Incidental Mutation 'R0412:Wdr87-ps'
ID 36716
Institutional Source Beutler Lab
Gene Symbol Wdr87-ps
Ensembl Gene ENSMUSG00000074224
Gene Name WD repeat domain 87, pseudogene
Synonyms 4932431P20Rik
MMRRC Submission 038614-MU
Accession Numbers
Essential gene? Non essential (E-score: 0.000) question?
Stock # R0412 (G1)
Quality Score 225
Status Validated
Chromosome 7
Chromosomal Location 29223968-29237480 bp(+) (GRCm39)
Type of Mutation exon
DNA Base Change (assembly) C to G at 29229995 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
AlphaFold no structure available at present
Predicted Effect noncoding transcript
Transcript: ENSMUST00000141713
SMART Domains Protein: ENSMUSP00000120285
Gene: ENSMUSG00000074224

DomainStartEndE-ValueType
Blast:WD40 94 134 1e-9 BLAST
WD40 139 176 1.59e1 SMART
WD40 228 269 9.51e1 SMART
WD40 272 311 3.33e-1 SMART
Blast:WD40 354 393 4e-15 BLAST
Blast:WD40 445 490 2e-22 BLAST
Blast:WD40 493 538 8e-15 BLAST
WD40 595 634 1.68e-6 SMART
low complexity region 701 710 N/A INTRINSIC
low complexity region 915 926 N/A INTRINSIC
coiled coil region 1135 1168 N/A INTRINSIC
low complexity region 1211 1230 N/A INTRINSIC
low complexity region 1239 1273 N/A INTRINSIC
coiled coil region 1347 1375 N/A INTRINSIC
coiled coil region 1399 1433 N/A INTRINSIC
low complexity region 1435 1453 N/A INTRINSIC
low complexity region 1497 1519 N/A INTRINSIC
coiled coil region 1612 1707 N/A INTRINSIC
coiled coil region 1731 1989 N/A INTRINSIC
coiled coil region 2034 2072 N/A INTRINSIC
coiled coil region 2127 2154 N/A INTRINSIC
coiled coil region 2220 2302 N/A INTRINSIC
coiled coil region 2357 2561 N/A INTRINSIC
low complexity region 2993 2999 N/A INTRINSIC
Meta Mutation Damage Score 0.0869 question?
Coding Region Coverage
  • 1x: 99.1%
  • 3x: 98.2%
  • 10x: 95.8%
  • 20x: 90.2%
Validation Efficiency 94% (67/71)
Allele List at MGI
Other mutations in this stock
Total: 61 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Arap1 C A 7: 101,039,429 (GRCm39) A563D probably damaging Het
Arhgap28 G A 17: 68,203,253 (GRCm39) L67F probably damaging Het
Atp7b G T 8: 22,485,675 (GRCm39) probably null Het
Auts2 A G 5: 131,475,669 (GRCm39) F485L probably benign Het
Ccdc68 A G 18: 70,093,510 (GRCm39) E239G probably damaging Het
Cdc42bpg T G 19: 6,363,487 (GRCm39) L449R probably damaging Het
Colgalt2 G T 1: 152,384,312 (GRCm39) A551S possibly damaging Het
Ddx41 G T 13: 55,678,421 (GRCm39) S630Y probably damaging Het
Dntt T C 19: 41,031,372 (GRCm39) L274P probably damaging Het
Fhl4 G T 10: 84,934,680 (GRCm39) H34N possibly damaging Het
Filip1 A T 9: 79,727,571 (GRCm39) N349K possibly damaging Het
Gm9894 C T 13: 67,913,145 (GRCm39) noncoding transcript Het
