Incidental Mutation 'R4780:Myh15'
| ID |
366452 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh15
|
| Ensembl Gene |
ENSMUSG00000092009 |
| Gene Name |
myosin, heavy chain 15 |
| Synonyms |
EG667772 |
| MMRRC Submission |
041993-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.149)
|
| Stock # |
R4780 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
48877849-49019467 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 48940420 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Threonine
at position 790
(I790T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000127539
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000168680]
|
| AlphaFold |
E9Q264 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168680
AA Change: I790T
PolyPhen 2
Score 0.131 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000127539
Gene: ENSMUSG00000092009
AA Change: I790T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
30 |
70 |
5.2e-12 |
PFAM |
|
MYSc
|
76 |
770 |
N/A |
SMART |
|
Pfam:Myosin_tail_1
|
836 |
1915 |
9.5e-118 |
PFAM |
|
| Meta Mutation Damage Score |
0.0658 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.6%
|
| Validation Efficiency |
98% (107/109) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110002E22Rik |
A |
G |
3: 137,771,131 (GRCm39) |
N107D |
probably benign |
Het |
| 4833413E03Rik |
A |
C |
17: 31,777,738 (GRCm39) |
|
noncoding transcript |
Het |
| 4931429L15Rik |
G |
T |
9: 46,220,144 (GRCm39) |
H129Q |
possibly damaging |
Het |
| A730018C14Rik |
A |
G |
12: 112,382,069 (GRCm39) |
|
noncoding transcript |
Het |
| Abcc6 |
T |
A |
7: 45,646,115 (GRCm39) |
K791N |
probably benign |
Het |
| Adcy4 |
T |
G |
14: 56,012,493 (GRCm39) |
Q550P |
probably benign |
Het |
| Add3 |
C |
A |
19: 53,223,223 (GRCm39) |
A325E |
possibly damaging |
Het |
| Agbl4 |
T |
A |
4: 111,514,528 (GRCm39) |
I513N |
possibly damaging |
Het |
| Agfg1 |
C |
A |
1: 82,864,108 (GRCm39) |
T392K |
probably damaging |
Het |
| Akna |
C |
A |
4: 63,297,491 (GRCm39) |
M854I |
probably benign |
Het |
| Ankrd44 |
T |
C |
1: 54,802,916 (GRCm39) |
N194S |
probably benign |
Het |
| Anks1b |
A |
G |
10: 89,709,594 (GRCm39) |
K21E |
probably damaging |
Het |
| Ap1s3 |
A |
G |
1: 79,586,889 (GRCm39) |
F154L |
probably benign |
Het |
| Apbb2 |
T |
A |
5: 66,520,160 (GRCm39) |
N477I |
probably damaging |
Het |
| Apobec3 |
T |
C |
15: 79,783,225 (GRCm39) |
C101R |
possibly damaging |
Het |
| Arnt |
G |
T |
3: 95,395,696 (GRCm39) |
V410F |
probably damaging |
Het |
| Arsg |
G |
A |
11: 109,424,839 (GRCm39) |
R270H |
possibly damaging |
Het |
| B3gnt7 |
T |
A |
1: 86,232,992 (GRCm39) |
D79E |
probably damaging |
Het |
| Cd44 |
G |
T |
2: 102,691,910 (GRCm39) |
A126D |
probably damaging |
Het |
| Cd69 |
A |
G |
6: 129,248,318 (GRCm39) |
I56T |
probably damaging |
Het |
| Cep120 |
G |
A |
18: 53,857,608 (GRCm39) |
P286S |
probably benign |
Het |
| Ces2a |
T |
C |
8: 105,463,840 (GRCm39) |
F184S |
probably damaging |
Het |
| Chrng |
A |
G |
1: 87,135,246 (GRCm39) |
N185S |
probably damaging |
Het |
| Cldn6 |
A |
T |
17: 23,900,221 (GRCm39) |
M62L |
probably benign |
Het |
| Cntn6 |
T |
A |
6: 104,822,745 (GRCm39) |
N765K |
probably damaging |
Het |
| Cspg4b |
A |
G |
13: 113,454,392 (GRCm39) |
Y146C |
probably damaging |
Het |
| Ctnnal1 |
T |
C |
4: 56,847,857 (GRCm39) |
D94G |
probably damaging |
Het |
| Cyp2c69 |
T |
C |
19: 39,866,038 (GRCm39) |
N185S |
probably benign |
Het |
| Depdc1a |
A |
G |
3: 159,232,343 (GRCm39) |
N698S |
probably benign |
Het |
| Dnah2 |
A |
T |
11: 69,364,697 (GRCm39) |
I1986N |
probably damaging |
Het |
| Dnah7b |
A |
G |
1: 46,392,174 (GRCm39) |
E3845G |
probably benign |
Het |
| Dpysl3 |
C |
T |
18: 43,487,867 (GRCm39) |
V159I |
probably benign |
Het |
| Dync1h1 |
T |
C |
12: 110,627,630 (GRCm39) |
Y4047H |
probably damaging |
Het |
| E130308A19Rik |
C |
T |
4: 59,691,057 (GRCm39) |
P297L |
probably benign |
Het |
| E2f5 |
A |
G |
3: 14,652,379 (GRCm39) |
T72A |
probably benign |
