Incidental Mutation 'R4781:Traf7'
| ID |
366537 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Traf7
|
| Ensembl Gene |
ENSMUSG00000052752 |
| Gene Name |
TNF receptor-associated factor 7 |
| Synonyms |
RFWD1 |
| MMRRC Submission |
042415-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.644)
|
| Stock # |
R4781 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
24727824-24746912 bp(-) (GRCm39) |
| Type of Mutation |
unclassified |
| DNA Base Change (assembly) |
C to G
at 24729412 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000024958]
[ENSMUST00000070777]
[ENSMUST00000088464]
[ENSMUST00000176086]
[ENSMUST00000176178]
[ENSMUST00000176324]
[ENSMUST00000177154]
[ENSMUST00000177193]
[ENSMUST00000176353]
[ENSMUST00000176652]
[ENSMUST00000177401]
[ENSMUST00000176668]
[ENSMUST00000176237]
[ENSMUST00000177025]
[ENSMUST00000177405]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000024958
|
| SMART Domains |
Protein: ENSMUSP00000024958
Gene: ENSMUSG00000033597
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
48 |
77 |
9.93e-5 |
SMART |
|
ANK
|
81 |
110 |
1.9e-1 |
SMART |
|
ANK
|
114 |
143 |
1.51e-4 |
SMART |
|
ANK
|
147 |
176 |
1.15e0 |
SMART |
|
ANK
|
188 |
217 |
2.6e-8 |
SMART |
|
ANK
|
220 |
249 |
3.31e-1 |
SMART |
|
SH3
|
284 |
346 |
3.62e-5 |
SMART |
|
Pfam:Caskin1-CID
|
373 |
421 |
3e-26 |
PFAM |
|
SAM
|
473 |
539 |
3.63e-15 |
SMART |
|
SAM
|
542 |
609 |
5.41e-14 |
SMART |
|
low complexity region
|
631 |
647 |
N/A |
INTRINSIC |
|
low complexity region
|
667 |
679 |
N/A |
INTRINSIC |
|
low complexity region
|
715 |
724 |
N/A |
INTRINSIC |
|
low complexity region
|
841 |
863 |
N/A |
INTRINSIC |
|
Pfam:Caskin-Pro-rich
|
878 |
966 |
3e-37 |
PFAM |
|
low complexity region
|
1163 |
1168 |
N/A |
INTRINSIC |
|
low complexity region
|
1190 |
1216 |
N/A |
INTRINSIC |
|
low complexity region
|
1222 |
1232 |
N/A |
INTRINSIC |
|
low complexity region
|
1269 |
1288 |
N/A |
INTRINSIC |
|
low complexity region
|
1294 |
1312 |
N/A |
INTRINSIC |
|
low complexity region
|
1315 |
1333 |
N/A |
INTRINSIC |
|
low complexity region
|
1344 |
1359 |
N/A |
INTRINSIC |
|
Pfam:Caskin-tail
|
1369 |
1431 |
7.2e-33 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000070777
|
| SMART Domains |
Protein: ENSMUSP00000069334
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
RING
|
92 |
125 |
4.73e-6 |
SMART |
|
coiled coil region
|
264 |
332 |
N/A |
INTRINSIC |
|
WD40
|
344 |
383 |
8.35e-11 |
SMART |
|
WD40
|
387 |
424 |
8.42e-7 |
SMART |
|
WD40
|
427 |
463 |
2.09e-2 |
SMART |
|
WD40
|
468 |
504 |
1.92e0 |
SMART |
|
WD40
|
507 |
544 |
5.15e-2 |
SMART |
|
WD40
|
547 |
588 |
1.78e-5 |
SMART |
|
WD40
|
591 |
628 |
1.63e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000088464
|
| SMART Domains |
Protein: ENSMUSP00000085812
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
90 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
117 |
N/A |
INTRINSIC |
|
RING
|
130 |
163 |
4.73e-6 |
SMART |
|
Pfam:zf-TRAF
|
221 |
277 |
3.4e-8 |
PFAM |
|
coiled coil region
|
304 |
372 |
N/A |
INTRINSIC |
|
WD40
|
384 |
423 |
8.35e-11 |
SMART |
|
WD40
|
427 |
464 |
8.42e-7 |
SMART |
|
WD40
|
467 |
503 |
2.09e-2 |
SMART |
|
WD40
|
508 |
