably damaging	0.98
R2251:Pkd1l2	UTSW	8	117,057,438 (GRCm38)	missense	probably damaging	1.00
R2252:Pkd1l2	UTSW	8	117,057,438 (GRCm38)	missense	probably damaging	1.00
R2366:Pkd1l2	UTSW	8	117,043,317 (GRCm38)	missense	probably benign	0.01
R2566:Pkd1l2	UTSW	8	117,019,494 (GRCm38)	missense	probably damaging	1.00
R2872:Pkd1l2	UTSW	8	117,038,164 (GRCm38)	missense	probably benign	0.10
R2872:Pkd1l2	UTSW	8	117,038,164 (GRCm38)	missense	probably benign	0.10
R2985:Pkd1l2	UTSW	8	117,065,551 (GRCm38)	missense	probably benign	0.00
R3055:Pkd1l2	UTSW	8	117,068,315 (GRCm38)	critical splice acceptor site	probably null
R3436:Pkd1l2	UTSW	8	117,040,739 (GRCm38)	missense	probably benign	0.01
R4732:Pkd1l2	UTSW	8	116,995,842 (GRCm38)	critical splice acceptor site	probably null
R4733:Pkd1l2	UTSW	8	116,995,842 (GRCm38)	critical splice acceptor site	probably null
R4763:Pkd1l2	UTSW	8	117,019,429 (GRCm38)	missense	probably damaging	0.96
R4789:Pkd1l2	UTSW	8	117,011,575 (GRCm38)	missense	probably damaging	0.99
R4921:Pkd1l2	UTSW	8	117,054,885 (GRCm38)	missense	probably benign	0.03
R4921:Pkd1l2	UTSW	8	117,072,549 (GRCm38)	missense	probably damaging	0.97
R4999:Pkd1l2	UTSW	8	117,047,374 (GRCm38)	splice site	probably null
R5057:Pkd1l2	UTSW	8	117,055,008 (GRCm38)	missense	probably benign	0.21
R5209:Pkd1l2	UTSW	8	117,056,442 (GRCm38)	missense	probably benign	0.23
R5241:Pkd1l2	UTSW	8	117,035,118 (GRCm38)	missense	probably damaging	1.00
R5480:Pkd1l2	UTSW	8	117,030,649 (GRCm38)	missense	probably damaging	0.99
R5501:Pkd1l2	UTSW	8	117,065,830 (GRCm38)	missense	probably damaging	0.98
R5533:Pkd1l2	UTSW	8	117,068,116 (GRCm38)	missense	probably benign	0.03
R5582:Pkd1l2	UTSW	8	117,040,783 (GRCm38)	nonsense	probably null
R5610:Pkd1l2	UTSW	8	117,042,320 (GRCm38)	missense	probably benign	0.04
R5770:Pkd1l2	UTSW	8	117,055,018 (GRCm38)	missense	probably damaging	1.00
R5854:Pkd1l2	UTSW	8	117,065,746 (GRCm38)	missense	possibly damaging	0.48
R5867:Pkd1l2	UTSW	8	117,055,011 (GRCm38)	missense	probably damaging	0.96
R5881:Pkd1l2	UTSW	8	116,997,582 (GRCm38)	missense	probably damaging	0.99
R5906:Pkd1l2	UTSW	8	117,029,648 (GRCm38)	missense	probably damaging	1.00
R5909:Pkd1l2	UTSW	8	117,024,056 (GRCm38)	missense	probably benign	0.00
R6030:Pkd1l2	UTSW	8	117,043,237 (GRCm38)	missense	probably damaging	1.00
R6030:Pkd1l2	UTSW	8	117,043,237 (GRCm38)	missense	probably damaging	1.00
R6084:Pkd1l2	UTSW	8	117,013,987 (GRCm38)	missense	probably damaging	1.00
R6122:Pkd1l2	UTSW	8	117,082,368 (GRCm38)	missense	probably benign	0.02
R6216:Pkd1l2	UTSW	8	117,081,470 (GRCm38)	missense	probably damaging	1.00
R6406:Pkd1l2	UTSW	8	117,035,847 (GRCm38)	missense	probably damaging	0.99
R6417:Pkd1l2	UTSW	8	117,013,899 (GRCm38)	missense	probably damaging	1.00
R6420:Pkd1l2	UTSW	8	117,013,899 (GRCm38)	missense	probably damaging	1.00
R6601:Pkd1l2	UTSW	8	117,040,666 (GRCm38)	missense	probably benign	0.00