Het |
| Ephb6 |
G |
T |
6: 41,593,073 (GRCm39) |
R437L |
probably damaging |
Het |
| Erbb4 |
T |
C |
1: 68,337,473 (GRCm39) |
H615R |
probably damaging |
Het |
| Erbin |
T |
C |
13: 104,020,714 (GRCm39) |
T82A |
probably damaging |
Het |
| Eri2 |
T |
C |
7: 119,384,903 (GRCm39) |
N533D |
probably benign |
Het |
| Fkbp9 |
A |
G |
6: 56,827,701 (GRCm39) |
N174S |
probably damaging |
Het |
| Fsbp |
C |
T |
4: 11,583,709 (GRCm39) |
T136I |
possibly damaging |
Het |
| Fubp3 |
C |
A |
2: 31,473,223 (GRCm39) |
D47E |
probably damaging |
Het |
| Gm21850 |
G |
A |
2: 153,898,419 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5141 |
T |
A |
13: 62,922,764 (GRCm39) |
Y135F |
unknown |
Het |
| Gm7353 |
T |
A |
7: 3,160,725 (GRCm39) |
|
noncoding transcript |
Het |
| Gm9925 |
T |
C |
18: 74,198,344 (GRCm39) |
|
probably benign |
Het |
| Greb1l |
T |
C |
18: 10,541,792 (GRCm39) |
S1180P |
probably benign |
Het |
| H2ac11 |
G |
A |
13: 22,227,079 (GRCm39) |
Q7* |
probably null |
Het |
| Ift70a2 |
A |
C |
2: 75,807,920 (GRCm39) |
C197W |
probably benign |
Het |
| Kiz |
A |
G |
2: 146,731,166 (GRCm39) |
T192A |
possibly damaging |
Het |
| Klhl24 |
T |
A |
16: 19,925,708 (GRCm39) |
C79S |
probably damaging |
Het |
| Map3k11 |
A |
G |
19: 5,740,966 (GRCm39) |
H231R |
probably damaging |
Het |
| Mbd4 |
C |
A |
6: 115,826,345 (GRCm39) |
R194S |
probably benign |
Het |
| Mettl21e |
A |
C |
1: 44,250,303 (GRCm39) |
S34R |
probably benign |
Het |
| Mrps5 |
T |
C |
2: 127,440,161 (GRCm39) |
V245A |
probably benign |
Het |
| Mtrf1 |
T |
C |
14: 79,639,128 (GRCm39) |
Y87H |
probably benign |
Het |
| Necab1 |
T |
G |
4: 14,989,248 (GRCm39) |
I176L |
probably benign |
Het |
| Nfkb2 |
T |
A |
19: 46,298,361 (GRCm39) |
L555Q |
probably damaging |
Het |
| Nhlrc3 |
T |
A |
3: 53,365,988 (GRCm39) |
E168D |
probably benign |
Het |
| Nlrp5 |
T |
A |
7: 23,135,203 (GRCm39) |
C949S |
probably damaging |
Het |
| Nup155 |
C |
A |
15: 8,187,187 (GRCm39) |
A1372E |
probably benign |
Het |
| Nynrin |
G |
T |
14: 56,100,720 (GRCm39) |
R170L |
probably damaging |
Het |
| Ogfrl1 |
T |
A |
1: 23,409,402 (GRCm39) |
N275Y |
probably damaging |
Het |
| Olr1 |
A |
T |
6: 129,465,839 (GRCm39) |
S56T |
probably damaging |
Het |
| Or4k52 |
A |
G |
2: 111,611,190 (GRCm39) |
D175G |
probably damaging |
Het |
| Or5aq1 |
C |
T |
2: 86,966,221 (GRCm39) |
S148N |
probably damaging |
Het |
| Or5b121 |
A |
G |
19: 13,507,319 (GRCm39) |
N138S |
probably benign |
Het |
| Or8b48 |
A |
G |
9: 38,493,265 (GRCm39) |
T231A |
possibly damaging |
Het |
| Ovol2 |
A |
T |
2: 144,173,203 (GRCm39) |
|
probably benign |
Het |
| Pcdha6 |
A |
T |
18: 37,102,906 (GRCm39) |
I700F |
probably damaging |
Het |
| Prkcz |
C |
T |
4: 155,374,159 (GRCm39) |
V86M |
probably damaging |
Het |
| Ptpn13 |
A |
G |
5: 103,734,639 (GRCm39) |
T2124A |
probably benign |
Het |
| Ranbp3 |
G |
T |
17: 56,980,346 (GRCm39) |
|
probably benign |
Het |
| Rapgef2 |
A |
G |
3: 79,077,076 (GRCm39) |
|
probably benign |
Het |
| Rbl1 |
A |
G |
2: 157,016,724 (GRCm39) |
V625A |
probably benign |
Het |
| Rbm38 |
G |
T |
2: 172,863,944 (GRCm39) |
G38C |
probably damaging |
Het |
| Reg1 |
T |
G |
6: 78,403,333 (GRCm39) |
F7C |
possibly damaging |
Het |
| Retnlg |
A |
T |
16: 48,694,697 (GRCm39) |
Q115L |
possibly damaging |
Het |
| Rhobtb1 |
G |
A |
10: 69,105,983 (GRCm39) |
V183I |
probably benign |
Het |
| Rims1 |
T |
C |
1: 22,361,329 (GRCm39) |
Q1186R |
probably damaging |
Het |
| Ryr1 |
A |
G |
7: 28,794,522 (GRCm39) |
F1246L |
possibly damaging |
Het |
| Samm50 |
A |
G |
15: 84,094,811 (GRCm39) |
N401S |
possibly damaging |
Het |
| Scn3a |
T |
A |
2: 65,336,537 (GRCm39) |
I690F |
probably damaging |
Het |
| Sdk1 |
A |
G |
5: 141,944,993 (GRCm39) |
D304G |
probably damaging |
Het |
| Skint6 |
T |
C |
4: 113,093,594 (GRCm39) |
Y183C |
probably damaging |
Het |
| Slamf1 |
A |
T |
1: 171,604,829 (GRCm39) |
T200S |
probably benign |
Het |
| Slc34a2 |
C |
T |
5: 53,226,793 (GRCm39) |
R639C |
probably damaging |
