Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02960:Gm3159'

365322

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm3159

Ensembl Gene

ENSMUSG00000095056

Gene Name

predicted gene 3159

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.071) question?

Stock #

IGL02960

Quality Score

Status

Chromosome

Chromosomal Location

18063745-18072184 bp(-) (GRCm39)

Type of Mutation

critical splice donor site (1 bp from exon)

DNA Base Change (assembly)

G to A at 4400552 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000133201 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000164038] [ENSMUST00000167245] [ENSMUST00000177764]

AlphaFold

K7N760

Predicted Effect

probably null
Transcript: ENSMUST00000164038

SMART Domains

Protein: ENSMUSP00000126043
Gene: ENSMUSG00000095056

Domain	Start	End	E-Value	Type
Pfam:Takusan	46	129	1.3e-30	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000167245

SMART Domains

Protein: ENSMUSP00000133201
Gene: ENSMUSG00000095056

Domain	Start	End	E-Value	Type
Pfam:Takusan	48	128	5.1e-21	PFAM
transmembrane domain	240	262	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000177764
AA Change: V204I

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000137464
Gene: ENSMUSG00000095056
AA Change: V204I

Domain	Start	End	E-Value	Type
Pfam:Takusan	46	129	5.6e-30	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 34 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700129C05Rik	G	A	14: 59,380,257 (GRCm39)	R14C	probably benign	Het
Adam29	A	T	8: 56,325,701 (GRCm39)	L251*	probably null	Het
Atpaf2	T	C	11: 60,296,650 (GRCm39)	E161G	probably damaging	Het
Brwd1	T	C	16: 95,858,666 (GRCm39)	D381G	probably damaging	Het
Cept1	T	A	3: 106,446,712 (GRCm39)	R45*	probably null	Het
Col3a1	A	G	1: 45,367,615 (GRCm39)	E273G	unknown	Het
Cuzd1	T	C	7: 130,921,832 (GRCm39)	N57D	probably benign	Het
Cyp2b13	A	G	7: 25,761,101 (GRCm39)	K53E	probably benign	Het
Fadd	T	C	7: 144,134,276 (GRCm39)	E203G	probably benign	Het
Gpr137c	T	C	14: 45,483,890 (GRCm39)	F206L	possibly damaging	Het
Hephl1	G	T	9: 14,995,615 (GRCm39)	T471N	probably damaging	Het
Ido1	A	T	8: 25,083,345 (GRCm39)		probably benign	Het
Krt40	C	T	11: 99,430,693 (GRCm39)		probably null	Het
Lrp2	T	A	2: 69,285,797 (GRCm39)		probably benign	Het
Lrrc8a	T	A	2: 30,147,025 (GRCm39)	L613H	probably damaging	Het
Mettl14	A	G	3: 123,168,534 (GRCm39)	Y169H	probably damaging	Het
Nlrp4a	A	G	7: 26,149,155 (GRCm39)	Q254R	probably benign	Het
Or4c15	A	C	2: 88,760,128 (GRCm39)	M177R	possibly damaging	Het
Or7c70	A	T	10: 78,683,371 (GRCm39)	I126N	probably damaging	Het
Pira12	T	C	7: 3,900,078 (GRCm39)	T175A	possibly damaging	Het
Pkhd1	A	T	1: 20,447,670 (GRCm39)	M2241K	possibly damaging	Het
Ptprd	G	A	4: 76,047,105 (GRCm39)	S387L	probably damaging	Het
Ryr1	A	C	7: 28,759,478 (GRCm39)	L3264R	probably damaging	Het
Serpina16	G	A	12: 103,641,638 (GRCm39)	T29I	probably benign	Het
Slc9a7	A	G	X: 20,052,382 (GRCm39)	M237T	probably benign	Het
Tbck	A	G	3: 132,428,544 (GRCm39)	T300A	probably benign	Het
Tcaf1	A	C	6: 42,663,393 (GRCm39)	D162E	probably benign	Het
Unc80	G	A	1: 66,717,217 (GRCm39)		probably benign	Het
Usp17le	A	C	7: 104,417,947 (GRCm39)	H398Q	probably benign	Het
Utp15	G	A	13: 98,389,389 (GRCm39)	T303M	probably benign	Het
Vmn2r86	A	C	10: 130,289,636 (GRCm39)	D86E	possibly damaging	Het
Zmym2	T	A	14: 57,175,870 (GRCm39)	C822S	probably benign	Het
Zp3r	T	C	1: 130,511,175 (GRCm39)	D336G	possibly damaging	Het
Zpr1	A	G	9: 46,184,849 (GRCm39)	H82R	probably damaging	Het

Other mutations in Gm3159

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R1398:Gm3159	UTSW	14	4,398,586 (GRCm38)	nonsense	probably null
R4477:Gm3159	UTSW	14	4,398,584 (GRCm38)	missense	probably damaging	1.00
R4479:Gm3159	UTSW	14	4,398,584 (GRCm38)	missense	probably damaging	1.00
R4480:Gm3159	UTSW	14	4,398,584 (GRCm38)	missense	probably damaging	1.00
R5677:Gm3159	UTSW	14	4,398,582 (GRCm38)	missense	probably damaging	0.97
R6957:Gm3159	UTSW	14	4,398,530 (GRCm38)	missense	possibly damaging	0.94
R7366:Gm3159	UTSW	14	4,398,525 (GRCm38)	missense	probably benign	0.27
R7514:Gm3159	UTSW	14	4,399,690 (GRCm38)	missense	probably damaging	1.00
R7796:Gm3159	UTSW	14	4,400,560 (GRCm38)	makesense	probably null
R7799:Gm3159	UTSW	14	4,397,585 (GRCm38)	unclassified	probably benign
R8486:Gm3159	UTSW	14	4,400,520 (GRCm38)	missense	probably damaging	1.00
R8493:Gm3159	UTSW	14	4,398,567 (GRCm38)	missense	probably damaging	1.00
R9345:Gm3159	UTSW	14	4,398,488 (GRCm38)	missense	probably benign	0.31

Posted On

2015-12-18