Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02948:Atm'

364857

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Atm

Ensembl Gene

ENSMUSG00000034218

Gene Name

ataxia telangiectasia mutated

Synonyms

C030026E19Rik

Accession Numbers

Essential gene?

Probably essential (E-score: 0.928) question?

Stock #

IGL02948

Quality Score

Status

Chromosome

Chromosomal Location

53439149-53536740 bp(-) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

G to A at 53453440 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000156344 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000118282] [ENSMUST00000232179]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000118282

SMART Domains

Protein: ENSMUSP00000113388
Gene: ENSMUSG00000034218

Domain	Start	End	E-Value	Type
TAN	1	166	5.07e-68	SMART
low complexity region	431	445	N/A	INTRINSIC
low complexity region	830	846	N/A	INTRINSIC
low complexity region	929	940	N/A	INTRINSIC
SCOP:d1gw5a_	1039	1568	2e-4	SMART
coiled coil region	1615	1644	N/A	INTRINSIC
low complexity region	1650	1662	N/A	INTRINSIC
Pfam:FAT	2102	2499	4.4e-50	PFAM
low complexity region	2587	2599	N/A	INTRINSIC
PI3Kc	2723	3026	1.11e-117	SMART
FATC	3034	3066	3.71e-11	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000132249

SMART Domains

Protein: ENSMUSP00000118199
Gene: ENSMUSG00000034218

Domain	Start	End	E-Value	Type
PI3Kc	68	201	5.38e-2	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000232179

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
PHENOTYPE: Homozygotes for null mutations may exhibit locomotor abnormalities, motor learning deficits, growth retardation, sterility due to meiotic arrest, and susceptibility to thymic lymphomas. Mice homozygous for a kinase dead allele exhibit early embryonic lethality associated with genetic instability. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 54 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aass	A	T	6: 23,094,319 (GRCm38)		probably benign	Het
Ano3	A	T	2: 110,697,018 (GRCm38)		probably benign	Het
Arpp21	T	C	9: 112,176,200 (GRCm38)	Y193C	probably damaging	Het
Ceacam13	C	T	7: 18,011,063 (GRCm38)		probably benign	Het
Cenpi	T	A	X: 134,349,268 (GRCm38)	C599S	possibly damaging	Het
Clec7a	A	C	6: 129,465,478 (GRCm38)	D195E	possibly damaging	Het
Cnksr1	T	C	4: 134,235,106 (GRCm38)		probably null	Het
Cntn1	A	G	15: 92,246,010 (GRCm38)	T285A	probably benign	Het
Dusp4	G	T	8: 34,818,572 (GRCm38)	G329V	probably damaging	Het
Emb	C	A	13: 117,273,066 (GRCm38)		probably benign	Het
Esyt1	A	T	10: 128,519,171 (GRCm38)	S496T	probably damaging	Het
