Incidental Mutation 'R4765:Tnrc6c'
| ID |
366079 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnrc6c
|
| Ensembl Gene |
ENSMUSG00000025571 |
| Gene Name |
trinucleotide repeat containing 6C |
| Synonyms |
9930033H14Rik |
| MMRRC Submission |
042406-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4765 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
117654289-117763439 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 117742927 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Valine
at position 1284
(I1284V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101951
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000026658]
[ENSMUST00000106344]
[ENSMUST00000138299]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000026658
AA Change: I1284V
PolyPhen 2
Score 0.092 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000026658
Gene: ENSMUSG00000025571
AA Change: I1284V
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
32 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
248 |
257 |
N/A |
INTRINSIC |
|
low complexity region
|
298 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
394 |
408 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
457 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
472 |
573 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
594 |
614 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
632 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
639 |
704 |
5.49e-5 |
PROSPERO |
|
internal_repeat_1
|
799 |
902 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
964 |
981 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
991 |
1051 |
5.49e-5 |
PROSPERO |
|
low complexity region
|
1063 |
1079 |
N/A |
INTRINSIC |
|
low complexity region
|
1111 |
1125 |
N/A |
INTRINSIC |
|
UBA
|
1145 |
1182 |
3.68e-4 |
SMART |
|
Pfam:M_domain
|
1232 |
1459 |
6.8e-77 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1468 |
1646 |
4.1e-75 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1643 |
1722 |
3.7e-33 |
PFAM |
|
RRM
|
1725 |
1792 |
1.81e-2 |
SMART |
|
low complexity region
|
1813 |
1823 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106344
AA Change: I1284V
PolyPhen 2
Score 0.092 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000101951
Gene: ENSMUSG00000025571
AA Change: I1284V
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
32 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
248 |
257 |
N/A |
INTRINSIC |
|
low complexity region
|
298 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
394 |
408 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
457 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
472 |
573 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
594 |
614 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
632 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
639 |
704 |
5.49e-5 |
PROSPERO |
|
internal_repeat_1
|
799 |
902 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
964 |
981 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
991 |
1051 |
5.49e-5 |
PROSPERO |
|
low complexity region
|
1063 |
1079 |
N/A |
INTRINSIC |
|
low complexity region
|
1111 |
1125 |
N/A |
INTRINSIC |
|
UBA
|
1145 |
1182 |
3.68e-4 |
SMART |
|
Pfam:M_domain
|
1232 |
1459 |
6.8e-77 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1468 |
1646 |
4.1e-75 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1643 |
1722 |
3.7e-33 |
PFAM |
|
RRM
|
1725 |
1792 |
1.81e-2 |
SMART |
|
low complexity region
|
1813 |
1823 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000138299
AA Change: I1116V
PolyPhen 2
Score 0.021 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000115221
Gene: ENSMUSG00000025571
AA Change: I1116V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
88 |
