Incidental Mutation 'IGL02970:Gm9772'
ID365766
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm9772
Ensembl Gene ENSMUSG00000040775
Gene Namepredicted gene 9772
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.152) question?
Stock #IGL02970
Quality Score
Status
Chromosome17
Chromosomal Location22006510-22007301 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 22006559 bp
ZygosityHeterozygous
Amino Acid Change Phenylalanine to Serine at position 120 (F120S)
Ref Sequence ENSEMBL: ENSMUSP00000074538 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000075018] [ENSMUST00000174015]
Predicted Effect probably damaging
Transcript: ENSMUST00000075018
AA Change: F120S

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000074538
Gene: ENSMUSG00000040775
AA Change: F120S

DomainStartEndE-ValueType
ZnF_C2H2 6 28 1.01e-1 SMART
ZnF_C2H2 57 79 5.12e1 SMART
ZnF_C2H2 83 105 1.91e1 SMART
ZnF_C2H2 111 133 4.47e-3 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000172778
Predicted Effect probably benign
Transcript: ENSMUST00000174015
SMART Domains Protein: ENSMUSP00000133735
Gene: ENSMUSG00000053347

DomainStartEndE-ValueType
KRAB 13 60 3.79e-15 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 38 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700019A02Rik C T 1: 53,187,589 G5S probably damaging Het
A2ml1 A T 6: 128,569,979 F396I probably damaging Het
BC051019 T A 7: 109,716,055 N331I probably benign Het
Crocc G A 4: 141,030,246 S912L possibly damaging Het
Dcaf4 A G 12: 83,529,215 D46G probably damaging Het
Dido1 C T 2: 180,689,415 R80Q probably damaging Het
Dnase2b A G 3: 146,582,506 V278A probably damaging Het
Drosha C T 15: 12,913,956 L1106F probably damaging Het
Dsc3 C A 18: 19,968,260 W692L probably damaging Het
F2 T A 2: 91,625,551 Y579F possibly damaging Het
Fam126b T C 1: 58,539,617 E258G probably damaging Het
Fam43a C T 16: 30,601,104 R169C probably damaging Het
Gsdma3 T C 11: 98,632,993 S251P probably benign Het
Itgam G A 7: 128,086,043 E443K probably benign Het
Kif18a T C 2: 109,287,888 V16A probably damaging Het
Lrrn3 T G 12: 41,452,360 S653R probably benign Het
Map1b A T 13: 99,430,734 Y1826* probably null Het
Mbnl1 T C 3: 60,613,423 F139S probably damaging Het
Micu3 T C 8: 40,382,130 Y509H possibly damaging Het
Ncmap T C 4: 135,377,018 T17A probably damaging Het
Oas1h T A 5: 120,861,635 M61K possibly damaging Het
Otog T A 7: 46,295,867 W2183R probably benign Het
Pcdh15 T C 10: 74,290,962 probably benign Het
Plekho1 C T 3: 95,990,902 V150I probably damaging Het
Ppargc1b A G 18: 61,298,766 S1004P probably damaging Het
Prf1 T C 10: 61,300,178 S78P probably benign Het
Prss12 A G 3: 123,482,762 S347G probably benign Het
Rai1 T C 11: 60,185,733 S208P probably damaging Het
Sgms1 A G 19: 32,159,765 Y134H probably damaging Het
Sult2a4 A G 7: 13,909,906 probably benign Het
T C T 17: 8,435,385 A134V probably damaging Het
Thoc5 A G 11: 4,904,201 T187A probably damaging Het
Ticrr A G 7: 79,695,171 S1595G probably benign Het
Tiprl A G 1: 165,236,746 S30P probably damaging Het
Ttl T C 2: 129,076,070 S151P probably damaging Het
Ttn T A 2: 76,752,990 T22520S probably damaging Het
Usp54 G A 14: 20,577,472 S420L probably damaging Het
Vmn1r62 T A 7: 5,675,568 Y83N possibly damaging Het
Other mutations in Gm9772
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02232:Gm9772 APN 17 22007050 intron probably benign
R1456:Gm9772 UTSW 17 22007118 missense probably damaging 1.00
R2098:Gm9772 UTSW 17 22006637 missense probably benign 0.02
R4628:Gm9772 UTSW 17 22007207 missense probably damaging 0.99
R4647:Gm9772 UTSW 17 22007032 missense possibly damaging 0.57
R5145:Gm9772 UTSW 17 22007126 missense probably damaging 1.00
R7529:Gm9772 UTSW 17 22007159 missense probably benign 0.21
R7627:Gm9772 UTSW 17 22007179 missense probably damaging 1.00
Posted On2015-12-18