Incidental Mutation 'IGL02971:Vmn1r170'
ID365808
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r170
Ensembl Gene ENSMUSG00000094187
Gene Namevomeronasal 1 receptor 170
SynonymsGm5999
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.051) question?
Stock #IGL02971
Quality Score
Status
Chromosome7
Chromosomal Location23606175-23607089 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 23606334 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Phenylalanine at position 54 (I54F)
Ref Sequence ENSEMBL: ENSMUSP00000127655 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000170166]
Predicted Effect possibly damaging
Transcript: ENSMUST00000170166
AA Change: I54F

PolyPhen 2 Score 0.810 (Sensitivity: 0.84; Specificity: 0.93)
SMART Domains Protein: ENSMUSP00000127655
Gene: ENSMUSG00000094187
AA Change: I54F

DomainStartEndE-ValueType
Pfam:TAS2R 8 296 1.8e-13 PFAM
Pfam:7tm_1 30 287 3.6e-6 PFAM
Pfam:V1R 42 295 1.4e-20 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
A930018P22Rik C T 2: 104,123,219 T130I probably benign Het
Ahi1 T C 10: 21,000,551 L787P possibly damaging Het
Atf3 A G 1: 191,177,443 S10P probably benign Het
Cdr2l A G 11: 115,390,900 N77S probably damaging Het
Cnp A G 11: 100,576,699 D156G probably benign Het
Cntn3 A T 6: 102,168,933 D982E probably damaging Het
Col22a1 A G 15: 72,006,738 L190S probably damaging Het
Csmd3 C T 15: 47,913,929 probably benign Het
Dnah5 A G 15: 28,384,461 D3117G probably damaging Het
Dock5 T C 14: 67,757,109 E1834G probably null Het
Eea1 A G 10: 96,041,527 T1368A probably benign Het
Fam83f T C 15: 80,672,149 V78A probably benign Het
Fcgbp G A 7: 28,101,473 V1315I probably damaging Het
Fsd2 A T 7: 81,548,923 Y364* probably null Het
Gm21976 G A 13: 98,302,549 G16R probably null Het
Guca2b A G 4: 119,657,688 S59P probably damaging Het
Hars2 A G 18: 36,786,178 E123G probably damaging Het
Hdac2 A T 10: 37,000,374 K462* probably null Het
Huwe1 T A X: 151,927,626 probably benign Het
Iqgap3 T A 3: 88,090,304 N262K probably benign Het
Kat6b A G 14: 21,669,758 S1502G probably damaging Het
Mapkapk3 A T 9: 107,257,080 D328E probably benign Het
Mgea5 A G 19: 45,762,243 F671S probably damaging Het
Naca C T 10: 128,041,568 probably benign Het
Npffr1 T C 10: 61,614,139 V64A probably damaging Het
Olfr331 A G 11: 58,502,385 L57P probably damaging Het
Olfr918 T A 9: 38,673,268 M72L probably damaging Het
Pcca A G 14: 122,889,533 D718G probably damaging Het
Pde6a A C 18: 61,264,255 D670A probably damaging Het
Pramel7 T A 2: 87,490,073 E292V probably benign Het
Prmt9 A C 8: 77,565,069 M357L probably benign Het
Ptgfr A T 3: 151,835,326 S182T probably benign Het
Rtraf A T 14: 19,816,192 M152K possibly damaging Het
Satb1 T C 17: 51,742,689 D579G possibly damaging Het
Serpinb6a A G 13: 33,931,470 probably null Het
Slc5a9 T C 4: 111,890,300 I297V possibly damaging Het
Slf1 T A 13: 77,047,104 probably benign Het
St8sia2 C T 7: 73,966,811 V139M probably damaging Het
Tas2r114 T C 6: 131,689,280 M262V probably benign Het
Tmem147 A G 7: 30,729,422 probably benign Het
Tmem220 A G 11: 67,034,107 probably null Het
Uspl1 A G 5: 149,188,346 N35S possibly damaging Het
Vmn2r121 T G X: 124,127,894 I810L probably damaging Het
Wbp2nl A T 15: 82,305,744 T46S possibly damaging Het
Zfp955b T A 17: 33,300,966 M57K probably benign Het
Other mutations in Vmn1r170
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02005:Vmn1r170 APN 7 23606913 missense probably damaging 1.00
IGL02150:Vmn1r170 APN 7 23607040 nonsense probably null
IGL02216:Vmn1r170 APN 7 23606490 missense probably damaging 1.00
IGL02749:Vmn1r170 APN 7 23606291 missense probably benign 0.00
IGL02807:Vmn1r170 APN 7 23606335 missense probably damaging 1.00
IGL02828:Vmn1r170 APN 7 23606518 missense probably damaging 0.99
IGL03073:Vmn1r170 APN 7 23606848 missense probably damaging 1.00
IGL03151:Vmn1r170 APN 7 23606577 missense probably benign 0.35
R0079:Vmn1r170 UTSW 7 23606310 missense possibly damaging 0.95
R0266:Vmn1r170 UTSW 7 23606481 missense probably benign 0.00
R0980:Vmn1r170 UTSW 7 23606334 missense possibly damaging 0.81
R1345:Vmn1r170 UTSW 7 23606362 missense probably benign 0.00
R1620:Vmn1r170 UTSW 7 23606329 missense probably benign 0.30
R1713:Vmn1r170 UTSW 7 23606863 missense probably benign 0.30
R1745:Vmn1r170 UTSW 7 23606334 missense probably damaging 0.98
R1974:Vmn1r170 UTSW 7 23606481 missense probably benign 0.00
R2163:Vmn1r170 UTSW 7 23607037 missense probably damaging 1.00
R3812:Vmn1r170 UTSW 7 23606292 missense probably damaging 1.00
R4583:Vmn1r170 UTSW 7 23606662 missense probably benign 0.25
R5309:Vmn1r170 UTSW 7 23606455 missense probably damaging 0.97
R5378:Vmn1r170 UTSW 7 23606538 missense probably benign 0.00
R5379:Vmn1r170 UTSW 7 23606629 missense possibly damaging 0.81
R5661:Vmn1r170 UTSW 7 23606806 missense possibly damaging 0.82
R5673:Vmn1r170 UTSW 7 23606205 missense possibly damaging 0.58
R6181:Vmn1r170 UTSW 7 23606267 missense probably damaging 0.98
R6192:Vmn1r170 UTSW 7 23606509 missense probably damaging 1.00
R7467:Vmn1r170 UTSW 7 23606895 missense not run
R7667:Vmn1r170 UTSW 7 23607048 missense probably damaging 1.00
X0060:Vmn1r170 UTSW 7 23606943 missense possibly damaging 0.50
Z1176:Vmn1r170 UTSW 7 23606410 missense possibly damaging 0.89
Posted On2015-12-18