Incidental Mutation 'R0362:Vps8'
| ID |
36294 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Vps8
|
| Ensembl Gene |
ENSMUSG00000033653 |
| Gene Name |
VPS8 CORVET complex subunit |
| Synonyms |
|
| MMRRC Submission |
038568-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0362 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
21241868-21463430 bp(+) (GRCm39) |
| Type of Mutation |
intron |
| DNA Base Change (assembly) |
T to C
at 21426977 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000096192]
[ENSMUST00000115397]
[ENSMUST00000117598]
[ENSMUST00000118138]
[ENSMUST00000118923]
|
| AlphaFold |
Q0P5W1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000096192
|
| SMART Domains |
Protein: ENSMUSP00000093906
Gene: ENSMUSG00000033653
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
96 |
112 |
N/A |
INTRINSIC |
|
SCOP:d1g72a_
|
158 |
298 |
1e-8 |
SMART |
|
Blast:WD40
|
186 |
227 |
8e-22 |
BLAST |
|
Blast:WD40
|
230 |
270 |
5e-20 |
BLAST |
|
Pfam:Vps8
|
612 |
796 |
1.4e-61 |
PFAM |
|
low complexity region
|
969 |
979 |
N/A |
INTRINSIC |
|
low complexity region
|
1057 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1098 |
1109 |
N/A |
INTRINSIC |
|
RING
|
1229 |
1280 |
1.23e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000115397
|
| SMART Domains |
Protein: ENSMUSP00000111055
Gene: ENSMUSG00000033653
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
96 |
112 |
N/A |
INTRINSIC |
|
SCOP:d1g72a_
|
158 |
298 |
8e-9 |
SMART |
|
Blast:WD40
|
186 |
227 |
8e-22 |
BLAST |
|
Blast:WD40
|
230 |
270 |
5e-20 |
BLAST |
|
Pfam:Vps8
|
613 |
796 |
1.3e-61 |
PFAM |
|
low complexity region
|
994 |
1009 |
N/A |
INTRINSIC |
|
low complexity region
|
1087 |
1099 |
N/A |
INTRINSIC |
|
low complexity region
|
1128 |
1139 |
N/A |
INTRINSIC |
|
RING
|
1259 |
1310 |
1.23e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000117598
|
| SMART Domains |
Protein: ENSMUSP00000112937
Gene: ENSMUSG00000033653
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
96 |
112 |
N/A |
INTRINSIC |
|
SCOP:d1g72a_
|
158 |
296 |
1e-8 |
SMART |
|
Blast:WD40
|
184 |
225 |
8e-22 |
BLAST |
|
Blast:WD40
|
228 |
268 |
5e-20 |
BLAST |
|
Pfam:Vps8
|
610 |
794 |
1.9e-61 |
PFAM |
|
low complexity region
|
992 |
1007 |
N/A |
INTRINSIC |
|
low complexity region
|
1085 |
1097 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1137 |
N/A |
INTRINSIC |
|
RING
|
1257 |
1308 |
1.23e-4 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000118138
|
| SMART Domains |
Protein: ENSMUSP00000113447
Gene: ENSMUSG00000033653
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Vps8
|
1 |
76 |
7.7e-21 |
PFAM |
|
low complexity region
|
274 |
289 |
N/A |
INTRINSIC |
|
low complexity region
|
367 |
379 |
N/A |
INTRINSIC |
|
low complexity region
|
408 |
419 |
N/A |
INTRINSIC |
|
RING
|
539 |
590 |
1.23e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000118923
|
| SMART Domains |
Protein: ENSMUSP00000112636
Gene: ENSMUSG00000033653
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
96 |
112 |
N/A |
INTRINSIC |
|
SCOP:d1g72a_
|
158 |
298 |
9e-9 |
SMART |
|
Blast:WD40
|
186 |
227 |
8e-22 |
BLAST |
|
Blast:WD40
|
230 |
270 |
5e-20 |
BLAST |
|
Pfam:Vps8
|
612 |
796 |
1.9e-61 |
PFAM |
|
low complexity region
|
969 |
979 |
N/A |
INTRINSIC |
|
low complexity region
|
1057 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1098 |
1109 |
N/A |
INTRINSIC |
|
RING
|
1229 |
1280 |
1.23e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125487