Het |
| Smap1 |
A |
T |
1: 23,892,517 (GRCm39) |
M149K |
probably benign |
Het |
| Sorcs1 |
T |
C |
19: 50,132,419 (GRCm39) |
|
probably benign |
Het |
| Sp140 |
T |
A |
1: 85,538,549 (GRCm39) |
D95E |
possibly damaging |
Het |
| Spata13 |
G |
A |
14: 60,991,356 (GRCm39) |
W366* |
probably null |
Het |
| Spata31e4 |
C |
A |
13: 50,855,116 (GRCm39) |
S251R |
probably damaging |
Het |
| Strip1 |
G |
A |
3: 107,534,314 (GRCm39) |
T136I |
probably benign |
Het |
| Tacr1 |
A |
T |
6: 82,534,053 (GRCm39) |
T360S |
probably benign |
Het |
| Tbc1d14 |
T |
A |
5: 36,728,600 (GRCm39) |
|
probably benign |
Het |
| Tcaf2 |
T |
C |
6: 42,604,996 (GRCm39) |
Y596C |
probably damaging |
Het |
| Tspoap1 |
C |
T |
11: 87,669,269 (GRCm39) |
T1454I |
possibly damaging |
Het |
| Ttn |
A |
T |
2: 76,744,927 (GRCm39) |
M5374K |
probably benign |
Het |
| Uts2r |
G |
A |
11: 121,051,705 (GRCm39) |
V190I |
possibly damaging |
Het |
| Vmn1r181 |
A |
G |
7: 23,684,008 (GRCm39) |
T158A |
possibly damaging |
Het |
| Wdr35 |
A |
T |
12: 9,068,150 (GRCm39) |
T778S |
probably benign |
Het |
| Xrn1 |
A |
T |
9: 95,856,797 (GRCm39) |
|
probably benign |
Het |
| Zfp35 |
A |
T |
18: 24,136,326 (GRCm39) |
K223N |
probably damaging |
Het |
| Zfp764 |
T |
C |
7: 127,003,943 (GRCm39) |
Q396R |
probably benign |
Het |
| Zfyve1 |
T |
C |
12: 83,605,421 (GRCm39) |
Y11C |
probably damaging |
Het |
|
| Other mutations in Myh15 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00943:Myh15
|
APN |
16 |
48,986,176 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01095:Myh15
|
APN |
16 |
48,952,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01343:Myh15
|
APN |
16 |
48,976,040 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01474:Myh15
|
APN |
16 |
48,952,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01572:Myh15
|
APN |
16 |
48,920,585 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL01595:Myh15
|
APN |
16 |
48,993,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01632:Myh15
|
APN |
16 |
48,881,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01638:Myh15
|
APN |
16 |
48,889,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01667:Myh15
|
APN |
16 |
49,015,942 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL01715:Myh15
|
APN |
16 |
48,877,847 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01833:Myh15
|
APN |
16 |
48,934,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02004:Myh15
|
APN |
16 |
48,930,892 (GRCm39) |
splice site |
probably benign |
|
|
IGL02033:Myh15
|
APN |
16 |
48,965,707 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02148:Myh15
|
APN |
16 |
48,936,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02225:Myh15
|
APN |
16 |
48,911,526 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02249:Myh15
|
APN |
16 |
48,930,847 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02505:Myh15
|
APN |
16 |
48,937,626 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02622:Myh15
|
APN |
16 |
48,997,317 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02814:Myh15
|
APN |
16 |
48,965,801 (GRCm39) |
splice site |
probably benign |
|
|
IGL02869:Myh15
|
APN |
16 |
48,965,767 (GRCm39) |
missense |
probably benign |
|
|
IGL02879:Myh15
|
APN |
16 |
48,993,422 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL02881:Myh15
|
APN |
16 |
48,937,628 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL03077:Myh15
|
APN |
16 |
48,916,901 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL03354:Myh15
|
APN |
16 |
48,992,373 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03411:Myh15
|
APN |
16 |
48,980,330 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
ANU74:Myh15
|
UTSW |
16 |
48,993,295 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
P0027:Myh15
|
UTSW |
16 |
48,901,571 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
PIT1430001:Myh15
|
UTSW |
16 |
49,017,254 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0017:Myh15
|
UTSW |
16 |
