Incidental Mutation 'IGL02897:Vmn1r63'
ID363430
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r63
Ensembl Gene ENSMUSG00000058631
Gene Namevomeronasal 1 receptor 63
SynonymsV1R1, V1rd1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.070) question?
Stock #IGL02897
Quality Score
Status
Chromosome7
Chromosomal Location5802345-5805445 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 5802745 bp
ZygosityHeterozygous
Amino Acid Change Valine to Alanine at position 296 (V296A)
Ref Sequence ENSEMBL: ENSMUSP00000074593 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000075085]
Predicted Effect possibly damaging
Transcript: ENSMUST00000075085
AA Change: V296A

PolyPhen 2 Score 0.511 (Sensitivity: 0.88; Specificity: 0.90)
SMART Domains Protein: ENSMUSP00000074593
Gene: ENSMUSG00000058631
AA Change: V296A

DomainStartEndE-ValueType
Pfam:TAS2R 1 294 3.1e-10 PFAM
Pfam:V1R 31 297 2.2e-17 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000207420
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 35 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700093K21Rik T A 11: 23,517,308 E108D probably benign Het
Abca7 T C 10: 80,001,592 F437L probably damaging Het
Abi2 T C 1: 60,448,194 V134A probably damaging Het
Ablim2 T C 5: 35,833,126 I75T probably damaging Het
Aldh1a3 A G 7: 66,427,327 V29A probably benign Het
Bptf T C 11: 107,047,121 K2715E probably damaging Het
Cd163 A T 6: 124,325,527 S1017C probably damaging Het
Cdc14b T C 13: 64,247,253 I76V probably benign Het
Cers6 T A 2: 68,934,533 C63* probably null Het
Chd9 T C 8: 90,933,868 probably benign Het
Col19a1 T C 1: 24,534,098 N198D unknown Het
Cse1l T C 2: 166,919,708 C61R possibly damaging Het
Cubn T C 2: 13,318,312 T2815A possibly damaging Het
Cyp19a1 G T 9: 54,166,911 T453K possibly damaging Het
Dlg1 G T 16: 31,771,856 probably null Het
Dpp7 T C 2: 25,353,672 Y339C probably damaging Het
Dtl T C 1: 191,541,544 probably benign Het
Gm5591 T C 7: 38,520,042 E469G probably damaging Het
Ing3 T A 6: 21,969,326 V202E probably benign Het
Inpp5j A G 11: 3,500,619 L578P probably damaging Het
Irak4 A G 15: 94,553,991 N155S probably benign Het
Kif2b A T 11: 91,576,219 S413T probably damaging Het
L3mbtl1 A T 2: 162,965,772 Y490F probably damaging Het
Med17 T G 9: 15,267,534 D447A probably damaging Het
Med26 T C 8: 72,496,521 T245A probably benign Het
Nlrc3 A T 16: 3,964,074 S490R possibly damaging Het
Nme5 A G 18: 34,569,903 probably benign Het
Olfr611 T C 7: 103,518,130 R85G probably benign Het
Rnf10 G T 5: 115,248,641 Q530K probably benign Het
Robo3 A T 9: 37,427,502 Y281* probably null Het
Sclt1 T C 3: 41,675,387 I330V probably benign Het
Smim14 A T 5: 65,450,396 probably benign Het
Trank1 T G 9: 111,367,517 H1536Q probably damaging Het
Tspan18 A G 2: 93,220,173 L35P possibly damaging Het
Ubr4 G A 4: 139,472,508 V4568M probably damaging Het
Other mutations in Vmn1r63
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02465:Vmn1r63 APN 7 5803039 missense probably damaging 1.00
IGL03032:Vmn1r63 APN 7 5803351 missense probably benign 0.18
IGL03190:Vmn1r63 APN 7 5803111 missense probably benign 0.00
R0118:Vmn1r63 UTSW 7 5802839 missense probably benign 0.00
R0227:Vmn1r63 UTSW 7 5802742 nonsense probably null
R0323:Vmn1r63 UTSW 7 5803336 missense probably benign 0.03
R0610:Vmn1r63 UTSW 7 5803064 missense possibly damaging 0.89
R0630:Vmn1r63 UTSW 7 5803264 missense probably damaging 1.00
R0689:Vmn1r63 UTSW 7 5803610 missense probably benign 0.24
R1916:Vmn1r63 UTSW 7 5803226 missense probably damaging 0.96
R1993:Vmn1r63 UTSW 7 5803255 missense probably benign 0.12
R1994:Vmn1r63 UTSW 7 5803255 missense probably benign 0.12
R2209:Vmn1r63 UTSW 7 5803213 missense probably damaging 0.99
R3787:Vmn1r63 UTSW 7 5802752 missense probably benign
R4156:Vmn1r63 UTSW 7 5803532 missense possibly damaging 0.89
R4702:Vmn1r63 UTSW 7 5803517 missense possibly damaging 0.68
R4728:Vmn1r63 UTSW 7 5803363 missense probably damaging 0.99
R5410:Vmn1r63 UTSW 7 5803190 missense possibly damaging 0.55
R5796:Vmn1r63 UTSW 7 5803141 missense probably benign
R6580:Vmn1r63 UTSW 7 5802914 missense probably benign 0.02
R6723:Vmn1r63 UTSW 7 5802949 missense probably damaging 0.96
R7418:Vmn1r63 UTSW 7 5803555 missense possibly damaging 0.94
R7476:Vmn1r63 UTSW 7 5803001 missense probably benign 0.13
R7769:Vmn1r63 UTSW 7 5803370 missense probably damaging 1.00
X0027:Vmn1r63 UTSW 7 5802931 missense probably damaging 1.00
Posted On2015-12-18