|
| SMART Domains |
Protein: ENSMUSP00000114719
Gene: ENSMUSG00000033653
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Vps8
|
182 |
365 |
8.5e-62 |
PFAM |
|
low complexity region
|
563 |
578 |
N/A |
INTRINSIC |
|
low complexity region
|
656 |
668 |
N/A |
INTRINSIC |
|
low complexity region
|
697 |
708 |
N/A |
INTRINSIC |
|
RING
|
828 |
879 |
1.23e-4 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000231224
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000232132
|
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.6%
- 10x: 96.8%
- 20x: 94.0%
|
| Validation Efficiency |
99% (104/105) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 103 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4932414N04Rik |
A |
G |
2: 68,563,261 (GRCm39) |
Q401R |
probably benign |
Het |
| Acp3 |
A |
G |
9: 104,191,626 (GRCm39) |
F220S |
probably damaging |
Het |
| Adam7 |
A |
G |
14: 68,747,105 (GRCm39) |
|
probably benign |
Het |
| Adamts6 |
A |
G |
13: 104,526,584 (GRCm39) |
|
probably null |
Het |
| Ascc3 |
T |
C |
10: 50,625,051 (GRCm39) |
|
probably benign |
Het |
| Atg10 |
T |
C |
13: 91,189,109 (GRCm39) |
|
probably null |
Het |
| Atm |
T |
C |
9: 53,370,138 (GRCm39) |
I2325V |
possibly damaging |
Het |
| Btnl9 |
C |
T |
11: 49,060,443 (GRCm39) |
R435H |
possibly damaging |
Het |
| Ccdc180 |
A |
G |
4: 45,923,551 (GRCm39) |
K1111E |
probably damaging |
Het |
| Ciao2b |
T |
C |
8: 105,368,222 (GRCm39) |
D34G |
probably null |
Het |
| Col11a2 |
T |
A |
17: 34,281,420 (GRCm39) |
|
probably null |
Het |
| Ctcfl |
A |
G |
2: 172,960,236 (GRCm39) |
W116R |
probably damaging |
Het |
| Ctsk |
A |
T |
3: 95,408,255 (GRCm39) |
Y37F |
probably damaging |
Het |
| Daam2 |
G |
C |
17: 49,787,813 (GRCm39) |
|
probably null |
Het |
| Dcdc2b |
T |
C |
4: 129,504,031 (GRCm39) |
|
probably null |
Het |
| Ddx28 |
C |
T |
8: 106,737,926 (GRCm39) |
R44Q |
probably damaging |
Het |
| Dhx29 |
T |
A |
13: 113,099,393 (GRCm39) |
N1139K |
probably benign |
Het |
| Dnah17 |
A |
T |
11: 117,989,365 (GRCm39) |
M1281K |
probably benign |
Het |
| Dnah6 |
T |
C |
6: 73,185,592 (GRCm39) |
S110G |
probably benign |
Het |
| Drc7 |
T |
C |
8: 95,799,483 (GRCm39) |
Y553H |
probably benign |
Het |
| Dync2h1 |
T |
C |
9: 7,005,487 (GRCm39) |
|
probably null |
Het |
| Ecm1 |
A |
G |
3: 95,644,369 (GRCm39) |
I152T |
possibly damaging |
Het |
| Edc4 |
C |
G |
8: 106,613,407 (GRCm39) |
P307R |
probably damaging |
Het |
| Eeig2 |
C |
T |
3: 108,887,497 (GRCm39) |
E256K |
probably benign |
Het |
| Egr1 |
A |
G |
18: 34,996,366 (GRCm39) |
T383A |
possibly damaging |
Het |
| Eml2 |
A |
G |
7: 18,924,731 (GRCm39) |
|
probably null |
Het |
| Eno4 |
A |
G |
19: 58,932,056 (GRCm39) |
|
probably benign |
Het |
| Erbb4 |
A |
T |
1: 68,369,429 (GRCm39) |
I404K |
probably damaging |
Het |
| Exoc7 |
G |
T |
11: 116,186,488 (GRCm39) |
T310K |
probably benign |
Het |
| Fam83e |
G |
T |
7: 45,376,393 (GRCm39) |
V369L |
probably benign |
Het |
| Fancc |
A |
T |
13: 63,545,970 (GRCm39) |
I91K |
possibly damaging |
Het |
| Fbn1 |
T |
C |
2: 125,151,697 (GRCm39) |
Q2519R |
probably damaging |
Het |
| Fhod3 |
T |
A |
18: 25,223,133 (GRCm39) |
C826* |
probably null |
Het |
| Foxi3 |
A |
G |
6: 70,933,612 (GRCm39) |
D33G |
probably benign |
Het |
| Gcn1 |
T |
C |
5: 115,714,167 (GRCm39) |
|
probably benign |
Het |
| Gm14221 |
T |
C |
2: 160,410,310 (GRCm39) |
|
noncoding transcript |
Het |
| Golga4 |
T |
A |
9: 118,384,853 (GRCm39) |
H630Q |