97 |
N/A |
INTRINSIC |
|
low complexity region
|
138 |
158 |
N/A |
INTRINSIC |
|
low complexity region
|
234 |
248 |
N/A |
INTRINSIC |
|
low complexity region
|
280 |
297 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
312 |
413 |
9.45e-5 |
PROSPERO |
|
low complexity region
|
434 |
454 |
N/A |
INTRINSIC |
|
low complexity region
|
461 |
472 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
639 |
742 |
9.45e-5 |
PROSPERO |
|
low complexity region
|
804 |
821 |
N/A |
INTRINSIC |
|
low complexity region
|
903 |
919 |
N/A |
INTRINSIC |
|
low complexity region
|
951 |
965 |
N/A |
INTRINSIC |
|
UBA
|
985 |
1022 |
3.68e-4 |
SMART |
|
Pfam:M_domain
|
1036 |
1293 |
1.7e-53 |
PFAM |
|
low complexity region
|
1397 |
1406 |
N/A |
INTRINSIC |
|
PDB:3KTP|B
|
1422 |
1443 |
7e-7 |
PDB |
|
low complexity region
|
1507 |
1518 |
N/A |
INTRINSIC |
|
low complexity region
|
1531 |
1552 |
N/A |
INTRINSIC |
|
RRM
|
1557 |
1624 |
1.81e-2 |
SMART |
|
low complexity region
|
1645 |
1655 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140347
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141115
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.1%
- 20x: 95.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap allele exhibit complete neonatal lethality with cyanosis, respiratory distress and thickened mesenchyme in air sacs. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810021J22Rik |
C |
T |
11: 58,881,161 (GRCm38) |
R490C |
probably benign |
Het |
| Abcb11 |
A |
T |
2: 69,245,867 (GRCm38) |
F1166I |
probably damaging |
Het |
| Acta2 |
T |
C |
19: 34,246,152 (GRCm38) |
D181G |
probably damaging |
Het |
| Adgrv1 |
A |
G |
13: 81,106,919 (GRCm38) |
I6195T |
probably damaging |
Het |
| Afg3l2 |
G |
T |
18: 67,421,259 (GRCm38) |
L458M |
probably damaging |
Het |
| Ankfy1 |
T |
G |
11: 72,712,291 (GRCm38) |
S49A |
probably benign |
Het |
| Azi2 |
A |
T |
9: 118,061,471 (GRCm38) |
|
probably benign |
Het |
| Bend3 |
A |
T |
10: 43,510,750 (GRCm38) |
S380C |
probably damaging |
Het |
| Bicc1 |
T |
C |
10: 70,940,593 (GRCm38) |
T759A |
probably damaging |
Het |
| Cdh10 |
G |
T |
15: 19,013,278 (GRCm38) |
V655L |
probably damaging |
Het |
| Cdkn2aip |
C |
A |
8: 47,713,547 (GRCm38) |
W75L |
probably damaging |
Het |
| Cenpj |
G |
A |
14: 56,549,545 (GRCm38) |
R192* |
probably null |
Het |
| Cflar |
T |
C |
1: 58,732,321 (GRCm38) |
S203P |
probably damaging |
Het |
| Chd6 |
A |
T |
2: 160,966,244 (GRCm38) |
C1683* |
probably null |
Het |
| Cpsf2 |
A |
G |
12: 101,997,440 (GRCm38) |
Y476C |
probably damaging |
Het |
| Cyp4a12a |
A |
G |
4: 115,326,191 (GRCm38) |
D169G |
possibly damaging |
Het |
| D430041D05Rik |
T |
A |
2: 104,214,096 (GRCm38) |
R1536S |
probably damaging |
Het |
| Depdc5 |
A |
C |
5: 32,937,635 (GRCm38) |
D752A |
probably damaging |
Het |
| Dnah9 |
C |
T |
11: 65,927,726 (GRCm38) |
G78D |
probably damaging |
Het |
| Drc1 |
G |
T |
5: 30,348,731 (GRCm38) |
Q249H |
probably benign |
Het |
| Drg1 |
T |
C |
11: 3,250,280 (GRCm38) |
I364V |
probably benign |
Het |
| Dtymk |
T |
C |
1: 93,792,909 (GRCm38) |
H130R |
probably damaging |
Het |
| Elac2 |
T |
G |
11: 64,992,222 (GRCm38) |
F140V |
probably damaging |
Het |
| Enpp2 |
A |
G |
15: 54,875,672 (GRCm38) |
V353A |
possibly damaging |
Het |
| Fat2 |
T |
C |
11: 55,281,187 (GRCm38) |
D2900G |
probably damaging |
Het |
| Fermt2 |
G |
T |
14: 45,462,236 (GRCm38) |
T536K |
probably benign |
Het |
| Foxj2 |
G |
T |
6: 122,833,271 (GRCm38) |
Q196H |
probably benign |
Het |
| Gadl1 |
A |
G |
9: 115,966,313 (GRCm38) |
K328R |
probably null |
Het |
| Gata6 |
A |
G |
18: 11,054,394 (GRCm38) |
T108A |
probably benign |
Het |
| Gm16503 |
G |
T |
4: 147,541,097 (GRCm38) |
G16V |
unknown |
Het |
| Gpr37 |
T |
G |
6: 25,669,108 (GRCm38) |
