Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02941:Gm4953'

364487

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm4953

Ensembl Gene

ENSMUSG00000061992

Gene Name

predicted pseudogene 4953

Synonyms

Accession Numbers

Essential gene?

Probably essential (E-score: 0.825) question?

Stock #

IGL02941

Quality Score

Status

Chromosome

Chromosomal Location

158995730-158996212 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

C to T at 158995963 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000077309

SMART Domains

Protein: ENSMUSP00000076538
Gene: ENSMUSG00000061992

Domain	Start	End	E-Value	Type
Pfam:Mt_ATP-synt_D	3	160	3.3e-65	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000195279

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 41 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4933405O20Rik	G	A	7: 50,249,284 (GRCm39)	R106Q	probably damaging	Het
Amhr2	T	C	15: 102,355,724 (GRCm39)	V223A	probably damaging	Het
Aqr	T	A	2: 113,943,835 (GRCm39)	H1101L	probably damaging	Het
Arnt	T	A	3: 95,367,681 (GRCm39)		probably benign	Het
Cacnb2	G	A	2: 14,963,640 (GRCm39)	V85I	probably benign	Het
Cast	A	T	13: 74,848,806 (GRCm39)	D727E	probably damaging	Het
Ccdc134	C	T	15: 82,025,151 (GRCm39)	R217W	probably damaging	Het
Cemip2	G	A	19: 21,801,207 (GRCm39)	D775N	possibly damaging	Het
Col5a3	A	G	9: 20,715,962 (GRCm39)	S360P	unknown	Het
Cyp4f16	T	C	17: 32,756,061 (GRCm39)	I30T	possibly damaging	Het
Dop1b	T	C	16: 93,552,361 (GRCm39)	F267L	probably benign	Het
Fbxo3	A	G	2: 103,880,639 (GRCm39)	T250A	probably damaging	Het
Gm9242	T	C	16: 97,292,279 (GRCm39)		probably benign	Het
Gsr	G	A	8: 34,179,453 (GRCm39)	V354I	probably damaging	Het
H2bc21	A	G	3: 96,128,732 (GRCm39)	Y84C	possibly damaging	Het
Hecw1	T	A	13: 14,552,311 (GRCm39)	D96V	probably damaging	Het
Il18r1	A	G	1: 40,537,711 (GRCm39)	Y492C	probably damaging	Het
Itgb5	T	G	16: 33,764,465 (GRCm39)		probably benign	Het
Lars2	T	G	9: 123,288,650 (GRCm39)	L832R	probably damaging	Het
Ms4a6c	A	G	19: 11,448,466 (GRCm39)		probably benign	Het
Nrxn1	T	C	17: 90,515,811 (GRCm39)	S1227G	probably damaging	Het
Or1j11	T	C	2: 36,312,132 (GRCm39)	C241R	probably damaging	Het
Or2c1	T	C	16: 3,657,680 (GRCm39)	V281A	possibly damaging	Het
Or52r1c	A	G	7: 102,735,528 (GRCm39)	T263A	probably benign	Het
Pcdh17	A	G	14: 84,685,747 (GRCm39)	Y738C	probably damaging	Het
Pcsk5	C	A	19: 17,424,865 (GRCm39)	C1646F	probably damaging	Het
Pirb	A	G	7: 3,720,377 (GRCm39)	V332A	probably damaging	Het
Pkd1l2	G	A	8: 117,792,484 (GRCm39)	T436I	probably benign	Het
Polrmt	A	T	10: 79,573,092 (GRCm39)		probably benign	Het
Saxo1	G	T	4: 86,363,821 (GRCm39)	R221S	probably damaging	Het
Specc1l	A	G	10: 75,077,022 (GRCm39)	I93V	probably benign	Het
St8sia2	T	A	7: 73,626,397 (GRCm39)		probably benign	Het
Tep1	A	T	14: 51,103,494 (GRCm39)	N265K	probably damaging	Het
Thbd	A	T	2: 148,248,954 (GRCm39)	Y305N	probably damaging	Het
Tmem120a	T	C	5: 135,764,605 (GRCm39)	T325A	probably damaging	Het
Vill	G	A	9: 118,895,955 (GRCm39)		probably benign	Het
Wdr35	A	G	12: 9,077,507 (GRCm39)	D1060G	probably damaging	Het
Xrn2	T	A	2: 146,868,444 (GRCm39)	F166I	probably damaging	Het
Zc3h7a	T	G	16: 10,976,458 (GRCm39)		probably null	Het
Zdhhc13	G	A	7: 48,466,886 (GRCm39)		probably benign	Het
Zfp808	T	A	13: 62,320,944 (GRCm39)	N724K	possibly damaging	Het

Other mutations in Gm4953

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL02562:Gm4953	APN	1	158,996,077 (GRCm39)	unclassified	noncoding transcript
R1976:Gm4953	UTSW	1	158,995,923 (GRCm39)	unclassified	noncoding transcript
R4802:Gm4953	UTSW	1	158,995,988 (GRCm39)	unclassified	noncoding transcript
R4910:Gm4953	UTSW	1	158,995,929 (GRCm39)	unclassified	noncoding transcript
R4911:Gm4953	UTSW	1	158,995,929 (GRCm39)	unclassified	noncoding transcript

Posted On

2015-12-18