probably benign |
Het |
| Gpat4 |
T |
C |
8: 23,670,949 (GRCm39) |
S88G |
probably benign |
Het |
| Gucy2d |
A |
T |
7: 98,092,892 (GRCm39) |
S90C |
probably damaging |
Het |
| Has2 |
A |
C |
15: 56,545,057 (GRCm39) |
C182G |
probably damaging |
Het |
| Heatr5a |
A |
T |
12: 51,935,644 (GRCm39) |
S1647R |
probably damaging |
Het |
| Ifi35 |
T |
C |
11: 101,348,038 (GRCm39) |
V48A |
probably benign |
Het |
| Lig1 |
T |
A |
7: 13,030,730 (GRCm39) |
|
probably benign |
Het |
| Magi2 |
A |
G |
5: 19,432,573 (GRCm39) |
K96R |
probably damaging |
Het |
| Map7d1 |
G |
T |
4: 126,128,787 (GRCm39) |
P462Q |
probably damaging |
Het |
| Mdn1 |
A |
T |
4: 32,746,439 (GRCm39) |
|
probably null |
Het |
| Mfsd4a |
A |
T |
1: 131,987,013 (GRCm39) |
V105E |
probably damaging |
Het |
| Mrpl53 |
C |
T |
6: 83,086,526 (GRCm39) |
R77C |
probably damaging |
Het |
| Mtnr1b |
C |
T |
9: 15,785,600 (GRCm39) |
V53M |
probably damaging |
Het |
| Myo9b |
T |
C |
8: 71,800,414 (GRCm39) |
W990R |
probably damaging |
Het |
| Myt1 |
A |
T |
2: 181,405,186 (GRCm39) |
|
probably benign |
Het |
| Nf1 |
C |
T |
11: 79,427,704 (GRCm39) |
A1766V |
probably damaging |
Het |
| Nlrp3 |
T |
C |
11: 59,439,623 (GRCm39) |
V400A |
possibly damaging |
Het |
| Nup205 |
T |
A |
6: 35,173,649 (GRCm39) |
|
probably null |
Het |
| Nxf1 |
T |
C |
19: 8,741,515 (GRCm39) |
|
probably null |
Het |
| Or7a36 |
A |
T |
10: 78,820,220 (GRCm39) |
M199L |
probably benign |
Het |
| P4hb |
T |
C |
11: 120,454,162 (GRCm39) |
K311E |
probably benign |
Het |
| Pafah1b1 |
T |
C |
11: 74,574,457 (GRCm39) |
N243S |
probably benign |
Het |
| Parp8 |
G |
A |
13: 117,061,504 (GRCm39) |
Q141* |
probably null |
Het |
| Pkd2l2 |
A |
C |
18: 34,568,380 (GRCm39) |
D543A |
probably benign |
Het |
| Pld5 |
A |
T |
1: 175,803,146 (GRCm39) |
L311* |
probably null |
Het |
| Plekha5 |
G |
A |
6: 140,537,473 (GRCm39) |
R646K |
possibly damaging |
Het |
| Plpp5 |
A |
T |
8: 26,214,219 (GRCm39) |
T144S |
probably benign |
Het |
| Ppp6r3 |
A |
G |
19: 3,528,285 (GRCm39) |
L542S |
probably damaging |
Het |
| Prkar2b |
A |
T |
12: 32,037,973 (GRCm39) |
|
probably null |
Het |
| Psmg1 |
A |
T |
16: 95,789,171 (GRCm39) |
S129T |
possibly damaging |
Het |
| Radil |
T |
C |
5: 142,529,582 (GRCm39) |
D38G |
probably benign |
Het |
| Ric1 |
T |
C |
19: 29,578,411 (GRCm39) |
|
probably null |
Het |
| Rp1l1 |
T |
A |
14: 64,268,515 (GRCm39) |
L1367* |
probably null |
Het |
| Rxfp1 |
A |
T |
3: 79,645,100 (GRCm39) |
M1K |
probably null |
Het |
| Serpina6 |
G |
T |
12: 103,618,208 (GRCm39) |
L202I |
probably damaging |
Het |
| Simc1 |
T |
C |
13: 54,676,280 (GRCm39) |
I98T |
probably damaging |
Het |
| Slc17a6 |
A |
G |
7: 51,308,519 (GRCm39) |
Y281C |
probably damaging |
Het |
| Slc26a11 |
T |
A |
11: 119,270,767 (GRCm39) |
|
probably benign |
Het |
| Slc34a1 |
T |
A |
13: 55,550,711 (GRCm39) |
|
probably null |
Het |
| Slfn10-ps |
T |
A |
11: 82,926,600 (GRCm39) |
|
noncoding transcript |
Het |
| Sohlh2 |
A |
G |
3: 55,115,163 (GRCm39) |
N383D |
probably damaging |
Het |
| Spag6 |
T |
A |
2: 18,715,302 (GRCm39) |
L27H |
probably damaging |
Het |
| Sptlc3 |
A |
G |
2: 139,388,475 (GRCm39) |
|
probably benign |
Het |
| St3gal4 |
T |
A |
9: 34,964,469 (GRCm39) |
K199* |
probably null |
Het |
| Stat5a |
T |
A |
11: 100,772,909 (GRCm39) |
D712E |
probably benign |
Het |
| Stmn2 |
A |
T |
3: 8,610,750 (GRCm39) |
D78V |
probably damaging |
Het |
| Stpg1 |
C |
T |
4: 135,233,777 (GRCm39) |
P20S |
possibly damaging |