E579A |
probably damaging |
Het |
| Gps2 |
T |
C |
11: 69,916,361 (GRCm38) |
|
probably benign |
Het |
| Hcn4 |
A |
T |
9: 58,857,977 (GRCm38) |
I581F |
unknown |
Het |
| Hfm1 |
T |
A |
5: 106,842,539 (GRCm38) |
Y1335F |
probably benign |
Het |
| Igsf10 |
A |
T |
3: 59,329,705 (GRCm38) |
S1018R |
probably benign |
Het |
| Katnal2 |
C |
T |
18: 76,977,543 (GRCm38) |
|
probably null |
Het |
| Kctd8 |
T |
C |
5: 69,340,848 (GRCm38) |
K152E |
possibly damaging |
Het |
| Lrp8 |
T |
C |
4: 107,854,395 (GRCm38) |
C459R |
probably damaging |
Het |
| Ly6l |
A |
T |
15: 75,449,694 (GRCm38) |
I48L |
probably benign |
Het |
| Megf10 |
A |
T |
18: 57,287,794 (GRCm38) |
I835F |
possibly damaging |
Het |
| Mei1 |
A |
T |
15: 82,112,485 (GRCm38) |
I946F |
possibly damaging |
Het |
| Mrtfb |
C |
A |
16: 13,412,594 (GRCm38) |
P1048T |
probably damaging |
Het |
| Myo7b |
G |
C |
18: 31,961,900 (GRCm38) |
L1881V |
probably benign |
Het |
| Nfkbiz |
T |
C |
16: 55,819,024 (GRCm38) |
|
probably null |
Het |
| Or4b13 |
T |
A |
2: 90,252,463 (GRCm38) |
Y175F |
probably damaging |
Het |
| Or5b24 |
T |
C |
19: 12,935,076 (GRCm38) |
C113R |
possibly damaging |
Het |
| Pcdhgc5 |
T |
C |
18: 37,822,069 (GRCm38) |
S799P |
probably benign |
Het |
| Plk4 |
A |
G |
3: 40,802,022 (GRCm38) |
E97G |
probably damaging |
Het |
| Pole2 |
A |
T |
12: 69,222,052 (GRCm38) |
H114Q |
possibly damaging |
Het |
| Rad9a |
C |
A |
19: 4,200,489 (GRCm38) |
V109L |
probably benign |
Het |
| Scn8a |
A |
G |
15: 101,040,471 (GRCm38) |
H1917R |
probably benign |
Het |
| Scyl2 |
C |
T |
10: 89,659,298 (GRCm38) |
V304I |
probably damaging |
Het |
| Serpina3f |
G |
C |
12: 104,219,431 (GRCm38) |
E298D |
probably benign |
Het |
| Shoc2 |
A |
G |
19: 53,988,303 (GRCm38) |
E208G |
probably benign |
Het |
| Sin3a |
G |
A |
9: 57,096,803 (GRCm38) |
V280I |
probably benign |
Het |
| Slc26a2 |
A |
T |
18: 61,199,486 (GRCm38) |
I291N |
probably damaging |
Het |
| Slc4a7 |
T |
G |
14: 14,762,414 (GRCm38) |
D600E |
probably damaging |
Het |
| Slc5a6 |
A |
T |
5: 31,038,083 (GRCm38) |
F430L |
possibly damaging |
Het |
| Snx19 |
A |
C |
9: 30,440,157 (GRCm38) |
Q840H |
probably damaging |
Het |
| Spast |
C |
A |
17: 74,369,216 (GRCm38) |
D340E |
probably damaging |
Het |
| Sprr4 |
G |
A |
3: 92,500,409 (GRCm38) |
P29S |
unknown |
Het |
| Stk11ip |
T |
G |
1: 75,527,155 (GRCm38) |
L239R |
probably damaging |
Het |
| Thoc6 |
A |
G |
17: 23,670,888 (GRCm38) |
L20P |
probably damaging |
Het |
| Tnfrsf8 |
A |
T |
4: 145,296,877 (GRCm38) |
S129T |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,772,507 (GRCm38) |
Y16711C |
probably damaging |
Het |
| Ttn |
A |
G |
2: 76,710,987 (GRCm38) |
L33885P |
probably damaging |
Het |
| Ubn2 |
T |
A |
6: 38,479,140 (GRCm38) |
C501S |
probably damaging |
Het |
| Ubr1 |
A |
T |
2: 120,963,442 (GRCm38) |
L87* |
probably null |
Het |
| Uhmk1 |
T |
C |
1: 170,199,901 (GRCm38) |
Y320C |
probably damaging |
Het |
| Vldlr |
T |
C |
19: 27,240,547 (GRCm38) |
V465A |
probably damaging |
Het |
| Vmn1r1 |
C |
T |
1: 182,157,906 (GRCm38) |
A65T |
probably benign |
Het |
| Vmn2r25 |
C |
T |
6: 123,823,223 (GRCm38) |
C720Y |
probably damaging |
Het |
| Xrra1 |
T |
C |
7: 99,906,568 (GRCm38) |
Y381H |
probably benign |
Het |
| Zfhx4 |
T |
C |
3: 5,400,152 (GRCm38) |
L1790P |
probably benign |
Het |
| Zscan4d |
T |
A |
7: 11,162,667 (GRCm38) |
M259L |
probably benign |
Het |
|
| Other mutations in Tnrc6c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00839:Tnrc6c
|
APN |
11 |
117,714,185 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
IGL01013:Tnrc6c
|
APN |
11 |
117,722,029 (GRCm38) |
missense |
probably benign |
0.44 |
|
IGL01092:Tnrc6c
|
APN |
11 |
117,721,985 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01383:Tnrc6c
