Incidental Mutation 'IGL02895:Odam'
ID363373
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Odam
Ensembl Gene ENSMUSG00000009580
Gene Nameodontogenic, ameloblast asssociated
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.094) question?
Stock #IGL02895
Quality Score
Status
Chromosome5
Chromosomal Location87885029-87894174 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 87885864 bp
ZygosityHeterozygous
Amino Acid Change Glutamine to Arginine at position 21 (Q21R)
Ref Sequence ENSEMBL: ENSMUSP00000117898 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000113274] [ENSMUST00000129757]
Predicted Effect probably benign
Transcript: ENSMUST00000113274
AA Change: Q21R

PolyPhen 2 Score 0.317 (Sensitivity: 0.90; Specificity: 0.89)
SMART Domains Protein: ENSMUSP00000108899
Gene: ENSMUSG00000009580
AA Change: Q21R

DomainStartEndE-ValueType
Pfam:ODAM 16 273 1.4e-128 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000129757
AA Change: Q21R

PolyPhen 2 Score 0.317 (Sensitivity: 0.90; Specificity: 0.89)
SMART Domains Protein: ENSMUSP00000117898
Gene: ENSMUSG00000009580
AA Change: Q21R

DomainStartEndE-ValueType
Pfam:ODAM 16 273 5.1e-132 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 19 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2410089E03Rik A G 15: 8,232,107 probably benign Het
Ahctf1 C T 1: 179,793,811 E130K probably damaging Het
Atf7ip C A 6: 136,560,688 S306R probably damaging Het
Cpd A G 11: 76,785,203 V1208A probably benign Het
Ctsl C T 13: 64,366,512 A195T probably damaging Het
Dennd2c T C 3: 103,137,203 Y367H possibly damaging Het
Endod1 T A 9: 14,356,870 T440S probably benign Het
Gm12695 T C 4: 96,723,949 R526G probably damaging Het
Ighv1-39 T C 12: 114,914,682 T90A probably damaging Het
Kdm2a G A 19: 4,362,902 R19C probably damaging Het
Klra1 C T 6: 130,375,240 E180K possibly damaging Het
Olfr1205 A G 2: 88,831,642 Y175C probably damaging Het
Olfr145 G A 9: 37,897,982 V193I probably benign Het
Plk1 A G 7: 122,169,166 E504G possibly damaging Het
Rtl3 T C X: 106,839,544 I37M possibly damaging Het
Srebf2 A G 15: 82,147,467 E22G possibly damaging Het
Tmem74b A G 2: 151,706,391 S13G probably benign Het
Utp14b T C 1: 78,664,607 V74A possibly damaging Het
Znrf3 T C 11: 5,289,085 M93V probably damaging Het
Other mutations in Odam
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00970:Odam APN 5 87886608 splice site probably benign
IGL01339:Odam APN 5 87885896 critical splice donor site probably null
IGL01940:Odam APN 5 87887333 missense possibly damaging 0.87
IGL03051:Odam APN 5 87892476 splice site probably benign
IGL03118:Odam APN 5 87885754 missense unknown
BB005:Odam UTSW 5 87887410 missense possibly damaging 0.95
BB015:Odam UTSW 5 87887410 missense possibly damaging 0.95
R1816:Odam UTSW 5 87889470 splice site probably null
R2033:Odam UTSW 5 87892419 missense probably benign
R4965:Odam UTSW 5 87890108 nonsense probably null
R7257:Odam UTSW 5 87887545 missense probably benign 0.14
R7682:Odam UTSW 5 87892428 missense possibly damaging 0.71
R7928:Odam UTSW 5 87887410 missense possibly damaging 0.95
R8099:Odam UTSW 5 87892440 missense possibly damaging 0.52
Posted On2015-12-18