Het |
| Taf2 |
A |
T |
15: 54,909,325 (GRCm39) |
V640E |
probably damaging |
Het |
| Tbce |
T |
C |
13: 14,172,747 (GRCm39) |
E501G |
probably benign |
Het |
| Tecpr2 |
A |
G |
12: 110,935,374 (GRCm39) |
S1398G |
probably damaging |
Het |
| Tenm4 |
T |
A |
7: 96,421,242 (GRCm39) |
Y598* |
probably null |
Het |
| Ticrr |
A |
G |
7: 79,327,088 (GRCm39) |
S599G |
probably damaging |
Het |
| Tnc |
A |
C |
4: 63,935,679 (GRCm39) |
V419G |
probably damaging |
Het |
| Trappc1 |
C |
A |
11: 69,216,402 (GRCm39) |
P110T |
probably benign |
Het |
| Trbv12-2 |
C |
T |
6: 41,095,993 (GRCm39) |
|
probably benign |
Het |
| Ttbk2 |
A |
T |
2: 120,576,264 (GRCm39) |
N835K |
possibly damaging |
Het |
| Tubgcp5 |
A |
G |
7: 55,450,432 (GRCm39) |
D181G |
probably damaging |
Het |
| Tut1 |
T |
C |
19: 8,932,891 (GRCm39) |
Y75H |
possibly damaging |
Het |
| Ulk2 |
C |
A |
11: 61,678,412 (GRCm39) |
C769F |
probably benign |
Het |
| Vdac1 |
T |
C |
11: 52,265,800 (GRCm39) |
|
probably benign |
Het |
| Vmn2r124 |
T |
C |
17: 18,284,486 (GRCm39) |
|
probably null |
Het |
| Wdr35 |
T |
C |
12: 9,045,625 (GRCm39) |
|
probably benign |
Het |
| Zdhhc7 |
T |
A |
8: 120,813,386 (GRCm39) |
E141V |
probably null |
Het |
| Zfp12 |
C |
A |
5: 143,230,978 (GRCm39) |
S435Y |
probably damaging |
Het |
| Zfp974 |
A |
T |
7: 27,626,819 (GRCm39) |
|
probably benign |
Het |
| Zfyve9 |
T |
A |
4: 108,538,166 (GRCm39) |
K1033N |
probably damaging |
Het |
| Zswim8 |
T |
A |
14: 20,772,013 (GRCm39) |
S1572T |
possibly damaging |
Het |
|
| Other mutations in Vps8 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00500:Vps8
|
APN |
16 |
21,261,084 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL00596:Vps8
|
APN |
16 |
21,267,162 (GRCm39) |
splice site |
probably benign |
|
|
IGL00985:Vps8
|
APN |
16 |
21,296,334 (GRCm39) |
splice site |
probably benign |
|
|
IGL01356:Vps8
|
APN |
16 |
21,336,107 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01375:Vps8
|
APN |
16 |
21,378,122 (GRCm39) |
nonsense |
probably null |
|
|
IGL01643:Vps8
|
APN |
16 |
21,336,972 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02159:Vps8
|
APN |
16 |
21,285,234 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL02214:Vps8
|
APN |
16 |
21,336,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02465:Vps8
|
APN |
16 |
21,340,653 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02651:Vps8
|
APN |
16 |
21,336,086 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03174:Vps8
|
APN |
16 |
21,285,213 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03337:Vps8
|
APN |
16 |
21,381,918 (GRCm39) |
missense |
probably benign |
|
|
IGL03383:Vps8
|
APN |
16 |
21,254,573 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03402:Vps8
|
APN |
16 |
21,267,148 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
empires
|
UTSW |
16 |
21,400,298 (GRCm39) |
nonsense |
probably null |
|
|
porky
|
UTSW |
16 |
21,279,988 (GRCm39) |
missense |
probably benign |
0.32 |
|
realm
|
UTSW |
16 |
21,363,986 (GRCm39) |
intron |
probably benign |
|
|
realms
|
UTSW |
16 |
21,262,938 (GRCm39) |
splice site |
probably null |
|
|
Reich
|
UTSW |
16 |
21,297,189 (GRCm39) |
missense |
probably benign |
0.29 |
|
reichen
|
UTSW |
16 |
21,325,575 (GRCm39) |
splice site |
probably benign |
|
|
IGL03052:Vps8
|
UTSW |
16 |
21,267,115 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4677001:Vps8
|
UTSW |
16 |
21,319,084 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0066:Vps8