R6743:Pkd1l2	UTSW	8	117,030,631 (GRCm38)	missense	probably damaging	1.00
R7053:Pkd1l2	UTSW	8	117,013,942 (GRCm38)	missense	probably damaging	1.00
R7144:Pkd1l2	UTSW	8	117,076,131 (GRCm38)	nonsense	probably null
R7148:Pkd1l2	UTSW	8	117,080,786 (GRCm38)	missense	probably benign	0.00
R7169:Pkd1l2	UTSW	8	117,040,835 (GRCm38)	missense	possibly damaging	0.82
R7217:Pkd1l2	UTSW	8	116,995,797 (GRCm38)	missense	probably benign	0.24
R7310:Pkd1l2	UTSW	8	117,024,034 (GRCm38)	missense	probably benign
R7382:Pkd1l2	UTSW	8	117,054,871 (GRCm38)	missense	possibly damaging	0.95
R7397:Pkd1l2	UTSW	8	117,035,902 (GRCm38)	missense	possibly damaging	0.94
R7408:Pkd1l2	UTSW	8	117,028,479 (GRCm38)	missense	possibly damaging	0.77
R7437:Pkd1l2	UTSW	8	117,030,682 (GRCm38)	missense	probably damaging	0.96
R7492:Pkd1l2	UTSW	8	117,068,110 (GRCm38)	missense	probably damaging	1.00
R7496:Pkd1l2	UTSW	8	117,060,594 (GRCm38)	missense	possibly damaging	0.89
R7519:Pkd1l2	UTSW	8	117,065,529 (GRCm38)	missense	probably benign
R7590:Pkd1l2	UTSW	8	117,080,786 (GRCm38)	missense	probably benign	0.00
R7623:Pkd1l2	UTSW	8	117,029,645 (GRCm38)	missense	probably damaging	1.00
R7768:Pkd1l2	UTSW	8	117,054,860 (GRCm38)	critical splice donor site	probably null
R7897:Pkd1l2	UTSW	8	116,998,088 (GRCm38)	missense	possibly damaging	0.69
R7982:Pkd1l2	UTSW	8	117,051,187 (GRCm38)	missense	possibly damaging	0.70
R8024:Pkd1l2	UTSW	8	117,076,182 (GRCm38)	missense	possibly damaging	0.85
R8140:Pkd1l2	UTSW	8	117,047,497 (GRCm38)	missense	probably benign
R8145:Pkd1l2	UTSW	8	117,055,003 (GRCm38)	missense	probably benign
R8228:Pkd1l2	UTSW	8	117,065,775 (GRCm38)	missense	probably damaging	0.97
R8252:Pkd1l2	UTSW	8	117,040,733 (GRCm38)	missense	probably benign	0.29
R8500:Pkd1l2	UTSW	8	117,047,563 (GRCm38)	critical splice acceptor site	probably null
R8732:Pkd1l2	UTSW	8	117,065,572 (GRCm38)	missense	probably benign	0.28
R8809:Pkd1l2	UTSW	8	116,999,921 (GRCm38)	missense	probably damaging	1.00
R8896:Pkd1l2	UTSW	8	117,013,876 (GRCm38)	missense	possibly damaging	0.91
R8961:Pkd1l2	UTSW	8	116,999,978 (GRCm38)	missense	possibly damaging	0.52
R8985:Pkd1l2	UTSW	8	117,038,110 (GRCm38)	missense	probably benign	0.01
R9008:Pkd1l2	UTSW	8	117,042,298 (GRCm38)	missense	probably benign	0.32
R9091:Pkd1l2	UTSW	8	117,032,694 (GRCm38)	missense	probably damaging	1.00
R9138:Pkd1l2	UTSW	8	117,055,009 (GRCm38)	missense	probably benign	0.43
R9160:Pkd1l2	UTSW	8	117,040,669 (GRCm38)	missense	possibly damaging	0.70
R9249:Pkd1l2	UTSW	8	117,019,420 (GRCm38)	missense	probably damaging	0.99
R9270:Pkd1l2	UTSW	8	117,032,694 (GRCm38)	missense	probably damaging	1.00
R9735:Pkd1l2	UTSW	8	117,046,081 (GRCm38)	missense	possibly damaging	0.94
Z1176:Pkd1l2	UTSW	8	117,054,914 (GRCm38)	missense	probably damaging	1.00
Z1177:Pkd1l2	UTSW	8	117,030,691 (GRCm38)	missense	probably damaging	1.00

Posted On

2015-12-18