Incidental Mutation 'IGL02964:Vmn1r32'
ID365470
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r32
Ensembl Gene ENSMUSG00000062905
Gene Namevomeronasal 1 receptor 32
SynonymsV1rc15
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.050) question?
Stock #IGL02964
Quality Score
Status
Chromosome6
Chromosomal Location66552180-66560096 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 66552938 bp
ZygosityHeterozygous
Amino Acid Change Asparagine to Aspartic acid at position 285 (N285D)
Ref Sequence ENSEMBL: ENSMUSP00000153723 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000079584] [ENSMUST00000227014]
Predicted Effect probably benign
Transcript: ENSMUST00000079584
AA Change: N285D

PolyPhen 2 Score 0.365 (Sensitivity: 0.90; Specificity: 0.89)
SMART Domains Protein: ENSMUSP00000078536
Gene: ENSMUSG00000062905
AA Change: N285D

DomainStartEndE-ValueType
Pfam:V1R 28 293 9.7e-56 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000227014
AA Change: N285D

PolyPhen 2 Score 0.365 (Sensitivity: 0.90; Specificity: 0.89)
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 46 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcc3 T C 11: 94,351,810 I1364V possibly damaging Het
Adamts19 T A 18: 58,988,965 I813K probably damaging Het
Adamtsl1 G T 4: 86,424,357 C1703F probably damaging Het
Atp2b4 T A 1: 133,730,565 T536S probably damaging Het
Capg T A 6: 72,562,844 I340N probably damaging Het
Casc3 T A 11: 98,828,923 M567K probably damaging Het
Chmp1a T C 8: 123,208,067 E50G probably damaging Het
Cryba1 T C 11: 77,719,381 probably benign Het
Dnah8 T A 17: 30,746,761 Y2356N probably damaging Het
Ercc6 T G 14: 32,570,103 S1141R probably benign Het
Exd2 T A 12: 80,480,528 V165D probably damaging Het
Fbln1 A T 15: 85,231,462 E233V probably damaging Het
Ftsj3 T C 11: 106,252,337 K384E probably damaging Het
Ggt5 A G 10: 75,604,128 I188V probably benign Het
Gm42742 A T 7: 127,016,846 S26T probably damaging Het
Gucy1a2 T A 9: 3,759,542 D449E probably damaging Het
Igfbp7 C T 5: 77,351,341 S239N possibly damaging Het
Klf11 C T 12: 24,655,627 A360V probably damaging Het
Kmt2e T A 5: 23,467,100 probably benign Het
Magea8 A T X: 154,986,682 C144S probably damaging Het
Med4 A G 14: 73,517,921 Q223R probably damaging Het
Mmd2 G T 5: 142,569,477 F153L probably damaging Het
Nav3 C A 10: 109,736,953 R1615L probably damaging Het
Nisch A G 14: 31,180,812 probably benign Het
Nr1i3 A T 1: 171,214,395 Y16F probably benign Het
Olfr1134 C A 2: 87,656,714 C69F probably damaging Het
Olfr828 A G 9: 18,815,728 C189R probably damaging Het
Olfr860 G A 9: 19,846,254 R122* probably null Het
Olfr954 A G 9: 39,461,781 T117A possibly damaging Het
Ppil6 C A 10: 41,507,483 H252N probably benign Het
Ppp6r2 C T 15: 89,259,175 P175L probably damaging Het
Psme4 T A 11: 30,791,095 Y90* probably null Het
Rbm20 C A 19: 53,813,702 L214I probably benign Het
Rhox2f T C X: 37,571,681 V24A probably benign Het
Scnm1 T C 3: 95,133,037 K96E probably benign Het
Sec16a A C 2: 26,419,723 D2090E probably benign Het
Smg6 T C 11: 74,930,750 probably null Het
Snx2 T C 18: 53,194,558 S119P probably benign Het
Stam A G 2: 14,115,968 probably benign Het
Sult2b1 T A 7: 45,735,274 E126V probably benign Het
Tor1aip1 T C 1: 156,035,844 E131G probably damaging Het
Ttn C T 2: 76,788,696 C14367Y probably damaging Het
Ubr4 T C 4: 139,407,820 F821S possibly damaging Het
Vmn2r23 T C 6: 123,741,782 L698P possibly damaging Het
Wnt8a T A 18: 34,542,421 L18Q possibly damaging Het
Zfp747 T C 7: 127,374,494 E168G probably benign Het
Other mutations in Vmn1r32
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01449:Vmn1r32 APN 6 66552932 missense probably benign
IGL02399:Vmn1r32 APN 6 66552929 missense probably benign 0.18
IGL03161:Vmn1r32 APN 6 66553220 missense possibly damaging 0.65
IGL03244:Vmn1r32 APN 6 66553505 missense probably damaging 1.00
IGL03248:Vmn1r32 APN 6 66552913 missense possibly damaging 0.82
R0668:Vmn1r32 UTSW 6 66553660 missense possibly damaging 0.90
R0732:Vmn1r32 UTSW 6 66553706 missense probably benign 0.01
R1205:Vmn1r32 UTSW 6 66553555 missense probably benign 0.01
R1638:Vmn1r32 UTSW 6 66552955 missense possibly damaging 0.53
R1732:Vmn1r32 UTSW 6 66553301 missense probably benign 0.19
R2049:Vmn1r32 UTSW 6 66553561 missense probably damaging 1.00
R2127:Vmn1r32 UTSW 6 66553549 missense probably benign 0.09
R3773:Vmn1r32 UTSW 6 66553367 missense probably benign 0.01
R3834:Vmn1r32 UTSW 6 66553663 missense probably benign 0.02
R3980:Vmn1r32 UTSW 6 66553714 missense probably damaging 0.98
R4737:Vmn1r32 UTSW 6 66553645 missense probably damaging 1.00
R5569:Vmn1r32 UTSW 6 66553172 missense probably damaging 0.98
R6382:Vmn1r32 UTSW 6 66553361 missense probably benign 0.07
R6894:Vmn1r32 UTSW 6 66553361 missense possibly damaging 0.94
R7394:Vmn1r32 UTSW 6 66553189 missense probably benign 0.06
R7980:Vmn1r32 UTSW 6 66553321 nonsense probably null
Posted On2015-12-18