|
APN |
11 |
117,714,257 (GRCm38) |
missense |
probably benign |
0.37 |
|
IGL01395:Tnrc6c
|
APN |
11 |
117,723,113 (GRCm38) |
missense |
probably benign |
0.08 |
|
IGL01726:Tnrc6c
|
APN |
11 |
117,749,335 (GRCm38) |
splice site |
probably benign |
|
|
IGL01869:Tnrc6c
|
APN |
11 |
117,755,448 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
IGL02108:Tnrc6c
|
APN |
11 |
117,721,199 (GRCm38) |
missense |
probably benign |
0.29 |
|
IGL02457:Tnrc6c
|
APN |
11 |
117,722,977 (GRCm38) |
missense |
probably benign |
0.28 |
|
IGL02612:Tnrc6c
|
APN |
11 |
117,743,000 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
IGL02748:Tnrc6c
|
APN |
11 |
117,732,170 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03160:Tnrc6c
|
APN |
11 |
117,749,825 (GRCm38) |
splice site |
probably benign |
|
|
rodion
|
UTSW |
11 |
117,738,350 (GRCm38) |
critical splice donor site |
probably null |
|
|
F5770:Tnrc6c
|
UTSW |
11 |
117,723,326 (GRCm38) |
missense |
probably damaging |
1.00 |
|
K3955:Tnrc6c
|
UTSW |
11 |
117,760,738 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0015:Tnrc6c
|
UTSW |
11 |
117,721,458 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0143:Tnrc6c
|
UTSW |
11 |
117,752,985 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0277:Tnrc6c
|
UTSW |
11 |
117,739,881 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0323:Tnrc6c
|
UTSW |
11 |
117,739,881 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0464:Tnrc6c
|
UTSW |
11 |
117,760,549 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0699:Tnrc6c
|
UTSW |
11 |
117,722,621 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1015:Tnrc6c
|
UTSW |
11 |
117,721,922 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R1201:Tnrc6c
|
UTSW |
11 |
117,721,674 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1297:Tnrc6c
|
UTSW |
11 |
117,733,703 (GRCm38) |
missense |
possibly damaging |
0.52 |
|
R1560:Tnrc6c
|
UTSW |
11 |
117,759,637 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1596:Tnrc6c
|
UTSW |
11 |
117,758,041 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1758:Tnrc6c
|
UTSW |
11 |
117,760,730 (GRCm38) |
missense |
probably benign |
0.09 |
|
R1892:Tnrc6c
|
UTSW |
11 |
117,714,362 (GRCm38) |
missense |
probably benign |
|
|
R1901:Tnrc6c
|
UTSW |
11 |
117,723,005 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1935:Tnrc6c
|
UTSW |
11 |
117,756,023 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R1936:Tnrc6c
|
UTSW |
11 |
117,756,023 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R1937:Tnrc6c
|
UTSW |
11 |
117,756,023 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R1940:Tnrc6c
|
UTSW |
11 |
117,756,023 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R3622:Tnrc6c
|
UTSW |
11 |
117,749,625 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3711:Tnrc6c
|
UTSW |
11 |
117,723,124 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3725:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3775:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3776:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3836:Tnrc6c
|
UTSW |
11 |
117,723,229 (GRCm38) |
missense |
probably benign |
0.20 |
|
R3844:Tnrc6c
|
UTSW |
11 |
117,755,483 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3852:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3928:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3929:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3937:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R3943:Tnrc6c
|
UTSW |
11 |
117,723,529 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4501:Tnrc6c
|
UTSW |
11 |
117,722,498 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4510:Tnrc6c
|
UTSW |
11 |
117,742,958 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R4511:Tnrc6c