544 |
1.92e0 |
SMART |
|
WD40
|
547 |
584 |
5.15e-2 |
SMART |
|
WD40
|
587 |
628 |
1.78e-5 |
SMART |
|
WD40
|
631 |
668 |
1.63e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000175698
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000175732
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176086
|
| SMART Domains |
Protein: ENSMUSP00000135845
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
103 |
132 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176178
|
| SMART Domains |
Protein: ENSMUSP00000134808
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000176530
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000176805
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000177024
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000176633
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000176900
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176324
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177154
|
| SMART Domains |
Protein: ENSMUSP00000135874
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
91 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
118 |
N/A |
INTRINSIC |
|
RING
|
131 |
164 |
4.73e-6 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177193
|
| SMART Domains |
Protein: ENSMUSP00000135288
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
90 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
117 |
N/A |
INTRINSIC |
|
RING
|
130 |
163 |
4.73e-6 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176353
|
| SMART Domains |
Protein: ENSMUSP00000135267
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
RING
|
92 |
125 |
4.73e-6 |
SMART |
|
coiled coil region
|
264 |
332 |
N/A |
INTRINSIC |
|
WD40
|
344 |
383 |
8.35e-11 |
SMART |
|
WD40
|
387 |
424 |
8.42e-7 |
SMART |
|
WD40
|
427 |
463 |
2.09e-2 |
SMART |
|
WD40
|
468 |
504 |
1.92e0 |
SMART |
|
WD40
|
507 |
544 |
5.15e-2 |
SMART |
|
WD40
|
547 |
588 |
1.78e-5 |
SMART |
|
WD40
|
591 |
628 |
1.63e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176652
|
| SMART Domains |
Protein: ENSMUSP00000134759
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
low complexity region
|
90 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
109 |
117 |
N/A |
INTRINSIC |
|
RING
|
130 |
163 |
4.73e-6 |
SMART |
|
coiled coil region
|
304 |
372 |
N/A |
INTRINSIC |
|
WD40
|
384 |
423 |
8.35e-11 |
SMART |
|
WD40
|
427 |
464 |
8.42e-7 |
SMART |
|
WD40
|
467 |
503 |
2.09e-2 |
SMART |
|
WD40
|
508 |
544 |
1.92e0 |
SMART |
|
WD40
|
547 |
584 |
5.15e-2 |
SMART |
|
WD40
|
587 |
628 |
1.78e-5 |
SMART |
|
WD40
|
631 |
668 |
1.63e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177401
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176668
|
| SMART Domains |
Protein: ENSMUSP00000135586
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176237
|
| SMART Domains |
Protein: ENSMUSP00000134946
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
RING
|
91 |
124 |
4.73e-6 |
SMART |
|
Pfam:zf-TRAF
|
182 |
238 |
8.4e-9 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177025
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177405
|
| SMART Domains |
Protein: ENSMUSP00000135127