48,983,423 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0038:Myh15
|
UTSW |
16 |
48,891,504 (GRCm39) |
splice site |
probably benign |
|
|
R0149:Myh15
|
UTSW |
16 |
48,934,368 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0361:Myh15
|
UTSW |
16 |
48,934,368 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0373:Myh15
|
UTSW |
16 |
49,003,322 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0433:Myh15
|
UTSW |
16 |
48,965,599 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0525:Myh15
|
UTSW |
16 |
48,952,414 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0586:Myh15
|
UTSW |
16 |
48,992,250 (GRCm39) |
splice site |
probably benign |
|
|
R0601:Myh15
|
UTSW |
16 |
48,881,944 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0717:Myh15
|
UTSW |
16 |
48,963,356 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0963:Myh15
|
UTSW |
16 |
48,952,512 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1075:Myh15
|
UTSW |
16 |
48,940,417 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1143:Myh15
|
UTSW |
16 |
48,885,449 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1200:Myh15
|
UTSW |
16 |
48,916,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1644:Myh15
|
UTSW |
16 |
48,952,566 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1646:Myh15
|
UTSW |
16 |
49,015,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1720:Myh15
|
UTSW |
16 |
48,913,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1768:Myh15
|
UTSW |
16 |
48,983,498 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1881:Myh15
|
UTSW |
16 |
48,891,446 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2048:Myh15
|
UTSW |
16 |
48,975,928 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2064:Myh15
|
UTSW |
16 |
48,975,984 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R2184:Myh15
|
UTSW |
16 |
48,957,874 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2212:Myh15
|
UTSW |
16 |
48,959,095 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2216:Myh15
|
UTSW |
16 |
48,986,201 (GRCm39) |
nonsense |
probably null |
|
|
R2321:Myh15
|
UTSW |
16 |
48,933,436 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2327:Myh15
|
UTSW |
16 |
48,963,313 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2395:Myh15
|
UTSW |
16 |
48,889,877 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2399:Myh15
|
UTSW |
16 |
48,957,952 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3413:Myh15
|
UTSW |
16 |
48,959,095 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4234:Myh15
|
UTSW |
16 |
48,983,405 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4382:Myh15
|
UTSW |
16 |
48,963,306 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4421:Myh15
|
UTSW |
16 |
48,929,707 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4580:Myh15
|
UTSW |
16 |
48,885,388 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4657:Myh15
|
UTSW |
16 |
48,992,421 (GRCm39) |
nonsense |
probably null |
|
|
R5004:Myh15
|
UTSW |
16 |
48,952,411 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5175:Myh15
|
UTSW |
16 |
48,889,789 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5189:Myh15
|
UTSW |
16 |
48,921,870 (GRCm39) |
missense |
probably benign |
0.20 |
|
R5311:Myh15
|
UTSW |
16 |
48,986,204 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5318:Myh15
|
UTSW |
16 |
48,930,834 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5404:Myh15
|
UTSW |
16 |
48,980,341 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5415:Myh15
|
UTSW |
16 |
48,937,658 (GRCm39) |
missense |
probably null |
1.00 |
|
R5558:Myh15
|
UTSW |
16 |
48,889,900 (GRCm39) |
missense |
probably benign |
0.32 |
|
R5977:Myh15
|
UTSW |
16 |
48,973,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6004:Myh15
|
UTSW |
16 |
48,980,062 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6275:Myh15
|
UTSW |
16 |
48,965,610 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6381:Myh15
|
UTSW |
16 |
48,921,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6448:Myh15