Evpl	T	C	11: 116,221,822 (GRCm38)	T1681A	probably damaging	Het
Fam131b	A	C	6: 42,320,992 (GRCm38)		probably benign	Het
Fam162b	T	C	10: 51,587,296 (GRCm38)	M92V	probably damaging	Het
Fbxw2	T	C	2: 34,805,711 (GRCm38)	*455W	probably null	Het
Gm12886	A	G	4: 121,423,037 (GRCm38)	L14P	unknown	Het
Gpc4	A	T	X: 52,074,301 (GRCm38)	V235E	probably damaging	Het
Gss	A	G	2: 155,577,621 (GRCm38)	L170P	probably damaging	Het
Hbs1l	C	T	10: 21,341,711 (GRCm38)		probably benign	Het
Hhatl	T	C	9: 121,789,791 (GRCm38)	M92V	probably benign	Het
Hhla1	A	T	15: 65,942,693 (GRCm38)	L194H	probably damaging	Het
Hivep2	C	A	10: 14,129,013 (GRCm38)	R452S	probably benign	Het
Homer2	C	A	7: 81,649,645 (GRCm38)	W24L	probably damaging	Het
Lhcgr	A	T	17: 88,742,622 (GRCm38)	L492H	probably damaging	Het
Lrba	C	A	3: 86,310,384 (GRCm38)		probably null	Het
Lrp2	G	T	2: 69,487,837 (GRCm38)	P2090Q	probably damaging	Het
Lyl1	C	T	8: 84,702,671 (GRCm38)	P3L	possibly damaging	Het
Madd	T	A	2: 91,142,827 (GRCm38)	M1497L	probably benign	Het
Naprt	C	T	15: 75,892,357 (GRCm38)	R336Q	probably damaging	Het
Nars	A	G	18: 64,505,195 (GRCm38)	C266R	possibly damaging	Het
Olfr1420	T	A	19: 11,896,781 (GRCm38)	Y253*	probably null	Het
Olfr175-ps1	T	A	16: 58,824,088 (GRCm38)	Q207L	probably benign	Het
Pard3	A	T	8: 127,306,494 (GRCm38)	T190S	probably benign	Het
Pstpip2	A	G	18: 77,854,807 (GRCm38)	N86S	probably benign	Het
Ptgfrn	T	C	3: 101,072,819 (GRCm38)	T402A	probably benign	Het
Rnf130	T	C	11: 50,052,771 (GRCm38)		probably benign	Het
Ropn1l	T	C	15: 31,451,179 (GRCm38)	D53G	possibly damaging	Het
Rps6ka2	G	A	17: 7,254,450 (GRCm38)		probably null	Het
Rtn2	T	C	7: 19,293,111 (GRCm38)	S17P	probably damaging	Het
Shank2	T	C	7: 144,409,636 (GRCm38)	V327A	probably benign	Het
Slc22a16	T	G	10: 40,573,962 (GRCm38)	Y131*	probably null	Het
Slc28a2	T	A	2: 122,457,977 (GRCm38)	M583K	possibly damaging	Het
Slco1a6	G	T	6: 142,133,235 (GRCm38)		probably null	Het
Slfn8	T	A	11: 83,003,252 (GRCm38)	I854F	probably damaging	Het
Strip1	T	C	3: 107,613,266 (GRCm38)	R823G	probably benign	Het
Stxbp2	A	T	8: 3,641,971 (GRCm38)	I538F	probably benign	Het
Tcl1b5	C	T	12: 105,179,014 (GRCm38)	T79M	probably benign	Het
Tmem104	G	T	11: 115,197,296 (GRCm38)	A36S	probably damaging	Het
Trim55	T	A	3: 19,670,952 (GRCm38)	L211Q	probably damaging	Het
Trim80	T	C	11: 115,441,593 (GRCm38)	W204R	possibly damaging	Het
Ttbk1	G	A	17: 46,446,330 (GRCm38)	T1126I	probably benign	Het
Ubqln2	C	T	X: 153,499,696 (GRCm38)	Q415*	probably null	Het
Unc13a	C	T	8: 71,650,549 (GRCm38)	R931H	possibly damaging	Het
Utp4	T	A	8: 106,894,641 (GRCm38)	S17T	probably benign	Het