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
31 |
44 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177502
|
| SMART Domains |
Protein: ENSMUSP00000134970
Gene: ENSMUSG00000052752
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
11 |
N/A |
INTRINSIC |
|
RING
|
24 |
68 |
4.24e-2 |
SMART |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.0%
|
| Validation Efficiency |
100% (74/74) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Tumor necrosis factor (TNF; see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs; a coiled-coil (leucine zipper) motif; and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.[supplied by OMIM, Apr 2004]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 66 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310022A10Rik |
T |
A |
7: 27,271,076 (GRCm39) |
I157N |
probably damaging |
Het |
| Adgrl3 |
T |
C |
5: 81,908,571 (GRCm39) |
Y1165H |
probably damaging |
Het |
| Adra2a |
A |
G |
19: 54,034,926 (GRCm39) |
D94G |
probably damaging |
Het |
| Akr1c20 |
T |
A |
13: 4,558,174 (GRCm39) |
K197* |
probably null |
Het |
| Ankrd65 |
C |
T |
4: 155,877,493 (GRCm39) |
H335Y |
possibly damaging |
Het |
| Axin2 |
T |
A |
11: 108,834,682 (GRCm39) |
L636Q |
probably damaging |
Het |
| Camk1g |
G |
T |
1: 193,038,652 (GRCm39) |
T90N |
probably benign |
Het |
| Cd177 |
C |
A |
7: 24,450,051 (GRCm39) |
C528F |
probably damaging |
Het |
| Cntnap5a |
A |
T |
1: 116,339,931 (GRCm39) |
D730V |
possibly damaging |
Het |
| Crtap |
T |
C |
9: 114,215,304 (GRCm39) |
D195G |
probably benign |
Het |
| Csn1s2b |
A |
G |
5: 87,966,952 (GRCm39) |
S74G |
possibly damaging |
Het |
| Cyp3a16 |
T |
C |
5: 145,392,922 (GRCm39) |
R128G |
possibly damaging |
Het |
| Dnah7a |
A |
G |
1: 53,464,367 (GRCm39) |
F3675L |
probably benign |
Het |
| Dram2 |
T |
A |
3: 106,478,992 (GRCm39) |
W195R |
probably damaging |
Het |
| E130308A19Rik |
C |
T |
4: 59,691,057 (GRCm39) |
P297L |
probably benign |
Het |
| Eif3i |
T |
C |
4: 129,489,066 (GRCm39) |
S83G |
probably benign |
Het |
| Gabra1 |
G |
A |
11: 42,024,488 (GRCm39) |
P396S |
probably damaging |
Het |
| Gipr |
T |
A |
7: 18,891,300 (GRCm39) |
Y459F |
possibly damaging |
Het |
| Gm11677 |
C |
T |
11: 111,615,537 (GRCm39) |
|
noncoding transcript |
Het |
| Gm6981 |
T |
C |
9: 51,914,056 (GRCm39) |
|
noncoding transcript |
Het |
| Grin2d |
T |
C |
7: 45,511,905 (GRCm39) |
D180G |
probably damaging |
Het |
| Hectd4 |
T |
G |
5: 121,444,170 (GRCm39) |
|
probably null |
Het |
| Hhat |
T |
C |
1: 192,369,287 (GRCm39) |
|
probably benign |
Het |
| Hoxa6 |
A |
G |
6: 52,183,400 (GRCm39) |
L215P |
possibly damaging |
Het |
| Hsf4 |
G |
A |
8: 106,001,384 (GRCm39) |
|
probably null |
Het |
| Igf1r |
G |
A |
7: 67,814,947 (GRCm39) |
A283T |
possibly damaging |
Het |
| Ighv15-2 |
A |
G |
12: 114,528,476 (GRCm39) |
S25P |
probably damaging |
Het |
| Inpp5a |
C |
T |
7: 139,057,921 (GRCm39) |
T43I |
probably benign |
Het |
| Kmt2c |
T |
A |
5: 25,648,823 (GRCm39) |
E82V |
probably damaging |
Het |
| Lrrc31 |
A |
G |
3: 30,741,526 (GRCm39) |
|
probably benign |
Het |
| Mdga2 |
A |
G |
12: 66,844,396 (GRCm39) |
|
probably null |
Het |
| Mefv |
G |
A |
16: 3,533,198 (GRCm39) |
P358S |
probably benign |
