Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02895:Odam'

363373

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Odam

Ensembl Gene

ENSMUSG00000009580

Gene Name

odontogenic, ameloblast asssociated

Synonyms

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.094) question?

Stock #

IGL02895

Quality Score

Status

Chromosome

Chromosomal Location

87885029-87894174 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 87885864 bp

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Arginine at position 21 (Q21R)

Ref Sequence

ENSEMBL: ENSMUSP00000117898 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000113274] [ENSMUST00000129757]

Predicted Effect

probably benign
Transcript: ENSMUST00000113274
AA Change: Q21R

PolyPhen 2 Score 0.317 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000108899
Gene: ENSMUSG00000009580
AA Change: Q21R

Domain	Start	End	E-Value	Type
Pfam:ODAM	16	273	1.4e-128	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000129757
AA Change: Q21R

PolyPhen 2 Score 0.317 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000117898
Gene: ENSMUSG00000009580
AA Change: Q21R

Domain	Start	End	E-Value	Type
Pfam:ODAM	16	273	5.1e-132	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 19 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2410089E03Rik	A	G	15: 8,232,107		probably benign	Het
Ahctf1	C	T	1: 179,793,811	E130K	probably damaging	Het
Atf7ip	C	A	6: 136,560,688	S306R	probably damaging	Het
Cpd	A	G	11: 76,785,203	V1208A	probably benign	Het
Ctsl	C	T	13: 64,366,512	A195T	probably damaging	Het
Dennd2c	T	C	3: 103,137,203	Y367H	possibly damaging	Het
Endod1	T	A	9: 14,356,870	T440S	probably benign	Het
Gm12695	T	C	4: 96,723,949	R526G	probably damaging	Het
Ighv1-39	T	C	12: 114,914,682	T90A	probably damaging	Het
Kdm2a	G	A	19: 4,362,902	R19C	probably damaging	Het
Klra1	C	T	6: 130,375,240	E180K	possibly damaging	Het
Olfr1205	A	G	2: 88,831,642	Y175C	probably damaging	Het
Olfr145	G	A	9: 37,897,982	V193I	probably benign	Het
Plk1	A	G	7: 122,169,166	E504G	possibly damaging	Het
Rtl3	T	C	X: 106,839,544	I37M	possibly damaging	Het
Srebf2	A	G	15: 82,147,467	E22G	possibly damaging	Het
Tmem74b	A	G	2: 151,706,391	S13G	probably benign	Het
Utp14b	T	C	1: 78,664,607	V74A	possibly damaging	Het
Znrf3	T	C	11: 5,289,085	M93V	probably damaging	Het

Other mutations in Odam

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00970:Odam	APN	5	87886608	splice site	probably benign
IGL01339:Odam	APN	5	87885896	critical splice donor site	probably null
IGL01940:Odam	APN	5	87887333	missense	possibly damaging	0.87
IGL03051:Odam	APN	5	87892476	splice site	probably benign
IGL03118:Odam	APN	5	87885754	missense	unknown
BB005:Odam	UTSW	5	87887410	missense	possibly damaging	0.95
BB015:Odam	UTSW	5	87887410	missense	possibly damaging	0.95
R1816:Odam	UTSW	5	87889470	splice site	probably null
R2033:Odam	UTSW	5	87892419	missense	probably benign
R4965:Odam	UTSW	5	87890108	nonsense	probably null
R7257:Odam	UTSW	5	87887545	missense	probably benign	0.14
R7682:Odam	UTSW	5	87892428	missense	possibly damaging	0.71
R7928:Odam	UTSW	5	87887410	missense	possibly damaging	0.95
R8099:Odam	UTSW	5	87892440	missense	possibly damaging	0.52

Posted On

2015-12-18