|
UTSW |
11 |
117,742,958 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R4654:Tnrc6c
|
UTSW |
11 |
117,720,971 (GRCm38) |
missense |
probably benign |
|
|
R4824:Tnrc6c
|
UTSW |
11 |
117,722,905 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5004:Tnrc6c
|
UTSW |
11 |
117,721,046 (GRCm38) |
missense |
probably benign |
0.44 |
|
R5094:Tnrc6c
|
UTSW |
11 |
117,721,046 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5130:Tnrc6c
|
UTSW |
11 |
117,738,350 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5234:Tnrc6c
|
UTSW |
11 |
117,760,729 (GRCm38) |
missense |
probably benign |
0.42 |
|
R5235:Tnrc6c
|
UTSW |
11 |
117,760,729 (GRCm38) |
missense |
probably benign |
0.42 |
|
R5345:Tnrc6c
|
UTSW |
11 |
117,723,287 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R5359:Tnrc6c
|
UTSW |
11 |
117,758,905 (GRCm38) |
splice site |
silent |
|
|
R5428:Tnrc6c
|
UTSW |
11 |
117,700,762 (GRCm38) |
start codon destroyed |
probably null |
|
|
R5548:Tnrc6c
|
UTSW |
11 |
117,760,843 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
R5587:Tnrc6c
|
UTSW |
11 |
117,749,271 (GRCm38) |
nonsense |
probably null |
|
|
R5875:Tnrc6c
|
UTSW |
11 |
117,759,708 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5947:Tnrc6c
|
UTSW |
11 |
117,722,519 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6135:Tnrc6c
|
UTSW |
11 |
117,736,005 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R6354:Tnrc6c
|
UTSW |
11 |
117,749,614 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R6389:Tnrc6c
|
UTSW |
11 |
117,722,741 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7027:Tnrc6c
|
UTSW |
11 |
117,733,618 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7048:Tnrc6c
|
UTSW |
11 |
117,721,974 (GRCm38) |
missense |
probably benign |
0.41 |
|
R7098:Tnrc6c
|
UTSW |
11 |
117,714,126 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7315:Tnrc6c
|
UTSW |
11 |
117,723,528 (GRCm38) |
missense |
probably benign |
0.11 |
|
R7378:Tnrc6c
|
UTSW |
11 |
117,741,780 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7386:Tnrc6c
|
UTSW |
11 |
117,721,954 (GRCm38) |
missense |
probably benign |
|
|
R7515:Tnrc6c
|
UTSW |
11 |
117,741,681 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7665:Tnrc6c
|
UTSW |
11 |
117,720,951 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R7755:Tnrc6c
|
UTSW |
11 |
117,758,086 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8679:Tnrc6c
|
UTSW |
11 |
117,714,135 (GRCm38) |
missense |
probably benign |
|
|
R8824:Tnrc6c
|
UTSW |
11 |
117,739,854 (GRCm38) |
splice site |
probably benign |
|
|
R8971:Tnrc6c
|
UTSW |
11 |
117,749,263 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R9261:Tnrc6c
|
UTSW |
11 |
117,714,279 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9283:Tnrc6c
|
UTSW |
11 |
117,700,804 (GRCm38) |
missense |
unknown |
|
|
R9342:Tnrc6c
|
UTSW |
11 |
117,739,894 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9633:Tnrc6c
|
UTSW |
11 |
117,747,183 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9761:Tnrc6c
|
UTSW |
11 |
117,732,310 (GRCm38) |
missense |
probably benign |
|
|
V7580:Tnrc6c
|
UTSW |
11 |
117,723,326 (GRCm38) |
missense |
probably damaging |
1.00 |
|
V7581:Tnrc6c
|
UTSW |
11 |
117,723,326 (GRCm38) |
missense |
probably damaging |
1.00 |
|
V7582:Tnrc6c
|
UTSW |
11 |
117,723,326 (GRCm38) |
missense |
probably damaging |
1.00 |
|
V7583:Tnrc6c
|
UTSW |
11 |
117,723,326 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Tnrc6c
|
UTSW |
11 |
117,732,177 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTAACTGTGACAGCCGTGTTTAG -3'
(R):5'- ACCAAGTACAGTGTGCAAAGC -3'
Sequencing Primer
(F):5'- TGACAGCCGTGTTTAGGGACAC -3'
(R):5'- GCAAAGCTTATTGTTCGGACC -3'
|
| Posted On |
2015-12-21 |
Incidental Mutation