Gpr179 A G 11: 97,229,633 (GRCm39) S841P probably damaging Het
Gpr35 G T 1: 92,910,506 (GRCm39) V73L probably benign Het
Grik5 A G 7: 24,713,099 (GRCm39) V809A possibly damaging Het
H2-T13 T A 17: 36,392,413 (GRCm39) probably benign Het
Heatr5b T C 17: 79,128,283 (GRCm39) T451A probably benign Het
Hmcn2 G A 2: 31,278,259 (GRCm39) V1654M probably damaging Het
Htra3 G T 5: 35,828,409 (GRCm39) A157E probably damaging Het
Igf2r A T 17: 12,902,835 (GRCm39) V2405D probably damaging Het
Irs3 C A 5: 137,642,139 (GRCm39) R433L probably benign Het
Kcmf1 G A 6: 72,825,224 (GRCm39) Q239* probably null Het
Kcnk9 A G 15: 72,384,905 (GRCm39) probably benign Het
Kif28 A G 1: 179,530,091 (GRCm39) V622A probably benign Het
Klrb1f A T 6: 129,031,294 (GRCm39) I164F probably benign Het
Lama2 A G 10: 27,066,621 (GRCm39) S1087P possibly damaging Het
Mchr1 A T 15: 81,119,948 (GRCm39) probably benign Het
Mcidas A G 13: 113,135,677 (GRCm39) T367A probably damaging Het
Mphosph8 A C 14: 56,911,870 (GRCm39) K298Q probably damaging Het
Mroh2a G T 1: 88,162,938 (GRCm39) Q360H probably benign Het
Mst1 A C 9: 107,960,793 (GRCm39) D461A probably benign Het
Nckap1l A T 15: 103,373,079 (GRCm39) S311C probably benign Het
Or2y1 T A 11: 49,385,594 (GRCm39) V78E probably damaging Het
Or4c125 T A 2: 89,170,422 (GRCm39) M75L probably benign Het
Or5m9b C T 2: 85,905,435 (GRCm39) A117V probably benign Het
Or8c11 A C 9: 38,290,090 (GRCm39) K298N probably damaging Het
Pde3a T G 6: 141,444,410 (GRCm39) C1073G probably damaging Het
Pkhd1 T C 1: 20,188,012 (GRCm39) D3432G probably damaging Het
Ppargc1b G T 18: 61,448,932 (GRCm39) P130Q probably damaging Het
Ppp6r1 A G 7: 4,645,213 (GRCm39) I228T probably damaging Het
Pram1 A G 17: 33,860,480 (GRCm39) N349S probably benign Het
Ranbp6 C T 19: 29,789,483 (GRCm39) V290I possibly damaging Het
Rcan3 A T 4: 135,143,914 (GRCm39) probably null Het
Scn8a G C 15: 100,906,187 (GRCm39) probably benign Het
Slc12a5 C T 2: 164,835,982 (GRCm39) T900M probably benign Het
Srsf10 A G 4: 135,585,714 (GRCm39) Y55C probably damaging Het
Syt7 G T 19: 10,421,444 (GRCm39) E450* probably null Het
Tbrg4 T C 11: 6,573,832 (GRCm39) K130R probably benign Het
Tgm7 C A 2: 120,931,546 (GRCm39) V206F probably damaging Het
Tmem131l T C 3: 83,938,955 (GRCm39) D67G probably damaging Het
Ttc7 A G 17: 87,637,472 (GRCm39) K409R probably benign Het
Unc80 A T 1: 66,590,096 (GRCm39) probably benign Het
Vmn1r171 C T 7: 23,332,080 (GRCm39) L102F possibly damaging Het
Vmn2r59 A C 7: 41,695,916 (GRCm39) probably benign Het
Vsig2 A G 9: 37,453,986 (GRCm39) R191G probably damaging Het
Wdr86 T A 5: 24,923,232 (GRCm39) Q153H probably benign Het
Xxylt1 T A 16: 30,826,616 (GRCm39) N233I probably damaging Het
