Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02970:Vmn1r62'

365752

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r62

Ensembl Gene

ENSMUSG00000092579

Gene Name

vomeronasal 1 receptor 62

Synonyms

V3R2, V1rd8, V1rd2

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.043) question?

Stock #

IGL02970

Quality Score

Status

Chromosome

Chromosomal Location

5677603-5679598 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 5678567 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Asparagine at position 83 (Y83N)

Ref Sequence

ENSEMBL: ENSMUSP00000134168 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000173956]

AlphaFold

Q8R2C0

Predicted Effect

possibly damaging
Transcript: ENSMUST00000173956
AA Change: Y83N

PolyPhen 2 Score 0.640 (Sensitivity: 0.87; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000134168
Gene: ENSMUSG00000092579
AA Change: Y83N

Domain	Start	End	E-Value	Type
Pfam:TAS2R	1	296	2.8e-11	PFAM
Pfam:7tm_1	20	279	3.1e-6	PFAM
Pfam:V1R	31	299	4.2e-18	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700019A02Rik	C	T	1: 53,226,748 (GRCm39)	G5S	probably damaging	Het
A2ml1	A	T	6: 128,546,942 (GRCm39)	F396I	probably damaging	Het
BC051019	T	A	7: 109,315,262 (GRCm39)	N331I	probably benign	Het
Crocc	G	A	4: 140,757,557 (GRCm39)	S912L	possibly damaging	Het
Dcaf4	A	G	12: 83,575,989 (GRCm39)	D46G	probably damaging	Het
Dido1	C	T	2: 180,331,208 (GRCm39)	R80Q	probably damaging	Het
Dnase2b	A	G	3: 146,288,261 (GRCm39)	V278A	probably damaging	Het
Drosha	C	T	15: 12,914,042 (GRCm39)	L1106F	probably damaging	Het
Dsc3	C	A	18: 20,101,317 (GRCm39)	W692L	probably damaging	Het
F2	T	A	2: 91,455,896 (GRCm39)	Y579F	possibly damaging	Het
Fam43a	C	T	16: 30,419,922 (GRCm39)	R169C	probably damaging	Het
Gm9772	A	G	17: 22,225,540 (GRCm39)	F120S	probably damaging	Het
Gsdma3	T	C	11: 98,523,819 (GRCm39)	S251P	probably benign	Het
Hycc2	T	C	1: 58,578,776 (GRCm39)	E258G	probably damaging	Het
Itgam	G	A	7: 127,685,215 (GRCm39)	E443K	probably benign	Het
Kif18a	T	C	2: 109,118,233 (GRCm39)	V16A	probably damaging	Het
Lrrn3	T	G	12: 41,502,359 (GRCm39)	S653R	probably benign	Het
Map1b	A	T	13: 99,567,242 (GRCm39)	Y1826*	probably null	Het
Mbnl1	T	C	3: 60,520,844 (GRCm39)	F139S	probably damaging	Het
Micu3	T	C	8: 40,835,171 (GRCm39)	Y509H	possibly damaging	Het
Ncmap	T	C	4: 135,104,329 (GRCm39)	T17A	probably damaging	Het
Oas1h	T	A	5: 120,999,698 (GRCm39)	M61K	possibly damaging	Het
Otog	T	A	7: 45,945,291 (GRCm39)	W2183R	probably benign	Het
Pcdh15	T	C	10: 74,126,794 (GRCm39)		probably benign	Het
Plekho1	C	T	3: 95,898,214 (GRCm39)	V150I	probably damaging	Het
Ppargc1b	A	G	18: 61,431,837 (GRCm39)	S1004P	probably damaging	Het
Prf1	T	C	10: 61,135,957 (GRCm39)	S78P	probably benign	Het
Prss12	A	G	3: 123,276,411 (GRCm39)	S347G	probably benign	Het
Rai1	T	C	11: 60,076,559 (GRCm39)	S208P	probably damaging	Het
Sgms1	A	G	19: 32,137,165 (GRCm39)	Y134H	probably damaging	Het
Sult2a4	A	G	7: 13,643,831 (GRCm39)		probably benign	Het
T	C	T	17: 8,654,217 (GRCm39)	A134V	probably damaging	Het
Thoc5	A	G	11: 4,854,201 (GRCm39)	T187A	probably damaging	Het
Ticrr	A	G	7: 79,344,919 (GRCm39)	S1595G	probably benign	Het
Tiprl	A	G	1: 165,064,315 (GRCm39)	S30P	probably damaging	Het
Ttl	T	C	2: 128,917,990 (GRCm39)	S151P	probably damaging	Het
Ttn	T	A	2: 76,583,334 (GRCm39)	T22520S	probably damaging	Het
Usp54	G	A	14: 20,627,540 (GRCm39)	S420L	probably damaging	Het

Other mutations in Vmn1r62

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01337:Vmn1r62	APN	7	5,679,144 (GRCm39)	missense	probably damaging	1.00
IGL01650:Vmn1r62	APN	7	5,679,024 (GRCm39)	missense	probably damaging	1.00
IGL02892:Vmn1r62	APN	7	5,679,202 (GRCm39)	missense	probably benign
IGL03282:Vmn1r62	APN	7	5,678,547 (GRCm39)	missense	possibly damaging	0.93
R0470:Vmn1r62	UTSW	7	5,679,066 (GRCm39)	nonsense	probably null
R1416:Vmn1r62	UTSW	7	5,678,904 (GRCm39)	missense	probably damaging	1.00
R2149:Vmn1r62	UTSW	7	5,678,358 (GRCm39)	missense	probably benign	0.18
R4093:Vmn1r62	UTSW	7	5,678,943 (GRCm39)	missense	probably damaging	0.96
R4596:Vmn1r62	UTSW	7	5,678,306 (GRCm39)	start gained	probably benign
R4809:Vmn1r62	UTSW	7	5,678,866 (GRCm39)	missense	probably benign	0.41
R5669:Vmn1r62	UTSW	7	5,678,736 (GRCm39)	nonsense	probably null
R6262:Vmn1r62	UTSW	7	5,678,556 (GRCm39)	missense	probably damaging	1.00
R6312:Vmn1r62	UTSW	7	5,679,083 (GRCm39)	missense	possibly damaging	0.82
R6548:Vmn1r62	UTSW	7	5,678,769 (GRCm39)	missense	probably damaging	1.00
R7624:Vmn1r62	UTSW	7	5,678,600 (GRCm39)	missense	probably benign	0.01
R7710:Vmn1r62	UTSW	7	5,678,182 (GRCm39)	start gained	probably benign
R7896:Vmn1r62	UTSW	7	5,678,609 (GRCm39)	missense	probably damaging	1.00
R8117:Vmn1r62	UTSW	7	5,678,726 (GRCm39)	missense	possibly damaging	0.62
R8673:Vmn1r62	UTSW	7	5,678,277 (GRCm39)	start gained	probably benign
R8714:Vmn1r62	UTSW	7	5,678,629 (GRCm39)	nonsense	probably null
R8962:Vmn1r62	UTSW	7	5,678,601 (GRCm39)	missense	probably damaging	0.99
R9133:Vmn1r62	UTSW	7	5,679,062 (GRCm39)	missense	probably benign	0.01
R9246:Vmn1r62	UTSW	7	5,678,628 (GRCm39)	missense	probably damaging	1.00
R9360:Vmn1r62	UTSW	7	5,678,952 (GRCm39)	missense	probably damaging	0.99
RF007:Vmn1r62	UTSW	7	5,678,669 (GRCm39)	missense	probably benign	0.00

Posted On

2015-12-18