Incidental Mutation 'IGL02960:Gm3159'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm3159
Ensembl Gene ENSMUSG00000095056
Gene Namepredicted gene 3159
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.069) question?
Stock #IGL02960
Quality Score
Chromosomal Location4397526-4406347 bp(+) (GRCm38)
Type of Mutationcritical splice donor site (1 bp from exon)
DNA Base Change (assembly) G to A at 4400552 bp
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000133201 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000164038] [ENSMUST00000167245] [ENSMUST00000177764]
Predicted Effect probably null
Transcript: ENSMUST00000164038
SMART Domains Protein: ENSMUSP00000126043
Gene: ENSMUSG00000095056

Pfam:Takusan 46 129 1.3e-30 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000167245
SMART Domains Protein: ENSMUSP00000133201
Gene: ENSMUSG00000095056

Pfam:Takusan 48 128 5.1e-21 PFAM
transmembrane domain 240 262 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000177764
AA Change: V204I

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000137464
Gene: ENSMUSG00000095056
AA Change: V204I

Pfam:Takusan 46 129 5.6e-30 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700129C05Rik G A 14: 59,142,808 R14C probably benign Het
Adam29 A T 8: 55,872,666 L251* probably null Het
Atpaf2 T C 11: 60,405,824 E161G probably damaging Het
Brwd1 T C 16: 96,057,466 D381G probably damaging Het
Cept1 T A 3: 106,539,396 R45* probably null Het
Col3a1 A G 1: 45,328,455 E273G unknown Het
Cuzd1 T C 7: 131,320,103 N57D probably benign Het
Cyp2b13 A G 7: 26,061,676 K53E probably benign Het
Fadd T C 7: 144,580,539 E203G probably benign Het
Gm14548 T C 7: 3,897,079 T175A possibly damaging Het
Gpr137c T C 14: 45,246,433 F206L possibly damaging Het
Hephl1 G T 9: 15,084,319 T471N probably damaging Het
Ido1 A T 8: 24,593,329 probably benign Het
Krt40 C T 11: 99,539,867 probably null Het
Lrp2 T A 2: 69,455,453 probably benign Het
Lrrc8a T A 2: 30,257,013 L613H probably damaging Het
Mettl14 A G 3: 123,374,885 Y169H probably damaging Het
Nlrp4a A G 7: 26,449,730 Q254R probably benign Het
Olfr1211 A C 2: 88,929,784 M177R possibly damaging Het
Olfr1356 A T 10: 78,847,537 I126N probably damaging Het
Pkhd1 A T 1: 20,377,446 M2241K possibly damaging Het
Ptprd G A 4: 76,128,868 S387L probably damaging Het
Ryr1 A C 7: 29,060,053 L3264R probably damaging Het
Serpina16 G A 12: 103,675,379 T29I probably benign Het
Slc9a7 A G X: 20,186,143 M237T probably benign Het
Tbck A G 3: 132,722,783 T300A probably benign Het
Tcaf1 A C 6: 42,686,459 D162E probably benign Het
Unc80 G A 1: 66,678,058 probably benign Het
Usp17le A C 7: 104,768,740 H398Q probably benign Het
Utp15 G A 13: 98,252,881 T303M probably benign Het
Vmn2r86 A C 10: 130,453,767 D86E possibly damaging Het
Zmym2 T A 14: 56,938,413 C822S probably benign Het
Zp3r T C 1: 130,583,438 D336G possibly damaging Het
Zpr1 A G 9: 46,273,551 H82R probably damaging Het
Other mutations in Gm3159
AlleleSourceChrCoordTypePredicted EffectPPH Score
R1398:Gm3159 UTSW 14 4398586 nonsense probably null
R4477:Gm3159 UTSW 14 4398584 missense probably damaging 1.00
R4479:Gm3159 UTSW 14 4398584 missense probably damaging 1.00
R4480:Gm3159 UTSW 14 4398584 missense probably damaging 1.00
R5677:Gm3159 UTSW 14 4398582 missense probably damaging 0.97
R6957:Gm3159 UTSW 14 4398530 missense possibly damaging 0.94
R7366:Gm3159 UTSW 14 4398525 missense probably benign 0.27
R7514:Gm3159 UTSW 14 4399690 missense probably damaging 1.00
R7796:Gm3159 UTSW 14 4400560 makesense probably null
R7799:Gm3159 UTSW 14 4397585 unclassified probably benign
Posted On2015-12-18