Zfp160 A T 17: 21,247,139 (GRCm39) E563V probably damaging Het
Zfp345 T A 2: 150,315,323 (GRCm39) E71D probably benign Het
Zfp541 A G 7: 15,816,099 (GRCm39) D862G possibly damaging Het
Zfp639 A C 3: 32,571,259 (GRCm39) Q47P possibly damaging Het
Other mutations in Wdr87-ps
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00272:Wdr87-ps APN 7 29,237,047 (GRCm39) exon noncoding transcript
IGL00505:Wdr87-ps APN 7 29,233,608 (GRCm39) exon noncoding transcript
IGL00557:Wdr87-ps APN 7 29,235,227 (GRCm39) exon noncoding transcript
IGL00569:Wdr87-ps APN 7 29,233,565 (GRCm39) exon noncoding transcript
IGL00966:Wdr87-ps APN 7 29,236,888 (GRCm39) exon noncoding transcript
IGL01668:Wdr87-ps APN 7 29,236,855 (GRCm39) exon noncoding transcript
K7371:Wdr87-ps UTSW 7 29,230,417 (GRCm39) exon noncoding transcript
P0037:Wdr87-ps UTSW 7 29,233,039 (GRCm39) exon noncoding transcript
R0179:Wdr87-ps UTSW 7 29,235,365 (GRCm39) exon noncoding transcript
R0357:Wdr87-ps UTSW 7 29,235,007 (GRCm39) exon noncoding transcript
R0358:Wdr87-ps UTSW 7 29,231,636 (GRCm39) exon noncoding transcript
R0530:Wdr87-ps UTSW 7 29,229,545 (GRCm39) exon noncoding transcript
R0600:Wdr87-ps UTSW 7 29,232,690 (GRCm39) exon noncoding transcript
R0675:Wdr87-ps UTSW 7 29,231,942 (GRCm39) exon noncoding transcript
R1118:Wdr87-ps UTSW 7 29,233,669 (GRCm39) exon noncoding transcript
R1395:Wdr87-ps UTSW 7 29,230,812 (GRCm39) exon noncoding transcript
R1444:Wdr87-ps UTSW 7 29,229,380 (GRCm39) exon noncoding transcript
R1476:Wdr87-ps UTSW 7 29,234,315 (GRCm39) exon noncoding transcript
R1534:Wdr87-ps UTSW 7 29,229,854 (GRCm39) exon noncoding transcript
R1535:Wdr87-ps UTSW 7 29,229,004 (GRCm39) exon noncoding transcript
R2023:Wdr87-ps UTSW 7 29,230,959 (GRCm39) exon noncoding transcript
R2127:Wdr87-ps UTSW 7 29,236,565 (GRCm39) exon noncoding transcript
R2141:Wdr87-ps UTSW 7 29,230,935 (GRCm39) exon noncoding transcript
R2198:Wdr87-ps UTSW 7 29,226,697 (GRCm39) exon noncoding transcript
R2201:Wdr87-ps UTSW 7 29,235,950 (GRCm39) exon noncoding transcript
R2262:Wdr87-ps UTSW 7 29,231,987 (GRCm39) exon noncoding transcript
R2263:Wdr87-ps UTSW 7 29,231,987 (GRCm39) exon noncoding transcript
R4874:Wdr87-ps UTSW 7 29,235,608 (GRCm39) exon noncoding transcript
R5064:Wdr87-ps UTSW 7 29,235,080 (GRCm39) exon noncoding transcript
R5130:Wdr87-ps UTSW 7 29,228,699 (GRCm39) exon noncoding transcript
R5366:Wdr87-ps UTSW 7 29,232,964 (GRCm39) exon noncoding transcript
Predicted Primers PCR Primer
(F):5'- TTGACTGCCTGGGACGGATTGAAC -3'
(R):5'- GCATGGCCCATGATGCTGAGAATTG -3'

Sequencing Primer
(F):5'- GGATTGAACCCCTATCAGATACTTGG -3'
(R):5'- GAATTGCCTCGATCAGGCTAC -3'
Posted On 2013-05-09