Other mutations in Atm

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00090:Atm	APN	9	53,524,443 (GRCm38)	missense	probably damaging	1.00
IGL00466:Atm	APN	9	53,499,112 (GRCm38)	splice site	probably benign
IGL00567:Atm	APN	9	53,503,116 (GRCm38)	nonsense	probably null
IGL00702:Atm	APN	9	53,511,831 (GRCm38)	missense	probably benign	0.02
IGL00743:Atm	APN	9	53,513,116 (GRCm38)	missense	probably benign	0.00
IGL00771:Atm	APN	9	53,493,054 (GRCm38)	missense	probably benign	0.01
IGL00773:Atm	APN	9	53,522,144 (GRCm38)	missense	probably benign	0.00
IGL00819:Atm	APN	9	53,518,531 (GRCm38)	missense	probably damaging	1.00
IGL00864:Atm	APN	9	53,533,933 (GRCm38)	missense	probably damaging	0.99
IGL00985:Atm	APN	9	53,459,816 (GRCm38)	missense	probably damaging	0.98
IGL01109:Atm	APN	9	53,490,293 (GRCm38)	missense	probably damaging	1.00
IGL01120:Atm	APN	9	53,461,122 (GRCm38)	critical splice acceptor site	probably null
IGL01369:Atm	APN	9	53,515,317 (GRCm38)	missense	probably benign
IGL01374:Atm	APN	9	53,531,724 (GRCm38)	missense	possibly damaging	0.58
IGL01406:Atm	APN	9	53,439,746 (GRCm38)	makesense	probably null
IGL01409:Atm	APN	9	53,499,171 (GRCm38)	missense	probably benign	0.01
IGL01434:Atm	APN	9	53,507,807 (GRCm38)	missense	probably benign	0.04
IGL01486:Atm	APN	9	53,510,213 (GRCm38)	missense	probably benign
IGL01583:Atm	APN	9	53,484,247 (GRCm38)	splice site	probably benign
IGL01861:Atm	APN	9	53,494,612 (GRCm38)	missense	probably null	0.89
IGL01865:Atm	APN	9	53,461,002 (GRCm38)	missense	probably damaging	1.00
IGL02026:Atm	APN	9	53,442,417 (GRCm38)	splice site	probably null
IGL02072:Atm	APN	9	53,459,796 (GRCm38)	missense	probably benign	0.01
IGL02075:Atm	APN	9	53,527,237 (GRCm38)	missense	probably damaging	1.00
IGL02127:Atm	APN	9	53,487,983 (GRCm38)	missense	probably damaging	1.00
IGL02175:Atm	APN	9	53,480,665 (GRCm38)	missense	probably damaging	0.99
IGL02246:Atm	APN	9	53,527,185 (GRCm38)	missense	probably benign	0.12
IGL02259:Atm	APN	9	53,518,494 (GRCm38)	splice site	probably benign
IGL02351:Atm	APN	9	53,522,176 (GRCm38)	missense	probably benign	0.04
IGL02358:Atm	APN	9	53,522,176 (GRCm38)	missense	probably benign	0.04
IGL02387:Atm	APN	9	53,479,766 (GRCm38)	splice site	probably null
IGL02417:Atm	APN	9	53,479,695 (GRCm38)	missense	probably benign	0.00
IGL02422:Atm	APN	9	53,500,792 (GRCm38)	missense	probably damaging	1.00
IGL02445:Atm	APN	9	53,454,330 (GRCm38)	missense	probably benign	0.00
IGL02492:Atm	APN	9	53,455,859 (GRCm38)	missense	probably damaging	0.99
IGL02513:Atm	APN	9	53,497,262 (GRCm38)	splice site	probably benign
IGL02633:Atm	APN	9	53,448,153 (GRCm38)	missense	probably damaging	1.00
IGL02634:Atm	APN	9	53,516,563 (GRCm38)	missense	probably benign	0.00
IGL02959:Atm	APN	9	53,471,418 (GRCm38)	missense	probably damaging	1.00
IGL02965:Atm	APN	9	53,453,563 (GRCm38)	missense	probably damaging	1.00
IGL03085:Atm	APN	9	53,484,171 (GRCm38)	missense	possibly damaging	0.89
antebellum	UTSW	9	53,518,559 (GRCm38)	nonsense	probably null
bull_run	UTSW	9	53,487,922 (GRCm38)	missense	probably benign	0.09
Civil	UTSW	9	53,492,268 (GRCm38)	missense	possibly damaging	0.78
gettysburg	UTSW	9	53,455,988 (GRCm38)	splice site	probably null
Grant	UTSW	9	53,511,917 (GRCm38)	nonsense	probably null
