Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02936:Vmn1r15'

364299

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r15

Ensembl Gene

ENSMUSG00000115199

Gene Name

vomeronasal 1 receptor 15

Synonyms

V1rc6

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.145) question?

Stock #

IGL02936

Quality Score

Status

Chromosome

Chromosomal Location

57235134-57236033 bp(+) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

A to T at 57235803 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Stop codon at position 224 (K224*)

Ref Sequence

ENSEMBL: ENSMUSP00000154252 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000071304] [ENSMUST00000228297]

AlphaFold

Q14C10

Predicted Effect

probably null
Transcript: ENSMUST00000071304
AA Change: K224*

SMART Domains

Protein: ENSMUSP00000071272
Gene: ENSMUSG00000115236
AA Change: K224*

Domain	Start	End	E-Value	Type
Pfam:V1R	28	293	4.5e-56	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000228297
AA Change: K224*

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 41 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700017B05Rik	G	A	9: 57,165,687 (GRCm39)	T229I	possibly damaging	Het
Acad11	T	C	9: 103,990,711 (GRCm39)	S439P	probably benign	Het
Acer2	A	T	4: 86,818,796 (GRCm39)	N148I	possibly damaging	Het
Adgre1	A	G	17: 57,785,833 (GRCm39)	I860V	probably benign	Het
Asb2	A	G	12: 103,302,173 (GRCm39)	I125T	probably benign	Het
Atp13a2	G	T	4: 140,729,260 (GRCm39)	L614F	probably benign	Het
Car7	A	G	8: 105,274,854 (GRCm39)	T132A	possibly damaging	Het
Cfap221	T	C	1: 119,912,482 (GRCm39)	D135G	probably damaging	Het
Crtc3	A	G	7: 80,239,511 (GRCm39)	F614L	probably damaging	Het
Csn3	T	G	5: 88,077,992 (GRCm39)	I166S	possibly damaging	Het
Dna2	T	G	10: 62,792,879 (GRCm39)	L298R	probably damaging	Het
Ece1	T	C	4: 137,673,612 (GRCm39)	S387P	probably benign	Het
Fbxo28	C	T	1: 182,169,093 (GRCm39)	G15D	unknown	Het
Fbxw24	A	T	9: 109,454,026 (GRCm39)		probably null	Het
Foxd3	T	A	4: 99,545,052 (GRCm39)	V64E	probably benign	Het
Galnt7	A	C	8: 58,037,248 (GRCm39)	V47G	probably benign	Het
Gcc2	A	T	10: 58,131,962 (GRCm39)	L1453F	probably damaging	Het
Gcnt4	G	A	13: 97,082,919 (GRCm39)	V72I	probably benign	Het
Gm10269	A	C	18: 20,816,010 (GRCm39)		probably null	Het
Hmcn1	T	G	1: 150,573,273 (GRCm39)	Q2125H	probably damaging	Het
Iho1	T	C	9: 108,289,702 (GRCm39)	I173M	possibly damaging	Het
Llcfc1	T	A	6: 41,661,593 (GRCm39)	S48T	probably benign	Het
Met	G	T	6: 17,553,396 (GRCm39)	V1061F	probably damaging	Het
Mthfd2	G	A	6: 83,288,342 (GRCm39)	H138Y	probably damaging	Het
Mtus1	A	T	8: 41,452,554 (GRCm39)	D1041E	possibly damaging	Het
Mug2	G	A	6: 122,058,346 (GRCm39)		probably null	Het
Nos3	C	T	5: 24,585,991 (GRCm39)	T878I	probably damaging	Het
Or4c15	A	G	2: 88,760,128 (GRCm39)	M177T	probably benign	Het
Or52b1	A	T	7: 104,979,212 (GRCm39)	Y62*	probably null	Het
Pbrm1	T	A	14: 30,783,470 (GRCm39)	V497D	probably damaging	Het
Plcd1	T	C	9: 118,903,267 (GRCm39)	E471G	probably damaging	Het
Poc1a	A	G	9: 106,162,226 (GRCm39)	T84A	probably damaging	Het
Ppm1f	A	G	16: 16,733,100 (GRCm39)	H209R	probably damaging	Het
Rccd1	T	A	7: 79,966,794 (GRCm39)	K329N	probably damaging	Het
Serpinb9g	A	T	13: 33,678,865 (GRCm39)	N245I	possibly damaging	Het
Slc22a26	A	C	19: 7,768,470 (GRCm39)	F196V	probably damaging	Het
Tial1	G	A	7: 128,044,387 (GRCm39)		probably benign	Het
Trpa1	A	T	1: 14,946,193 (GRCm39)		probably null	Het
Wdr72	A	T	9: 74,059,862 (GRCm39)	D424V	probably damaging	Het
Wt1	A	G	2: 104,999,384 (GRCm39)	K308E	probably damaging	Het
Zwint	T	C	10: 72,492,956 (GRCm39)	S193P	probably damaging	Het

Other mutations in Vmn1r15

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01645:Vmn1r15	APN	6	57,235,547 (GRCm39)	nonsense	probably null
IGL02326:Vmn1r15	APN	6	57,235,255 (GRCm39)	missense	probably benign	0.02
IGL02431:Vmn1r15	APN	6	57,235,888 (GRCm39)	missense	possibly damaging	0.94
IGL02990:Vmn1r15	APN	6	57,235,593 (GRCm39)	missense	probably benign	0.14
IGL03177:Vmn1r15	APN	6	57,235,458 (GRCm39)	missense	probably benign	0.27
IGL03382:Vmn1r15	APN	6	57,235,555 (GRCm39)	missense	probably benign	0.04
R0531:Vmn1r15	UTSW	6	57,235,236 (GRCm39)	missense	probably benign	0.10
R1858:Vmn1r15	UTSW	6	57,235,616 (GRCm39)	missense	probably benign	0.13
R2010:Vmn1r15	UTSW	6	57,235,269 (GRCm39)	missense	probably benign	0.02
R2055:Vmn1r15	UTSW	6	57,235,729 (GRCm39)	missense	possibly damaging	0.90
R2291:Vmn1r15	UTSW	6	57,235,677 (GRCm39)	missense	possibly damaging	0.93
R3697:Vmn1r15	UTSW	6	57,235,321 (GRCm39)	missense	possibly damaging	0.63
R5161:Vmn1r15	UTSW	6	57,235,497 (GRCm39)	missense	probably benign	0.00
R5884:Vmn1r15	UTSW	6	57,235,993 (GRCm39)	missense	probably damaging	0.99
R7287:Vmn1r15	UTSW	6	57,235,201 (GRCm39)	missense	possibly damaging	0.63
R7376:Vmn1r15	UTSW	6	57,235,342 (GRCm39)	missense	probably benign	0.11
R7773:Vmn1r15	UTSW	6	57,235,644 (GRCm39)	missense	probably benign	0.05
R7980:Vmn1r15	UTSW	6	57,235,399 (GRCm39)	missense	probably damaging	1.00
R8309:Vmn1r15	UTSW	6	57,235,635 (GRCm39)	missense	probably benign	0.01
R8753:Vmn1r15	UTSW	6	57,235,895 (GRCm39)	missense	probably benign	0.01
R8765:Vmn1r15	UTSW	6	57,235,585 (GRCm39)	missense	probably benign	0.01
R8812:Vmn1r15	UTSW	6	57,235,123 (GRCm39)	start gained	probably benign

Posted On

2015-12-18