Incidental Mutation 'IGL02960:Gm3159'
ID365322
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm3159
Ensembl Gene ENSMUSG00000095056
Gene Namepredicted gene 3159
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.069) question?
Stock #IGL02960
Quality Score
Status
Chromosome14
Chromosomal Location4397526-4406347 bp(+) (GRCm38)
Type of Mutationcritical splice donor site (1 bp from exon)
DNA Base Change (assembly) G to A at 4400552 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000133201 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000164038] [ENSMUST00000167245] [ENSMUST00000177764]
Predicted Effect probably null
Transcript: ENSMUST00000164038
SMART Domains Protein: ENSMUSP00000126043
Gene: ENSMUSG00000095056

DomainStartEndE-ValueType
Pfam:Takusan 46 129 1.3e-30 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000167245
SMART Domains Protein: ENSMUSP00000133201
Gene: ENSMUSG00000095056

DomainStartEndE-ValueType
Pfam:Takusan 48 128 5.1e-21 PFAM
transmembrane domain 240 262 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000177764
AA Change: V204I

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000137464
Gene: ENSMUSG00000095056
AA Change: V204I

DomainStartEndE-ValueType
Pfam:Takusan 46 129 5.6e-30 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700129C05Rik G A 14: 59,142,808 R14C probably benign Het
Adam29 A T 8: 55,872,666 L251* probably null Het
Atpaf2 T C 11: 60,405,824 E161G probably damaging Het
Brwd1 T C 16: 96,057,466 D381G probably damaging Het
Cept1 T A 3: 106,539,396 R45* probably null Het
Col3a1 A G 1: 45,328,455 E273G unknown Het
Cuzd1 T C 7: 131,320,103 N57D probably benign Het
Cyp2b13 A G 7: 26,061,676 K53E probably benign Het
Fadd T C 7: 144,580,539 E203G probably benign Het
Gm14548 T C 7: 3,897,079 T175A possibly damaging Het
Gpr137c T C 14: 45,246,433 F206L possibly damaging Het
Hephl1 G T 9: 15,084,319 T471N probably damaging Het
Ido1 A T 8: 24,593,329 probably benign Het
Krt40 C T 11: 99,539,867 probably null Het
Lrp2 T A 2: 69,455,453 probably benign Het
Lrrc8a T A 2: 30,257,013 L613H probably damaging Het
Mettl14 A G 3: 123,374,885 Y169H probably damaging Het
Nlrp4a A G 7: 26,449,730 Q254R probably benign Het
Olfr1211 A C 2: 88,929,784 M177R possibly damaging Het
Olfr1356 A T 10: 78,847,537 I126N probably damaging Het
Pkhd1 A T 1: 20,377,446 M2241K possibly damaging Het
Ptprd G A 4: 76,128,868 S387L probably damaging Het
Ryr1 A C 7: 29,060,053 L3264R probably damaging Het
Serpina16 G A 12: 103,675,379 T29I probably benign Het
Slc9a7 A G X: 20,186,143 M237T probably benign Het
Tbck A G 3: 132,722,783 T300A probably benign Het
Tcaf1 A C 6: 42,686,459 D162E probably benign Het
Unc80 G A 1: 66,678,058 probably benign Het
Usp17le A C 7: 104,768,740 H398Q probably benign Het
Utp15 G A 13: 98,252,881 T303M probably benign Het
Vmn2r86 A C 10: 130,453,767 D86E possibly damaging Het
Zmym2 T A 14: 56,938,413 C822S probably benign Het
Zp3r T C 1: 130,583,438 D336G possibly damaging Het
Zpr1 A G 9: 46,273,551 H82R probably damaging Het
Other mutations in Gm3159
AlleleSourceChrCoordTypePredicted EffectPPH Score
R1398:Gm3159 UTSW 14 4398586 nonsense probably null
R4477:Gm3159 UTSW 14 4398584 missense probably damaging 1.00
R4479:Gm3159 UTSW 14 4398584 missense probably damaging 1.00
R4480:Gm3159 UTSW 14 4398584 missense probably damaging 1.00
R5677:Gm3159 UTSW 14 4398582 missense probably damaging 0.97
R6957:Gm3159 UTSW 14 4398530 missense possibly damaging 0.94
R7366:Gm3159 UTSW 14 4398525 missense probably benign 0.27
R7514:Gm3159 UTSW 14 4399690 missense probably damaging 1.00
R7796:Gm3159 UTSW 14 4400560 makesense probably null
R7799:Gm3159 UTSW 14 4397585 unclassified probably benign
Posted On2015-12-18