Indicative	UTSW	9	53,445,376 (GRCm38)	splice site	probably null
Marker	UTSW	9	53,454,279 (GRCm38)	splice site	probably benign
maunder	UTSW	9	53,499,197 (GRCm38)	nonsense	probably null
mockingbird	UTSW	9	53,516,467 (GRCm38)	nonsense	probably null
mockingbird2	UTSW	9	53,488,587 (GRCm38)	missense	probably damaging	1.00
osphere	UTSW	9	53,479,673 (GRCm38)	missense	probably damaging	0.99
shiloh	UTSW	9	53,465,298 (GRCm38)	missense	probably damaging	1.00
Strato	UTSW	9	53,503,018 (GRCm38)	missense	probably damaging	1.00
thrasher	UTSW	9	53,445,507 (GRCm38)	missense	probably benign	0.01
Tropo	UTSW	9	53,531,648 (GRCm38)	missense	probably damaging	1.00
P0019:Atm	UTSW	9	53,465,028 (GRCm38)	splice site	probably benign
PIT4403001:Atm	UTSW	9	53,500,982 (GRCm38)	missense	probably benign
PIT4687001:Atm	UTSW	9	53,486,812 (GRCm38)	critical splice donor site	probably null
R0004:Atm	UTSW	9	53,453,528 (GRCm38)	splice site	probably benign
R0035:Atm	UTSW	9	53,513,180 (GRCm38)	missense	probably benign	0.01
R0098:Atm	UTSW	9	53,518,569 (GRCm38)	missense	probably benign	0.10
R0098:Atm	UTSW	9	53,518,569 (GRCm38)	missense	probably benign	0.10
R0201:Atm	UTSW	9	53,454,279 (GRCm38)	splice site	probably benign
R0304:Atm	UTSW	9	53,516,344 (GRCm38)	missense	probably benign	0.34
R0308:Atm	UTSW	9	53,454,473 (GRCm38)	splice site	probably null
R0362:Atm	UTSW	9	53,458,838 (GRCm38)	missense	possibly damaging	0.90
R0470:Atm	UTSW	9	53,460,966 (GRCm38)	missense	probably damaging	1.00
R0513:Atm	UTSW	9	53,503,948 (GRCm38)	missense	probably benign	0.00
R0589:Atm	UTSW	9	53,490,192 (GRCm38)	missense	possibly damaging	0.51
R0617:Atm	UTSW	9	53,458,941 (GRCm38)	nonsense	probably null
R0630:Atm	UTSW	9	53,531,622 (GRCm38)	splice site	probably benign
R0652:Atm	UTSW	9	53,486,014 (GRCm38)	missense	probably damaging	0.98
R0698:Atm	UTSW	9	53,515,239 (GRCm38)	missense	probably damaging	1.00
R0737:Atm	UTSW	9	53,456,566 (GRCm38)	missense	probably damaging	1.00
R0885:Atm	UTSW	9	53,459,823 (GRCm38)	missense	probably benign
R0947:Atm	UTSW	9	53,504,092 (GRCm38)	missense	probably benign	0.01
R0948:Atm	UTSW	9	53,495,958 (GRCm38)	missense	probably benign
R1144:Atm	UTSW	9	53,511,698 (GRCm38)	splice site	probably benign
R1252:Atm	UTSW	9	53,455,840 (GRCm38)	missense	probably damaging	1.00
R1295:Atm	UTSW	9	53,456,530 (GRCm38)	missense	probably damaging	1.00
R1296:Atm	UTSW	9	53,456,530 (GRCm38)	missense	probably damaging	1.00
R1419:Atm	UTSW	9	53,457,489 (GRCm38)	missense	probably benign	0.00
R1477:Atm	UTSW	9	53,464,273 (GRCm38)	missense	probably benign	0.00
R1596:Atm	UTSW	9	53,453,378 (GRCm38)	missense	probably damaging	1.00
R1630:Atm	UTSW	9	53,479,673 (GRCm38)	missense	probably damaging	0.99
R1667:Atm	UTSW	9	53,500,932 (GRCm38)	missense	probably damaging	1.00
R1681:Atm	UTSW	9	53,522,155 (GRCm38)	missense	possibly damaging	0.94
R1703:Atm	UTSW	9	53,500,700 (GRCm38)	missense	probably benign
R1817:Atm	UTSW	9	53,492,233 (GRCm38)	splice site	probably benign
R1840:Atm	UTSW	9	53,456,530 (GRCm38)	missense	probably damaging	1.00
R1848:Atm	UTSW	9	53,468,012 (GRCm38)	missense	probably benign	0.06
R1906:Atm	UTSW	9	53,506,568 (GRCm38)	missense	probably damaging	1.00
R1958:Atm	UTSW	9	53,471,418 (GRCm38)	missense	probably damaging	1.00