|
UTSW |
16 |
48,992,295 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6516:Myh15
|
UTSW |
16 |
48,957,996 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6752:Myh15
|
UTSW |
16 |
49,003,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6847:Myh15
|
UTSW |
16 |
48,965,451 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R6868:Myh15
|
UTSW |
16 |
48,889,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6889:Myh15
|
UTSW |
16 |
48,973,474 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6896:Myh15
|
UTSW |
16 |
48,933,434 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6955:Myh15
|
UTSW |
16 |
48,901,598 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6984:Myh15
|
UTSW |
16 |
48,930,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7046:Myh15
|
UTSW |
16 |
48,929,662 (GRCm39) |
nonsense |
probably null |
|
|
R7095:Myh15
|
UTSW |
16 |
48,992,272 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7098:Myh15
|
UTSW |
16 |
48,997,420 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R7134:Myh15
|
UTSW |
16 |
48,901,705 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7159:Myh15
|
UTSW |
16 |
48,881,937 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7244:Myh15
|
UTSW |
16 |
49,017,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7278:Myh15
|
UTSW |
16 |
48,911,468 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7309:Myh15
|
UTSW |
16 |
48,916,828 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7327:Myh15
|
UTSW |
16 |
48,993,369 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7418:Myh15
|
UTSW |
16 |
48,975,900 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7937:Myh15
|
UTSW |
16 |
48,976,009 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8053:Myh15
|
UTSW |
16 |
48,963,302 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8313:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8315:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8316:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8317:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8342:Myh15
|
UTSW |
16 |
48,913,120 (GRCm39) |
missense |
probably benign |
|
|
R8379:Myh15
|
UTSW |
16 |
48,901,551 (GRCm39) |
missense |
probably benign |
|
|
R8445:Myh15
|
UTSW |
16 |
48,940,381 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8707:Myh15
|
UTSW |
16 |
48,973,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8729:Myh15
|
UTSW |
16 |
48,881,851 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8773:Myh15
|
UTSW |
16 |
49,015,900 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8869:Myh15
|
UTSW |
16 |
48,997,366 (GRCm39) |
missense |
probably benign |
|
|
R8890:Myh15
|
UTSW |
16 |
48,959,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9026:Myh15
|
UTSW |
16 |
49,007,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9063:Myh15
|
UTSW |
16 |
48,913,118 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9290:Myh15
|
UTSW |
16 |
48,997,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9630:Myh15
|
UTSW |
16 |
48,980,341 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9710:Myh15
|
UTSW |
16 |
48,959,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0012:Myh15
|
UTSW |
16 |
48,963,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0020:Myh15
|
UTSW |
16 |
48,986,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Myh15
|
UTSW |
16 |
48,916,894 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Myh15
|
UTSW |
16 |
48,980,189 (GRCm39) |
missense |
probably benign |
0.09 |
|
Z1177:Myh15
|
UTSW |
16 |
48,975,981 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Z1177:Myh15
|
UTSW |
16 |
48,901,591 (GRCm39) |
missense |
probably benign |
0.02 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCCAGAGACTATGCCAGTTGTC -3'
(R):5'- TGGGAAGACAGAAAGGTCCTTTATAC -3'
Sequencing Primer
(F):5'- AGACTATGCCAGTTGTCCATGGC -3'
(R):5'- CAGTAGACTAGGCTATGTACC -3'
|
| Posted On |
2015-12-21 |
Incidental Mutation