Het |
| Mrgpra9 |
A |
G |
7: 46,884,795 (GRCm39) |
F291L |
possibly damaging |
Het |
| Mtmr3 |
A |
G |
11: 4,438,435 (GRCm39) |
L673P |
probably benign |
Het |
| Muc19 |
T |
C |
15: 91,787,360 (GRCm39) |
|
noncoding transcript |
Het |
| Myo5b |
A |
T |
18: 74,877,752 (GRCm39) |
T1584S |
possibly damaging |
Het |
| Or1x6 |
A |
T |
11: 50,939,307 (GRCm39) |
R124S |
probably damaging |
Het |
| Or4z4 |
T |
C |
19: 12,076,731 (GRCm39) |
T91A |
probably benign |
Het |
| Palld |
G |
T |
8: 62,330,062 (GRCm39) |
R272S |
probably benign |
Het |
| Pcnx3 |
T |
A |
19: 5,737,158 (GRCm39) |
N144Y |
probably damaging |
Het |
| Prf1 |
A |
G |
10: 61,136,203 (GRCm39) |
K160E |
probably damaging |
Het |
| Rasgrp1 |
G |
A |
2: 117,122,190 (GRCm39) |
A400V |
probably benign |
Het |
| Rnf150 |
A |
G |
8: 83,590,781 (GRCm39) |
Y48C |
probably damaging |
Het |
| Rpl11 |
G |
T |
4: 135,777,599 (GRCm39) |
Q170K |
probably benign |
Het |
| Scin |
G |
A |
12: 40,131,763 (GRCm39) |
A257V |
possibly damaging |
Het |
| Scn7a |
C |
A |
2: 66,534,104 (GRCm39) |
A524S |
possibly damaging |
Het |
| Sim1 |
T |
C |
10: 50,859,881 (GRCm39) |
L581S |
probably benign |
Het |
| Skor1 |
T |
C |
9: 63,051,741 (GRCm39) |
T715A |
probably benign |
Het |
| Slc22a26 |
A |
G |
19: 7,767,500 (GRCm39) |
V301A |
probably benign |
Het |
| Sorcs1 |
T |
C |
19: 50,171,119 (GRCm39) |
Y923C |
probably damaging |
Het |
| Src |
T |
A |
2: 157,309,405 (GRCm39) |
M304K |
possibly damaging |
Het |
| Srgap3 |
A |
T |
6: 112,734,386 (GRCm39) |
|
probably benign |
Het |
| Stard3 |
G |
A |
11: 98,263,160 (GRCm39) |
E72K |
possibly damaging |
Het |
| Svep1 |
T |
A |
4: 58,070,340 (GRCm39) |
N2482I |
probably damaging |
Het |
| Tbc1d23 |
T |
C |
16: 57,038,778 (GRCm39) |
K20R |
possibly damaging |
Het |
| Tcstv4 |
A |
C |
13: 120,769,698 (GRCm39) |
K6T |
possibly damaging |
Het |
| Tfip11 |
G |
A |
5: 112,481,265 (GRCm39) |
E414K |
probably damaging |
Het |
| Tinag |
G |
T |
9: 76,904,232 (GRCm39) |
T397K |
possibly damaging |
Het |
| Trmt10b |
T |
A |
4: 45,305,817 (GRCm39) |
I164N |
probably damaging |
Het |
| Trpm1 |
A |
G |
7: 63,884,800 (GRCm39) |
D827G |
probably benign |
Het |
| Ube2u |
A |
T |
4: 100,343,855 (GRCm39) |
T85S |
probably benign |
Het |
| Ulk4 |
T |
C |
9: 120,932,642 (GRCm39) |
D1066G |
probably benign |
Het |
| Vmn2r72 |
T |
A |
7: 85,387,069 (GRCm39) |
I832F |
probably benign |
Het |
| Yipf1 |
A |
C |
4: 107,193,355 (GRCm39) |
E80D |
probably benign |
Het |
| Zfp40 |
T |
A |
17: 23,394,629 (GRCm39) |
R653W |
probably damaging |
Het |
| Zxdc |
A |
G |
6: 90,349,535 (GRCm39) |
T308A |
probably damaging |
Het |
|
| Other mutations in Traf7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01674:Traf7
|
APN |
17 |
24,729,349 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01821:Traf7
|
APN |
17 |
24,729,473 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02263:Traf7
|
APN |
17 |
24,732,020 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02307:Traf7
|
APN |
17 |
24,732,020 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02321:Traf7
|
APN |
17 |
24,732,020 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02323:Traf7
|
APN |
17 |