|
UTSW |
16 |
21,296,273 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0066:Vps8
|
UTSW |
16 |
21,296,273 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0125:Vps8
|
UTSW |
16 |
21,288,904 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0137:Vps8
|
UTSW |
16 |
21,323,136 (GRCm39) |
splice site |
probably benign |
|
|
R0384:Vps8
|
UTSW |
16 |
21,325,575 (GRCm39) |
splice site |
probably benign |
|
|
R0492:Vps8
|
UTSW |
16 |
21,261,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0525:Vps8
|
UTSW |
16 |
21,358,859 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0531:Vps8
|
UTSW |
16 |
21,278,561 (GRCm39) |
intron |
probably benign |
|
|
R0605:Vps8
|
UTSW |
16 |
21,378,087 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0636:Vps8
|
UTSW |
16 |
21,253,683 (GRCm39) |
missense |
probably benign |
0.32 |
|
R0707:Vps8
|
UTSW |
16 |
21,261,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0840:Vps8
|
UTSW |
16 |
21,275,071 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1170:Vps8
|
UTSW |
16 |
21,278,570 (GRCm39) |
intron |
probably benign |
|
|
R1203:Vps8
|
UTSW |
16 |
21,330,307 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1482:Vps8
|
UTSW |
16 |
21,400,348 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1531:Vps8
|
UTSW |
16 |
21,285,226 (GRCm39) |
nonsense |
probably null |
|
|
R1642:Vps8
|
UTSW |
16 |
21,400,329 (GRCm39) |
missense |
probably benign |
|
|
R1956:Vps8
|
UTSW |
16 |
21,279,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2201:Vps8
|
UTSW |
16 |
21,395,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2287:Vps8
|
UTSW |
16 |
21,387,163 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2423:Vps8
|
UTSW |
16 |
21,378,087 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3151:Vps8
|
UTSW |
16 |
21,261,123 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3943:Vps8
|
UTSW |
16 |
21,288,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3944:Vps8
|
UTSW |
16 |
21,288,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4043:Vps8
|
UTSW |
16 |
21,345,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4302:Vps8
|
UTSW |
16 |
21,314,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4398:Vps8
|
UTSW |
16 |
21,323,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4477:Vps8
|
UTSW |
16 |
21,363,986 (GRCm39) |
intron |
probably benign |
|
|
R4478:Vps8
|
UTSW |
16 |
21,363,986 (GRCm39) |
intron |
probably benign |
|
|
R4479:Vps8
|
UTSW |
16 |
21,363,986 (GRCm39) |
intron |
probably benign |
|
|
R4480:Vps8
|
UTSW |
16 |
21,363,986 (GRCm39) |
intron |
probably benign |
|
|
R4571:Vps8
|
UTSW |
16 |
21,254,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4653:Vps8
|
UTSW |
16 |
21,318,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4664:Vps8
|
UTSW |
16 |
21,262,938 (GRCm39) |
splice site |
probably null |
|
|
R4713:Vps8
|
UTSW |
16 |
21,261,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4726:Vps8
|
UTSW |
16 |
21,267,154 (GRCm39) |
splice site |
probably null |
|
|
R4959:Vps8
|
UTSW |
16 |
21,278,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4973:Vps8
|
UTSW |
16 |
21,278,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4975:Vps8
|
UTSW |
16 |
21,285,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4992:Vps8
|
UTSW |
16 |
21,280,158 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R5144:Vps8
|
UTSW |
16 |
21,378,103 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5168:Vps8
|
UTSW |
16 |