R2108:Atm	UTSW	9	53,443,997 (GRCm38)	missense	probably damaging	1.00
R2116:Atm	UTSW	9	53,500,969 (GRCm38)	missense	probably benign	0.36
R2134:Atm	UTSW	9	53,467,964 (GRCm38)	critical splice donor site	probably null
R2137:Atm	UTSW	9	53,453,375 (GRCm38)	missense	probably damaging	1.00
R2291:Atm	UTSW	9	53,490,909 (GRCm38)	splice site	probably null
R2348:Atm	UTSW	9	53,492,268 (GRCm38)	missense	possibly damaging	0.78
R2483:Atm	UTSW	9	53,510,266 (GRCm38)	missense	probably damaging	1.00
R2567:Atm	UTSW	9	53,457,470 (GRCm38)	missense	possibly damaging	0.72
R2897:Atm	UTSW	9	53,507,805 (GRCm38)	missense	probably damaging	0.99
R2939:Atm	UTSW	9	53,494,711 (GRCm38)	missense	probably damaging	1.00
R3008:Atm	UTSW	9	53,480,750 (GRCm38)	missense	probably benign	0.00
R3236:Atm	UTSW	9	53,479,748 (GRCm38)	missense	probably benign	0.15
R3847:Atm	UTSW	9	53,503,075 (GRCm38)	missense	possibly damaging	0.94
R3889:Atm	UTSW	9	53,506,636 (GRCm38)	splice site	probably benign
R3919:Atm	UTSW	9	53,492,278 (GRCm38)	missense	probably benign	0.00
R4125:Atm	UTSW	9	53,450,621 (GRCm38)	missense	probably damaging	1.00
R4222:Atm	UTSW	9	53,480,669 (GRCm38)	missense	probably benign
R4395:Atm	UTSW	9	53,465,227 (GRCm38)	missense	probably benign	0.09
R4466:Atm	UTSW	9	53,448,169 (GRCm38)	nonsense	probably null
R4502:Atm	UTSW	9	53,495,946 (GRCm38)	missense	possibly damaging	0.92
R4514:Atm	UTSW	9	53,493,039 (GRCm38)	missense	probably damaging	0.99
R4528:Atm	UTSW	9	53,500,759 (GRCm38)	missense	probably benign	0.39
R4593:Atm	UTSW	9	53,453,594 (GRCm38)	missense	possibly damaging	0.55
R4627:Atm	UTSW	9	53,456,506 (GRCm38)	missense	possibly damaging	0.79
R4634:Atm	UTSW	9	53,531,733 (GRCm38)	missense	probably benign	0.01
R4665:Atm	UTSW	9	53,464,229 (GRCm38)	missense	probably benign	0.00
R4672:Atm	UTSW	9	53,522,201 (GRCm38)	missense	probably damaging	0.99
R4741:Atm	UTSW	9	53,453,607 (GRCm38)	missense	probably benign	0.10
R4808:Atm	UTSW	9	53,445,495 (GRCm38)	missense	probably damaging	0.99
R4959:Atm	UTSW	9	53,515,301 (GRCm38)	missense	probably benign
R4996:Atm	UTSW	9	53,524,507 (GRCm38)	missense	probably benign	0.09
R5030:Atm	UTSW	9	53,520,109 (GRCm38)	nonsense	probably null
R5214:Atm	UTSW	9	53,491,027 (GRCm38)	missense	probably benign	0.09
R5260:Atm	UTSW	9	53,506,611 (GRCm38)	missense	probably damaging	0.99
R5311:Atm	UTSW	9	53,518,623 (GRCm38)	missense	probably benign	0.00
R5394:Atm	UTSW	9	53,507,777 (GRCm38)	critical splice donor site	probably null
R5400:Atm	UTSW	9	53,503,018 (GRCm38)	missense	probably damaging	1.00
R5436:Atm	UTSW	9	53,459,804 (GRCm38)	missense	probably benign	0.00
R5441:Atm	UTSW	9	53,516,467 (GRCm38)	nonsense	probably null
R5569:Atm	UTSW	9	53,516,450 (GRCm38)	nonsense	probably null
R5856:Atm	UTSW	9	53,495,955 (GRCm38)	missense	possibly damaging	0.64
R5891:Atm	UTSW	9	53,497,159 (GRCm38)	missense	probably benign
R5910:Atm	UTSW	9	53,448,080 (GRCm38)	missense	probably damaging	0.96
R6054:Atm	UTSW	9	53,459,873 (GRCm38)	missense	probably damaging	1.00
R6062:Atm	UTSW	9	53,488,587 (GRCm38)	missense	probably damaging	1.00
R6092:Atm	UTSW	9	53,524,414 (GRCm38)	missense	probably damaging	1.00
R6127:Atm	UTSW	9	53,524,509 (GRCm38)	missense	probably damaging	1.00