24,732,020 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02636:Traf7
|
APN |
17 |
24,731,964 (GRCm39) |
missense |
probably benign |
|
|
Antediluvian
|
UTSW |
17 |
24,729,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Caveman
|
UTSW |
17 |
24,728,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Oldhat
|
UTSW |
17 |
24,731,266 (GRCm39) |
missense |
probably benign |
0.28 |
|
R0109:Traf7
|
UTSW |
17 |
24,732,900 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0109:Traf7
|
UTSW |
17 |
24,732,900 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0193:Traf7
|
UTSW |
17 |
24,729,525 (GRCm39) |
missense |
probably benign |
0.22 |
|
R1426:Traf7
|
UTSW |
17 |
24,730,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1484:Traf7
|
UTSW |
17 |
24,730,785 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1574:Traf7
|
UTSW |
17 |
24,729,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1574:Traf7
|
UTSW |
17 |
24,729,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1728:Traf7
|
UTSW |
17 |
24,731,353 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1729:Traf7
|
UTSW |
17 |
24,731,353 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1784:Traf7
|
UTSW |
17 |
24,731,353 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1959:Traf7
|
UTSW |
17 |
24,732,255 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1994:Traf7
|
UTSW |
17 |
24,729,476 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2484:Traf7
|
UTSW |
17 |
24,730,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4682:Traf7
|
UTSW |
17 |
24,732,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4778:Traf7
|
UTSW |
17 |
24,729,412 (GRCm39) |
unclassified |
probably benign |
|
|
R4779:Traf7
|
UTSW |
17 |
24,729,412 (GRCm39) |
unclassified |
probably benign |
|
|
R5120:Traf7
|
UTSW |
17 |
24,737,718 (GRCm39) |
nonsense |
probably null |
|
|
R6594:Traf7
|
UTSW |
17 |
24,728,813 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6885:Traf7
|
UTSW |
17 |
24,731,266 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7396:Traf7
|
UTSW |
17 |
24,728,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7669:Traf7
|
UTSW |
17 |
24,732,282 (GRCm39) |
nonsense |
probably null |
|
|
R7707:Traf7
|
UTSW |
17 |
24,729,683 (GRCm39) |
splice site |
probably null |
|
|
R8087:Traf7
|
UTSW |
17 |
24,731,038 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R8557:Traf7
|
UTSW |
17 |
24,729,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8932:Traf7
|
UTSW |
17 |
24,731,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Traf7
|
UTSW |
17 |
24,746,737 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R9539:Traf7
|
UTSW |
17 |
24,729,333 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9679:Traf7
|
UTSW |
17 |
24,746,737 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R9680:Traf7
|
UTSW |
17 |
24,746,737 (GRCm39) |
critical splice donor site |
probably benign |
|
|
Z1177:Traf7
|
UTSW |
17 |
24,728,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAGAGCCACTGTACAGATAGC -3'
(R):5'- ACCATCATTGTGAGTGGGCAC -3'
Sequencing Primer
(F):5'- CTCTGTGCTGCCACCAG -3'
(R):5'- CGAGAAGACCCATTGCTCTTTC -3'
|
| Posted On |
2015-12-29 |
Incidental Mutation