21,351,849 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5168:Vps8
|
UTSW |
16 |
21,276,195 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5222:Vps8
|
UTSW |
16 |
21,400,298 (GRCm39) |
nonsense |
probably null |
|
|
R5231:Vps8
|
UTSW |
16 |
21,395,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5876:Vps8
|
UTSW |
16 |
21,280,189 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5963:Vps8
|
UTSW |
16 |
21,288,871 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R6010:Vps8
|
UTSW |
16 |
21,363,955 (GRCm39) |
intron |
probably benign |
|
|
R6023:Vps8
|
UTSW |
16 |
21,279,988 (GRCm39) |
missense |
probably benign |
0.32 |
|
R6173:Vps8
|
UTSW |
16 |
21,314,682 (GRCm39) |
splice site |
probably null |
|
|
R6185:Vps8
|
UTSW |
16 |
21,288,891 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6264:Vps8
|
UTSW |
16 |
21,378,099 (GRCm39) |
nonsense |
probably null |
|
|
R6409:Vps8
|
UTSW |
16 |
21,297,189 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6522:Vps8
|
UTSW |
16 |
21,261,129 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6528:Vps8
|
UTSW |
16 |
21,372,875 (GRCm39) |
nonsense |
probably null |
|
|
R6784:Vps8
|
UTSW |
16 |
21,381,957 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7040:Vps8
|
UTSW |
16 |
21,393,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7072:Vps8
|
UTSW |
16 |
21,400,329 (GRCm39) |
missense |
probably benign |
|
|
R7103:Vps8
|
UTSW |
16 |
21,345,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7149:Vps8
|
UTSW |
16 |
21,278,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7195:Vps8
|
UTSW |
16 |
21,275,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7206:Vps8
|
UTSW |
16 |
21,276,171 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7403:Vps8
|
UTSW |
16 |
21,253,722 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7782:Vps8
|
UTSW |
16 |
21,330,308 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7806:Vps8
|
UTSW |
16 |
21,278,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7846:Vps8
|
UTSW |
16 |
21,351,070 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7943:Vps8
|
UTSW |
16 |
21,296,622 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R8075:Vps8
|
UTSW |
16 |
21,340,644 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8190:Vps8
|
UTSW |
16 |
21,393,780 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8307:Vps8
|
UTSW |
16 |
21,314,652 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8483:Vps8
|
UTSW |
16 |
21,393,763 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8814:Vps8
|
UTSW |
16 |
21,395,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9064:Vps8
|
UTSW |
16 |
21,288,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9367:Vps8
|
UTSW |
16 |
21,340,668 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
R9404:Vps8
|
UTSW |
16 |
21,426,927 (GRCm39) |
missense |
probably benign |
0.12 |
|
R9544:Vps8
|
UTSW |
16 |
21,336,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9570:Vps8
|
UTSW |
16 |
21,462,953 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9634:Vps8
|
UTSW |
16 |
21,372,893 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9702:Vps8
|
UTSW |
16 |
21,462,883 (GRCm39) |
missense |
probably benign |
0.17 |
|
| Predicted Primers |
PCR Primer
(F):5'- CGTTTTGTTTTGTTGCTGTTGTTTTAAGCTC -3'
(R):5'- TCTACCCCTTGGTCTTACCTGCCAT -3'
Sequencing Primer
(F):5'- GCTGTTGTTTTAAGCTCAGCTATAC -3'
(R):5'- CTTAGTTGCCAGGAAACTGC -3'
|
| Posted On |
2013-05-09 |
Incidental Mutation