R6160:Atm	UTSW	9	53,490,959 (GRCm38)	missense	probably benign	0.04
R6267:Atm	UTSW	9	53,444,000 (GRCm38)	missense	probably damaging	1.00
R6273:Atm	UTSW	9	53,487,922 (GRCm38)	missense	probably benign	0.09
R6284:Atm	UTSW	9	53,445,376 (GRCm38)	splice site	probably null
R6478:Atm	UTSW	9	53,490,254 (GRCm38)	missense	probably damaging	1.00
R6547:Atm	UTSW	9	53,440,157 (GRCm38)	missense	probably damaging	1.00
R6549:Atm	UTSW	9	53,493,177 (GRCm38)	missense	probably benign	0.00
R6704:Atm	UTSW	9	53,458,853 (GRCm38)	missense	probably benign	0.02
R6715:Atm	UTSW	9	53,531,648 (GRCm38)	missense	probably damaging	1.00
R6737:Atm	UTSW	9	53,486,051 (GRCm38)	missense	probably benign	0.30
R6759:Atm	UTSW	9	53,518,559 (GRCm38)	nonsense	probably null
R6766:Atm	UTSW	9	53,490,282 (GRCm38)	missense	probably damaging	0.99
R6813:Atm	UTSW	9	53,497,235 (GRCm38)	missense	probably benign	0.00
R6852:Atm	UTSW	9	53,482,430 (GRCm38)	missense	possibly damaging	0.93
R7064:Atm	UTSW	9	53,507,881 (GRCm38)	missense	probably benign	0.02
R7208:Atm	UTSW	9	53,512,008 (GRCm38)	splice site	probably null
R7211:Atm	UTSW	9	53,488,560 (GRCm38)	missense	probably benign	0.01
R7220:Atm	UTSW	9	53,511,917 (GRCm38)	nonsense	probably null
R7336:Atm	UTSW	9	53,462,503 (GRCm38)	missense	possibly damaging	0.47
R7363:Atm	UTSW	9	53,465,298 (GRCm38)	missense	probably damaging	1.00
R7378:Atm	UTSW	9	53,453,437 (GRCm38)	critical splice acceptor site	probably null
R7472:Atm	UTSW	9	53,448,125 (GRCm38)	missense	possibly damaging	0.81
R7487:Atm	UTSW	9	53,524,354 (GRCm38)	missense	probably benign
R7497:Atm	UTSW	9	53,511,891 (GRCm38)	missense	probably benign	0.00
R7584:Atm	UTSW	9	53,513,127 (GRCm38)	missense	probably damaging	0.99
R7624:Atm	UTSW	9	53,454,768 (GRCm38)	missense	probably damaging	0.99
R7653:Atm	UTSW	9	53,490,302 (GRCm38)	nonsense	probably null
R7660:Atm	UTSW	9	53,445,507 (GRCm38)	missense	probably benign	0.01
R7679:Atm	UTSW	9	53,442,497 (GRCm38)	missense	probably damaging	1.00
R7720:Atm	UTSW	9	53,522,239 (GRCm38)	missense	possibly damaging	0.54
R8221:Atm	UTSW	9	53,455,988 (GRCm38)	splice site	probably null
R8247:Atm	UTSW	9	53,450,570 (GRCm38)	missense
R8334:Atm	UTSW	9	53,522,273 (GRCm38)	missense	probably benign	0.00
R8503:Atm	UTSW	9	53,488,052 (GRCm38)	missense	probably damaging	0.99
R8552:Atm	UTSW	9	53,524,497 (GRCm38)	missense	probably damaging	1.00
R8749:Atm	UTSW	9	53,499,197 (GRCm38)	nonsense	probably null
R8838:Atm	UTSW	9	53,516,551 (GRCm38)	missense	probably damaging	0.99
R9126:Atm	UTSW	9	53,458,834 (GRCm38)	missense	probably benign	0.01
R9131:Atm	UTSW	9	53,533,744 (GRCm38)	missense	probably benign	0.10
R9191:Atm	UTSW	9	53,527,290 (GRCm38)	missense	probably benign	0.29
R9257:Atm	UTSW	9	53,495,850 (GRCm38)	critical splice donor site	probably null
R9473:Atm	UTSW	9	53,498,972 (GRCm38)	missense	probably benign
R9558:Atm	UTSW	9	53,500,781 (GRCm38)	missense	probably benign	0.00
R9598:Atm	UTSW	9	53,520,081 (GRCm38)	missense	probably benign	0.34
R9717:Atm	UTSW	9	53,516,517 (GRCm38)	missense	probably damaging	1.00
R9794:Atm	UTSW	9	53,518,567 (GRCm38)	missense	probably benign
X0067:Atm	UTSW	9	53,479,694 (GRCm38)	missense	probably benign	0.00
Z1088:Atm	UTSW	9	53,531,687 (GRCm38)	missense	probably damaging	1.00

Posted On

2015-12-18