Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02903:Gm13089'

363684

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm13089

Ensembl Gene

ENSMUSG00000070617

Gene Name

predicted gene 13089

Synonyms

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.060) question?

Stock #

IGL02903

Quality Score

Status

Chromosome

Chromosomal Location

143696500-143702711 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 143699166 bp

Zygosity

Heterozygous

Amino Acid Change

Methionine to Lysine at position 69 (M69K)

Ref Sequence

ENSEMBL: ENSMUSP00000073224 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000073532]

Predicted Effect

probably benign
Transcript: ENSMUST00000073532
AA Change: M69K

PolyPhen 2 Score 0.035 (Sensitivity: 0.94; Specificity: 0.82)

SMART Domains

Protein: ENSMUSP00000073224
Gene: ENSMUSG00000070617
AA Change: M69K

Domain	Start	End	E-Value	Type
low complexity region	204	216	N/A	INTRINSIC
low complexity region	331	343	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 37 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2410089E03Rik	G	T	15: 8,269,778	R3150M	unknown	Het
2410089E03Rik	G	T	15: 8,269,779	R3150S	unknown	Het
4931417E11Rik	A	G	6: 73,469,120	Y149H	probably damaging	Het
Alox5	T	G	6: 116,420,335	N296T	probably damaging	Het
Anks6	C	T	4: 47,045,004	E301K	probably damaging	Het
Astn1	A	G	1: 158,688,550	S1237G	probably damaging	Het
Atf6	G	A	1: 170,799,714	P394S	probably benign	Het
Atp4a	G	A	7: 30,715,919	M321I	probably benign	Het
C4bp	G	A	1: 130,655,985	T82I	probably damaging	Het
Cask	A	T	X: 13,552,447		probably benign	Het
Cenpf	A	T	1: 189,646,876	S2906T	probably damaging	Het
Cfl1	T	C	19: 5,492,800	F103L	probably benign	Het
Chrnb3	A	T	8: 27,386,806	T83S	probably damaging	Het
Cmtr2	A	G	8: 110,222,878	T607A	probably benign	Het
Cts7	A	T	13: 61,356,626		probably benign	Het
Dgkz	A	T	2: 91,939,962	Y514N	possibly damaging	Het
Dmrtc1b	T	A	X: 102,713,567	L206Q	probably benign	Het
Dus3l	C	T	17: 56,768,363	L397F	probably damaging	Het
Fam159b	T	A	13: 104,863,610	Y35F	probably benign	Het
Gm6356	C	T	14: 6,973,735	G27E	probably damaging	Het
Hkdc1	C	T	10: 62,400,191		probably null	Het
Kcmf1	A	T	6: 72,858,883	V21E	possibly damaging	Het
Kcnh4	T	A	11: 100,757,654	T75S	possibly damaging	Het
Lemd2	A	G	17: 27,193,210		probably benign	Het
Magee1	G	T	X: 105,123,339	R910L	probably damaging	Het
Mcm3ap	T	C	10: 76,471,258		probably benign	Het
Mfsd4b3	T	A	10: 39,947,643	E207V	possibly damaging	Het
Olfr1354	A	G	10: 78,917,416	D192G	probably damaging	Het
Olfr697	A	G	7: 106,741,710	S75P	probably damaging	Het
Pappa	T	C	4: 65,261,980	V1026A	probably damaging	Het
Paxip1	A	G	5: 27,748,872	L942P	probably damaging	Het
Ppp1r12b	A	T	1: 134,955,649	L45Q	probably benign	Het
Ptprq	T	C	10: 107,666,586	T824A	possibly damaging	Het
Rfwd3	T	C	8: 111,278,229	T574A	probably benign	Het
Rsbn1	T	C	3: 103,928,569	S308P	probably damaging	Het
Smr2	A	T	5: 88,108,630	I56F	probably benign	Het
Wdfy4	C	T	14: 33,109,650	R873H	probably damaging	Het

Other mutations in Gm13089

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01720:Gm13089	APN	4	143696840	utr 3 prime	probably benign
IGL02087:Gm13089	APN	4	143697074	missense	probably damaging	0.96
IGL02296:Gm13089	APN	4	143698481	nonsense	probably null
IGL02902:Gm13089	APN	4	143698343	missense	probably damaging	1.00
IGL02962:Gm13089	APN	4	143697340	missense	probably benign	0.28
IGL03351:Gm13089	APN	4	143697088	missense	possibly damaging	0.80
R0122:Gm13089	UTSW	4	143698404	missense	probably benign	0.44
R0533:Gm13089	UTSW	4	143698020	nonsense	probably null
R0609:Gm13089	UTSW	4	143698503	missense	probably benign	0.00
R0743:Gm13089	UTSW	4	143698564	missense	probably damaging	0.97
R0744:Gm13089	UTSW	4	143698486	missense	probably benign	0.19
R0833:Gm13089	UTSW	4	143698486	missense	probably benign	0.19
R1052:Gm13089	UTSW	4	143696907	missense	possibly damaging	0.81
R1690:Gm13089	UTSW	4	143698123	missense	probably benign	0.03
R1764:Gm13089	UTSW	4	143698270	missense	probably benign	0.14
R1896:Gm13089	UTSW	4	143698144	missense	probably benign	0.11
R2084:Gm13089	UTSW	4	143699350	missense	probably damaging	1.00
R2178:Gm13089	UTSW	4	143698042	missense	possibly damaging	0.95
R2888:Gm13089	UTSW	4	143696890	missense	probably benign	0.00
R3759:Gm13089	UTSW	4	143697151	missense	probably damaging	1.00
R4193:Gm13089	UTSW	4	143698333	missense	probably damaging	1.00
R4380:Gm13089	UTSW	4	143698286	missense	probably benign	0.21
R4385:Gm13089	UTSW	4	143698014	critical splice donor site	probably null
R4513:Gm13089	UTSW	4	143698148	missense	probably benign	0.00
R4647:Gm13089	UTSW	4	143699344	missense	probably benign	0.00
R4920:Gm13089	UTSW	4	143699283	missense	probably benign	0.05
R4994:Gm13089	UTSW	4	143698369	missense	possibly damaging	0.94
R5197:Gm13089	UTSW	4	143698062	missense	possibly damaging	0.86
R6005:Gm13089	UTSW	4	143698432	missense	probably benign	0.00
R6073:Gm13089	UTSW	4	143698268	missense	probably damaging	0.99
R6197:Gm13089	UTSW	4	143697316	missense	possibly damaging	0.90
R6264:Gm13089	UTSW	4	143699152	missense	possibly damaging	0.50
R6821:Gm13089	UTSW	4	143699304	nonsense	probably null
R6923:Gm13089	UTSW	4	143699106	missense	probably benign	0.06
R7034:Gm13089	UTSW	4	143697328	missense	probably damaging	1.00
R7140:Gm13089	UTSW	4	143698432	missense	probably benign	0.01
R7298:Gm13089	UTSW	4	143698505	missense	probably benign	0.23
R7529:Gm13089	UTSW	4	143702674
R7766:Gm13089	UTSW	4	143699239	missense	probably damaging	0.98
R7774:Gm13089	UTSW	4	143697106	missense	possibly damaging	0.89
R7816:Gm13089	UTSW	4	143698194	missense	probably benign	0.00
R8137:Gm13089	UTSW	4	143699265	missense	probably damaging	1.00
Z1088:Gm13089	UTSW	4	143698080	missense	probably benign
Z1176:Gm13089	UTSW	4	143696945	missense	probably benign	0.00

Posted On

2015-12-18